JP3974532B2 - ミクロトーム - Google Patents
ミクロトーム Download PDFInfo
- Publication number
- JP3974532B2 JP3974532B2 JP2002564564A JP2002564564A JP3974532B2 JP 3974532 B2 JP3974532 B2 JP 3974532B2 JP 2002564564 A JP2002564564 A JP 2002564564A JP 2002564564 A JP2002564564 A JP 2002564564A JP 3974532 B2 JP3974532 B2 JP 3974532B2
- Authority
- JP
- Japan
- Prior art keywords
- holding device
- microtome
- sample holding
- operating element
- cutting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000005520 cutting process Methods 0.000 claims description 45
- 238000003825 pressing Methods 0.000 claims description 12
- 238000012840 feeding operation Methods 0.000 claims description 10
- 230000009471 action Effects 0.000 claims description 3
- 230000033001 locomotion Effects 0.000 description 36
- 238000000034 method Methods 0.000 description 3
- 230000008901 benefit Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 230000002411 adverse Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 208000003295 carpal tunnel syndrome Diseases 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000003252 repetitive effect Effects 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
- G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
- G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
- G01N2001/065—Drive details
- G01N2001/066—Drive details electric
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
- G01N2001/2873—Cutting or cleaving
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T83/00—Cutting
- Y10T83/061—With manually actuated means to disturb cyclic operation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T83/00—Cutting
- Y10T83/081—With randomly actuated stopping means
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T83/00—Cutting
- Y10T83/141—With means to monitor and control operation [e.g., self-regulating means]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T83/00—Cutting
- Y10T83/647—With means to convey work relative to tool station
- Y10T83/6492—Plural passes of diminishing work piece through tool station
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T83/00—Cutting
- Y10T83/647—With means to convey work relative to tool station
- Y10T83/6492—Plural passes of diminishing work piece through tool station
- Y10T83/6499—Work rectilinearly reciprocated through tool station
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T83/00—Cutting
- Y10T83/869—Means to drive or to guide tool
- Y10T83/8765—Magnet- or solenoid-actuated tool
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10106033A DE10106033A1 (de) | 2001-02-09 | 2001-02-09 | Mikrotom |
| PCT/DE2002/000438 WO2002065095A2 (de) | 2001-02-09 | 2002-02-07 | In zwei steuerungmodi betriebenes mikrotom |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004522154A JP2004522154A (ja) | 2004-07-22 |
| JP2004522154A5 JP2004522154A5 (enExample) | 2005-12-22 |
| JP3974532B2 true JP3974532B2 (ja) | 2007-09-12 |
Family
ID=7673479
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002564564A Expired - Lifetime JP3974532B2 (ja) | 2001-02-09 | 2002-02-07 | ミクロトーム |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7111535B2 (enExample) |
| EP (1) | EP1358462B1 (enExample) |
| JP (1) | JP3974532B2 (enExample) |
| CN (1) | CN1303412C (enExample) |
