JP3162232B2 - 二環式芳香族スルホン酸、塩化スルホニルおよびスルホンアミドの合成 - Google Patents

二環式芳香族スルホン酸、塩化スルホニルおよびスルホンアミドの合成

Info

Publication number
JP3162232B2
JP3162232B2 JP20152593A JP20152593A JP3162232B2 JP 3162232 B2 JP3162232 B2 JP 3162232B2 JP 20152593 A JP20152593 A JP 20152593A JP 20152593 A JP20152593 A JP 20152593A JP 3162232 B2 JP3162232 B2 JP 3162232B2
Authority
JP
Japan
Prior art keywords
sulfonamide
bicyclic aromatic
temperature
reaction
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP20152593A
Other languages
English (en)
Japanese (ja)
Other versions
JPH06199825A (ja
Inventor
エディ・ビ−ピン・タオ
ウイリアム・デイビッド・ミラー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of JPH06199825A publication Critical patent/JPH06199825A/ja
Application granted granted Critical
Publication of JP3162232B2 publication Critical patent/JP3162232B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Furan Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP20152593A 1992-08-19 1993-08-13 二環式芳香族スルホン酸、塩化スルホニルおよびスルホンアミドの合成 Expired - Fee Related JP3162232B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US932404 1992-08-19
US07/932,404 US5387681A (en) 1992-08-19 1992-08-19 Synthesis of bicyclic aromatic sulfonic acids sulfonyl chlorides and sulfonamides

Publications (2)

Publication Number Publication Date
JPH06199825A JPH06199825A (ja) 1994-07-19
JP3162232B2 true JP3162232B2 (ja) 2001-04-25

Family

ID=25462254

Family Applications (1)

Application Number Title Priority Date Filing Date
JP20152593A Expired - Fee Related JP3162232B2 (ja) 1992-08-19 1993-08-13 二環式芳香族スルホン酸、塩化スルホニルおよびスルホンアミドの合成

Country Status (15)

Country Link
US (1) US5387681A (https=)
EP (1) EP0583960B1 (https=)
JP (1) JP3162232B2 (https=)
KR (1) KR100261824B1 (https=)
AT (1) ATE153333T1 (https=)
BR (1) BR9303223A (https=)
CA (1) CA2103930A1 (https=)
DE (1) DE69310836T2 (https=)
DK (1) DK0583960T3 (https=)
ES (1) ES2103434T3 (https=)
GR (1) GR3024121T3 (https=)
HU (1) HU219235B (https=)
IL (3) IL119480A (https=)
MX (1) MX9304960A (https=)
TW (1) TW232688B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6140505A (en) * 1995-03-10 2000-10-31 G. D. Searle & Co. Synthesis of benzo fused heterocyclic sulfonyl chlorides
EP0929540A4 (en) * 1996-10-04 2001-12-12 Lilly Co Eli ANTI-TUMOR COMPOSITIONS AND THERAPEUTIC METHODS
US8829198B2 (en) * 2007-10-31 2014-09-09 Proteotech Inc Compounds, compositions and methods for the treatment of beta-amyloid diseases and synucleinopathies
US8916598B2 (en) 2003-05-30 2014-12-23 Proteotech Inc Compounds, compositions, and methods for the treatment of β-amyloid diseases and synucleinopathies
US20100331380A1 (en) * 2009-06-29 2010-12-30 Esposito Luke A Compounds, Compositions, and Methods for the Treatment of Beta-Amyloid Diseases and Synucleinopathies
JP4596165B2 (ja) * 2003-06-25 2010-12-08 日産化学工業株式会社 １，４−ベンゾジオキサンスルホン酸化合物及び電子受容性物質としての利用
US7378441B2 (en) 2004-05-07 2008-05-27 Sequoia Pharmaceuticals, Inc. Resistance-repellent retroviral protease inhibitors
EP2231596A4 (en) 2007-12-14 2012-06-06 Univ Georgetown INHIBITORS OF HISTONATE ACETYLASE
WO2009111611A2 (en) * 2008-03-05 2009-09-11 Proteotech Inc. Compounds, compositions and methods for the treatment of islet amyloid polypeptide (iapp) accumulation in diabetes

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH368076A (fr) * 1961-02-24 1963-03-15 Mefina Sa Fusée pour projectile
DE3419795A1 (de) * 1984-05-26 1985-11-28 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von acyloxybenzolsulfonsaeuren und ihrer alkali- und erdalkalisalze
US4845128A (en) * 1984-06-27 1989-07-04 Eli Lilly And Company N([(4-trifluoromethylphenyl)amino]carbonyl)benzene sulfonamides
JPS6163671A (ja) * 1984-09-05 1986-04-01 Shionogi & Co Ltd ２，３−ジヒドロベンゾフラン−５−スルホンアミド誘導体および降圧利尿剤
US4560771A (en) * 1984-10-01 1985-12-24 Ciba Geigy Corporation Process for the preparation of 1,2-benzoxathiines
IL83215A (en) * 1986-07-23 1991-12-15 Lilly Co Eli Synthesis of bicyclic heteroaromatic sulfonyl chlorides
JPH01100164A (ja) * 1987-10-12 1989-04-18 Shionogi & Co Ltd スルファモイル−２−ベンゾフランカルボン酸誘導体
NZ238911A (en) * 1990-07-17 1993-10-26 Lilly Co Eli Furyl, pyrrolyl and thienyl sulphonyl urea derivatives, pharmaceutical compositions and intermediates therefor
JP5015452B2 (ja) * 2005-12-27 2012-08-29 京セラ株式会社 セルスタック装置及び燃料電池
JP6213894B2 (ja) * 2012-09-25 2017-10-18 Toto株式会社 固体酸化物型燃料電池装置
JP2014143162A (ja) * 2012-12-26 2014-08-07 Kyocera Corp セルスタック装置および燃料電池装置

Also Published As

Publication number Publication date
IL106669A (en) 1999-12-31
EP0583960A2 (en) 1994-02-23
GR3024121T3 (en) 1997-10-31
BR9303223A (pt) 1994-03-01
KR940003948A (ko) 1994-03-14
JPH06199825A (ja) 1994-07-19
EP0583960A3 (en) 1994-06-15
EP0583960B1 (en) 1997-05-21
DK0583960T3 (da) 1997-08-25
DE69310836T2 (de) 1997-10-09
DE69310836D1 (de) 1997-06-26
KR100261824B1 (ko) 2000-07-15
HUT64953A (en) 1994-03-28
ES2103434T3 (es) 1997-09-16
IL119480A (en) 1999-12-22
HU9302363D0 (en) 1993-10-28
IL106669A0 (en) 1993-12-08
CA2103930A1 (en) 1994-02-20
MX9304960A (es) 1994-05-31
US5387681A (en) 1995-02-07
HU219235B (en) 2001-03-28
IL119480A0 (en) 1997-01-10
TW232688B (https=) 1994-10-21
ATE153333T1 (de) 1997-06-15

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Effective date: 20010130

LAPS Cancellation because of no payment of annual fees