DE69840230D1 - Polypeptide mit prolyldipeptidylaminopeptidase-aktivität und dafür kodierende nukleinsäuren - Google Patents

Polypeptide mit prolyldipeptidylaminopeptidase-aktivität und dafür kodierende nukleinsäuren

Info

Publication number
DE69840230D1
DE69840230D1 DE69840230T DE69840230T DE69840230D1 DE 69840230 D1 DE69840230 D1 DE 69840230D1 DE 69840230 T DE69840230 T DE 69840230T DE 69840230 T DE69840230 T DE 69840230T DE 69840230 D1 DE69840230 D1 DE 69840230D1
Authority
DE
Germany
Prior art keywords
polypeptides
activity
prolyldipeptidylaminopeptidase
code
nucleic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69840230T
Other languages
German (de)
English (en)
Inventor
Alexander Blinkovsky
Kimberly Brown
Michael W Rey
Alan Klotz
Tony Byun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novozymes Inc
Original Assignee
Novozymes Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26742833&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69840230(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novozymes Inc filed Critical Novozymes Inc
Application granted granted Critical
Publication of DE69840230D1 publication Critical patent/DE69840230D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT OF FLOUR OR DOUGH FOR BAKING, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS
    • A21D2/00—Treatment of flour or dough by adding materials thereto before or during baking
    • A21D2/08—Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
    • A21D2/24—Organic nitrogen compounds
    • A21D2/26—Proteins
    • A21D2/267—Microbial proteins
    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT OF FLOUR OR DOUGH FOR BAKING, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS
    • A21D8/00—Methods for preparing or baking dough
    • A21D8/02—Methods for preparing dough; Treating dough prior to baking
    • A21D8/04—Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes
    • A21D8/042—Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes with enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/20—Synthetic spices, flavouring agents or condiments
    • A23L27/21—Synthetic spices, flavouring agents or condiments containing amino acids

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Nutrition Science (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69840230T 1997-05-16 1998-05-12 Polypeptide mit prolyldipeptidylaminopeptidase-aktivität und dafür kodierende nukleinsäuren Expired - Lifetime DE69840230D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85788497A 1997-05-16 1997-05-16
US6289297P 1997-10-20 1997-10-20
PCT/US1998/009629 WO1998051803A1 (en) 1997-05-16 1998-05-12 Polypeptides having prolyl pipeptidyl aminopeptidase activity and nucleic acids encoding same

Publications (1)

Publication Number Publication Date
DE69840230D1 true DE69840230D1 (de) 2009-01-02

Family

ID=26742833

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69840230T Expired - Lifetime DE69840230D1 (de) 1997-05-16 1998-05-12 Polypeptide mit prolyldipeptidylaminopeptidase-aktivität und dafür kodierende nukleinsäuren

Country Status (9)

Country Link
US (2) US6664092B1 (https=)
EP (1) EP0981630B1 (https=)
JP (1) JP4050329B2 (https=)
CN (1) CN1227363C (https=)
AT (1) ATE414775T1 (https=)
AU (1) AU7381098A (https=)
DE (1) DE69840230D1 (https=)
DK (1) DK0981630T3 (https=)
WO (1) WO1998051803A1 (https=)

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JP3727780B2 (ja) * 1998-06-12 2005-12-14 キッコーマン株式会社 ロイシンアミノペプチダーゼ遺伝子、組み換え体ｄｎａ及びロイシンアミノペプチダーゼの製造法
WO2002077223A1 (fr) 2001-03-19 2002-10-03 Ajinomoto Co.,Inc. Nouvelle aminopeptidase et son gene
US7186540B2 (en) * 2001-12-27 2007-03-06 National Institute of Advanced Indusrtial Science and Technology Thermostable glutaminase and thermostable glutaminase gene
ES2540926T3 (es) * 2002-06-04 2015-07-14 Dsm Ip Assets B.V. Hidrolizado de proteínas rico en tripéptidos
JP4300289B2 (ja) * 2002-08-27 2009-07-22 国立大学法人 岡山大学 加水分解又は脱水縮合酵素、及び当該酵素の生産方法、並びに当該酵素を用いたアミドの合成方法
US7550590B2 (en) 2003-03-25 2009-06-23 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
WO2004103993A1 (en) 2003-05-14 2004-12-02 Syrrx, Inc. Dipeptidyl peptidase inhibitors
JP5341300B2 (ja) 2003-08-01 2013-11-13 カルピス株式会社 アンジオテンシン変換酵素阻害活性又は血圧降下作用を有する剤
US7678909B1 (en) 2003-08-13 2010-03-16 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
KR20060041309A (ko) 2003-08-13 2006-05-11 다케다 야쿠힌 고교 가부시키가이샤 ４-피리미돈 유도체 및 펩티딜 펩티다제 저해제로서의 그의용도
US7169926B1 (en) 2003-08-13 2007-01-30 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
US7790734B2 (en) 2003-09-08 2010-09-07 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
US7732446B1 (en) 2004-03-11 2010-06-08 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
CN102127057A (zh) 2004-03-15 2011-07-20 武田药品工业株式会社 二肽基肽酶抑制剂
JP2008501714A (ja) 2004-06-04 2008-01-24 武田薬品工業株式会社 ジペプチジルペプチダーゼインヒビター
WO2006019965A2 (en) 2004-07-16 2006-02-23 Takeda San Diego, Inc. Dipeptidyl peptidase inhibitors
WO2006068978A2 (en) 2004-12-21 2006-06-29 Takeda Pharmaceutial Company Limited Dipeptidyl peptidase inhibitors
GEP20135838B (en) 2005-09-14 2013-06-10 Takeda Pharmaceutical Dipeptidyl peptidase inhibitors usage at diabetes treatment
CN101360723A (zh) 2005-09-16 2009-02-04 武田药品工业株式会社 制备嘧啶二酮衍生物的方法
WO2007112347A1 (en) 2006-03-28 2007-10-04 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
US8324383B2 (en) 2006-09-13 2012-12-04 Takeda Pharmaceutical Company Limited Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
TW200838536A (en) 2006-11-29 2008-10-01 Takeda Pharmaceutical Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
US8093236B2 (en) 2007-03-13 2012-01-10 Takeda Pharmaceuticals Company Limited Weekly administration of dipeptidyl peptidase inhibitors
US9493759B2 (en) 2008-12-12 2016-11-15 Novozymes, Inc. Polypeptides having aspartic endopeptidase activity and polynucleotides encoding same
EP2398822B1 (en) * 2009-02-19 2013-01-02 Novo Nordisk A/S Modification of factor viii
JP5759132B2 (ja) * 2010-09-21 2015-08-05 月桂冠株式会社 糸状菌ペプチダーゼの生産方法
WO2013092731A1 (en) * 2011-12-21 2013-06-27 Dsm Ip Assets B.V. Method for making a dough with a glutamyl endopeptidase
CN103695361B (zh) * 2013-12-06 2015-11-11 江南大学 一种生产脯氨酸氨肽酶的基因工程菌及其构建方法
GB201705750D0 (en) * 2017-04-10 2017-05-24 Univ Oxford Innovation Ltd Peptide ligase and use therof
EP4273249A3 (en) * 2023-07-07 2024-05-22 Novozymes A/S Improved expression of recombinant proteins