| AU (1) | AU2002242625A1 (enExample) |
| DE (2) | DE10106033A1 (enExample) |
| RU (1) | RU2300092C2 (enExample) |
| WO (1) | WO2002065095A2 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4953366B2 (ja) * | 2006-02-13 | 2012-06-13 | セイコーインスツル株式会社 | 薄切片作製装置、及び薄切片の作製方法 |
| DE102006031136B3 (de) * | 2006-07-03 | 2007-07-26 | Leica Microsystems Nussloch Gmbh | Kurbelantrieb einer Welle eines Mikrotoms |
| DE102006034879B3 (de) * | 2006-07-25 | 2007-07-12 | Leica Microsystems Nussloch Gmbh | Mikrotom mit einer Hebelanordnung |
| DE102007023457B4 (de) * | 2007-05-19 | 2009-05-20 | Leica Biosystems Nussloch Gmbh | Verfahren zur automatischen Annäherung eines dünn zu schneidenden Präparates an das Messer eines Mikrotoms |
| DE102007026844B4 (de) * | 2007-06-06 | 2011-02-17 | Leica Biosystems Nussloch Gmbh | Vorrichtung zum Bremsen der Welle eines Mikrotoms |
| DE202007018047U1 (de) * | 2007-12-27 | 2008-03-27 | Leica Biosystems Nussloch Gmbh | Mikrotom mit konzentrischen Bedienelementen zum Steuern einer Motoreinheit |
| CN101480801B (zh) * | 2008-01-07 | 2010-08-25 | 致伸科技股份有限公司 | 具有自动模式及手动模式的裁纸装置 |
| AT506233B1 (de) * | 2008-01-18 | 2009-07-15 | Leica Mikrosysteme Gmbh | Mikromanipulator für ein kryomikrotom |
| DE102009006386B4 (de) * | 2009-01-16 | 2011-04-14 | HLT Handel, Logistik und Technologie GmbH | Miktrotom |
| AT507572B1 (de) * | 2009-07-31 | 2010-06-15 | Leica Mikrosysteme Gmbh | Verfahren zur segmentansteuerung einer messerschneide |
| CN201493868U (zh) * | 2009-09-08 | 2010-06-02 | 南京德朔实业有限公司 | 电动剪刀 |
| CN102672743A (zh) * | 2011-03-11 | 2012-09-19 | 湖北孝感阔海医疗科技有限公司 | 高精度切片机自动进样机构 |
| US8869666B2 (en) | 2011-03-24 | 2014-10-28 | Sakura Finetek U.S.A., Inc. | Microtome with surface orientation sensor to sense orientation of surface of sample |
| US9032854B2 (en) | 2011-12-21 | 2015-05-19 | Sakura Finetek U.S.A., Inc. | Reciprocating microtome drive system |
| CN104010860A (zh) | 2011-12-22 | 2014-08-27 | 斯堪尼亚商用车有限公司 | 与确定参考值时的模式选择相关的模块和方法 |
| BR112014012321A2 (pt) | 2011-12-22 | 2017-05-30 | Scania Cv Ab | módulo e método pertencentes a escolha de modo quando determinando valores de referência |
| SE536271C2 (sv) | 2011-12-22 | 2013-07-23 | Scania Cv Ab | Metod och modul för att styra ett fordons hastighet genom simulering |
| EP2794327A4 (en) | 2011-12-22 | 2016-07-13 | Scania Cv Ab | Method and module for determining at least one reference value for a vehicle control system |
| US9193264B2 (en) * | 2011-12-22 | 2015-11-24 | Scania Cv Ab | Method and module for determining of at least one reference value for a vehicle control system |
| RU2598494C2 (ru) | 2011-12-22 | 2016-09-27 | Сканиа Св Аб | Способ и модуль для определения, по меньшей мере, одного опорного значения |
| ITVR20130005A1 (it) * | 2013-01-11 | 2014-07-12 | Diapath S P A | Sistema di regolazione della velocita' di taglio di un microtomo automatico |
| CN104079221A (zh) * | 2013-03-26 | 2014-10-01 | 北京全景多媒体信息系统公司 | 用于互动展品的无限制操作与线性伺服方法 |
| DE102013110776B4 (de) * | 2013-09-30 | 2015-05-13 | Leica Biosystems Nussloch Gmbh | Verfahren und Mikrotom zum Herstellen von Dünnschnitten mit einem Schnittprofilaufzeichnungsmodus |
| CN107374679A (zh) * | 2017-08-16 | 2017-11-24 | 丁伟山 | 肠胃炎内窥镜活检检查装置 |
| CN111417847A (zh) * | 2017-11-30 | 2020-07-14 | 徕卡显微系统(上海)有限公司 | 控制机动切片机 |
