JP2022510925A5 - - Google Patents
Info
- Publication number
- JP2022510925A5 JP2022510925A5 JP2021530299A JP2021530299A JP2022510925A5 JP 2022510925 A5 JP2022510925 A5 JP 2022510925A5 JP 2021530299 A JP2021530299 A JP 2021530299A JP 2021530299 A JP2021530299 A JP 2021530299A JP 2022510925 A5 JP2022510925 A5 JP 2022510925A5
- Authority
- JP
- Japan
- Prior art keywords
- pyrazole
- amino
- benzamide
- pharmaceutically acceptable
- acceptable form
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024038370A JP7802106B2 (ja) | 2018-12-14 | 2024-03-12 | ピラゾリル－アミノ－ピリミジニル誘導体のベンズアミド、およびその組成物ならびに方法 |
| JP2024038369A JP7802105B2 (ja) | 2018-12-14 | 2024-03-12 | ピラゾリル－アミノ－ピリミジニル誘導体のベンズアミド、およびその組成物ならびに方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2018/121165 | 2018-12-14 | ||
| PCT/CN2018/121165 WO2020118683A1 (en) | 2018-12-14 | 2018-12-14 | Benzamides of pyrazolyl-amino-pyrimidinyl derivatives, and compositions and methods thereof |
| PCT/CN2019/125552 WO2020119819A1 (en) | 2018-12-14 | 2019-12-16 | Benzamides of pyrazolyl-amino-pyrimidinyl derivatives, and compositions and methods thereof |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024038370A Division JP7802106B2 (ja) | 2018-12-14 | 2024-03-12 | ピラゾリル－アミノ－ピリミジニル誘導体のベンズアミド、およびその組成物ならびに方法 |
| JP2024038369A Division JP7802105B2 (ja) | 2018-12-14 | 2024-03-12 | ピラゾリル－アミノ－ピリミジニル誘導体のベンズアミド、およびその組成物ならびに方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022510925A JP2022510925A (ja) | 2022-01-28 |
| JP2022510925A5 true JP2022510925A5 (https=) | 2022-11-04 |
| JP7459094B2 JP7459094B2 (ja) | 2024-04-01 |
Family
ID=71076270
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021530299A Active JP7459094B2 (ja) | 2018-12-14 | 2019-12-16 | ピラゾリル－アミノ－ピリミジニル誘導体のベンズアミド、およびその組成物ならびに方法 |
| JP2024038370A Active JP7802106B2 (ja) | 2018-12-14 | 2024-03-12 | ピラゾリル－アミノ－ピリミジニル誘導体のベンズアミド、およびその組成物ならびに方法 |
| JP2024038369A Active JP7802105B2 (ja) | 2018-12-14 | 2024-03-12 | ピラゾリル－アミノ－ピリミジニル誘導体のベンズアミド、およびその組成物ならびに方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024038370A Active JP7802106B2 (ja) | 2018-12-14 | 2024-03-12 | ピラゾリル－アミノ－ピリミジニル誘導体のベンズアミド、およびその組成物ならびに方法 |
| JP2024038369A Active JP7802105B2 (ja) | 2018-12-14 | 2024-03-12 | ピラゾリル－アミノ－ピリミジニル誘導体のベンズアミド、およびその組成物ならびに方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (6) | US12421213B2 (https=) |
| EP (1) | EP3877381A4 (https=) |
| JP (3) | JP7459094B2 (https=) |
| KR (2) | KR102881668B1 (https=) |
| CN (7) | CN119118999A (https=) |
| AU (3) | AU2019399939B2 (https=) |
| BR (1) | BR112021011147A2 (https=) |
| CA (3) | CA3230071A1 (https=) |
| EA (1) | EA202191188A1 (https=) |
| IL (3) | IL314084A (https=) |
| MX (3) | MX2021006866A (https=) |
| SG (1) | SG11202105730TA (https=) |
| TW (3) | TWI889397B (https=) |
| WO (2) | WO2020118683A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110627775B (zh) * | 2019-10-24 | 2026-01-30 | 特科罗生物科技(成都)有限公司 | 一种小分子化合物 |
| TW202204333A (zh) | 2020-04-08 | 2022-02-01 | 美商阿吉歐斯製藥公司 | Menin抑制劑及治療癌症之使用方法 |
| CN112661655B (zh) * | 2020-12-29 | 2022-02-18 | 江苏云朴医药新材料科技有限公司 | 一种1-氨甲基-1-环丙醇类化合物及其合成方法 |
