JP3819032B2 - 組織およびその他のランダム媒体における蛍光寿命に基づく撮像および分光分析 - Google Patents
組織およびその他のランダム媒体における蛍光寿命に基づく撮像および分光分析 Download PDFInfo
- Publication number
- JP3819032B2 JP3819032B2 JP51047197A JP51047197A JP3819032B2 JP 3819032 B2 JP3819032 B2 JP 3819032B2 JP 51047197 A JP51047197 A JP 51047197A JP 51047197 A JP51047197 A JP 51047197A JP 3819032 B2 JP3819032 B2 JP 3819032B2
- Authority
- JP
- Japan
- Prior art keywords
- fluorescence
- tissue
- light
- emission
- excitation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
- G01J3/4406—Fluorescence spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/4795—Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Spectroscopy & Molecular Physics (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Optics & Photonics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US274695P | 1995-08-24 | 1995-08-24 | |
| US60/002,746 | 1995-08-24 | ||
| PCT/US1996/013658 WO1997008538A1 (en) | 1995-08-24 | 1996-08-23 | Fluorescence lifetime-based imaging and spectroscopy in tissues and other random media |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2000500228A JP2000500228A (ja) | 2000-01-11 |
| JP2000500228A5 JP2000500228A5 (enExample) | 2004-09-09 |
| JP3819032B2 true JP3819032B2 (ja) | 2006-09-06 |
Family
ID=21702295
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51047197A Expired - Lifetime JP3819032B2 (ja) | 1995-08-24 | 1996-08-23 | 組織およびその他のランダム媒体における蛍光寿命に基づく撮像および分光分析 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5865754A (enExample) |
| EP (1) | EP0846262A4 (enExample) |
| JP (1) | JP3819032B2 (enExample) |
| CN (1) | CN1200174A (enExample) |
| AU (1) | AU1130797A (enExample) |
| CA (1) | CA2230228C (enExample) |
| MX (1) | MX9801351A (enExample) |
| NO (1) | NO980750L (enExample) |
| WO (1) | WO1997008538A1 (enExample) |
Families Citing this family (267)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5353799A (en) * | 1991-01-22 | 1994-10-11 | Non Invasive Technology, Inc. | Examination of subjects using photon migration with high directionality techniques |
| US6304771B1 (en) * | 1993-10-29 | 2001-10-16 | The Trustees Of The University Of Pennsylvania | Systems and methods for imaging fluorophores |
| US5919140A (en) * | 1995-02-21 | 1999-07-06 | Massachusetts Institute Of Technology | Optical imaging using time gated scattered light |
| US7328059B2 (en) | 1996-08-23 | 2008-02-05 | The Texas A & M University System | Imaging of light scattering tissues with fluorescent contrast agents |
| US6766183B2 (en) | 1995-11-22 | 2004-07-20 | Medtronic Minimed, Inc. | Long wave fluorophore sensor compounds and other fluorescent sensor compounds in polymers |
| US6571119B2 (en) | 1996-03-06 | 2003-05-27 | Fuji Photo Film Co., Ltd. | Fluorescence detecting apparatus |
| JP3796635B2 (ja) * | 1996-03-06 | 2006-07-12 | 富士写真フイルム株式会社 | 蛍光検出装置 |
| US6525862B2 (en) * | 1996-10-30 | 2003-02-25 | Photogen, Inc. | Methods and apparatus for optical imaging |
| EP0983501A4 (en) | 1996-11-08 | 2000-03-08 | Purdue Research Foundation | PARTICLE ANALYSIS SYSTEM AND METHOD |
| US5952664A (en) * | 1997-01-17 | 1999-09-14 | Imaging Diagnostic Systems, Inc. | Laser imaging apparatus using biomedical markers that bind to cancer cells |
| US5963658A (en) * | 1997-01-27 | 1999-10-05 | University Of North Carolina | Method and apparatus for detecting an abnormality within a host medium |
| US7865230B1 (en) | 1997-02-07 | 2011-01-04 | Texas A&M University System | Method and system for detecting sentinel lymph nodes |
| US6208886B1 (en) * | 1997-04-04 | 2001-03-27 | The Research Foundation Of City College Of New York | Non-linear optical tomography of turbid media |
| US6124597A (en) * | 1997-07-07 | 2000-09-26 | Cedars-Sinai Medical Center | Method and devices for laser induced fluorescence attenuation spectroscopy |
| US6422994B1 (en) * | 1997-09-24 | 2002-07-23 | Olympus Optical Co., Ltd. | Fluorescent diagnostic system and method providing color discrimination enhancement |
| WO1999037204A1 (en) * | 1998-01-26 | 1999-07-29 | Massachusetts Institute Of Technology | Fluorescence imaging endoscope |
| US6592847B1 (en) * | 1998-05-14 | 2003-07-15 | The General Hospital Corporation | Intramolecularly-quenched near infrared flourescent probes |
| US6059820A (en) | 1998-10-16 | 2000-05-09 | Paradigm Medical Corporation | Tissue cooling rod for laser surgery |
| US7107116B2 (en) * | 1999-03-29 | 2006-09-12 | Genex Technologies, Inc. | Diffuse optical tomography system and method of use |
| CN1325022C (zh) * | 1999-04-01 | 2007-07-11 | 成象诊断系统公司 | 使用约束肿瘤细胞的生化标记的激光成像装置 |
| US6167297A (en) | 1999-05-05 | 2000-12-26 | Benaron; David A. | Detecting, localizing, and targeting internal sites in vivo using optical contrast agents |
| CA2384813C (en) * | 1999-09-14 | 2014-01-21 | Randall L. Barbour | Method and system for imaging the dynamics of scattering medium |
| US6795195B1 (en) * | 1999-09-14 | 2004-09-21 | Research Foundation Of State University Of New York | System and method for tomographic imaging of dynamic properties of a scattering medium |
| US20050182434A1 (en) | 2000-08-11 | 2005-08-18 | National Research Council Of Canada | Method and apparatus for performing intra-operative angiography |
| US6915154B1 (en) | 1999-09-24 | 2005-07-05 | National Research Council Of Canada | Method and apparatus for performing intra-operative angiography |
| US7054002B1 (en) | 1999-10-08 | 2006-05-30 | The Texas A&M University System | Characterization of luminescence in a scattering medium |
| US7006676B1 (en) | 2000-01-21 | 2006-02-28 | Medical Optical Imaging, Inc. | Method and apparatus for detecting an abnormality within a host medium utilizing frequency-swept modulation diffusion tomography |
| US20010032053A1 (en) * | 2000-01-24 | 2001-10-18 | Hielscher Andreas H. | Imaging of a scattering medium using the equation of radiative transfer |
| CA2400305A1 (en) * | 2000-02-18 | 2001-08-23 | Argose,Inc. | Generation of spatially-averaged excitation-emission map in heterogeneous tissue |
| JP2003535330A (ja) * | 2000-06-02 | 2003-11-25 | メディコメトリクス アンパーツゼルスカブ | 生物試料の分類のための方法及びシステム |
| US6748259B1 (en) * | 2000-06-15 | 2004-06-08 | Spectros Corporation | Optical imaging of induced signals in vivo under ambient light conditions |
