JP4045276B2 - 表面に活性化されたカルボキシル基を有する固体基板を利用して生体分子を前記固体基板上に高密度で固定化する方法及びそれによって製造されるマイクロアレイ - Google Patents
表面に活性化されたカルボキシル基を有する固体基板を利用して生体分子を前記固体基板上に高密度で固定化する方法及びそれによって製造されるマイクロアレイ Download PDFInfo
- Publication number
- JP4045276B2 JP4045276B2 JP2005005638A JP2005005638A JP4045276B2 JP 4045276 B2 JP4045276 B2 JP 4045276B2 JP 2005005638 A JP2005005638 A JP 2005005638A JP 2005005638 A JP2005005638 A JP 2005005638A JP 4045276 B2 JP4045276 B2 JP 4045276B2
- Authority
- JP
- Japan
- Prior art keywords
- group
- dianhydride
- solid support
- anhydride
- biomolecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/97—Test strip or test slide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020040001963A KR100580642B1 (ko) | 2004-01-12 | 2004-01-12 | 표면에 활성화된 카르복실기를 갖는 기판을 이용하여 생물분자를 고체 기판상에 고밀도로 고정화하는 방법 및 그에 의하여 제조되는 마이크로어레이 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005201901A JP2005201901A (ja) | 2005-07-28 |
| JP2005201901A5 JP2005201901A5 (enExample) | 2006-04-20 |
| JP4045276B2 true JP4045276B2 (ja) | 2008-02-13 |
Family
ID=34588143
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005005638A Expired - Fee Related JP4045276B2 (ja) | 2004-01-12 | 2005-01-12 | 表面に活性化されたカルボキシル基を有する固体基板を利用して生体分子を前記固体基板上に高密度で固定化する方法及びそれによって製造されるマイクロアレイ |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7195924B2 (enExample) |
| EP (1) | EP1553415B1 (enExample) |
| JP (1) | JP4045276B2 (enExample) |
| KR (1) | KR100580642B1 (enExample) |
| CN (1) | CN100392099C (enExample) |
| DE (1) | DE602005000189T2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100657907B1 (ko) * | 2004-11-03 | 2006-12-14 | 삼성전자주식회사 | 신규한 링커 화합물, 상기 화합물이 코팅되어 있는 기판,상기 화합물을 이용하여 마이크로어레이를 제조하는 방법및 그에 의하여 제조된 마이크로어레이 |
| GB2420849B (en) * | 2004-12-02 | 2007-06-27 | Schlumberger Holdings | Optical pH sensor |
| KR100738083B1 (ko) * | 2005-12-20 | 2007-07-12 | 삼성전자주식회사 | 마이크로어레이용 기판 및 그의 제조방법 |
| KR100829574B1 (ko) | 2006-01-03 | 2008-05-14 | 삼성전자주식회사 | 마이크로어레이용 기판, 그 마이크로어레이용 기판을이용하여 생분자를 분석하는 방법, 및 그 마이크로어레이용기판을 포함하는 랩온어칩 |
| US7493199B2 (en) * | 2006-10-17 | 2009-02-17 | Trw Automotive U.S. Llc | Method of controlling a roll control system for improved vehicle dynamic control |
| KR100843147B1 (ko) * | 2007-02-12 | 2008-07-03 | 삼성전자주식회사 | 올리고머 프로브 어레이용 기판과 올리고머 프로브 어레이및 이들의 제조 방법 |
| JP4805283B2 (ja) * | 2007-03-22 | 2011-11-02 | 信越化学工業株式会社 | マイクロアレイ作製用基板の製造方法 |
| JP5388462B2 (ja) * | 2008-03-24 | 2014-01-15 | 富士フイルム株式会社 | 担体及びその製造方法 |
| JP5344835B2 (ja) * | 2008-03-24 | 2013-11-20 | 富士フイルム株式会社 | 固定化方法、生理活性物質固定化担体及び固定用担体 |
| EP2270507A4 (en) | 2008-03-24 | 2013-02-27 | Fujifilm Corp | IMMOBILIZING METHOD, PHYSIOLOGICALLY ACTIVE SUBSTANCE SUPPORTING MEDIUM, HOLDING MEDIUM, SUPPORT AND SUPPORT MANUFACTURING METHOD |
| DE102010049807A1 (de) | 2010-10-27 | 2012-05-03 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren zur Immobilisierung mindestens einer Substanz auf Oberflächen |
| JP5462919B2 (ja) * | 2011-10-31 | 2014-04-02 | アークレイ株式会社 | 基材の修飾方法 |
| CN104027852B (zh) * | 2014-06-26 | 2015-09-23 | 淮阴工学院 | 生物材料的表面改性方法 |
| KR101603602B1 (ko) | 2014-07-09 | 2016-03-16 | 한국원자력연구원 | 방사선 조사를 이용한 폴리도파민 코팅 고분자 기질 및 이의 제조 방법 |
| CN105854962B (zh) * | 2016-03-28 | 2018-01-19 | 北京瑞联安科技有限公司 | 一种生物识别分子固定到生物芯片的方法 |
| US11312831B2 (en) | 2016-11-18 | 2022-04-26 | Toyo Seikan Group Holdings, Ltd. | Carrier for bio-related molecule immobilization |