| CA3263043A1 (en) * | 2022-08-22 | 2024-02-29 | Hangzhou Highlightll Pharmaceutical Co., Ltd | JAK1/JAK2/TYK2 INHIBITORS FOR THE TOPICAL TREATMENT OF DERMATOLOGICAL DISEASES |
| CN115572269B (zh) * | 2022-10-08 | 2024-05-17 | 广州大学 | 一种n-三氟异丙基唑类和吲哚化合物及其制备方法 |
| WO2023151724A1 (zh) | 2023-05-19 | 2023-08-17 | 凌科药业(杭州)有限公司 | 一种吡唑基-氨基-嘧啶基衍生物的晶型、制备方法及应用 |
| CN116751191B (zh) * | 2023-05-19 | 2025-09-16 | 凌科药业(杭州)有限公司 | 一种吡唑基-氨基-嘧啶基衍生物的晶型、制备方法及应用 |
| WO2024239282A1 (zh) * | 2023-05-24 | 2024-11-28 | 凌科药业(杭州)有限公司 | 一种药物组合物、外用制剂及其制备方法、应用 |
| CN116983312B (zh) * | 2023-05-24 | 2024-07-05 | 凌科药业(杭州)有限公司 | 一种药物组合物、外用制剂及其制备方法、应用 |
| WO2025157231A1 (zh) * | 2024-01-26 | 2025-07-31 | 凌科药业(杭州)有限公司 | 一种吡唑基-氨基-嘧啶基衍生物的苯甲酰胺的晶型、制备方法及应用 |
| CN120917009A (zh) * | 2024-01-26 | 2025-11-07 | 凌科药业(杭州)有限公司 | 一种吡唑基-氨基-嘧啶基衍生物的苯甲酰胺的晶型、制备方法及应用 |
| WO2025256636A1 (zh) * | 2024-06-13 | 2025-12-18 | 凌科药业(杭州)有限公司 | 含氮化合物及其制备方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4911920A (en) | 1986-07-30 | 1990-03-27 | Alcon Laboratories, Inc. | Sustained release, comfort formulation for glaucoma therapy |
| FR2588189B1 (fr) | 1985-10-03 | 1988-12-02 | Merck Sharp & Dohme | Composition pharmaceutique de type a transition de phase liquide-gel |
| JP2594486B2 (ja) | 1991-01-15 | 1997-03-26 | アルコン ラボラトリーズ インコーポレイテッド | 局所的眼薬組成物 |
| US5212162A (en) | 1991-03-27 | 1993-05-18 | Alcon Laboratories, Inc. | Use of combinations gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions |
| WO2007005643A2 (en) | 2005-07-01 | 2007-01-11 | Concert Pharmaceuticals Inc. | Novel aryloxyphenylpropanamines |
| WO2007005644A2 (en) | 2005-07-01 | 2007-01-11 | Concert Pharmaceuticals Inc. | Novel aryloxypropanamines |
| AU2006275702A1 (en) | 2005-07-29 | 2007-02-08 | Concert Pharmaceuticals Inc. | Novel pharmaceutical compounds |
| KR101380190B1 (ko) | 2005-07-29 | 2014-04-11 | 콘서트 파마슈티컬즈, 인크. | 벤조 〔ｄ〕〔１,３〕―디옥솔 유도체 |
| JP2010519174A (ja) * | 2006-09-18 | 2010-06-03 | バーテックス ファーマシューティカルズ インコーポレイテッド | ｃ−Ｍｅｔの複素環阻害薬およびその使用方法 |
| WO2009017838A2 (en) * | 2007-08-01 | 2009-02-05 | Exelixis, Inc. | Combinations of jak-2 inhibitors and other agents |
| UA104849C2 (uk) * | 2007-11-16 | 2014-03-25 | Інсайт Корпорейшн | 4-піразоліл-n-арилпіримідин-2-аміни і 4-піразоліл-n-гетероарилпіримідин-2-аміни як інгібітори кіназ janus |
| JP2014500254A (ja) | 2010-11-09 | 2014-01-09 | セルゾーム リミティッド | Ｔｙｋ２阻害剤としてのピリジン化合物およびそのアザ類似体 |
| WO2012143320A1 (en) * | 2011-04-18 | 2012-10-26 | Cellzome Limited | (7h-pyrrolo[2,3-d]pyrimidin-2-yl)amine compounds as jak3 inhibitors |
| EP2736901A1 (en) * | 2011-07-28 | 2014-06-04 | Cellzome Limited | Heterocyclyl pyrimidine analogues as jak inhibitors |
| DE102011112978A1 (de) * | 2011-09-09 | 2013-03-14 | Merck Patent Gmbh | Benzonitrilderivate |
| KR101361149B1 (ko) * | 2012-07-17 | 2014-02-24 | 전남대학교산학협력단 | 가뭄 스트레스 저항성 관련 유전자 및 형질전환 식물체 |
| AU2014362231B2 (en) * | 2013-12-11 | 2019-04-04 | Biogen Ma Inc. | Biaryl compounds useful for the treatment of human diseases in oncology, neurology and immunology |
| CN106349224A (zh) * | 2016-08-03 | 2017-01-25 | 山东大学 | 一种含有4‑氨基‑(1h)‑吡唑结构的jak激酶抑制剂及其制备方法和应用 |