| US6801648B2 (en) * | 2000-08-04 | 2004-10-05 | Xuefeng Cheng | Optical imaging system with symmetric optical probe |
| US6587703B2 (en) | 2000-09-18 | 2003-07-01 | Photonify Technologies, Inc. | System and method for measuring absolute oxygen saturation |
| US6597931B1 (en) | 2000-09-18 | 2003-07-22 | Photonify Technologies, Inc. | System and method for absolute oxygen saturation |
| US6516209B2 (en) | 2000-08-04 | 2003-02-04 | Photonify Technologies, Inc. | Self-calibrating optical imaging system |
| CA2424894A1 (en) | 2000-10-06 | 2002-04-11 | Victor X. D. Yang | Multi-spectral fluorescence imaging and spectroscopy device |
| WO2002036015A1 (en) * | 2000-10-30 | 2002-05-10 | The General Hospital Corporation | Optical methods and systems for tissue analysis |
| US9295391B1 (en) | 2000-11-10 | 2016-03-29 | The General Hospital Corporation | Spectrally encoded miniature endoscopic imaging probe |
| US6615063B1 (en) * | 2000-11-27 | 2003-09-02 | The General Hospital Corporation | Fluorescence-mediated molecular tomography |
| US7383076B2 (en) * | 2000-11-27 | 2008-06-03 | The General Hospital Corporation | Fluorescence-mediated molecular tomography |
| US6826424B1 (en) * | 2000-12-19 | 2004-11-30 | Haishan Zeng | Methods and apparatus for fluorescence and reflectance imaging and spectroscopy and for contemporaneous measurements of electromagnetic radiation with multiple measuring devices |
| US20030044353A1 (en) * | 2001-01-05 | 2003-03-06 | Ralph Weissleder | Activatable imaging probes |
| US6609015B2 (en) * | 2001-01-18 | 2003-08-19 | Koninklijke Philips Electronics N.V. | Analysis of a composition |
| AU2002251944A1 (en) * | 2001-02-15 | 2002-09-04 | Medtronic Minimed, Inc. | Polymers functionalized with fluorescent boronate motifs |
| NO325061B1 (no) * | 2001-03-06 | 2008-01-28 | Photosense As | Fremgangsmate og arrangement for bestemmelse av den optiske egenskap av et multisjiktvev |
| WO2002082055A2 (en) * | 2001-04-03 | 2002-10-17 | The Texas A & M University System | Method for characterising particles in suspension from frequency domain photon migration measurements |
| US6930777B1 (en) | 2001-04-03 | 2005-08-16 | The Texas A&M University System | Method for characterizing particles in suspension from frequency domain photon migration measurements |
| US9897538B2 (en) * | 2001-04-30 | 2018-02-20 | The General Hospital Corporation | Method and apparatus for improving image clarity and sensitivity in optical coherence tomography using dynamic feedback to control focal properties and coherence gating |
| GB2408797B (en) | 2001-05-01 | 2006-09-20 | Gen Hospital Corp | Method and apparatus for determination of atherosclerotic plaque type by measurement of tissue optical properties |
| ATE336717T1 (de) * | 2001-05-17 | 2006-09-15 | Xenogen Corp | Verfahren und vorrichtung zur feststellung von zieltiefe, helligkeit und grösse in einer körperregion |
| US7116354B2 (en) | 2001-06-20 | 2006-10-03 | Xenogen Corporation | Absolute intensity determination for a light source in low level light imaging systems |
| US7298415B2 (en) * | 2001-07-13 | 2007-11-20 | Xenogen Corporation | Structured light imaging apparatus |
| US7045361B2 (en) | 2001-09-12 | 2006-05-16 | Medtronic Minimed, Inc. | Analyte sensing via acridine-based boronate biosensors |
| US6980299B1 (en) * | 2001-10-16 | 2005-12-27 | General Hospital Corporation | Systems and methods for imaging a sample |
| US20030216719A1 (en) * | 2001-12-12 | 2003-11-20 | Len Debenedictis | Method and apparatus for treating skin using patterns of optical energy |
| US20040082940A1 (en) * | 2002-10-22 | 2004-04-29 | Michael Black | Dermatological apparatus and method |
| US20030109860A1 (en) * | 2001-12-12 | 2003-06-12 | Michael Black | Multiple laser treatment |
| US20030109787A1 (en) * | 2001-12-12 | 2003-06-12 | Michael Black | Multiple laser diagnostics |
| ATE503982T1 (de) * | 2002-01-11 | 2011-04-15 | Gen Hospital Corp | Vorrichtung zur oct bildaufnahme mit axialem linienfokus für verbesserte auflösung und tiefenschärfe |
| US7355716B2 (en) * | 2002-01-24 | 2008-04-08 | The General Hospital Corporation | Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands |
| US7629573B2 (en) * | 2002-02-06 | 2009-12-08 | Xenogen Corporation | Tissue phantom calibration device for low level light imaging systems |
| US7649185B2 (en) * | 2002-02-06 | 2010-01-19 | Xenogen Corporation | Fluorescent phantom device |
| US20110201924A1 (en) * | 2002-04-30 | 2011-08-18 | The General Hospital Corporation | Method and Apparatus for Improving Image Clarity and Sensitivity in Optical Tomography Using Dynamic Feedback to Control Focal Properties and Coherence Gating |
| EP2410315B1 (en) | 2002-06-04 | 2020-04-01 | Visen Medical, Inc. | Imaging volumes with arbitrary geometries in contact and non-contact tomography |
| US7616985B2 (en) * | 2002-07-16 | 2009-11-10 | Xenogen Corporation | Method and apparatus for 3-D imaging of internal light sources |
| US7599731B2 (en) * | 2002-07-16 | 2009-10-06 | Xenogen Corporation | Fluorescent light tomography |
| DK2270816T3 (da) * | 2002-07-31 | 2014-08-25 | Premium Genetics Uk Ltd | System og fremgangsmåde til sortering af materialer under anvendelse af holografisk laserstyring |
| DE10255013B4 (de) * | 2002-11-25 | 2004-12-09 | Siemens Ag | Verfahren und Vorrichtung zur Lokalisierung von Licht emittierenden Bereichen |
| US7582882B2 (en) * | 2003-01-23 | 2009-09-01 | Horiba Jobin Yvon, Inc. | Solid state multi frequency fluorometric measurements system and method |
| US7297962B2 (en) * | 2003-01-23 | 2007-11-20 | Horiba Jobin Yvon, Inc. | Method for performing spacially coordinated high speed fluorometric measurements |
| US7317194B2 (en) * | 2003-01-23 | 2008-01-08 | Horiba Jobin Yuon, Inc. | Microscope for performing multiple frequency fluorometric measurements |
| US7761139B2 (en) * | 2003-01-24 | 2010-07-20 | The General Hospital Corporation | System and method for identifying tissue using low-coherence interferometry |
| US8054468B2 (en) | 2003-01-24 | 2011-11-08 | The General Hospital Corporation | Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands |
| WO2004072906A1 (en) * | 2003-02-05 | 2004-08-26 | The General Hospital Corporation | Method and system for free space optical tomography of diffuse media |
