JP2025501056A5 - - Google Patents
Info
- Publication number
- JP2025501056A5 JP2025501056A5 JP2024529408A JP2024529408A JP2025501056A5 JP 2025501056 A5 JP2025501056 A5 JP 2025501056A5 JP 2024529408 A JP2024529408 A JP 2024529408A JP 2024529408 A JP2024529408 A JP 2024529408A JP 2025501056 A5 JP2025501056 A5 JP 2025501056A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- groups
- alkyl
- cyano
- alkyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111655759.X | 2021-12-30 | ||
| CN202111655759 | 2021-12-30 | ||
| CN202210249052 | 2022-03-14 | ||
| CN202210249052.7 | 2022-03-14 | ||
| CN202211064934 | 2022-08-31 | ||
| CN202211064934.2 | 2022-08-31 | ||
| PCT/CN2022/143665 WO2023125877A1 (zh) | 2021-12-30 | 2022-12-29 | 三并环类衍生物抑制剂、其制备方法和应用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025501056A JP2025501056A (ja) | 2025-01-17 |
| JP2025501056A5 true JP2025501056A5 (https=) | 2026-01-07 |
Family
ID=86998069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024529408A Pending JP2025501056A (ja) | 2021-12-30 | 2022-12-29 | 三環系誘導体阻害剤、その製造方法と応用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20250059196A1 (https=) |
| EP (1) | EP4458819A4 (https=) |
| JP (1) | JP2025501056A (https=) |
| KR (1) | KR20240130085A (https=) |
| CN (1) | CN118451068A (https=) |
| AU (1) | AU2022425324A1 (https=) |
| CA (1) | CA3242194A1 (https=) |
| IL (1) | IL313925A (https=) |
| MX (1) | MX2024008008A (https=) |
| TW (1) | TW202333682A (https=) |
| WO (1) | WO2023125877A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202515550A (zh) * | 2023-06-29 | 2025-04-16 | 大陸商上海翰森生物醫藥科技有限公司 | 三并環類抑制劑與抗癌劑在製備抗腫瘤藥物中的聯合應用 |
| CN121285553A (zh) * | 2023-06-29 | 2026-01-06 | 上海翰森生物医药科技有限公司 | 一种三并环类衍生物抑制剂的晶型及其制备方法 |
| CN117534669A (zh) * | 2023-11-01 | 2024-02-09 | 上海凌凯医药科技有限公司 | 五元氮杂环并吡啶醇的制备方法 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6667303B1 (en) | 2001-07-30 | 2003-12-23 | Wyeth | Aryl substituted 1,4-diazepanes and method of use thereof |
| TW200406413A (en) | 2002-06-26 | 2004-05-01 | Glaxo Group Ltd | Compounds |
| GB0510390D0 (en) | 2005-05-20 | 2005-06-29 | Novartis Ag | Organic compounds |
| CN104884448A (zh) | 2012-10-16 | 2015-09-02 | 詹森药业有限公司 | Rorγt的杂芳基连接的喹啉基调节剂 |
| EA201590916A1 (ru) | 2012-11-09 | 2016-02-29 | Корнэлл Юниверсити | Низкомолекулярные ингибиторы malt1 |
| SG11201607895PA (en) | 2014-05-28 | 2016-12-29 | Novartis Ag | Novel pyrazolo pyrimidine derivatives and their use as malt1 inhibitors |
| US9812645B2 (en) | 2015-02-13 | 2017-11-07 | Flexterra, Inc. | Perylene-based semiconductors |
| WO2017057695A1 (ja) | 2015-09-30 | 2017-04-06 | 東レ株式会社 | ジフェニルピラゾール誘導体及びその医薬用途 |
| AU2016352813B2 (en) | 2015-11-13 | 2019-09-19 | Novartis Ag | Novel pyrazolo pyrimidine derivatives |
| US10662156B2 (en) | 2016-07-29 | 2020-05-26 | Toray Industries, Inc. | Guanidine derivative and medical use thereof |
| PE20190656A1 (es) | 2016-07-29 | 2019-05-08 | Lupin Ltd | Compuestos de tiazolo-piridina sustituida como inhibidores de malt1 |
