TW200508180A - Therapeutic agents - Google Patents

Therapeutic agents

Info

Publication number
TW200508180A
TW200508180A TW092134839A TW92134839A TW200508180A TW 200508180 A TW200508180 A TW 200508180A TW 092134839 A TW092134839 A TW 092134839A TW 92134839 A TW92134839 A TW 92134839A TW 200508180 A TW200508180 A TW 200508180A
Authority
TW
Taiwan
Prior art keywords
therapeutic agents
dyslipidemias
trifluoromethoxy
enantiomer
prodrugs
Prior art date
Application number
TW092134839A
Other languages
English (en)
Chinese (zh)
Inventor
Lindstedt Eva Lotte Alstermark
Lanna Li
Christina Anna Olsson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of TW200508180A publication Critical patent/TW200508180A/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
    • C07C235/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW092134839A 2002-12-21 2003-12-10 Therapeutic agents TW200508180A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0229931.1A GB0229931D0 (en) 2002-12-21 2002-12-21 Therapeutic agents

Publications (1)

Publication Number Publication Date
TW200508180A true TW200508180A (en) 2005-03-01

Family

ID=9950253

Family Applications (1)

Application Number Title Priority Date Filing Date
TW092134839A TW200508180A (en) 2002-12-21 2003-12-10 Therapeutic agents

Country Status (21)

Country Link
US (1) US7462644B2 (enExample)
EP (1) EP1572626A1 (enExample)
JP (2) JP3786945B2 (enExample)
KR (1) KR20050089065A (enExample)
CN (1) CN1308291C (enExample)
AR (1) AR042632A1 (enExample)
AU (1) AU2003290309B2 (enExample)
BR (1) BR0317458A (enExample)
CA (1) CA2508851A1 (enExample)
CL (1) CL2003002683A1 (enExample)
CO (1) CO5580820A2 (enExample)
GB (1) GB0229931D0 (enExample)
IS (1) IS7946A (enExample)
MX (1) MXPA05006812A (enExample)
NO (1) NO20052914L (enExample)
PL (1) PL377144A1 (enExample)
RU (1) RU2005117792A (enExample)
TW (1) TW200508180A (enExample)
UA (1) UA80729C2 (enExample)
WO (1) WO2004056748A1 (enExample)
ZA (1) ZA200504730B (enExample)

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Also Published As

Publication number Publication date
JP2006511572A (ja) 2006-04-06
RU2005117792A (ru) 2006-01-27
AU2003290309B2 (en) 2007-01-18
CL2003002683A1 (es) 2005-04-08
MXPA05006812A (es) 2005-09-08
AR042632A1 (es) 2005-06-29
AU2003290309A1 (en) 2004-07-14
JP2006045240A (ja) 2006-02-16
IS7946A (is) 2005-07-19
US7462644B2 (en) 2008-12-09
NO20052914L (no) 2005-07-19
US20050131068A1 (en) 2005-06-16
EP1572626A1 (en) 2005-09-14
CN1308291C (zh) 2007-04-04
ZA200504730B (en) 2006-09-27
CA2508851A1 (en) 2004-07-08
UA80729C2 (en) 2007-10-25
JP3786945B2 (ja) 2006-06-21
PL377144A1 (pl) 2006-01-23
KR20050089065A (ko) 2005-09-07
GB0229931D0 (en) 2003-01-29
CN1753862A (zh) 2006-03-29
WO2004056748A1 (en) 2004-07-08
NO20052914D0 (no) 2005-06-15
CO5580820A2 (es) 2005-11-30
BR0317458A (pt) 2005-11-16

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