| DE602004006396T2 (de) * | 2003-03-18 | 2008-01-10 | Koninklijke Philips Electronics N.V. | Analyse einer zusammenstellung mit beobachtung |
| WO2004086947A2 (en) * | 2003-03-27 | 2004-10-14 | The General Hospital Corporation | Method and apparatus for dermatological treatment and fractional skin resurfacing |
| CA2519937C (en) | 2003-03-31 | 2012-11-20 | Guillermo J. Tearney | Speckle reduction in optical coherence tomography by path length encoded angular compounding |
| CA2521304A1 (en) * | 2003-04-04 | 2004-10-21 | Lumidigm, Inc. | Multispectral biometric sensor |
| US7181219B2 (en) | 2003-05-22 | 2007-02-20 | Lucent Technologies Inc. | Wireless handover using anchor termination |
| EP2290337B1 (en) | 2003-06-06 | 2018-12-12 | The General Hospital Corporation | Wavelength tuning laser |
| CA2533621C (en) * | 2003-06-20 | 2013-12-10 | The Texas A & M University System | Method and system for near-infrared fluorescence contrast-enhanced imaging with area illumination and area detection |
| WO2005002425A2 (en) * | 2003-07-02 | 2005-01-13 | U.S. Government As Represented By The Secretary Of The Army | Wearable tissue viability diagnostic unit |
| JP2007531544A (ja) * | 2003-07-11 | 2007-11-08 | リライアント・テクノロジーズ・インコーポレイテッド | 皮膚の分画光治療のための方法と装置 |
| US7920908B2 (en) | 2003-10-16 | 2011-04-05 | David Hattery | Multispectral imaging for quantitative contrast of functional and structural features of layers inside optically dense media such as tissue |
| US7733497B2 (en) | 2003-10-27 | 2010-06-08 | The General Hospital Corporation | Method and apparatus for performing optical imaging using frequency-domain interferometry |
| WO2005054780A1 (en) * | 2003-11-28 | 2005-06-16 | The General Hospital Corporation | Method and apparatus for three-dimensional spectrally encoded imaging |
| WO2005065090A2 (en) * | 2003-12-30 | 2005-07-21 | The Mitre Corporation | Techniques for building-scale electrostatic tomography |
| US20050165427A1 (en) * | 2004-01-22 | 2005-07-28 | Jahns Scott E. | Vessel sealing devices |
| US20070010868A1 (en) * | 2004-04-19 | 2007-01-11 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Lumenally-active device |
| US9801527B2 (en) * | 2004-04-19 | 2017-10-31 | Gearbox, Llc | Lumen-traveling biological interface device |
| US8019413B2 (en) * | 2007-03-19 | 2011-09-13 | The Invention Science Fund I, Llc | Lumen-traveling biological interface device and method of use |
| US8353896B2 (en) * | 2004-04-19 | 2013-01-15 | The Invention Science Fund I, Llc | Controllable release nasal system |
| US9011329B2 (en) | 2004-04-19 | 2015-04-21 | Searete Llc | Lumenally-active device |
| US8092549B2 (en) * | 2004-09-24 | 2012-01-10 | The Invention Science Fund I, Llc | Ciliated stent-like-system |
| US8361013B2 (en) * | 2004-04-19 | 2013-01-29 | The Invention Science Fund I, Llc | Telescoping perfusion management system |
| US8337482B2 (en) * | 2004-04-19 | 2012-12-25 | The Invention Science Fund I, Llc | System for perfusion management |
| US20050234440A1 (en) * | 2004-04-19 | 2005-10-20 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | System with a sensor for perfusion management |
| US20070244520A1 (en) * | 2004-04-19 | 2007-10-18 | Searete Llc | Lumen-traveling biological interface device and method of use |
| DE102004024494B4 (de) * | 2004-05-16 | 2019-10-17 | Dürr Dental SE | Medizinische Kamera |
| JP4750786B2 (ja) | 2004-05-29 | 2011-08-17 | ザ ジェネラル ホスピタル コーポレイション | 光コヒーレンストモグラフィ(oct)イメージングにおける屈折層を用いた色分散補償プロセス、システム及びソフトウェア構成 |
| US7413572B2 (en) * | 2004-06-14 | 2008-08-19 | Reliant Technologies, Inc. | Adaptive control of optical pulses for laser medicine |
| AU2005270037B2 (en) | 2004-07-02 | 2012-02-09 | The General Hospital Corporation | Endoscopic imaging probe comprising dual clad fibre |
| US20060217788A1 (en) * | 2004-07-09 | 2006-09-28 | Herron G S | Method of using laser induced injury to activate topical prodrugs |
| EP1782020B1 (en) | 2004-08-06 | 2012-10-03 | The General Hospital Corporation | Process, system and software arrangement for determining at least one location in a sample using an optical coherence tomography |
| JP5334415B2 (ja) * | 2004-08-24 | 2013-11-06 | ザ ジェネラル ホスピタル コーポレイション | 試料の機械的歪み及び弾性的性質を測定するプロセス、システム及びソフトウェア |
| KR20070058523A (ko) | 2004-08-24 | 2007-06-08 | 더 제너럴 하스피탈 코포레이션 | 혈관절편 영상화 방법 및 장치 |
| US7365859B2 (en) * | 2004-09-10 | 2008-04-29 | The General Hospital Corporation | System and method for optical coherence imaging |
| EP2329759B1 (en) * | 2004-09-29 | 2014-03-12 | The General Hospital Corporation | System and method for optical coherence imaging |
| US20060122584A1 (en) * | 2004-10-27 | 2006-06-08 | Bommannan D B | Apparatus and method to treat heart disease using lasers to form microchannels |
| EP1819270B1 (en) * | 2004-10-29 | 2012-12-19 | The General Hospital Corporation | Polarization-sensitive optical coherence tomography |
| WO2006050453A1 (en) * | 2004-11-02 | 2006-05-11 | The General Hospital Corporation | Fiber-optic rotational device, optical system and method for imaging a sample |
| US7995210B2 (en) * | 2004-11-24 | 2011-08-09 | The General Hospital Corporation | Devices and arrangements for performing coherence range imaging using a common path interferometer |
| US8922781B2 (en) * | 2004-11-29 | 2014-12-30 | The General Hospital Corporation | Arrangements, devices, endoscopes, catheters and methods for performing optical imaging by simultaneously illuminating and detecting multiple points on a sample |
| US7966051B2 (en) * | 2005-01-11 | 2011-06-21 | Olympus Corporation | Fluorescent agent concentration measuring apparatus, dose control apparatus, administration system, fluorescent agent concentration measuring method, and dose control method |
| US7729750B2 (en) * | 2005-01-20 | 2010-06-01 | The Regents Of The University Of California | Method and apparatus for high resolution spatially modulated fluorescence imaging and tomography |
| KR20080013919A (ko) * | 2005-04-22 | 2008-02-13 | 더 제너럴 하스피탈 코포레이션 | 스펙트럼 도메인 편광 민감형 광간섭 단층촬영을 제공할 수있는 장치, 시스템 및 방법 |
| US20060239921A1 (en) | 2005-04-26 | 2006-10-26 | Novadaq Technologies Inc. | Real time vascular imaging during solid organ transplant |