| CN108864057B (zh) * | 2017-05-16 | 2020-03-31 | 山东大学 | 含有4-氨基吡唑结构的jak与hdac双靶点抑制剂及其制备方法和应用 |
| WO2020206588A1 (en) * | 2019-04-08 | 2020-10-15 | Lynk Pharmaceuticals Co., Ltd. | Benzethers and anilines of pyrazolyl-amino-pyrimidinyl derivatives, and compositions and methods thereof |
| CN110330484B (zh) * | 2019-07-18 | 2022-08-26 | 中国药科大学 | 取代类苯基嘧啶衍生物作为jak激酶抑制剂或其可药用的盐、制备方法及用途 |
| CN110627775B (zh) * | 2019-10-24 | 2026-01-30 | 特科罗生物科技(成都)有限公司 | 一种小分子化合物 |
-
2018
- 2018-12-14 WO PCT/CN2018/121165 patent/WO2020118683A1/en not_active Ceased
-
2019
- 2019-12-13 TW TW113122616A patent/TWI889397B/zh active
- 2019-12-13 TW TW113122615A patent/TWI889396B/zh active
- 2019-12-13 TW TW108145807A patent/TWI866940B/zh active
- 2019-12-16 CN CN202411028139.7A patent/CN119118999A/zh active Pending
- 2019-12-16 KR KR1020217019621A patent/KR102881668B1/ko active Active
- 2019-12-16 AU AU2019399939A patent/AU2019399939B2/en active Active
- 2019-12-16 MX MX2021006866A patent/MX2021006866A/es unknown
- 2019-12-16 CN CN201980076141.2A patent/CN113227074B/zh active Active
- 2019-12-16 IL IL314084A patent/IL314084A/en unknown
- 2019-12-16 CA CA3230071A patent/CA3230071A1/en active Pending
- 2019-12-16 BR BR112021011147-6A patent/BR112021011147A2/pt unknown
- 2019-12-16 CN CN202411028121.7A patent/CN118955477A/zh active Pending
- 2019-12-16 CN CN202411028131.0A patent/CN118903142A/zh active Pending
- 2019-12-16 IL IL314086A patent/IL314086A/en unknown
- 2019-12-16 EP EP19896790.3A patent/EP3877381A4/en active Pending
- 2019-12-16 KR KR1020257036502A patent/KR20250162926A/ko active Pending
- 2019-12-16 EA EA202191188A patent/EA202191188A1/ru unknown
- 2019-12-16 CA CA3230060A patent/CA3230060A1/en active Pending
- 2019-12-16 IL IL283968A patent/IL283968B2/en unknown
- 2019-12-16 CN CN202411028128.9A patent/CN118903141A/zh active Pending
- 2019-12-16 CN CN202410365633.6A patent/CN118290403A/zh active Pending
- 2019-12-16 WO PCT/CN2019/125552 patent/WO2020119819A1/en not_active Ceased
- 2019-12-16 JP JP2021530299A patent/JP7459094B2/ja active Active
- 2019-12-16 SG SG11202105730TA patent/SG11202105730TA/en unknown
- 2019-12-16 CN CN202410365639.3A patent/CN118388457A/zh active Pending
- 2019-12-16 CA CA3122872A patent/CA3122872A1/en active Pending
-
2021
- 2021-06-10 MX MX2024005744A patent/MX2024005744A/es unknown
- 2021-06-10 MX MX2024005747A patent/MX2024005747A/es unknown
-
2022
- 2022-03-01 US US17/684,030 patent/US12421213B2/en active Active
- 2022-03-01 US US17/684,164 patent/US12595253B2/en active Active
-
2023
- 2023-09-10 US US18/244,281 patent/US11981663B2/en active Active
- 2023-09-10 US US18/244,276 patent/US12030870B2/en active Active
- 2023-09-24 US US18/372,115 patent/US12098142B2/en active Active
-
2024
- 2024-02-21 AU AU2024201128A patent/AU2024201128B2/en active Active
- 2024-02-21 AU AU2024201125A patent/AU2024201125B2/en active Active
- 2024-03-12 JP JP2024038370A patent/JP7802106B2/ja active Active
- 2024-03-12 JP JP2024038369A patent/JP7802105B2/ja active Active
- 2024-08-15 US US18/805,713 patent/US20250115586A1/en active Pending
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