JP4047724B2 - ピペラジン誘導体 - Google Patents

ピペラジン誘導体 Download PDF

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Publication number
JP4047724B2
JP4047724B2 JP2002549655A JP2002549655A JP4047724B2 JP 4047724 B2 JP4047724 B2 JP 4047724B2 JP 2002549655 A JP2002549655 A JP 2002549655A JP 2002549655 A JP2002549655 A JP 2002549655A JP 4047724 B2 JP4047724 B2 JP 4047724B2
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Japan
Prior art keywords
piperazine
carboxylic acid
cis
fluoro
tert
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Expired - Fee Related
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JP2002549655A
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Japanese (ja)
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JP2004519438A (ja
JP2004519438A5 (https=
Inventor
アダムス，デービッド・レジナルド
ベントレー，ジョナサン・マーク
デービッドソン，ジェームス・エドワード・ポール
ドーソン，クレア・エリザベス
ジョージ，アシュレー・ロジャー
マンセル，ハワード・ランガム
マタイ，パトリツィオ
ミズラヒ，ヤック
ネッテコフェン，マサイアス・ハインリヒ
プラット，ロバート・マーク
ロフィー，ジョナサン・リチャード・アンソニー
ローバー，シュテファン
スペクラン，ジャン−リュック
スタルダー，ヘンリ
ウィルキンソン，ケリー
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
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