| EP1875436B1 (en) | 2005-04-28 | 2009-12-09 | The General Hospital Corporation | Evaluation of image features of an anatomical structure in optical coherence tomography images |
| US8044996B2 (en) * | 2005-05-11 | 2011-10-25 | Xenogen Corporation | Surface construction using combined photographic and structured light information |
| EP1886121A1 (en) * | 2005-05-13 | 2008-02-13 | The General Hospital Corporation | Arrangements, systems and methods capable of providing spectral-domain optical coherence reflectometry for a sensitive detection of chemical and biological sample |
| US7859679B2 (en) * | 2005-05-31 | 2010-12-28 | The General Hospital Corporation | System, method and arrangement which can use spectral encoding heterodyne interferometry techniques for imaging |
| WO2006130802A2 (en) * | 2005-06-01 | 2006-12-07 | The General Hospital Corporation | Apparatus, method and system for performing phase-resolved optical frequency domain imaging |
| ES2354287T3 (es) * | 2005-08-09 | 2011-03-11 | The General Hospital Corporation | Aparato y método para realizar una desmodulación en cuadratura por polarización en tomografía de coherencia óptica. |
| WO2007022220A2 (en) * | 2005-08-16 | 2007-02-22 | The General Hospital Corporation | Arrangements and methods for imaging in vessels |
| US20070049996A1 (en) * | 2005-08-29 | 2007-03-01 | Reliant Technologies, Inc. | Monitoring Method and Apparatus for Fractional Photo-Therapy Treatment |
| WO2007027962A2 (en) * | 2005-08-29 | 2007-03-08 | Reliant Technologies, Inc. | Method and apparatus for monitoring and controlling thermally induced tissue treatment |
| US20070122344A1 (en) | 2005-09-02 | 2007-05-31 | University Of Rochester Medical Center Office Of Technology Transfer | Intraoperative determination of nerve location |
| CN101304682B (zh) * | 2005-09-29 | 2012-05-30 | 通用医疗公司 | 用于提供一个或多个生物结构的多模态显微成像的装置和方法 |
| US7889348B2 (en) * | 2005-10-14 | 2011-02-15 | The General Hospital Corporation | Arrangements and methods for facilitating photoluminescence imaging |
| EP1945794A2 (en) * | 2005-11-09 | 2008-07-23 | Chemimage Corporation | System and method for cytological analysis by raman spectroscopic imaging |
| EP1948008A2 (en) * | 2005-11-10 | 2008-07-30 | Philips Intellectual Property & Standards GmbH | Absorption and scattering map reconstruction for optical fluorescence tomography |
| JP2009516847A (ja) * | 2005-11-23 | 2009-04-23 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 混濁媒体の内部を画像化する装置 |
| JP2009517115A (ja) * | 2005-11-25 | 2009-04-30 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 光学蛍光トモグラフィ |
| US7796270B2 (en) * | 2006-01-10 | 2010-09-14 | The General Hospital Corporation | Systems and methods for generating data based on one or more spectrally-encoded endoscopy techniques |
| US20070223006A1 (en) * | 2006-01-19 | 2007-09-27 | The General Hospital Corporation | Systems and methods for performing rapid fluorescence lifetime, excitation and emission spectral measurements |
| US8145018B2 (en) * | 2006-01-19 | 2012-03-27 | The General Hospital Corporation | Apparatus for obtaining information for a structure using spectrally-encoded endoscopy techniques and methods for producing one or more optical arrangements |
| WO2007084995A2 (en) * | 2006-01-19 | 2007-07-26 | The General Hospital Corporation | Methods and systems for optical imaging of epithelial luminal organs by beam scanning thereof |
| WO2007084959A1 (en) * | 2006-01-20 | 2007-07-26 | The General Hospital Corporation | Systems and methods for providing mirror tunnel microscopy |
| JP2009524066A (ja) * | 2006-01-20 | 2009-06-25 | ザ ジェネラル ホスピタル コーポレイション | 波面変調を使用してスペックル低減を提供する光学的干渉断層撮影法のシステム、構成、及びプロセス |
| US20070171433A1 (en) * | 2006-01-20 | 2007-07-26 | The General Hospital Corporation | Systems and processes for providing endogenous molecular imaging with mid-infrared light |
| US10426548B2 (en) * | 2006-02-01 | 2019-10-01 | The General Hosppital Corporation | Methods and systems for providing electromagnetic radiation to at least one portion of a sample using conformal laser therapy procedures |
| EP1986562B1 (en) * | 2006-02-01 | 2015-04-08 | The General Hospital Corporation | Apparatus for controlling at least one of at least two sections of at least one fiber |
| US7538859B2 (en) * | 2006-02-01 | 2009-05-26 | The General Hospital Corporation | Methods and systems for monitoring and obtaining information of at least one portion of a sample using conformal laser therapy procedures, and providing electromagnetic radiation thereto |
| EP3143926B1 (en) | 2006-02-08 | 2020-07-01 | The General Hospital Corporation | Methods, arrangements and systems for obtaining information associated with an anatomical sample using optical microscopy |
| JP2009527770A (ja) * | 2006-02-24 | 2009-07-30 | ザ ジェネラル ホスピタル コーポレイション | 角度分解型のフーリエドメイン光干渉断層撮影法を遂行する方法及びシステム |
| US20070208400A1 (en) * | 2006-03-01 | 2007-09-06 | The General Hospital Corporation | System and method for providing cell specific laser therapy of atherosclerotic plaques by targeting light absorbers in macrophages |
| US20070239033A1 (en) * | 2006-03-17 | 2007-10-11 | The General Hospital Corporation | Arrangement, method and computer-accessible medium for identifying characteristics of at least a portion of a blood vessel contained within a tissue using spectral domain low coherence interferometry |
| EP2004041B1 (en) * | 2006-04-05 | 2013-11-06 | The General Hospital Corporation | Methods, arrangements and systems for polarization-sensitive optical frequency domain imaging of a sample |
| US20080058786A1 (en) * | 2006-04-12 | 2008-03-06 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Autofluorescent imaging and target ablation |
| US20120035437A1 (en) | 2006-04-12 | 2012-02-09 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Navigation of a lumen traveling device toward a target |
| US20080058788A1 (en) * | 2006-04-12 | 2008-03-06 | Searete Llc., A Limited Liability Corporation Of The State Of Delaware | Autofluorescent imaging and target ablation |
| US8755866B2 (en) * | 2006-05-03 | 2014-06-17 | Covidien Lp | Method and apparatus for lymph node mapping |
| WO2007133961A2 (en) | 2006-05-10 | 2007-11-22 | The General Hospital Corporation | Processes, arrangements and systems for providing frequency domain imaging of a sample |
