JP3786945B2 - 治療薬剤 - Google Patents

治療薬剤 Download PDF

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Publication number
JP3786945B2
JP3786945B2 JP2004561668A JP2004561668A JP3786945B2 JP 3786945 B2 JP3786945 B2 JP 3786945B2 JP 2004561668 A JP2004561668 A JP 2004561668A JP 2004561668 A JP2004561668 A JP 2004561668A JP 3786945 B2 JP3786945 B2 JP 3786945B2
Authority
JP
Japan
Prior art keywords
phenyl
benzyl
pharmaceutically acceptable
compounds
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2004561668A
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English (en)
Japanese (ja)
Other versions
JP2006511572A (ja
Inventor
リンドステット・アルスターマーク，エヴァ−ロッテ
オルソン，アンナ・クリスティーナ
リー，ランナ
オーレル，カール−ヨハン
ミニディス，アンナ
ヨウセフィ−サラクデ，エスマイル
ダールストロム，ミカエル・ウルフ・ヨハン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of JP2006511572A publication Critical patent/JP2006511572A/ja
Application granted granted Critical
Publication of JP3786945B2 publication Critical patent/JP3786945B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
    • C07C235/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2004561668A 2002-12-21 2003-12-19 治療薬剤 Expired - Fee Related JP3786945B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0229931.1A GB0229931D0 (en) 2002-12-21 2002-12-21 Therapeutic agents
GB0229931.1 2002-12-21
PCT/GB2003/005602 WO2004056748A1 (en) 2002-12-21 2003-12-19 Therapeutic agents

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2005253346A Division JP2006045240A (ja) 2002-12-21 2005-09-01 治療薬剤

Publications (2)

Publication Number Publication Date
JP2006511572A JP2006511572A (ja) 2006-04-06
JP3786945B2 true JP3786945B2 (ja) 2006-06-21

Family

ID=9950253

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2004561668A Expired - Fee Related JP3786945B2 (ja) 2002-12-21 2003-12-19 治療薬剤
JP2005253346A Pending JP2006045240A (ja) 2002-12-21 2005-09-01 治療薬剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2005253346A Pending JP2006045240A (ja) 2002-12-21 2005-09-01 治療薬剤

Country Status (21)

Country Link
US (1) US7462644B2 (enExample)
EP (1) EP1572626A1 (enExample)
JP (2) JP3786945B2 (enExample)
KR (1) KR20050089065A (enExample)
CN (1) CN1308291C (enExample)
AR (1) AR042632A1 (enExample)
AU (1) AU2003290309B2 (enExample)
BR (1) BR0317458A (enExample)
CA (1) CA2508851A1 (enExample)
CL (1) CL2003002683A1 (enExample)
CO (1) CO5580820A2 (enExample)
GB (1) GB0229931D0 (enExample)
IS (1) IS7946A (enExample)
MX (1) MXPA05006812A (enExample)
NO (1) NO20052914L (enExample)
PL (1) PL377144A1 (enExample)
RU (1) RU2005117792A (enExample)
TW (1) TW200508180A (enExample)
UA (1) UA80729C2 (enExample)
WO (1) WO2004056748A1 (enExample)
ZA (1) ZA200504730B (enExample)

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Also Published As

Publication number Publication date
JP2006045240A (ja) 2006-02-16
GB0229931D0 (en) 2003-01-29
RU2005117792A (ru) 2006-01-27
PL377144A1 (pl) 2006-01-23
MXPA05006812A (es) 2005-09-08
AR042632A1 (es) 2005-06-29
CN1753862A (zh) 2006-03-29
UA80729C2 (en) 2007-10-25
AU2003290309B2 (en) 2007-01-18
KR20050089065A (ko) 2005-09-07
IS7946A (is) 2005-07-19
WO2004056748A1 (en) 2004-07-08
TW200508180A (en) 2005-03-01
CL2003002683A1 (es) 2005-04-08
AU2003290309A1 (en) 2004-07-14
CN1308291C (zh) 2007-04-04
JP2006511572A (ja) 2006-04-06
NO20052914D0 (no) 2005-06-15
BR0317458A (pt) 2005-11-16
CO5580820A2 (es) 2005-11-30
NO20052914L (no) 2005-07-19
US7462644B2 (en) 2008-12-09
US20050131068A1 (en) 2005-06-16
EP1572626A1 (en) 2005-09-14
CA2508851A1 (en) 2004-07-08
ZA200504730B (en) 2006-09-27

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