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US3857967A (en) 1971-05-10 1974-12-31 Kikkoman Shoyu Co Ltd Preparation of food and beverages with peptidoglutaminase
US4288627A (en) 1980-02-12 1981-09-08 Phillips Petroleum Company Oxidation of thiols employing cobalt molybdate/triethylamine catalyst
JPS61279528A (ja) 1985-06-05 1986-12-10 Hokkai Can Co Ltd 容器の製造方法
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
JPH0665280B2 (ja) 1987-03-04 1994-08-24 味の素株式会社 タンパクゲル化剤及びそれを用いるタンパクのゲル化方法
JPS6450382A (en) 1987-08-20 1989-02-27 Hitachi Heating Appl Plane-form heating body
EP0471265B1 (en) 1988-01-07 1995-10-25 Novo Nordisk A/S Specific protease
NL194258C (nl) * 1989-09-01 2001-11-05 Protein Technologies Internat Werkwijze voor het behandelen van een eiwithoudend materiaal.
JP3153237B2 (ja) 1990-03-09 2001-04-03 ノボ ノルディスク アクティーゼルスカブ タンパク質加水分解物
CA2082279C (en) 1990-05-09 2007-09-04 Grethe Rasmussen Cellulase preparation comprising an endoglucanase enzyme
US5641670A (en) 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
EP0555649B1 (en) 1992-01-14 2004-12-08 Ajinomoto Co., Inc. Gene encoding transglutaminase derived from fish
AU665805B2 (en) 1992-01-22 1996-01-18 Novo Nordisk A/S Activated factor XIII
CN1057127C (zh) * 1993-04-23 2000-10-04 北京大学 固定化复合外肽酶蛋白质全水解及脱苦方法
DK46793D0 (da) 1993-04-26 1993-04-26 Novo Nordisk As Enzym
DK52393D0 (https=) 1993-05-05 1993-05-05 Novo Nordisk As
DK52293D0 (https=) 1993-05-05 1993-05-05 Novo Nordisk As
JPH07115969A (ja) * 1993-10-25 1995-05-09 Asahi Chem Ind Co Ltd 加水分解蛋白質の製造方法
WO1995033836A1 (en) 1994-06-03 1995-12-14 Novo Nordisk Biotech, Inc. Phosphonyldipeptides useful in the treatment of cardiovascular diseases
ATE294871T1 (de) 1994-06-30 2005-05-15 Novozymes Biotech Inc Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren
DE69535037T2 (de) 1994-08-26 2006-12-07 Novozymes A/S Mikrobielle transglutaminasen, ihre herstellung und ihre verwendung
WO1996022366A1 (en) 1995-01-19 1996-07-25 Novo Nordisk A/S Transglutaminases from oomycetes
AU4939396A (en) 1995-03-16 1996-10-02 Novo Nordisk A/S An enzyme with aminopeptidase activity
CN1099839C (zh) * 1996-05-20 2003-01-29 诺沃奇梅兹有限公司 一种获得蛋白质水解物的方法

Also Published As

Publication number Publication date
JP4050329B2 (ja) 2008-02-20
CN1268976A (zh) 2000-10-04
CN1227363C (zh) 2005-11-16
US7098001B2 (en) 2006-08-29
AU7381098A (en) 1998-12-08
JP2002511746A (ja) 2002-04-16
US6664092B1 (en) 2003-12-16
US20040171104A1 (en) 2004-09-02
WO1998051803A1 (en) 1998-11-19
EP0981630B1 (en) 2008-11-19
ATE414775T1 (de) 2008-12-15
EP0981630A1 (en) 2000-03-01
DK0981630T3 (da) 2009-03-09

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