| WO2007133964A2 (en) * | 2006-05-12 | 2007-11-22 | The General Hospital Corporation | Processes, arrangements and systems for providing a fiber layer thickness map based on optical coherence tomography images |
| RU2454921C2 (ru) * | 2006-07-07 | 2012-07-10 | Конинклейке Филипс Электроникс Н.В. | Оптическая отображающая система и способ |
| WO2008016927A2 (en) * | 2006-08-01 | 2008-02-07 | The General Hospital Corporation | Systems and methods for receiving and/or analyzing information associated with electro-magnetic radiation |
| JP2008043396A (ja) * | 2006-08-11 | 2008-02-28 | Olympus Corp | 内視鏡システム |
| US20080050316A1 (en) * | 2006-08-24 | 2008-02-28 | Baylor College Of Medicine | Molecular imaging of epithelial cells in lymph |
| WO2008025005A2 (en) * | 2006-08-24 | 2008-02-28 | Baylor College Of Medicine | Method of measuring propulsion in lymphatic structures |
| US10335038B2 (en) | 2006-08-24 | 2019-07-02 | Xenogen Corporation | Spectral unmixing for in-vivo imaging |
| US10775308B2 (en) * | 2006-08-24 | 2020-09-15 | Xenogen Corporation | Apparatus and methods for determining optical tissue properties |
| WO2008024948A2 (en) * | 2006-08-25 | 2008-02-28 | The General Hospital Corporation | Apparatus and methods for enhancing optical coherence tomography imaging using volumetric filtering techniques |
| US20080058782A1 (en) * | 2006-08-29 | 2008-03-06 | Reliant Technologies, Inc. | Method and apparatus for monitoring and controlling density of fractional tissue treatments |
| US20110042580A1 (en) * | 2006-09-06 | 2011-02-24 | University Health Network | Fluorescence quantification and image acquisition in highly turbid media |
| US20080161744A1 (en) | 2006-09-07 | 2008-07-03 | University Of Rochester Medical Center | Pre-And Intra-Operative Localization of Penile Sentinel Nodes |
| US20080287808A1 (en) * | 2006-09-12 | 2008-11-20 | The General Hospital Corporation | Apparatus, probe and method for providing depth assessment in an anatomical structure |
| WO2008049118A2 (en) | 2006-10-19 | 2008-04-24 | The General Hospital Corporation | Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample and effecting such portion(s) |
| US8155730B2 (en) | 2006-10-24 | 2012-04-10 | The Research Foundation Of State University Of New York | Composition, method, system, and kit for optical electrophysiology |
| WO2008052189A2 (en) * | 2006-10-26 | 2008-05-02 | Reliant Technologies, Inc. | Micropore delivery of active substances |
| JP2008148791A (ja) * | 2006-12-14 | 2008-07-03 | Olympus Corp | 内視鏡システム |
| US20080206804A1 (en) * | 2007-01-19 | 2008-08-28 | The General Hospital Corporation | Arrangements and methods for multidimensional multiplexed luminescence imaging and diagnosis |
| EP2662674A3 (en) * | 2007-01-19 | 2014-06-25 | The General Hospital Corporation | Rotating disk reflection for fast wavelength scanning of dispersed broadbend light |
| US7911621B2 (en) | 2007-01-19 | 2011-03-22 | The General Hospital Corporation | Apparatus and method for controlling ranging depth in optical frequency domain imaging |
| WO2008116010A1 (en) * | 2007-03-19 | 2008-09-25 | The General Hospital Corporation | System and method for providing noninvasive diagnosis of compartment syndrome exemplary laser speckle imaging procedure |
| WO2008115965A1 (en) * | 2007-03-19 | 2008-09-25 | The General Hospital Corporation | Apparatus and method for providing a noninvasive diagnosis of internal bleeding |
| EP2132840A2 (en) * | 2007-03-23 | 2009-12-16 | The General Hospital Corporation | Methods, arrangements and apparatus for utlizing a wavelength-swept laser using angular scanning and dispersion procedures |
| US10534129B2 (en) * | 2007-03-30 | 2020-01-14 | The General Hospital Corporation | System and method providing intracoronary laser speckle imaging for the detection of vulnerable plaque |
| US8045177B2 (en) * | 2007-04-17 | 2011-10-25 | The General Hospital Corporation | Apparatus and methods for measuring vibrations using spectrally-encoded endoscopy |
| WO2008132522A1 (en) | 2007-04-25 | 2008-11-06 | Ruder Boscovic Institute | Method for real time tumour visualisation and demarcation by means of photodynamic diagnosis |
| WO2008137637A2 (en) * | 2007-05-04 | 2008-11-13 | The General Hospital Corporation | Methods, arrangements and systems for obtaining information associated with a sample using brillouin microscopy |
| US7692160B2 (en) * | 2007-05-31 | 2010-04-06 | General Electric Company | Method and system of optical imaging for target detection in a scattering medium |
| US7812945B2 (en) * | 2007-06-15 | 2010-10-12 | Art Advanced Research Technologies Inc. | Fluorescence tomography using line-by-line forward model |
| WO2009018456A2 (en) * | 2007-07-31 | 2009-02-05 | The General Hospital Corporation | Systems and methods for providing beam scan patterns for high speed doppler optical frequency domain imaging |
| EP2191254B1 (en) * | 2007-08-31 | 2017-07-19 | The General Hospital Corporation | System and method for self-interference fluorescence microscopy, and computer-accessible medium associated therewith |
| US20100305436A1 (en) * | 2007-09-14 | 2010-12-02 | Light Sciences Oncology , Inc. | Systems, devices, and methods for photoactive assisted resection |
| US20090073439A1 (en) * | 2007-09-15 | 2009-03-19 | The General Hospital Corporation | Apparatus, computer-accessible medium and method for measuring chemical and/or molecular compositions of coronary atherosclerotic plaques in anatomical structures |
| JP2011500173A (ja) * | 2007-10-12 | 2011-01-06 | ザ ジェネラル ホスピタル コーポレイション | 管腔解剖構造の光学イメージングのためのシステムおよびプロセス |
| WO2009059034A1 (en) * | 2007-10-30 | 2009-05-07 | The General Hospital Corporation | System and method for cladding mode detection |
| US20090225324A1 (en) * | 2008-01-17 | 2009-09-10 | The General Hospital Corporation | Apparatus for providing endoscopic high-speed optical coherence tomography |
| EP3320923B1 (en) | 2008-01-18 | 2022-04-06 | Visen Medical, Inc. | Fluorescent imaging agents |
| US8406860B2 (en) | 2008-01-25 | 2013-03-26 | Novadaq Technologies Inc. | Method for evaluating blush in myocardial tissue |
