JP2809509B2 - 三環式化合物の製造方法 - Google Patents

三環式化合物の製造方法

Info

Publication number
JP2809509B2
JP2809509B2 JP6516654A JP51665494A JP2809509B2 JP 2809509 B2 JP2809509 B2 JP 2809509B2 JP 6516654 A JP6516654 A JP 6516654A JP 51665494 A JP51665494 A JP 51665494A JP 2809509 B2 JP2809509 B2 JP 2809509B2
Authority
JP
Japan
Prior art keywords
formula
compound
amino
following formula
alkali metal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP6516654A
Other languages
English (en)
Japanese (ja)
Other versions
JPH08502756A (ja
Inventor
カルプフ，エム
トラサルディ，アール
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of JPH08502756A publication Critical patent/JPH08502756A/ja
Application granted granted Critical
Publication of JP2809509B2 publication Critical patent/JP2809509B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/26—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C243/28—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of a saturated carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP6516654A 1993-01-23 1994-01-19 三環式化合物の製造方法 Expired - Lifetime JP2809509B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93101031 1993-01-23
EP93101031.8 1993-01-23

Publications (2)

Publication Number Publication Date
JPH08502756A JPH08502756A (ja) 1996-03-26
JP2809509B2 true JP2809509B2 (ja) 1998-10-08

Family

ID=8212553

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6516654A Expired - Lifetime JP2809509B2 (ja) 1993-01-23 1994-01-19 三環式化合物の製造方法

Country Status (16)

Country Link
US (1) US5892040A (enExample)
EP (1) EP0680482B1 (enExample)
JP (1) JP2809509B2 (enExample)
KR (1) KR100256461B1 (enExample)
CN (1) CN1053907C (enExample)
AT (1) ATE151075T1 (enExample)
AU (1) AU688301B2 (enExample)
CA (1) CA2153984C (enExample)
DE (1) DE69402412T2 (enExample)
DK (1) DK0680482T3 (enExample)
ES (1) ES2100695T3 (enExample)
GR (1) GR3023195T3 (enExample)
NZ (1) NZ261106A (enExample)
TW (1) TW266208B (enExample)
WO (1) WO1994017074A1 (enExample)
ZA (1) ZA94433B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4329600A1 (de) * 1993-09-02 1995-03-09 Bayer Ag Pyrido [1,2,3-d,e] [1,3,4] benzoxadiazinderivate
CN101020647B (zh) * 2007-02-14 2011-03-30 杭州师范学院 一种β-环丙胺基丙烯酸(酯)的合成方法
EP2332916A3 (en) * 2009-11-19 2011-08-03 Krka Tovarna Zdravil, D.D., Novo Mesto A process for a preparation of marbofloxacin and intermediate thereof
CN102060860B (zh) * 2011-01-07 2013-04-10 宁波美诺华药业股份有限公司 一种马波沙星的制备方法
CN102617595A (zh) * 2012-03-23 2012-08-01 江西华士药业有限公司 氟喹诺酮类抗菌药马波沙星的制备方法
CN107383058B (zh) * 2017-08-28 2019-07-26 海门慧聚药业有限公司 马波沙星的制备
CN107522718B (zh) * 2017-09-14 2019-11-08 浙江国邦药业有限公司 一种马波沙星的合成方法
CN114249749B (zh) * 2022-01-08 2024-03-22 天象生物药业邢台有限责任公司 一种马波沙星甲酸盐的转化方法
CN116987096B (zh) * 2023-08-06 2025-07-01 石家庄学院 一种马波沙星的制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60204476A (ja) * 1984-03-29 1985-10-16 株式会社東芝 電子部品の包装容器および包装方法
WO1992015584A1 (en) 1991-02-28 1992-09-17 Fuzisawa Pharmaceutical Co., Ltd. Process for producing tricyclic compound or salt thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3409922A1 (de) * 1984-03-17 1985-09-26 Bayer Ag, 5090 Leverkusen 1,7-diamino-1,4-dihydro-4-oxo-3-(aza)chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie ihre verwendung bei der bekaempfung bakterieller erkrankungen
US4769492A (en) * 1985-03-13 1988-09-06 Nippon Shokubai Kagaku Kogyo Co., Ltd. Method for production of 2,3,4,5-tetrafluorobenzoic acid
US4782180A (en) * 1985-09-09 1988-11-01 Warner-Lambert Company Process for tetrafluorobenzoic acid
US4689423A (en) * 1986-04-01 1987-08-25 Warner-Lambert Company Process for the preparation of 2,3,4,5-tetrafluorobenzoyl acetates
US4769493A (en) * 1986-08-18 1988-09-06 Sds Biotech K.K. Process for producing tetrafluorophthalic acid
US4864023A (en) * 1986-09-12 1989-09-05 Hoffmann-La Roche Inc. Pyrido(3,2,1-IJ)-1,3,4-benzoxadiazine derivatives
ES2059335T3 (es) * 1986-09-12 1994-11-16 Hoffmann La Roche Derivados de pirido(3,2,1-ij)-1,3,4-benzoxadiazina, procedimiento para su obtencion, preparados farmaceuticos correspondientes y productos intermedios utilizables en el procedimiento.
US4831190A (en) * 1986-12-04 1989-05-16 Ube Industries, Ltd. Trifluorohydroxyaromatic acid and preparation thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60204476A (ja) * 1984-03-29 1985-10-16 株式会社東芝 電子部品の包装容器および包装方法
WO1992015584A1 (en) 1991-02-28 1992-09-17 Fuzisawa Pharmaceutical Co., Ltd. Process for producing tricyclic compound or salt thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Ｌｉｅｂｉｇｓ Ａｎｎａｌｅｎ ｄｅｒ Ｃｈｅｍｉｅ．Ｎｏ．１０，１９８７，Ｐ８７１〜８７９

Also Published As

Publication number Publication date
CN1116849A (zh) 1996-02-14
EP0680482A1 (en) 1995-11-08
ATE151075T1 (de) 1997-04-15
KR100256461B1 (ko) 2000-05-15
EP0680482B1 (en) 1997-04-02
JPH08502756A (ja) 1996-03-26
AU688301B2 (en) 1998-03-12
US5892040A (en) 1999-04-06
DK0680482T3 (da) 1997-05-05
CA2153984C (en) 2008-08-05
WO1994017074A1 (en) 1994-08-04
DE69402412D1 (de) 1997-05-07
NZ261106A (en) 1997-06-24
ZA94433B (en) 1995-07-21
AU5969694A (en) 1994-08-15
CA2153984A1 (en) 1994-08-04
ES2100695T3 (es) 1997-06-16
TW266208B (enExample) 1995-12-21
CN1053907C (zh) 2000-06-28
DE69402412T2 (de) 1997-07-10
GR3023195T3 (en) 1997-07-30

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