JP2022505525A5 - - Google Patents
Info
- Publication number
- JP2022505525A5 JP2022505525A5 JP2021521800A JP2021521800A JP2022505525A5 JP 2022505525 A5 JP2022505525 A5 JP 2022505525A5 JP 2021521800 A JP2021521800 A JP 2021521800A JP 2021521800 A JP2021521800 A JP 2021521800A JP 2022505525 A5 JP2022505525 A5 JP 2022505525A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- alkyl
- groups
- aryl
- ring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (25)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862749730P | 2018-10-24 | 2018-10-24 | |
| US201862749712P | 2018-10-24 | 2018-10-24 | |
| US201862749725P | 2018-10-24 | 2018-10-24 | |
| US62/749,725 | 2018-10-24 | ||
| US62/749,712 | 2018-10-24 | ||
| US62/749,730 | 2018-10-24 | ||
| US201862751301P | 2018-10-26 | 2018-10-26 | |
| US201862751380P | 2018-10-26 | 2018-10-26 | |
| US201862751386P | 2018-10-26 | 2018-10-26 | |
| US62/751,380 | 2018-10-26 | ||
| US62/751,301 | 2018-10-26 | ||
| US62/751,386 | 2018-10-26 | ||
| US201962801930P | 2019-02-06 | 2019-02-06 | |
| US62/801,930 | 2019-02-06 | ||
| US201962802637P | 2019-02-07 | 2019-02-07 | |
| US201962802654P | 2019-02-07 | 2019-02-07 | |
| US62/802,654 | 2019-02-07 | ||
| US62/802,637 | 2019-02-07 | ||
| US201962812794P | 2019-03-01 | 2019-03-01 | |
| US201962812813P | 2019-03-01 | 2019-03-01 | |
| US201962812517P | 2019-03-01 | 2019-03-01 | |
| US62/812,794 | 2019-03-01 | ||
| US62/812,813 | 2019-03-01 | ||
| US62/812,517 | 2019-03-01 | ||
| PCT/US2019/057682 WO2020086732A1 (en) | 2018-10-24 | 2019-10-23 | Compounds and compositions for treating conditions associated with nlrp activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022505525A JP2022505525A (ja) | 2022-01-14 |
| JP2022505525A5 true JP2022505525A5 (https=) | 2022-10-24 |
Family
ID=68583498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021521800A Pending JP2022505525A (ja) | 2018-10-24 | 2019-10-23 | Ｎｌｒｐ活性に関連する状態を治療するための化合物及び組成物 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20230011652A1 (https=) |
| EP (1) | EP3870565A1 (https=) |
| JP (1) | JP2022505525A (https=) |
| CN (1) | CN113056451A (https=) |
| WO (1) | WO2020086732A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3047336A1 (en) | 2017-01-23 | 2018-07-26 | Jecure Therapeutics, Inc. | Chemical compounds as inhibitors of interleukin-1 activity |
| MX2020001776A (es) | 2017-08-15 | 2020-03-24 | Inflazome Ltd | Sulfonilureas y sulfoniltioureas como inhibidores de nlrp3. |
| US11542255B2 (en) | 2017-08-15 | 2023-01-03 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors |
| WO2019034693A1 (en) | 2017-08-15 | 2019-02-21 | Inflazome Limited | SULFONYLURATES AND SULFONYLTHIOURES AS INHIBITORS OF NLRP3 |
| KR20200087759A (ko) | 2017-11-09 | 2020-07-21 | 인플라좀 리미티드 | 신규한 설폰아마이드 카복스아마이드 화합물 |
| US12221434B2 (en) | 2017-11-09 | 2025-02-11 | Inflazome Limited | Sulfonamide carboxamide compounds |
| EP3759077A1 (en) | 2018-03-02 | 2021-01-06 | Inflazome Limited | Novel compounds |
| SG11202012159TA (en) | 2018-07-20 | 2021-01-28 | Hoffmann La Roche | Sulfonylurea compounds as inhibitors of interleukin-1 activity |
| EP3823974A1 (en) | 2018-07-20 | 2021-05-26 | F. Hoffmann-La Roche AG | Sulfonimidamide compounds as inhibitors of interleukin-1 activity |
| US12187702B2 (en) | 2018-08-15 | 2025-01-07 | Inflazome Limited | Sulfonamideurea compounds |
| JP7595642B2 (ja) | 2019-07-17 | 2024-12-06 | ズーマゲン バイオサイエンシーズ エルティーディー | Ｎｌｒｐ３モジュレーター |
| AU2020312800B2 (en) * | 2019-07-17 | 2026-04-23 | Zomagen Biosciences Ltd | N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-4,5,6,7-tetrahydrobenzofuran -2-sulfonamide derivatives and related compounds as NLPR3 modulators for the treatment of multiple sclerosis (ms) |
| KR20220154165A (ko) | 2020-03-16 | 2022-11-21 | 조마젠 바이오사이언시즈 엘티디 | Nlrp3 조절제 |
| CN114516878B (zh) * | 2020-11-20 | 2024-02-02 | 上海拓界生物医药科技有限公司 | 三环化合物及其医药用途 |
| CN114539256B (zh) * | 2020-11-20 | 2024-02-02 | 上海拓界生物医药科技有限公司 | 三环化合物及其医药用途 |