| US9332942B2 (en) * | 2008-01-28 | 2016-05-10 | The General Hospital Corporation | Systems, processes and computer-accessible medium for providing hybrid flourescence and optical coherence tomography imaging |
| US11123047B2 (en) | 2008-01-28 | 2021-09-21 | The General Hospital Corporation | Hybrid systems and methods for multi-modal acquisition of intravascular imaging data and counteracting the effects of signal absorption in blood |
| US20090240138A1 (en) * | 2008-03-18 | 2009-09-24 | Steven Yi | Diffuse Optical Tomography System and Method of Use |
| US20090240139A1 (en) * | 2008-03-18 | 2009-09-24 | Steven Yi | Diffuse Optical Tomography System and Method of Use |
| US20090236541A1 (en) * | 2008-03-24 | 2009-09-24 | General Electric Company | System and Methods for Optical Imaging |
| WO2009120228A1 (en) * | 2008-03-24 | 2009-10-01 | General Electric Company | Image processing systems and methods for surgical applications |
| CN101980656B (zh) * | 2008-03-27 | 2013-12-04 | 皇家飞利浦电子股份有限公司 | 用于重构混浊介质内部的荧光图像的方法以及用于对混浊介质内部成像的设备 |
| US10219742B2 (en) | 2008-04-14 | 2019-03-05 | Novadaq Technologies ULC | Locating and analyzing perforator flaps for plastic and reconstructive surgery |
| EP2285421B1 (en) | 2008-05-02 | 2018-04-11 | Novadaq Technologies ULC | Methods for production and use of substance-loaded erythrocytes for observation and treatment of microvascular hemodynamics |
| US8593619B2 (en) | 2008-05-07 | 2013-11-26 | The General Hospital Corporation | System, method and computer-accessible medium for tracking vessel motion during three-dimensional coronary artery microscopy |
| ES2989708T3 (es) | 2008-05-20 | 2024-11-27 | Univ Health Network | Dispositivo y método para formación de imágenes y supervisión por fluorescencia |
| JP4575474B2 (ja) * | 2008-06-11 | 2010-11-04 | 国立大学法人東京工業大学 | 生体組織識別装置および方法 |
| WO2009155536A2 (en) * | 2008-06-20 | 2009-12-23 | The General Hospital Corporation | Fused fiber optic coupler arrangement and method for use thereof |
| US9254089B2 (en) * | 2008-07-14 | 2016-02-09 | The General Hospital Corporation | Apparatus and methods for facilitating at least partial overlap of dispersed ration on at least one sample |
| US20110200525A1 (en) * | 2008-10-09 | 2011-08-18 | Patz Jr Edward F | Vhh antibody fragments for use in the detection and treatment of cancer |
| WO2010068764A2 (en) | 2008-12-10 | 2010-06-17 | The General Hospital Corporation | Systems, apparatus and methods for extending imaging depth range of optical coherence tomography through optical sub-sampling |
| EP2382456A4 (en) * | 2009-01-26 | 2012-07-25 | Gen Hospital Corp | SYSTEM, METHOD AND COMPUTER MEDIUM FOR MICROSCOPY WITH A WIDE FIELD AND VERY HIGH RESOLUTION |
| EP2394336B1 (en) | 2009-02-04 | 2023-05-24 | The General Hospital Corporation | Apparatus and method for utilization of a high-speed optical wavelength tuning source |
| WO2010105197A2 (en) | 2009-03-12 | 2010-09-16 | The General Hospital Corporation | Non-contact optical system, computer-accessible medium and method for measuring at least one mechanical property of tissue using coherent speckle techniques(s) |
| US10492671B2 (en) | 2009-05-08 | 2019-12-03 | Novadaq Technologies ULC | Near infra red fluorescence imaging for visualization of blood vessels during endoscopic harvest |
| US9595028B2 (en) | 2009-06-08 | 2017-03-14 | Boku, Inc. | Systems and methods to add funds to an account via a mobile communication device |
| CN102469943A (zh) | 2009-07-14 | 2012-05-23 | 通用医疗公司 | 用于测量脉管内流动和压力的设备、系统和方法 |
| US20110071403A1 (en) * | 2009-09-21 | 2011-03-24 | Board Of Regents Of The University Of Texas System | Functional near-infrared fluorescence lymphatic mapping for diagnosing, accessing, monitoring and directing therapy of lymphatic disorders |
| WO2011044301A2 (en) * | 2009-10-06 | 2011-04-14 | The General Hospital Corporation | Apparatus and methods for imaging particular cells including eosinophils |
| US8518405B2 (en) | 2009-10-08 | 2013-08-27 | The University Of North Carolina At Charlotte | Tumor specific antibodies and uses therefor |
| EP2501288B1 (en) | 2009-11-19 | 2016-12-21 | Modulated Imaging Inc. | Method and apparatus for analysis of turbid media via single-element detection using structured illumination |
| WO2011072055A2 (en) * | 2009-12-08 | 2011-06-16 | The General Hospital Corporation | Methods and arrangements for analysis, diagnosis, and treatment monitoring of vocal folds by optical coherence tomography |
| LU91641B1 (en) * | 2010-01-21 | 2011-07-22 | Ct De Rech Public Gabriel Lippmann | Cancerous or pre-cancerous tissue visualization method and device |
| DK2542154T3 (da) * | 2010-03-05 | 2020-11-23 | Massachusetts Gen Hospital | Apparat til tilvejebringelse af elektromagnetisk stråling til en prøve |
| JP5566751B2 (ja) * | 2010-03-31 | 2014-08-06 | 富士フイルム株式会社 | 光断層情報生成装置、光強度分布算出方法および光強度分布算出プログラム |
| US9069130B2 (en) | 2010-05-03 | 2015-06-30 | The General Hospital Corporation | Apparatus, method and system for generating optical radiation from biological gain media |
| US8681247B1 (en) * | 2010-05-12 | 2014-03-25 | Li-Cor, Inc. | Field flattening correction method for fluorescence imaging system |
| US9557154B2 (en) | 2010-05-25 | 2017-01-31 | The General Hospital Corporation | Systems, devices, methods, apparatus and computer-accessible media for providing optical imaging of structures and compositions |
| WO2011150069A2 (en) | 2010-05-25 | 2011-12-01 | The General Hospital Corporation | Apparatus, systems, methods and computer-accessible medium for spectral analysis of optical coherence tomography images |
| JP6066901B2 (ja) | 2010-06-03 | 2017-01-25 | ザ ジェネラル ホスピタル コーポレイション | 1つまたは複数の管腔器官内または管腔器官にある構造を撮像するための装置およびデバイスのための方法 |
| GB201011913D0 (en) * | 2010-07-15 | 2010-09-01 | Lux Innovate Ltd | Detecting device |
| US9347894B2 (en) | 2010-09-01 | 2016-05-24 | Spectral Instruments Imaging, LLC | Methods and systems for producing visible light and x-ray image data |
| JP2013538350A (ja) | 2010-09-01 | 2013-10-10 | スペクトラル・インストゥルメンツ・イメージング・エルエルシー | 励起光源組立体 |
| CN101975769A (zh) * | 2010-09-17 | 2011-02-16 | 福建师范大学 | 一种基于不同波长光源激发的人体组织自体荧光检测系统 |
| JP5883018B2 (ja) | 2010-10-27 | 2016-03-09 | ザ ジェネラル ホスピタル コーポレイション | 少なくとも1つの血管内部の血圧を測定するための装置、システム、および方法 |
