|
PT2402319T
(pt)
|
2006-03-31 |
2017-12-11 |
Novartis Ag |
Inibidores de dgat
|
|
WO2008008059A1
(en)
|
2006-07-12 |
2008-01-17 |
Locus Pharmaceuticals, Inc. |
Anti-cancer agents ans uses thereof
|
|
MX2016002544A
(es)
|
2013-09-04 |
2016-06-17 |
Squibb Bristol Myers Co |
Compuestos utiles como inmunomoduladores.
|
|
TR201811077T4
(tr)
|
2013-09-06 |
2018-08-27 |
Aurigene Discovery Tech Ltd |
İmmünomodülatörler olarak 1,3,4-oksadiazol ve 1,3,4-tiyadiyazol türevleri.
|
|
RS57508B1
(sr)
|
2013-09-06 |
2018-10-31 |
Aurigene Discovery Tech Ltd |
1,2,4-derivati oksadiazola kao imunomodulatori
|
|
US9850225B2
(en)
|
2014-04-14 |
2017-12-26 |
Bristol-Myers Squibb Company |
Compounds useful as immunomodulators
|
|
JP6767096B2
(ja)
|
2014-12-11 |
2020-10-14 |
リティックス バイオファーマ エイエス |
免疫チェックポイント阻害剤の組み合わせ
|
|
US10745382B2
(en)
|
2015-10-15 |
2020-08-18 |
Bristol-Myers Squibb Company |
Compounds useful as immunomodulators
|
|
US20170107216A1
(en)
|
2015-10-19 |
2017-04-20 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
MD3377488T2
(ro)
|
2015-11-19 |
2023-02-28 |
Incyte Corp |
Compuși heterociclici ca imunomodulatori
|
|
ES2916874T3
(es)
|
2015-12-17 |
2022-07-06 |
Incyte Corp |
Derivados de N-fenil-piridina-2-carboxamida y su uso como moduladores de la interacción proteína/proteína PD-1/PD-L1
|
|
CA3009474A1
(en)
|
2015-12-22 |
2017-06-29 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
EP3190103A1
(en)
|
2016-01-08 |
2017-07-12 |
Rijksuniversiteit Groningen |
Inhibitors of the pd-1/pd-l1 protein/protein interaction
|
|
ES2906460T3
(es)
|
2016-05-06 |
2022-04-18 |
Incyte Corp |
Compuestos heterocíclicos como inmunomoduladores
|
|
US10882833B2
(en)
|
2016-05-23 |
2021-01-05 |
Institute Of Materia Medica, Chinese Academy Of Medical Sciences |
Phenylate derivative, preparation method therefor, and pharmaceutical composition and uses thereof
|
|
EP3464279B1
(en)
|
2016-05-26 |
2021-11-24 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
SG11201811414TA
(en)
|
2016-06-20 |
2019-01-30 |
Incyte Corp |
Heterocyclic compounds as immunomodulators
|
|
EP3474845B1
(en)
|
2016-06-27 |
2024-03-20 |
ChemoCentryx, Inc. |
Immunomodulator compounds
|
|
BR112018077075A2
(pt)
*
|
2016-06-29 |
2019-04-30 |
Universite De Montreal |
heterociclos de biarilmetila
|
|
AU2017294231B2
(en)
|
2016-07-05 |
2021-09-09 |
Guangzhou Maxinovel Pharmaceuticals Co., Ltd |
Aromatic acetylene or aromatic ethylene compound, intermediate, preparation method, pharmaceutical composition and use thereof
|
|
