DK0680482T3 - Fremgangsmåde til fremstilling af en tricyclisk forbindelse - Google Patents
Fremgangsmåde til fremstilling af en tricyclisk forbindelseInfo
- Publication number
- DK0680482T3 DK0680482T3 DK94905666.7T DK94905666T DK0680482T3 DK 0680482 T3 DK0680482 T3 DK 0680482T3 DK 94905666 T DK94905666 T DK 94905666T DK 0680482 T3 DK0680482 T3 DK 0680482T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- compound
- preparing
- date
- sec
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 3
- 239000007795 chemical reaction product Substances 0.000 abstract 2
- -1 formiate compound Chemical class 0.000 abstract 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 2
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 abstract 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 235000019253 formic acid Nutrition 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
- C07C243/26—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C243/28—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of a saturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP93101031 | 1993-01-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0680482T3 true DK0680482T3 (da) | 1997-05-05 |
Family
ID=8212553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94905666.7T DK0680482T3 (da) | 1993-01-23 | 1994-01-19 | Fremgangsmåde til fremstilling af en tricyclisk forbindelse |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5892040A (da) |
| EP (1) | EP0680482B1 (da) |
| JP (1) | JP2809509B2 (da) |
| KR (1) | KR100256461B1 (da) |
| CN (1) | CN1053907C (da) |
| AT (1) | ATE151075T1 (da) |
| AU (1) | AU688301B2 (da) |
| CA (1) | CA2153984C (da) |
| DE (1) | DE69402412T2 (da) |
| DK (1) | DK0680482T3 (da) |
| ES (1) | ES2100695T3 (da) |
| GR (1) | GR3023195T3 (da) |
| NZ (1) | NZ261106A (da) |
| TW (1) | TW266208B (da) |
| WO (1) | WO1994017074A1 (da) |
| ZA (1) | ZA94433B (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4329600A1 (de) * | 1993-09-02 | 1995-03-09 | Bayer Ag | Pyrido [1,2,3-d,e] [1,3,4] benzoxadiazinderivate |
| CN101020647B (zh) * | 2007-02-14 | 2011-03-30 | 杭州师范学院 | 一种β-环丙胺基丙烯酸(酯)的合成方法 |
| EP2332916A3 (en) | 2009-11-19 | 2011-08-03 | Krka Tovarna Zdravil, D.D., Novo Mesto | A process for a preparation of marbofloxacin and intermediate thereof |
| CN102060860B (zh) * | 2011-01-07 | 2013-04-10 | 宁波美诺华药业股份有限公司 | 一种马波沙星的制备方法 |
| CN102617595A (zh) * | 2012-03-23 | 2012-08-01 | 江西华士药业有限公司 | 氟喹诺酮类抗菌药马波沙星的制备方法 |
| CN107383058B (zh) * | 2017-08-28 | 2019-07-26 | 海门慧聚药业有限公司 | 马波沙星的制备 |
| CN107522718B (zh) * | 2017-09-14 | 2019-11-08 | 浙江国邦药业有限公司 | 一种马波沙星的合成方法 |
| CN114249749B (zh) * | 2022-01-08 | 2024-03-22 | 天象生物药业邢台有限责任公司 | 一种马波沙星甲酸盐的转化方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3409922A1 (de) * | 1984-03-17 | 1985-09-26 | Bayer Ag, 5090 Leverkusen | 1,7-diamino-1,4-dihydro-4-oxo-3-(aza)chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie ihre verwendung bei der bekaempfung bakterieller erkrankungen |
| US4769492A (en) * | 1985-03-13 | 1988-09-06 | Nippon Shokubai Kagaku Kogyo Co., Ltd. | Method for production of 2,3,4,5-tetrafluorobenzoic acid |
| US4782180A (en) * | 1985-09-09 | 1988-11-01 | Warner-Lambert Company | Process for tetrafluorobenzoic acid |
| US4689423A (en) * | 1986-04-01 | 1987-08-25 | Warner-Lambert Company | Process for the preparation of 2,3,4,5-tetrafluorobenzoyl acetates |
| US4769493A (en) * | 1986-08-18 | 1988-09-06 | Sds Biotech K.K. | Process for producing tetrafluorophthalic acid |
| US4864023A (en) * | 1986-09-12 | 1989-09-05 | Hoffmann-La Roche Inc. | Pyrido(3,2,1-IJ)-1,3,4-benzoxadiazine derivatives |
| ES2059335T3 (es) * | 1986-09-12 | 1994-11-16 | Hoffmann La Roche | Derivados de pirido(3,2,1-ij)-1,3,4-benzoxadiazina, procedimiento para su obtencion, preparados farmaceuticos correspondientes y productos intermedios utilizables en el procedimiento. |
| US4831190A (en) * | 1986-12-04 | 1989-05-16 | Ube Industries, Ltd. | Trifluorohydroxyaromatic acid and preparation thereof |
-
1994
- 1994-01-19 WO PCT/EP1994/000147 patent/WO1994017074A1/en active IP Right Grant
- 1994-01-19 KR KR1019950702906A patent/KR100256461B1/ko not_active IP Right Cessation
- 1994-01-19 DE DE69402412T patent/DE69402412T2/de not_active Expired - Lifetime
- 1994-01-19 JP JP6516654A patent/JP2809509B2/ja not_active Expired - Lifetime
- 1994-01-19 DK DK94905666.7T patent/DK0680482T3/da active
- 1994-01-19 NZ NZ261106A patent/NZ261106A/en not_active IP Right Cessation
- 1994-01-19 AU AU59696/94A patent/AU688301B2/en not_active Expired
- 1994-01-19 US US08/492,039 patent/US5892040A/en not_active Expired - Lifetime
- 1994-01-19 EP EP94905666A patent/EP0680482B1/en not_active Expired - Lifetime
- 1994-01-19 CA CA002153984A patent/CA2153984C/en not_active Expired - Lifetime
- 1994-01-19 AT AT94905666T patent/ATE151075T1/de active
- 1994-01-19 CN CN94190968A patent/CN1053907C/zh not_active Expired - Lifetime
- 1994-01-19 ES ES94905666T patent/ES2100695T3/es not_active Expired - Lifetime
- 1994-01-21 ZA ZA94433A patent/ZA94433B/xx unknown
- 1994-07-04 TW TW083106088A patent/TW266208B/zh not_active IP Right Cessation
-
1997
- 1997-04-21 GR GR970400856T patent/GR3023195T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR3023195T3 (en) | 1997-07-30 |
| EP0680482B1 (en) | 1997-04-02 |
| WO1994017074A1 (en) | 1994-08-04 |
| NZ261106A (en) | 1997-06-24 |
| DE69402412T2 (de) | 1997-07-10 |
| TW266208B (da) | 1995-12-21 |
| ES2100695T3 (es) | 1997-06-16 |
| CA2153984C (en) | 2008-08-05 |
| DE69402412D1 (de) | 1997-05-07 |
| ATE151075T1 (de) | 1997-04-15 |
| KR100256461B1 (ko) | 2000-05-15 |
| US5892040A (en) | 1999-04-06 |
| AU5969694A (en) | 1994-08-15 |
| JP2809509B2 (ja) | 1998-10-08 |
| ZA94433B (en) | 1995-07-21 |
| EP0680482A1 (en) | 1995-11-08 |
| JPH08502756A (ja) | 1996-03-26 |
| CN1116849A (zh) | 1996-02-14 |
| CN1053907C (zh) | 2000-06-28 |
| CA2153984A1 (en) | 1994-08-04 |
| AU688301B2 (en) | 1998-03-12 |
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