JP3819032B2 - 組織およびその他のランダム媒体における蛍光寿命に基づく撮像および分光分析 - Google Patents
組織およびその他のランダム媒体における蛍光寿命に基づく撮像および分光分析 Download PDFInfo
- Publication number
- JP3819032B2 JP3819032B2 JP51047197A JP51047197A JP3819032B2 JP 3819032 B2 JP3819032 B2 JP 3819032B2 JP 51047197 A JP51047197 A JP 51047197A JP 51047197 A JP51047197 A JP 51047197A JP 3819032 B2 JP3819032 B2 JP 3819032B2
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- Prior art keywords
- fluorescence
- tissue
- light
- emission
- excitation
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- Expired - Lifetime
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
- G01J3/4406—Fluorescence spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/4795—Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Spectroscopy & Molecular Physics (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Optics & Photonics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US274695P | 1995-08-24 | 1995-08-24 | |
| US60/002,746 | 1995-08-24 | ||
| PCT/US1996/013658 WO1997008538A1 (en) | 1995-08-24 | 1996-08-23 | Fluorescence lifetime-based imaging and spectroscopy in tissues and other random media |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2000500228A JP2000500228A (ja) | 2000-01-11 |
| JP2000500228A5 JP2000500228A5 (enExample) | 2004-09-09 |
| JP3819032B2 true JP3819032B2 (ja) | 2006-09-06 |
Family
ID=21702295
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51047197A Expired - Lifetime JP3819032B2 (ja) | 1995-08-24 | 1996-08-23 | 組織およびその他のランダム媒体における蛍光寿命に基づく撮像および分光分析 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5865754A (enExample) |
| EP (1) | EP0846262A4 (enExample) |
| JP (1) | JP3819032B2 (enExample) |
| CN (1) | CN1200174A (enExample) |
| AU (1) | AU1130797A (enExample) |
| CA (1) | CA2230228C (enExample) |
| MX (1) | MX9801351A (enExample) |
| NO (1) | NO980750L (enExample) |
| WO (1) | WO1997008538A1 (enExample) |
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| JP7240995B2 (ja) * | 2019-09-17 | 2023-03-16 | 株式会社アドバンテスト | ファントムおよび蛍光検出装置 |
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|---|---|---|---|---|
| US4541438A (en) * | 1983-06-02 | 1985-09-17 | The Johns Hopkins University | Localization of cancerous tissue by monitoring infrared fluorescence emitted by intravenously injected porphyrin tumor-specific markers excited by long wavelength light |
| US5353799A (en) * | 1991-01-22 | 1994-10-11 | Non Invasive Technology, Inc. | Examination of subjects using photon migration with high directionality techniques |
| US5022757A (en) * | 1989-01-23 | 1991-06-11 | Modell Mark D | Heterodyne system and method for sensing a target substance |
| JP2525894B2 (ja) * | 1989-04-07 | 1996-08-21 | 浜松ホトニクス株式会社 | 半導体試料の螢光特性検査装置 |
| US5421337A (en) * | 1989-04-14 | 1995-06-06 | Massachusetts Institute Of Technology | Spectral diagnosis of diseased tissue |
| US5070455A (en) * | 1989-11-22 | 1991-12-03 | Singer Imaging, Inc. | Imaging system and method using scattered and diffused radiation |
| US5142372A (en) * | 1990-03-08 | 1992-08-25 | Alfano Robert R | Three-dimensional optical imaging of semi-transparent and opaque objects using ultrashort light pulses, a streak camera and a coherent fiber bundle |
| US5213105A (en) * | 1990-12-04 | 1993-05-25 | Research Corporation Technologies, Inc. | Frequency domain optical imaging using diffusion of intensity modulated radiation |
| CA2042075C (en) * | 1991-05-08 | 2001-01-23 | Branko Palcic | Endoscopic imaging system |
| US5413098A (en) * | 1991-12-24 | 1995-05-09 | Sextant Medical Corporation | Path constrained spectrophotometer and method for determination of spatial distribution of light or other radiation scattering and absorbing substances in a radiation scattering medium |
| JP3107914B2 (ja) * | 1992-07-20 | 2000-11-13 | 浜松ホトニクス株式会社 | 散乱吸収体内部の吸収情報計測装置及び方法 |
| US5452723A (en) * | 1992-07-24 | 1995-09-26 | Massachusetts Institute Of Technology | Calibrated spectrographic imaging |
| US5421339A (en) * | 1993-05-12 | 1995-06-06 | Board Of Regents, The University Of Texas System | Diagnosis of dysplasia using laser induced fluoroescence |
| US5340991A (en) * | 1993-05-21 | 1994-08-23 | The Board Of Regents Of The University Of Oklahoma | Fluorokinetic analysis of diffusion from a vessel |
| JPH09504964A (ja) * | 1993-10-29 | 1997-05-20 | ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルベニア | 拡散光を用いた対象物撮像 |
| US5590660A (en) * | 1994-03-28 | 1997-01-07 | Xillix Technologies Corp. | Apparatus and method for imaging diseased tissue using integrated autofluorescence |
| US5579773A (en) * | 1994-09-30 | 1996-12-03 | Martin Marietta Energy Systems, Inc. | Laser-induced differential normalized fluorescence method for cancer diagnosis |
| US5647368A (en) * | 1996-02-28 | 1997-07-15 | Xillix Technologies Corp. | Imaging system for detecting diseased tissue using native fluorsecence in the gastrointestinal and respiratory tract |
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1996
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- 1996-08-23 EP EP96929029A patent/EP0846262A4/en not_active Withdrawn
- 1996-08-23 MX MX9801351A patent/MX9801351A/es not_active IP Right Cessation
- 1996-08-23 US US08/702,060 patent/US5865754A/en not_active Expired - Lifetime
- 1996-08-23 CN CN96197632A patent/CN1200174A/zh active Pending
- 1996-08-23 CA CA002230228A patent/CA2230228C/en not_active Expired - Lifetime
- 1996-08-23 WO PCT/US1996/013658 patent/WO1997008538A1/en not_active Ceased
- 1996-08-23 JP JP51047197A patent/JP3819032B2/ja not_active Expired - Lifetime
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1998
- 1998-02-23 NO NO980750A patent/NO980750L/no not_active Application Discontinuation
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| NO980750L (no) | 1998-04-23 |
| NO980750D0 (no) | 1998-02-23 |
| CN1200174A (zh) | 1998-11-25 |
| WO1997008538A1 (en) | 1997-03-06 |
| JP2000500228A (ja) | 2000-01-11 |
| US5865754A (en) | 1999-02-02 |
| MX9801351A (es) | 1998-07-31 |
| CA2230228C (en) | 2006-11-14 |
| CA2230228A1 (en) | 1997-03-06 |
| AU1130797A (en) | 1997-03-19 |
| EP0846262A4 (en) | 1999-11-03 |
| EP0846262A1 (en) | 1998-06-10 |
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