| US8721077B2 (en) | 2011-04-29 | 2014-05-13 | The General Hospital Corporation | Systems, methods and computer-readable medium for determining depth-resolved physical and/or optical properties of scattering media by analyzing measured data over a range of depths |
| JP2014523536A (ja) | 2011-07-19 | 2014-09-11 | ザ ジェネラル ホスピタル コーポレイション | 光コヒーレンストモグラフィーにおいて偏波モード分散補償を提供するためのシステム、方法、装置およびコンピュータアクセス可能な媒体 |
| EP3835718B1 (en) | 2011-08-25 | 2023-07-26 | The General Hospital Corporation | Apparatus for providing micro-optical coherence tomography inside a respiratory system |
| EP2769491A4 (en) | 2011-10-18 | 2015-07-22 | Gen Hospital Corp | DEVICE AND METHOD FOR PRODUCING AND / OR PROVIDING RECIRCULATING OPTICAL DELAY (DE) |
| JP5970785B2 (ja) * | 2011-11-16 | 2016-08-17 | ソニー株式会社 | 生体計測装置、生体計測方法、プログラムおよび記録媒体 |
| EP2833776A4 (en) | 2012-03-30 | 2015-12-09 | Gen Hospital Corp | PICTURE SYSTEM, PROCESS AND DISTAL CONNECTION TO MULTIDIRECTIONAL VISION DOSCOPY |
| JP2015517387A (ja) | 2012-05-21 | 2015-06-22 | ザ ジェネラル ホスピタル コーポレイション | カプセル顕微鏡検査のための装置、デバイスおよび方法 |
| US10278585B2 (en) | 2012-06-21 | 2019-05-07 | Novadaq Technologies ULC | Quantification and analysis of angiography and perfusion |
| US9415550B2 (en) | 2012-08-22 | 2016-08-16 | The General Hospital Corporation | System, method, and computer-accessible medium for fabrication miniature endoscope using soft lithography |
| CN105190308B (zh) | 2012-11-07 | 2021-05-28 | 调节成像公司 | 用于测量混浊样本的设备和方法 |
| WO2014120791A1 (en) | 2013-01-29 | 2014-08-07 | The General Hospital Corporation | Apparatus, systems and methods for providing information regarding the aortic valve |
| US11179028B2 (en) | 2013-02-01 | 2021-11-23 | The General Hospital Corporation | Objective lens arrangement for confocal endomicroscopy |
| EP2967491B1 (en) | 2013-03-15 | 2022-05-11 | The General Hospital Corporation | A transesophageal endoscopic system for determining a mixed venous oxygen saturation of a pulmonary artery |
| DE102013008003B4 (de) | 2013-05-08 | 2015-03-19 | Freshdetect Gmbh | Messgerät zum Messen eines Oberflächenbelags auf einem Messobjekt, insbesondere auf einem Lebensmittel, und dessen Verwendung |
| WO2014186353A1 (en) | 2013-05-13 | 2014-11-20 | The General Hospital Corporation | Detecting self-interefering fluorescence phase and amplitude |
| EP3021734B1 (en) | 2013-07-19 | 2020-04-08 | The General Hospital Corporation | Imaging apparatus which utilizes multidirectional field of view endoscopy |
| EP3021735A4 (en) | 2013-07-19 | 2017-04-19 | The General Hospital Corporation | Determining eye motion by imaging retina. with feedback |
| WO2015013651A2 (en) | 2013-07-26 | 2015-01-29 | The General Hospital Corporation | System, apparatus and method utilizing optical dispersion for fourier-domain optical coherence tomography |
| US11096584B2 (en) * | 2013-11-14 | 2021-08-24 | The George Washington University | Systems and methods for determining lesion depth using fluorescence imaging |
| US9733460B2 (en) | 2014-01-08 | 2017-08-15 | The General Hospital Corporation | Method and apparatus for microscopic imaging |
| WO2015116986A2 (en) | 2014-01-31 | 2015-08-06 | The General Hospital Corporation | System and method for facilitating manual and/or automatic volumetric imaging with real-time tension or force feedback using a tethered imaging device |
| US10228556B2 (en) | 2014-04-04 | 2019-03-12 | The General Hospital Corporation | Apparatus and method for controlling propagation and/or transmission of electromagnetic radiation in flexible waveguide(s) |
| AU2015292498B2 (en) | 2014-07-23 | 2020-11-05 | Ohio State Innovation Foundation | Methods and compositions related to antibody fragments that bind to tumor-associated glycoprotein 72 (TAG-72) |
| EP3957232B1 (en) | 2014-07-24 | 2025-12-31 | University Health Network | DATA COLLECTION AND ANALYSIS FOR DIAGNOSTIC PURPOSES |
| US10912462B2 (en) | 2014-07-25 | 2021-02-09 | The General Hospital Corporation | Apparatus, devices and methods for in vivo imaging and diagnosis |
| AU2015327665B2 (en) | 2014-09-29 | 2018-09-27 | Stryker European Operations Limited | Imaging a target fluorophore in a biological material in the presence of autofluorescence |
| US10631746B2 (en) | 2014-10-09 | 2020-04-28 | Novadaq Technologies ULC | Quantification of absolute blood flow in tissue using fluorescence-mediated photoplethysmography |
| WO2016073476A1 (en) * | 2014-11-03 | 2016-05-12 | The George Washington University | Systems and methods for lesion assessment |
| US9626754B2 (en) * | 2015-05-28 | 2017-04-18 | Jabil Circuit, Inc. | System, apparatus and method for dispensed adhesive material inspection |
| US10084365B1 (en) | 2016-02-04 | 2018-09-25 | Harivallabh Pandya | Electromagnetic machinery systems, device, assemblies, methods, processes, uses, and apparatus operable as a motor or generator with one or more stator coils, at least one permanent magnet rotor, and associated circuitry |
| US11140305B2 (en) | 2017-02-10 | 2021-10-05 | Stryker European Operations Limited | Open-field handheld fluorescence imaging systems and methods |
| US10378006B2 (en) | 2017-04-19 | 2019-08-13 | The Florida International University Board Of Trustees | Near-infrared ray exposure system for biological studies |
| WO2019109091A1 (en) * | 2017-12-03 | 2019-06-06 | Munro Design & Technologies, Llc | Digital image processing systems for three-dimensional imaging systems with image intensifiers and methods thereof |
| CN112449683B (zh) * | 2018-04-26 | 2024-07-23 | 达特默斯大学托管会 | 用于确定表面下荧光物体的深度和浓度的装置和方法 |
| DE102018126183B4 (de) * | 2018-10-22 | 2020-08-06 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren zur Bestimmung der Konzentration eines fluoreszierenden und/oder fluoreszenzmarkierten Analyten und Kalibrierverfahren zur Vorbereitung dieser Bestimmung |
| JP7240995B2 (ja) * | 2019-09-17 | 2023-03-16 | 株式会社アドバンテスト | ファントムおよび蛍光検出装置 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4541438A (en) * | 1983-06-02 | 1985-09-17 | The Johns Hopkins University | Localization of cancerous tissue by monitoring infrared fluorescence emitted by intravenously injected porphyrin tumor-specific markers excited by long wavelength light |
| US5353799A (en) * | 1991-01-22 | 1994-10-11 | Non Invasive Technology, Inc. | Examination of subjects using photon migration with high directionality techniques |