| JP7825294B2 (ja) * | 2021-02-10 | 2026-03-06 | ハンジョウ イノゲート ファーマ カンパニー リミテッド | Ｎｌｒｐ３阻害剤としての化合物 |
| US11932630B2 (en) | 2021-04-16 | 2024-03-19 | Novartis Ag | Heteroaryl aminopropanol derivatives |
| TW202333678A (zh) * | 2021-12-22 | 2023-09-01 | 大陸商瑞石生物醫藥有限公司 | 一種磺醯脲類化合物 |
| CN116804018A (zh) * | 2022-03-25 | 2023-09-26 | 成都百裕制药股份有限公司 | 酰胺衍生物及其制备方法和在医药上的应用 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4671817A (en) | 1985-04-23 | 1987-06-09 | E. I. Du Pont De Nemours And Company | Herbicidal pyrazole sulfonamides |
| US4678498A (en) | 1985-06-12 | 1987-07-07 | E. I. Du Pont De Nemours And Company | Herbicidal sulfonamides |
| PH25866A (en) | 1986-03-20 | 1991-12-02 | Takeda Chemical Industries Ltd | Sulfonylurea compounds and their herbicides |
| US4927453A (en) | 1986-10-17 | 1990-05-22 | E. I. Du Pont De Nemours And Company | Herbicidal sulfonamides |
| EP0318620A1 (en) | 1987-12-04 | 1989-06-07 | E.I. Du Pont De Nemours And Company | Herbicidal sulfonamides |
| CA2074163A1 (en) | 1990-01-22 | 1991-07-23 | William Thomas Zimmerman | Herbicidal sulfonylureas |
| US5169860A (en) * | 1992-03-13 | 1992-12-08 | Eli Lilly And Company | Antitumor compositions and methods of treatment |
| AU723895B2 (en) * | 1997-01-29 | 2000-09-07 | Pfizer Inc. | Sulfonyl urea derivatives and their use in the control of interleukin-1 activity |
| WO2001019390A1 (en) * | 1999-09-14 | 2001-03-22 | Pfizer Products Inc. | Combination treatment with il-1ra and diaryl sulphonyl urea compounds |
| US20030189215A1 (en) | 2002-04-09 | 2003-10-09 | Jong-Lam Lee | Method of fabricating vertical structure leds |
| AR052900A1 (es) * | 2005-02-11 | 2007-04-11 | Astrazeneca Ab | Derivados de tiazol, un metodo para su preparacion, composiciones farmaceuticas que los contienen y su uso en la elaboracion de medicamentos para el tratamiento de enfermedades mediadas por ece-1 |
| DK200600313A (da) | 2006-03-03 | 2006-03-13 | Novo Nordisk As | Treating type 2 diabetes or metabolic syndrome with an interleukin 1beta inhibitor or an interleukin 1beta synthesis or release inhibitor |
| US7973051B2 (en) * | 2007-11-30 | 2011-07-05 | Hoffman-La Roche Inc. | Aminothiazoles as FBPase inhibitors for diabetes |
| KR102727059B1 (ko) * | 2015-02-16 | 2024-11-05 | 더 유니버서티 어브 퀸슬랜드 | 설포닐우레아와 관련 화합물 및 그 용도 |
| US11597706B2 (en) * | 2016-04-18 | 2023-03-07 | Novartis Ag | Compounds and compositions for treating conditions associated with NLRP activity |
| EP3272739A1 (en) * | 2016-07-20 | 2018-01-24 | NodThera Limited | Sulfonyl urea derivatives and their use in the control of interleukin-1 activity |
| CA3047336A1 (en) | 2017-01-23 | 2018-07-26 | Jecure Therapeutics, Inc. | Chemical compounds as inhibitors of interleukin-1 activity |
| US11370776B2 (en) | 2017-07-07 | 2022-06-28 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors |
| US11518739B2 (en) | 2017-08-15 | 2022-12-06 | Inflazome Limited | Sulfonamide carboxamide compounds |
| EP3668861A1 (en) | 2017-08-15 | 2020-06-24 | Inflazome Limited | Novel sulfonamide carboxamide compounds |
| US11542255B2 (en) | 2017-08-15 | 2023-01-03 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors |
| MX2020001776A (es) * | 2017-08-15 | 2020-03-24 | Inflazome Ltd | Sulfonilureas y sulfoniltioureas como inhibidores de nlrp3. |
| JP2020531448A (ja) | 2017-08-15 | 2020-11-05 | インフレイゾーム リミテッド | 新規なスルホンアミドカルボキサミド化合物 |
| WO2019034693A1 (en) | 2017-08-15 | 2019-02-21 | Inflazome Limited | SULFONYLURATES AND SULFONYLTHIOURES AS INHIBITORS OF NLRP3 |
| EP3668862A1 (en) | 2017-08-15 | 2020-06-24 | Inflazome Limited | Novel sulfonamide carboxamide compounds |
-
2019
- 2019-10-23 CN CN201980074404.6A patent/CN113056451A/zh active Pending
- 2019-10-23 WO PCT/US2019/057682 patent/WO2020086732A1/en not_active Ceased
- 2019-10-23 EP EP19805434.8A patent/EP3870565A1/en not_active Withdrawn
- 2019-10-23 US US17/287,834 patent/US20230011652A1/en not_active Abandoned
- 2019-10-23 JP JP2021521800A patent/JP2022505525A/ja active Pending
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