TWI889397B - 吡唑基-氨基-嘧啶基衍生物的苯甲醯胺及其組合物和方法 - Google Patents

吡唑基-氨基-嘧啶基衍生物的苯甲醯胺及其組合物和方法 Download PDF

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TWI889397B
TWI889397B TW113122616A TW113122616A TWI889397B TW I889397 B TWI889397 B TW I889397B TW 113122616 A TW113122616 A TW 113122616A TW 113122616 A TW113122616 A TW 113122616A TW I889397 B TWI889397 B TW I889397B
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mmol
amino
pyrazol
compound
benzamide
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TW113122616A
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TW202440559A (zh
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昭奎 萬
邁克爾勞倫斯 巴斯克斯
李曉東
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大陸商凌科藥業有限公司
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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TW113122616A 2018-12-14 2019-12-13 吡唑基-氨基-嘧啶基衍生物的苯甲醯胺及其組合物和方法 TWI889397B (zh)

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Application Number Priority Date Filing Date Title
PCT/CN2018/121165 WO2020118683A1 (en) 2018-12-14 2018-12-14 Benzamides of pyrazolyl-amino-pyrimidinyl derivatives, and compositions and methods thereof
WOPCT/CN2018/121165 2018-12-14

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TWI889397B true TWI889397B (zh) 2025-07-01

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TW113122616A TWI889397B (zh) 2018-12-14 2019-12-13 吡唑基-氨基-嘧啶基衍生物的苯甲醯胺及其組合物和方法
TW113122615A TWI889396B (zh) 2018-12-14 2019-12-13 吡唑基-氨基-嘧啶基衍生物的苯甲醯胺及其組合物和方法
TW108145807A TWI866940B (zh) 2018-12-14 2019-12-13 吡唑基-氨基-嘧啶基衍生物的苯甲醯胺及其組合物和方法

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TW108145807A TWI866940B (zh) 2018-12-14 2019-12-13 吡唑基-氨基-嘧啶基衍生物的苯甲醯胺及其組合物和方法

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US (6) US12421213B2 (https=)
EP (1) EP3877381A4 (https=)
JP (3) JP7459094B2 (https=)
KR (2) KR20250162926A (https=)
CN (7) CN119118999A (https=)
AU (3) AU2019399939B2 (https=)
BR (1) BR112021011147A2 (https=)
CA (3) CA3122872A1 (https=)
EA (1) EA202191188A1 (https=)
IL (3) IL314086A (https=)
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TW202204333A (zh) 2020-04-08 2022-02-01 美商阿吉歐斯製藥公司 Menin抑制劑及治療癌症之使用方法
CN112661655B (zh) * 2020-12-29 2022-02-18 江苏云朴医药新材料科技有限公司 一种1-氨甲基-1-环丙醇类化合物及其合成方法
EP4577535A1 (en) * 2022-08-22 2025-07-02 Hangzhou Highlightll Pharmaceutical Co., Ltd. Jak1/jak2/tyk2 inhibitors for topical treatment of dermatological diseases
CN115572269B (zh) * 2022-10-08 2024-05-17 广州大学 一种n-三氟异丙基唑类和吲哚化合物及其制备方法
WO2023151724A1 (zh) * 2023-05-19 2023-08-17 凌科药业(杭州)有限公司 一种吡唑基-氨基-嘧啶基衍生物的晶型、制备方法及应用
CN116751191B (zh) * 2023-05-19 2025-09-16 凌科药业(杭州)有限公司 一种吡唑基-氨基-嘧啶基衍生物的晶型、制备方法及应用
WO2024239282A1 (zh) 2023-05-24 2024-11-28 凌科药业(杭州)有限公司 一种药物组合物、外用制剂及其制备方法、应用
CN116983312B (zh) * 2023-05-24 2024-07-05 凌科药业(杭州)有限公司 一种药物组合物、外用制剂及其制备方法、应用
TW202545932A (zh) * 2024-01-26 2025-12-01 大陸商凌科藥業(杭州)有限公司 一種吡唑基-胺基-嘧啶基衍生物的苯甲醯胺的晶型、製備方法及應用
WO2025157231A1 (zh) * 2024-01-26 2025-07-31 凌科药业(杭州)有限公司 一种吡唑基-氨基-嘧啶基衍生物的苯甲酰胺的晶型、制备方法及应用
WO2025256636A1 (zh) * 2024-06-13 2025-12-18 凌科药业(杭州)有限公司 含氮化合物及其制备方法

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