| CN109406194B (zh) * | 2017-12-15 | 2024-08-09 | 北京市人工影响天气办公室 | 冰雹切片机 |
| CN110328712B (zh) * | 2019-06-28 | 2020-06-16 | 中国科学院自动化研究所 | 刀刃位置切换方法、装置及包括该装置的超薄切片机 |
| CN111413342B (zh) * | 2020-04-20 | 2021-03-26 | 华中科技大学 | 一种冰冻切片显微成像系统 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3496819A (en) * | 1967-10-26 | 1970-02-24 | Sorvall Inc Ivan | Tissue sectioner |
| DE8100644U1 (de) | 1981-01-14 | 1981-05-14 | Ernst Leitz Wetzlar Gmbh, 6330 Wetzlar | Mikrotomantrieb |
| DE3127266C2 (de) * | 1981-07-10 | 1984-05-30 | Bernhard Dr. 7801 Buchenbach Wolf | Mikrotom |
| DE8129032U1 (de) | 1981-10-03 | 1982-04-29 | Dr. Johannes Heidenhain Gmbh, 8225 Traunreut | Hand-Vorschubvorrichtung elektrischer Art |
| US4691151A (en) * | 1985-01-30 | 1987-09-01 | Cambridge Instruments Gmbh | Microtome feed-motor control |
| DE8910071U1 (de) * | 1989-08-23 | 1989-10-19 | Microm Laborgeräte GmbH, 6902 Sandhausen | Schlitten-Mikrotom |
| AT399226B (de) * | 1990-04-11 | 1995-04-25 | Sitte Hellmuth | Automatische anschneidevorrichtung für mikrotome, insbesondere ultramikrotome |
| AT399227B (de) * | 1990-04-11 | 1995-04-25 | Sitte Hellmuth | Vorrichtung zur steuerung des antriebes sowie des vorschubes eines mikrotoms, insbesondere ultramikrotoms |
| JPH05256745A (ja) * | 1992-03-16 | 1993-10-05 | Feather Safety Razor Co Ltd | ミクロトーム |
| RU2141797C1 (ru) * | 1998-08-03 | 1999-11-27 | Дроздов Константин Александрович | Медицинское устройство для обработки тканей (варианты) |
| DE19911005A1 (de) * | 1999-03-12 | 2000-09-28 | Leica Microsystems | Verfahren zur Steuerung eines Scheibenmikrotoms |
| DE19911173C2 (de) * | 1999-03-12 | 2002-01-31 | Leica Microsystems | Mikrotom mit einem motorischen Zustellantrieb |
| DE19911163C1 (de) * | 1999-03-12 | 2000-07-20 | Leica Microsystems | Mikrotom |
-
2001
- 2001-02-09 DE DE10106033A patent/DE10106033A1/de not_active Ceased
-
2002
- 2002-02-07 CN CNB028047354A patent/CN1303412C/zh not_active Expired - Lifetime
- 2002-02-07 EP EP02708218A patent/EP1358462B1/de not_active Expired - Lifetime
- 2002-02-07 DE DE50204020T patent/DE50204020D1/de not_active Expired - Lifetime
- 2002-02-07 AU AU2002242625A patent/AU2002242625A1/en not_active Abandoned
- 2002-02-07 RU RU2003126577/12A patent/RU2300092C2/ru not_active IP Right Cessation
- 2002-02-07 WO PCT/DE2002/000438 patent/WO2002065095A2/de not_active Ceased
- 2002-02-07 US US10/470,110 patent/US7111535B2/en not_active Expired - Lifetime
- 2002-02-07 JP JP2002564564A patent/JP3974532B2/ja not_active Expired - Lifetime
-
2005
- 2005-10-21 US US11/255,907 patent/US7044038B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004522154A (ja) | 2004-07-22 |
| RU2003126577A (ru) | 2005-01-27 |
| EP1358462A2 (de) | 2003-11-05 |
| AU2002242625A1 (en) | 2002-08-28 |
| US7111535B2 (en) | 2006-09-26 |
| US20060037454A1 (en) | 2006-02-23 |
| DE10106033A1 (de) | 2002-08-29 |
| US20040149106A1 (en) | 2004-08-05 |
| US7044038B2 (en) | 2006-05-16 |
| RU2300092C2 (ru) | 2007-05-27 |
| WO2002065095A3 (de) | 2003-01-23 |
| DE50204020D1 (de) | 2005-09-29 |
| CN1630813A (zh) | 2005-06-22 |
| CN1303412C (zh) | 2007-03-07 |
| WO2002065095A2 (de) | 2002-08-22 |
| EP1358462B1 (de) | 2005-08-24 |
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