| JP2018078864A (ja) * | 2016-11-18 | 2018-05-24 | 東洋製罐グループホールディングス株式会社 | 生体関連分子固定化用担体 |
| JP6931181B2 (ja) * | 2016-12-20 | 2021-09-01 | 東洋製罐グループホールディングス株式会社 | 生体関連分子固定化用担体 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1259312A (en) * | 1985-11-11 | 1989-09-12 | Jaroslav Kahovec | Silane reagents containing a complexion grouping and inorganic material modified with these reagents |
| JPH0637609B2 (ja) * | 1986-01-24 | 1994-05-18 | マサチユ−セツツ インスチチユ−ト オブ テクノロジ− | 接着促進剤 |
| FR2630329B1 (fr) * | 1988-04-20 | 1991-07-05 | Merieux Inst | Conjugues macromoleculaires d'hemoglobine, leur procede de preparation et leurs applications |
| DE3814370A1 (de) | 1988-04-28 | 1989-11-09 | Boehringer Mannheim Gmbh | Testtraeger fuer die analyse einer probenfluessigkeit, verfahren zur durchfuehrung einer solchen analyse und herstellungsverfahren |
| US5744101A (en) * | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
| US5143854A (en) * | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| JP2979414B2 (ja) | 1989-09-29 | 1999-11-15 | 富士レビオ株式会社 | 磁性粒子およびそれを用いた免疫測定法 |
| CA2064683A1 (en) * | 1992-03-26 | 1993-09-27 | Krishna Mohan Rao Kallury | Formation of thermostable enzymes with extra-ordinary heat tolerance by immobilization on phospholipid matrices |
| US5350800A (en) * | 1993-01-19 | 1994-09-27 | Medtronic, Inc. | Method for improving the biocompatibility of solid surfaces |
| US5643721A (en) * | 1994-02-09 | 1997-07-01 | Abbott Laboratories | Bioreagent immobilization medium |
| US5760130A (en) * | 1997-05-13 | 1998-06-02 | Molecular Dynamics, Inc. | Aminosilane/carbodiimide coupling of DNA to glass substrate |
| US6506594B1 (en) * | 1999-03-19 | 2003-01-14 | Cornell Res Foundation Inc | Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays |
| US6413722B1 (en) | 2000-03-22 | 2002-07-02 | Incyte Genomics, Inc. | Polymer coated surfaces for microarray applications |
| US6528264B1 (en) * | 2000-11-01 | 2003-03-04 | Corning Incorporated | Polymer support for DNA immobilization |
| US6989267B2 (en) * | 2001-07-02 | 2006-01-24 | Agilent Technologies, Inc. | Methods of making microarrays with substrate surfaces having covalently bound polyelectrolyte films |
| JP2003261823A (ja) * | 2002-03-12 | 2003-09-19 | Mitsui Chemicals Inc | 多孔質膜形成用塗布液の製造方法および該塗布液、並びに多孔質膜の製造方法および多孔質膜 |
-
2004
- 2004-01-12 KR KR1020040001963A patent/KR100580642B1/ko not_active Expired - Fee Related
-
2005
- 2005-01-04 US US11/028,822 patent/US7195924B2/en not_active Expired - Fee Related
- 2005-01-07 DE DE602005000189T patent/DE602005000189T2/de not_active Expired - Lifetime
- 2005-01-07 EP EP05000285A patent/EP1553415B1/en not_active Expired - Lifetime
- 2005-01-12 JP JP2005005638A patent/JP4045276B2/ja not_active Expired - Fee Related
- 2005-01-12 CN CNB2005100044744A patent/CN100392099C/zh not_active Expired - Fee Related
-
2007
- 2007-02-23 US US11/678,275 patent/US20070141556A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20070141556A1 (en) | 2007-06-21 |
| US20050153350A1 (en) | 2005-07-14 |
| CN100392099C (zh) | 2008-06-04 |
| DE602005000189T2 (de) | 2007-02-08 |
| KR20050073856A (ko) | 2005-07-18 |
| EP1553415B1 (en) | 2006-10-25 |
| JP2005201901A (ja) | 2005-07-28 |
| DE602005000189D1 (de) | 2006-12-07 |
| CN1661114A (zh) | 2005-08-31 |
| EP1553415A1 (en) | 2005-07-13 |
| KR100580642B1 (ko) | 2006-05-16 |
| US7195924B2 (en) | 2007-03-27 |
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