|
TWI329105B
(en)
|
2002-02-01 |
2010-08-21 |
Rigel Pharmaceuticals Inc |
2,4-pyrimidinediamine compounds and their uses
|
|
EP1883302A4
(en)
|
2005-05-03 |
2009-05-20 |
Rigel Pharmaceuticals Inc |
JAK KINASE HEMMER AND ITS USE
|
|
MX2009000769A
(es)
|
2006-07-21 |
2009-01-28 |
Novartis Ag |
Compuestos de 2,4-di(arilaminio)-pirimidin-5-carboxamida como inhibidores de cinasas jak.
|
|
SG2014015085A
(en)
*
|
2008-04-16 |
2014-06-27 |
Portola Pharm Inc |
2,6-diamino-pyrimidin-5-yl-carboxamides as syk or jak kinases inhibitors
|
|
EA024109B1
(ru)
*
|
2008-04-16 |
2016-08-31 |
Портола Фармасьютиклз, Инк. |
Ингибиторы протеинкиназ
|
|
SMT202400031T1
(it)
|
2011-04-22 |
2024-03-13 |
Signal Pharm Llc |
Diamminocarbossammide e diamminocarbonitrile pirimidine sostituite, loro composizioni e metodi di trattamento con esse
|
|
WO2013104573A1
(en)
|
2012-01-10 |
2013-07-18 |
F. Hoffmann-La Roche Ag |
Pyridazine amide compounds and their use as syk inhibitors
|
|
UY34807A
(es)
|
2012-05-16 |
2013-12-31 |
Novartis Ag |
Derivados monocíclicos de heteroarilcicloalquil- diamina
|
|
US9040530B2
(en)
|
2012-06-22 |
2015-05-26 |
Portola Pharmaceuticals, Inc. |
1,2,4-triazine-6-carboxamide kinase inhibitors
|
|
MY194668A
(en)
|
2012-11-08 |
2022-12-12 |
Bristol Myers Squibb Co |
Amide-substituted heterocyclic compounds useful as modulators of il-12, il-23 and/or ifn() responses
|
|
US9315494B2
(en)
|
2012-11-08 |
2016-04-19 |
Bristol-Myers Squibb Company |
Alkyl-amide-substituted pyridyl compounds useful as modulators of IL-12, IL-23 and/or IFNα responses
|
|
JP2014198693A
(ja)
|
2013-03-29 |
2014-10-23 |
大鵬薬品工業株式会社 |
免疫疾患の予防及び/又は治療剤
|
|
AR094537A1
(es)
|
2013-11-07 |
2015-08-12 |
Bristol Myers Squibb Co |
COMPUESTOS DE PIRIDILO SUSTITUIDOS CON ALQUILAMIDA ÚTILES COMO MODULADORES DE LAS RESPUESTAS DE IL-12, IL-23 Y/O IFNa
|
|
GB201717260D0
(en)
|
2017-10-20 |
2017-12-06 |
Galapagos Nv |
Novel compounds and pharma ceutical compositions thereof for the treatment of inflammatory disorders
|
|
MX2020005210A
(es)
|
2017-11-21 |
2020-08-20 |
Bristol Myers Squibb Co |
Compuestos de heteroarilo sustituidos con alquilamida de piridinsulfona.
|
|
EP3768667B1
(en)
*
|
2018-03-22 |
2023-04-12 |
Bristol-Myers Squibb Company |
Heterocyclic compounds comprising pyridine useful as modulators of il-12, il-23 and/or ifn alpha responses
|
|
AU2019364336B2
(en)
*
|
2018-10-22 |
2023-11-16 |
Alumis Inc. |
TYK2 inhibitors and uses thereof
|
|
CA3118094A1
(en)
|
2018-10-30 |
2020-05-07 |
Bristol-Myers Squibb Company |
Amide-substituted heterocyclic compounds for the treatment of conditions related to the modulation of il-12, il-23 and/or ifn-alpha
|
|
CN111757878B
(zh)
*
|
2019-01-28 |
2023-07-28 |
江苏豪森药业集团有限公司 |
一种哒嗪类衍生物抑制剂、其制备方法和应用
|
|
CN111484480B
(zh)
*
|
2019-01-29 |
2023-08-11 |
上海翰森生物医药科技有限公司 |
一种多环类衍生物抑制剂、其制备方法和应用
|
|
US20230093099A1
(en)
*
|
2019-04-02 |
2023-03-23 |
Cullgen (Shanghai), Inc. |
Compounds and methods of treating cancers
|
|
WO2021143498A1
(zh)
*
|
2020-01-19 |
2021-07-22 |
苏州科睿思制药有限公司 |
一种Deucravacitinib的晶型及其制备方法和用途
|
|
DK4038063T3
(da)
*
|
2020-03-11 |
2024-05-21 |
Beijing Innocare Pharma Tech Co Ltd |
Heterocykliske forbindelser til inhibering af tyk2-aktiviteter
|
|
WO2021202652A1
(en)
*
|
2020-04-01 |
2021-10-07 |
Eternity Bioscience Inc. |
Tyrosine kinase 2 inhibitors, preparation methods and medicinal uses thereof
|
|
US20230295119A1
(en)
*
|
2020-04-14 |
2023-09-21 |
Gossamer Bio Services, Inc. |
Substituted pyridines for the treatment of inflammatory diseases
|
|
CN113563309B
(zh)
*
|
2020-04-28 |
2024-12-13 |
浙江海正药业股份有限公司 |
吡啶类衍生物及其制备方法和用途
|
|
US20220002267A1
(en)
|
2020-06-24 |
2022-01-06 |
Eternity Bioscience Inc. |
Tyrosine kinase 2 inhibitors, preparation methods and medicinal uses thereof
|
|
CN113968846A
(zh)
|
2020-07-24 |
2022-01-25 |
上海翰森生物医药科技有限公司 |
一种哒嗪类衍生物的盐、晶型及其制备方法和应用
|
|
CN116283954A
(zh)
*
|
2020-12-02 |
2023-06-23 |
深圳微芯生物科技股份有限公司 |
羟肟酸酯化合物、其制备方法及其应用
|
|
CN115197196B
(zh)
*
|
2021-04-06 |
2024-06-18 |
扬子江药业集团有限公司 |
Tyk2抑制剂及其用途
|
|
CN116888125B
(zh)
*
|
2021-04-07 |
2024-04-12 |
上海齐鲁制药研究中心有限公司 |
Tyk2抑制剂及其用途
|
|
WO2022219380A1
(en)
|
2021-04-16 |
2022-10-20 |
Sri Lanka Institute Of Information Technology |
A method of making silver-iron titanate nanoparticles and uses thereof
|
|
CN115466257A
(zh)
*
|
2021-06-11 |
2022-12-13 |
爱科诺生物医药(香港)有限公司 |
具有tyk2抑制活性的化合物,包含其的药物组合物,及其应用
|