JP2022553376A5 - - Google Patents
Info
- Publication number
- JP2022553376A5 JP2022553376A5 JP2022523864A JP2022523864A JP2022553376A5 JP 2022553376 A5 JP2022553376 A5 JP 2022553376A5 JP 2022523864 A JP2022523864 A JP 2022523864A JP 2022523864 A JP2022523864 A JP 2022523864A JP 2022553376 A5 JP2022553376 A5 JP 2022553376A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- independently selected
- cycloalkyl
- halo
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962926072P | 2019-10-25 | 2019-10-25 | |
| US62/926,072 | 2019-10-25 | ||
| PCT/US2020/056873 WO2021081211A1 (en) | 2019-10-25 | 2020-10-22 | Mettl3 modulators |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022553376A JP2022553376A (ja) | 2022-12-22 |
| JP2022553376A5 true JP2022553376A5 (https=) | 2023-10-31 |
Family
ID=73288712
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022523864A Pending JP2022553376A (ja) | 2019-10-25 | 2020-10-22 | Ｍｅｔｔｌ３モジュレーター |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20220372040A1 (https=) |
| EP (1) | EP4048670A1 (https=) |
| JP (1) | JP2022553376A (https=) |
| CN (1) | CN115279756A (https=) |
| AU (1) | AU2020370281A1 (https=) |
| WO (1) | WO2021081211A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20230098872A1 (en) * | 2021-03-26 | 2023-03-30 | Cedilla Therapeutics, Inc. | Tead inhibitors and uses thereof |
| CN117157297A (zh) * | 2021-07-20 | 2023-12-01 | 上海齐鲁制药研究中心有限公司 | Prmt5抑制剂 |
| CN116283993B (zh) * | 2021-12-20 | 2024-05-03 | 艾立康药业股份有限公司 | 一种嘧啶类化合物及其制备方法和应用 |
| CN118660890A (zh) * | 2022-02-11 | 2024-09-17 | 西藏海思科制药有限公司 | 一种mettl3抑制剂及组合物及其在医药上的应用 |
| KR102866487B1 (ko) | 2023-01-06 | 2025-10-01 | 연세대학교 산학협력단 | 새로운 인돌리진-피롤로피리미딘 하이브리드 유도체 제조방법 및 이를 포함하는 항암제 조성물 |
| CN120731203A (zh) | 2023-01-20 | 2025-09-30 | 艾匹克治疗公司 | 作为mettl3抑制剂的哌啶衍生物 |
| AU2024244637A1 (en) | 2023-03-30 | 2025-10-16 | Aqemia | Novel mettl3 inhibitors and use thereof in therapy |
| US12168662B1 (en) | 2023-12-15 | 2024-12-17 | King Faisal University | Pyrido[4′,3′:4,5]pyrrolo[2,3-c][2,7]naphthyridines compounds as CK2 inhibitors |
| GB202407738D0 (en) * | 2024-05-31 | 2024-07-17 | Storm Therapeutics Ltd | Inhibitory compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4938949A (en) | 1988-09-12 | 1990-07-03 | University Of New York | Treatment of damaged bone marrow and dosage units therefor |
| US5869485A (en) * | 1994-09-29 | 1999-02-09 | Novartis Finance Corp. | Pyrrolo 2,3-d!pyrimidines and their use |
| JP2009528996A (ja) * | 2006-02-24 | 2009-08-13 | インダストリアル リサーチ リミテッド | ヌクレオシドホスホリラーゼ及びヌクレオシダーゼの阻害剤を用いて疾患を処置する方法 |
| SMT202200396T1 (it) * | 2017-12-13 | 2022-11-18 | Lupin Ltd | Composti eterociclici biciclici sostituiti come inibitori di prmt5 |
| EP3589745A1 (en) * | 2018-04-11 | 2020-01-08 | Chemestmed Ltd. | A method of modulating the rna methylation |
-
2020
- 2020-10-22 US US17/770,714 patent/US20220372040A1/en not_active Abandoned
- 2020-10-22 AU AU2020370281A patent/AU2020370281A1/en not_active Abandoned
- 2020-10-22 EP EP20804406.5A patent/EP4048670A1/en not_active Withdrawn
- 2020-10-22 WO PCT/US2020/056873 patent/WO2021081211A1/en not_active Ceased
- 2020-10-22 CN CN202080086304.8A patent/CN115279756A/zh active Pending
- 2020-10-22 JP JP2022523864A patent/JP2022553376A/ja active Pending
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