| US5022757A (en) * | 1989-01-23 | 1991-06-11 | Modell Mark D | Heterodyne system and method for sensing a target substance |
| JP2525894B2 (ja) * | 1989-04-07 | 1996-08-21 | 浜松ホトニクス株式会社 | 半導体試料の螢光特性検査装置 |
| US5421337A (en) * | 1989-04-14 | 1995-06-06 | Massachusetts Institute Of Technology | Spectral diagnosis of diseased tissue |
| US5070455A (en) * | 1989-11-22 | 1991-12-03 | Singer Imaging, Inc. | Imaging system and method using scattered and diffused radiation |
| US5142372A (en) * | 1990-03-08 | 1992-08-25 | Alfano Robert R | Three-dimensional optical imaging of semi-transparent and opaque objects using ultrashort light pulses, a streak camera and a coherent fiber bundle |
| US5213105A (en) * | 1990-12-04 | 1993-05-25 | Research Corporation Technologies, Inc. | Frequency domain optical imaging using diffusion of intensity modulated radiation |
| CA2042075C (en) * | 1991-05-08 | 2001-01-23 | Branko Palcic | Endoscopic imaging system |
| US5413098A (en) * | 1991-12-24 | 1995-05-09 | Sextant Medical Corporation | Path constrained spectrophotometer and method for determination of spatial distribution of light or other radiation scattering and absorbing substances in a radiation scattering medium |
| JP3107914B2 (ja) * | 1992-07-20 | 2000-11-13 | 浜松ホトニクス株式会社 | 散乱吸収体内部の吸収情報計測装置及び方法 |
| US5452723A (en) * | 1992-07-24 | 1995-09-26 | Massachusetts Institute Of Technology | Calibrated spectrographic imaging |
| US5421339A (en) * | 1993-05-12 | 1995-06-06 | Board Of Regents, The University Of Texas System | Diagnosis of dysplasia using laser induced fluoroescence |
| US5340991A (en) * | 1993-05-21 | 1994-08-23 | The Board Of Regents Of The University Of Oklahoma | Fluorokinetic analysis of diffusion from a vessel |
| CA2175348A1 (en) * | 1993-10-29 | 1995-05-04 | Arjun G. Yodh | Object imaging using diffuse light |
| US5590660A (en) * | 1994-03-28 | 1997-01-07 | Xillix Technologies Corp. | Apparatus and method for imaging diseased tissue using integrated autofluorescence |
| US5579773A (en) * | 1994-09-30 | 1996-12-03 | Martin Marietta Energy Systems, Inc. | Laser-induced differential normalized fluorescence method for cancer diagnosis |
| US5647368A (en) * | 1996-02-28 | 1997-07-15 | Xillix Technologies Corp. | Imaging system for detecting diseased tissue using native fluorsecence in the gastrointestinal and respiratory tract |
-
1996
- 1996-08-23 CA CA002230228A patent/CA2230228C/en not_active Expired - Lifetime
- 1996-08-23 CN CN96197632A patent/CN1200174A/zh active Pending
- 1996-08-23 JP JP51047197A patent/JP3819032B2/ja not_active Expired - Lifetime
- 1996-08-23 EP EP96929029A patent/EP0846262A4/en not_active Withdrawn
- 1996-08-23 AU AU11307/97A patent/AU1130797A/en not_active Abandoned
- 1996-08-23 WO PCT/US1996/013658 patent/WO1997008538A1/en not_active Ceased
- 1996-08-23 US US08/702,060 patent/US5865754A/en not_active Expired - Lifetime
- 1996-08-23 MX MX9801351A patent/MX9801351A/es not_active IP Right Cessation
-
1998
- 1998-02-23 NO NO980750A patent/NO980750L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO980750L (no) | 1998-04-23 |
| WO1997008538A1 (en) | 1997-03-06 |
| US5865754A (en) | 1999-02-02 |
| CN1200174A (zh) | 1998-11-25 |
| NO980750D0 (no) | 1998-02-23 |
| MX9801351A (es) | 1998-07-31 |
| CA2230228A1 (en) | 1997-03-06 |
| AU1130797A (en) | 1997-03-19 |
| CA2230228C (en) | 2006-11-14 |
| JP2000500228A (ja) | 2000-01-11 |
| EP0846262A4 (en) | 1999-11-03 |
| EP0846262A1 (en) | 1998-06-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP3819032B2 (ja) | 組織およびその他のランダム媒体における蛍光寿命に基づく撮像および分光分析 | |
| US7328059B2 (en) | Imaging of light scattering tissues with fluorescent contrast agents | |
| Godavarty et al. | Three‐dimensional fluorescence lifetime tomography | |
| US7890157B2 (en) | Method for fluorescence lifetime imaging microscopy and spectroscopy | |
| JP4271040B2 (ja) | 実時間の光学的トモグラフィーの正規化された差方法の変更 | |
| Godavarty et al. | Fluorescence-enhanced optical imaging in large tissue volumes using a gain-modulated ICCD camera | |
| US7403812B2 (en) | Method and apparatus for determining target depth, brightness and size within a body region | |
| JP3958798B2 (ja) | 蛍光造影剤を用いた光散乱組織の撮像 | |
| US8263947B2 (en) | Method and device for localising fluorophores or absorbers in a surrounding medium | |
| US8847175B2 (en) | Method for locating an optical marker in a diffusing medium | |
| US8886284B2 (en) | Devices and methods for combined optical and magnetic resonance imaging | |
| US20090216457A1 (en) | Method for improving fluorescence image contrast | |
| Godavarty et al. | Fluorescence‐enhanced optical imaging of large phantoms using single and simultaneous dual point illumination geometries | |
| JP2009515583A (ja) | 光学蛍光断層撮影のための吸収及び散乱マップ再構成 | |
| JP4567318B2 (ja) | 生体組織部分内の領域の位置測定方法および装置 | |
| Paithankar et al. | Fluorescence lifetime imaging with frequency-domain photon migration measurement | |
| No et al. | 3D Image Reconstruction System for Cancerous Tumors Analysis Based on Diffuse Optical Tomography with Blender | |
| Darne et al. | Radiofrequency circuit design and performance evaluation for small animal frequency-domain NIR fluorescence optical tomography | |
| Chang et al. | Dependence of image quality on image operator and noise for optical diffusion tomography | |
| Ramírez-Salinas et al. | 3D Image Reconstruction System for Cancerous Tumors Analysis Based on Diffuse Optical Tomography with Blender | |
| Riley et al. | Time-resolved lifetime fluorescence imaging–an inverse model based on analytical solutions | |
| Freiberger et al. | 3D Optical Imaging of Fluorescent Agents in Biological Tissues | |
| Kuwana et al. | Eva M. Sevick-Muraca |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20050412 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20050711 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20050822 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20051012 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20051206 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20060306 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20060516 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20060614 |
|
| R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20100623 Year of fee payment: 4 |