CN109689640B
(zh)
|
2016-07-08 |
2022-01-04 |
百时美施贵宝公司 |
可用作免疫调节剂的化合物
|
|
MA45669A
(fr)
|
2016-07-14 |
2019-05-22 |
Incyte Corp |
Composés hétérocycliques utilisés comme immunomodulateurs
|
|
US20180057486A1
(en)
|
2016-08-29 |
2018-03-01 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
US10144706B2
(en)
|
2016-09-01 |
2018-12-04 |
Bristol-Myers Squibb Company |
Compounds useful as immunomodulators
|
|
WO2018045142A1
(en)
|
2016-09-02 |
2018-03-08 |
Polaris Pharmaceuticals, Inc. |
Immune checkpoint inhibitors, compositions and methods thereof
|
|
KR102599339B1
(ko)
|
2016-12-20 |
2023-11-08 |
브리스톨-마이어스 스큅 컴퍼니 |
면역조정제로서 유용한 화합물
|
|
WO2018119263A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Heterocyclic compounds derivatives as pd-l1 internalization inducers
|
|
US10308644B2
(en)
|
2016-12-22 |
2019-06-04 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
WO2018119286A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Bicyclic heteroaromatic compounds as immunomodulators
|
|
WO2018119221A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Pyridine derivatives as immunomodulators
|
|
WO2018119236A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Triazolo[1,5-a]pyridine derivatives as immunomodulators
|
|
EP4223369A1
(en)
|
2016-12-22 |
2023-08-09 |
Incyte Corporation |
Immunomodulator compounds and methods of use
|
|
US10654815B2
(en)
|
2016-12-29 |
2020-05-19 |
Shenzhen Chipscreen Biosciences Co., Ltd. |
Urea compound and preparation method and application thereof
|
|
CN108395443B
(zh)
|
2017-02-04 |
2021-05-04 |
广州丹康医药生物有限公司 |
抑制程序性死亡受体配体1的环状化合物及其用途
|
|
JP7150745B2
(ja)
|
2017-03-27 |
2022-10-11 |
ブリストル-マイヤーズ スクイブ カンパニー |
免疫調節剤としての置換イソキノリン誘導体
|
|
BR102018007822A2
(pt)
|
2017-04-20 |
2018-11-06 |
Gilead Sciences, Inc. |
composto, métodos para inibir pd-1, pd-l1 e/ou interação de pd-1/pd-l1 e para tratamento de câncer, composição farmacêutica, e, kit para tratamento de ou prevenção de câncer ou uma doença ou condição
|
|
TW201841896A
(zh)
|
2017-04-26 |
2018-12-01 |
大陸商南京聖和藥業股份有限公司 |
作為pd—l1抑制劑的雜環類化合物
|
|
CN108863963B
(zh)
|
2017-05-08 |
2022-05-27 |
南京圣和药物研发有限公司 |
作为pd-l1抑制剂的杂环类化合物
|
|
CN109400522B
(zh)
|
2017-08-18 |
2023-04-28 |
上海轶诺药业有限公司 |
一种具有pd-l1抑制活性的化合物、其制备方法及用途
|
|
EP3692053A1
(en)
|
2017-10-03 |
2020-08-12 |
Bristol-Myers Squibb Company |
Immunomodulators
|
|
CN109665968B
(zh)
|
2017-10-16 |
2022-02-22 |
四川科伦博泰生物医药股份有限公司 |
并环化合物及其制备方法和用途
|
|
CN109678796B
(zh)
|
2017-10-19 |
2023-01-10 |
上海长森药业有限公司 |
Pd-1/pd-l1小分子抑制剂及其制备方法和用途
|
|
CN109721527B