| US10689366B2 (en) | 2016-11-01 | 2020-06-23 | Cornell University | Compounds for MALT1 degredation |
| TWI795381B (zh) | 2016-12-21 | 2023-03-11 | 比利時商健生藥品公司 | 作為ｍａｌｔ１抑制劑之吡唑衍生物 |
| WO2018159650A1 (ja) | 2017-02-28 | 2018-09-07 | 東レ株式会社 | グアニジン誘導体及びその医薬用途 |
| WO2018165385A1 (en) | 2017-03-08 | 2018-09-13 | Cornell University | Inhibitors of malt1 and uses thereof |
| WO2018226150A1 (en) | 2017-06-05 | 2018-12-13 | Medivir Aktiebolag | Pyrazolopyrimidine as malt-1 inhibitors |
| JPWO2019039429A1 (ja) | 2017-08-22 | 2020-07-30 | 日本曹達株式会社 | 環状アミン化合物および有害生物防除剤 |
| AU2019289222B2 (en) * | 2018-06-18 | 2023-07-13 | Janssen Pharmaceutica Nv | Pyrazole derivatives as MALT1 inhibitors |
| EP3810609B1 (en) * | 2018-06-18 | 2024-06-12 | Janssen Pharmaceutica NV | Pyrazole derivatives as malt1 inhibitors |
| KR20210069079A (ko) | 2018-09-28 | 2021-06-10 | 얀센 파마슈티카 엔.브이. | 모노아실글리세롤 리파아제 조절제 |
| TWI848400B (zh) | 2018-11-28 | 2024-07-11 | 日商武田藥品工業股份有限公司 | 雜環化合物及醫藥 |
| CN109665987B (zh) * | 2018-12-28 | 2022-02-18 | 河南大学 | 萘内酰亚胺-多胺缀合物及其制备方法和用途 |
| US20220175760A1 (en) * | 2019-02-22 | 2022-06-09 | Janssen Pharmaceutica Nv | Pharmaceutical formulations |
| EP3953345B1 (en) | 2019-04-11 | 2023-04-05 | Janssen Pharmaceutica NV | Pyridine rings containing derivatives as malt1 inhibitors |
| TW202106684A (zh) | 2019-05-03 | 2021-02-16 | 美商奇奈特生物製藥公司 | Raf激酶抑制劑 |
| CN112125885B (zh) * | 2019-06-25 | 2026-03-17 | 中国药科大学 | 苯并吲哚类双功能分子衍生物及其应用 |
| CN116723839A (zh) | 2020-10-14 | 2023-09-08 | C4医药公司 | 用于降解靶蛋白质的三环杂双官能化合物 |
| CA3194351A1 (en) | 2020-10-14 | 2022-04-21 | Christopher G. Nasveschuk | Tricyclic compounds to degrade neosubstrates for medical therapy |
| WO2022089406A1 (zh) | 2020-10-26 | 2022-05-05 | 上海青煜医药科技有限公司 | 含氮稠杂环类化合物及其制备方法和应用 |
| CN114907358A (zh) * | 2021-02-09 | 2022-08-16 | 上海翰森生物医药科技有限公司 | 含吡啶多环类衍生物调节剂、其制备方法和应用 |
| BR112023017689A2 (pt) * | 2021-03-03 | 2023-11-14 | Janssen Pharmaceutica Nv | Método de tratamento de uma condição com o uso de uma dose terapeuticamente eficaz do inibidor de malt1 jnj-67856633 (1-(1-oxo-1,2-di-hidroisoquinolin-5-il)-5-(trifluorometil)-n(2-(trifluorometil)piridin-4-il)-1h-pirazol-4-carboxamida) |
| TW202317537A (zh) * | 2021-06-18 | 2023-05-01 | 大陸商上海拓界生物醫藥科技有限公司 | 一種malt 1抑制劑及其製備方法和用途 |
-
2022
- 2022-12-29 CN CN202280085536.0A patent/CN118451068A/zh active Pending
- 2022-12-29 CA CA3242194A patent/CA3242194A1/en active Pending
- 2022-12-29 US US18/723,812 patent/US20250059196A1/en active Pending
- 2022-12-29 IL IL313925A patent/IL313925A/en unknown
- 2022-12-29 KR KR1020247020514A patent/KR20240130085A/ko active Pending
- 2022-12-29 AU AU2022425324A patent/AU2022425324A1/en active Pending
- 2022-12-29 WO PCT/CN2022/143665 patent/WO2023125877A1/zh not_active Ceased
- 2022-12-29 JP JP2024529408A patent/JP2025501056A/ja active Pending
- 2022-12-29 EP EP22915126.1A patent/EP4458819A4/en active Pending
- 2022-12-29 MX MX2024008008A patent/MX2024008008A/es unknown
- 2022-12-30 TW TW111150975A patent/TW202333682A/zh unknown
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