JP2022507506A5 - - Google Patents

Info

Publication number
JP2022507506A5
JP2022507506A5 JP2021526492A JP2021526492A JP2022507506A5 JP 2022507506 A5 JP2022507506 A5 JP 2022507506A5 JP 2021526492 A JP2021526492 A JP 2021526492A JP 2021526492 A JP2021526492 A JP 2021526492A JP 2022507506 A5 JP2022507506 A5 JP 2022507506A5
Authority
JP
Japan
Application number
JP2021526492A
Other languages
Japanese (ja)
Other versions
JPWO2020102576A5 (https=
JP2022507506A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/061533 external-priority patent/WO2020102576A1/en
Publication of JP2022507506A publication Critical patent/JP2022507506A/ja
Publication of JP2022507506A5 publication Critical patent/JP2022507506A5/ja
Publication of JPWO2020102576A5 publication Critical patent/JPWO2020102576A5/ja
Pending legal-status Critical Current

Links

JP2021526492A 2018-11-16 2019-11-14 Nlrp活性に関連する状態を治療するための化合物及び組成物 Pending JP2022507506A (ja)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US201862768804P 2018-11-16 2018-11-16
US62/768,804 2018-11-16
US201862769165P 2018-11-19 2018-11-19
US201862769151P 2018-11-19 2018-11-19
US62/769,165 2018-11-19
US62/769,151 2018-11-19
US201962795913P 2019-01-23 2019-01-23
US62/795,913 2019-01-23
US201962796356P 2019-01-24 2019-01-24
US201962796361P 2019-01-24 2019-01-24
US62/796,361 2019-01-24
US62/796,356 2019-01-24
US201962802621P 2019-02-07 2019-02-07
US62/802,621 2019-02-07
US201962895954P 2019-09-04 2019-09-04
US62/895,954 2019-09-04
PCT/US2019/061533 WO2020102576A1 (en) 2018-11-16 2019-11-14 Compounds and compositions for treating conditions associated with nlrp activity

Publications (3)

Publication Number Publication Date
JP2022507506A JP2022507506A (ja) 2022-01-18
JP2022507506A5 true JP2022507506A5 (https=) 2022-11-21
JPWO2020102576A5 JPWO2020102576A5 (https=) 2022-11-21

Family

ID=68808610

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021526492A Pending JP2022507506A (ja) 2018-11-16 2019-11-14 Nlrp活性に関連する状態を治療するための化合物及び組成物

Country Status (6)

Country Link
US (1) US20230051589A1 (https=)
EP (1) EP3880659B1 (https=)
JP (1) JP2022507506A (https=)
CN (1) CN113286784A (https=)
TW (1) TW202033504A (https=)
WO (1) WO2020102576A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3105521A1 (en) 2018-07-20 2020-01-23 F. Hoffmann-La Roche Ag Sulfonimidamide compounds as inhibitors of interleukin-1 activity
PH12022551767A1 (en) * 2020-01-22 2023-11-29 Hoffmann La Roche Sulfonimidamide compounds as nlrp3 modulators
EP3984535A1 (en) * 2020-10-16 2022-04-20 Albert-Ludwigs-Universität Freiburg Nlrp3 activators for use in the treatment of infectious diseases or cancer by activating nlrp3 inflammasome
CN114539256B (zh) * 2020-11-20 2024-02-02 上海拓界生物医药科技有限公司 三环化合物及其医药用途
CN117279903A (zh) * 2021-02-10 2023-12-22 杭州英创医药科技有限公司 作为nlrp3抑制剂的化合物
US11932630B2 (en) 2021-04-16 2024-03-19 Novartis Ag Heteroaryl aminopropanol derivatives
CN118302415A (zh) * 2021-12-03 2024-07-05 辰欣药业股份有限公司 二甲基亚磺酰亚胺衍生物的制备方法
CN116804018A (zh) * 2022-03-25 2023-09-26 成都百裕制药股份有限公司 酰胺衍生物及其制备方法和在医药上的应用
CN114989058B (zh) * 2022-06-02 2024-04-16 中国科学院成都生物研究所 一种手性氯代砜亚胺类化合物及其衍生物的制备方法
EP4561574A1 (en) * 2022-07-27 2025-06-04 Novartis AG Dosing regimen for a nlrp3 inhibitor
CN115961298B (zh) * 2022-12-31 2024-10-01 广西师范大学 一种电化学介导乙烯基苯胺与醇合成2,3-二烷氧基取代吲哚啉化合物、合成方法及应用
TW202502747A (zh) * 2023-03-17 2025-01-16 美商凡特斯治療美國公司 用於抑制nlrp3之醯胺衍生物及其用途
WO2025153532A1 (en) 2024-01-16 2025-07-24 NodThera Limited Nlrp3 inhibitors and glp-1 agonists combination therapies

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3259253T1 (sl) * 2015-02-16 2020-07-31 The University Of Queensland Sulfonilsečnine in sorodne spojine ter njihova uporaba
FR3046933B1 (fr) * 2016-01-25 2018-03-02 Galderma Research & Development Inhibiteurs nlrp3 pour le traitement des pathologies cutanees inflammatoires
WO2018225018A1 (en) * 2017-06-09 2018-12-13 Cadila Healthcare Limited Novel substituted sulfoximine compounds
ES2988798T3 (es) * 2017-07-24 2024-11-21 Novartis Ag Compuestos y composiciones para el tratamiento de afecciones asociadas a la actividad de NLRP
EP3692020A1 (en) * 2017-10-03 2020-08-12 Inflazome Limited Novel compounds
CA3105521A1 (en) * 2018-07-20 2020-01-23 F. Hoffmann-La Roche Ag Sulfonimidamide compounds as inhibitors of interleukin-1 activity

Similar Documents

Publication Publication Date Title
BR112021017339A2 (https=)
BR112021018450A2 (https=)
BR112021017637A2 (https=)
JP2022507506A5 (https=)
BR112021017892A2 (https=)
BR112021017782A2 (https=)
BR112021016821A2 (https=)
BR112021017939A2 (https=)
BR112021017738A2 (https=)
BR112021016996A2 (https=)
BR112021008711A2 (https=)
BR112021017728A2 (https=)
BR112021013944A2 (https=)
BR112021018452A2 (https=)
BR112021017703A2 (https=)
BR112021018102A2 (https=)
BR112021017732A2 (https=)
BR112021017234A2 (https=)
BR112021017355A2 (https=)
BR112021018168A2 (https=)
BR112021018093A2 (https=)
BR112021017173A2 (https=)
BR112021017083A2 (https=)
BR112021015080A2 (https=)
BR112021012348A2 (https=)