JP2025508051A - 大うつ病性障害の治療に使用するためのアチカプラントの多形形態 - Google Patents

大うつ病性障害の治療に使用するためのアチカプラントの多形形態 Download PDF

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JP2025508051A
JP2025508051A JP2024553358A JP2024553358A JP2025508051A JP 2025508051 A JP2025508051 A JP 2025508051A JP 2024553358 A JP2024553358 A JP 2024553358A JP 2024553358 A JP2024553358 A JP 2024553358A JP 2025508051 A JP2025508051 A JP 2025508051A
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aticaplant
crystalline form
atikaplant
amorphous
treatment
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Japanese (ja)
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JP2025508051A5 (https=
Inventor
フェルナンデス，フィリップ
シュミット，マーク
ポポワ，ヴァニナ
サヴィッツ，アダム
メルコテ，ラマ
シー． ドレヴェツ，ワイン
ゴパール，シュリハリ
ペンバートン，ダレル
ラジシェティ，チャクラダール
ケジック，イヴァ
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ヤンセン ファーマシューティカルズ，インコーポレーテッド
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Publication of JP2025508051A publication Critical patent/JP2025508051A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2024553358A 2022-03-07 2023-03-06 大うつ病性障害の治療に使用するためのアチカプラントの多形形態 Pending JP2025508051A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263317475P 2022-03-07 2022-03-07
US63/317,475 2022-03-07
PCT/IB2023/052088 WO2023170550A1 (en) 2022-03-07 2023-03-06 Polymorph forms of aticaprant for use in treating major depressive disorder

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JP2025508051A true JP2025508051A (ja) 2025-03-21
JP2025508051A5 JP2025508051A5 (https=) 2026-03-05

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JP2024553358A Pending JP2025508051A (ja) 2022-03-07 2023-03-06 大うつ病性障害の治療に使用するためのアチカプラントの多形形態

Country Status (14)

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US (3) US11998524B2 (https=)
EP (1) EP4489747A1 (https=)
JP (1) JP2025508051A (https=)
KR (1) KR20240156409A (https=)
CN (1) CN119156211A (https=)
AU (1) AU2023232536A1 (https=)
CA (1) CA3254365A1 (https=)
CL (1) CL2024002627A1 (https=)
CO (1) CO2024012158A2 (https=)
IL (1) IL315409A (https=)
JO (1) JOP20240197A1 (https=)
MX (1) MX2024010980A (https=)
TW (1) TW202345796A (https=)
WO (1) WO2023170550A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12161622B2 (en) 2021-05-04 2024-12-10 Janssen Pharmaceuticals, Inc. Compositions and methods for the treatment of depression
EP4489730B1 (en) 2022-03-07 2026-01-21 Janssen Pharmaceuticals, Inc. Compositions comprising aticaprant

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Publication number Publication date
US20250325515A1 (en) 2025-10-23
US20230277499A1 (en) 2023-09-07
CO2024012158A2 (es) 2024-09-30
US11998524B2 (en) 2024-06-04
JOP20240197A1 (ar) 2024-09-05
CL2024002627A1 (es) 2025-01-24
IL315409A (en) 2024-11-01
CN119156211A (zh) 2024-12-17
MX2024010980A (es) 2024-12-06
TW202345796A (zh) 2023-12-01
US20240316003A1 (en) 2024-09-26
CA3254365A1 (en) 2023-09-14
AU2023232536A1 (en) 2024-10-24
KR20240156409A (ko) 2024-10-29
US12171743B2 (en) 2024-12-24
WO2023170550A1 (en) 2023-09-14
EP4489747A1 (en) 2025-01-15

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