(zh)
|
2017-10-27 |
2024-03-12 |
广州丹康医药生物有限公司 |
一种新型抗pd-l1化合物、其应用及含其的组合物
|
|
US11629135B2
(en)
|
2017-11-06 |
2023-04-18 |
Jubilant Prodell Llc |
Pyrimidine derivatives as inhibitors of PD1/PD-L1 activation
|
|
WO2019120297A1
(zh)
|
2017-12-22 |
2019-06-27 |
上海海雁医药科技有限公司 |
免疫调节剂及其制法与医药上的用途
|
|
KR102666727B1
(ko)
|
2017-12-29 |
2024-05-21 |
광저우 맥시노벨 파마수티컬스 씨오., 엘티디. |
방향족 비닐 또는 방향족 에틸계 유도체, 그의 제조방법, 중간체, 약물조성물 및 용도
|
|
US11414418B2
(en)
|
2018-01-23 |
2022-08-16 |
Bristol-Myers Squibb Company |
Compounds useful as immunomodulators
|
|
AU2019214089B2
(en)
|
2018-02-05 |
2021-02-11 |
Abbisko Therapeutics Co., Ltd. |
Biaryl derivative, preparation method therefor and pharmaceutical use thereof
|
|
WO2019160882A1
(en)
|
2018-02-13 |
2019-08-22 |
Gilead Sciences, Inc. |
Pd-1/pd-l1 inhibitors
|
|
US11578054B2
(en)
|
2018-03-01 |
2023-02-14 |
Bristol-Myers Squibb Company |
Compounds useful as immunomodulators
|
|
WO2019174533A1
(zh)
|
2018-03-13 |
2019-09-19 |
广东东阳光药业有限公司 |
Pd-1/pd-l1类小分子抑制剂及其在药物中的应用
|
|
CN112105610B
(zh)
|
2018-03-13 |
2024-01-26 |
朱比连特普罗德尔有限责任公司 |
作为pd1/pd-l1相互作用/活化的抑制剂的双环化合物
|
|
SMT202300065T1
(it)
|
2018-03-30 |
2023-05-12 |
Incyte Corp |
Composti eterociclici come immunomodulatori
|
|
US20210040118A1
(en)
|
2018-04-03 |
2021-02-11 |
Betta Pharmaceuticals Co., Ltd |
Immunomodulators, compositions and methods thereof
|
|
KR102591947B1
(ko)
|
2018-04-19 |
2023-10-25 |
길리애드 사이언시즈, 인코포레이티드 |
Pd-1/pd-l1 억제제
|
|
CN112752756B
(zh)
|
2018-05-11 |
2024-06-25 |
因赛特公司 |
作为PD-L1免疫调节剂的四氢-咪唑并[4,5-c]吡啶衍生物
|
|
CN111886219B
(zh)
|
2018-07-11 |
2023-04-25 |
上海和誉生物医药科技有限公司 |
免疫抑制剂及其制备方法和在药学上的应用
|
|
CN112384500B
(zh)
|
2018-07-12 |
2024-05-14 |
贝达药业股份有限公司 |
免疫调节剂及其组合物和制备方法
|
|
PE20210642A1
(es)
|
2018-07-13 |
2021-03-23 |
Gilead Sciences Inc |
Inhibidores de pd-1/pd-l1
|
|
WO2020015716A1
(en)
|
2018-07-19 |
2020-01-23 |
Betta Pharmaceuticals Co., Ltd |
Immunomodulators, compositions and methods thereof
|
|
WO2020015717A1
(en)
|
2018-07-19 |
2020-01-23 |
Betta Pharmaceuticals Co., Ltd |
Immunomodulators, compositions and methods thereof
|
|
EP3831823A4
(en)
|
2018-08-01 |
2022-04-27 |
Shanghai Ennovabio Pharmaceuticals Co., Ltd. |
PREPARATION AND USE OF AN AROMATIC COMPOUND WITH IMMUNEGULATORY FUNCTION
|
|
CN109336857A
(zh)
|
2018-11-13 |
2019-02-15 |
南方医科大学 |
一种含取代联苯的黄酮及其应用
|
|
CN109438263A
(zh)
|
2018-11-28 |
2019-03-08 |
南方医科大学 |
一种含取代联苯的萘及其应用
|
|
CN109503546A
(zh)
|
2019-01-10 |
2019-03-22 |
南方医科大学 |
一种间苯二酚二苯甲醚及其应用
|
|
CN109776377B
(zh)
|
2019-02-01 |
2021-08-24 |
沈阳药科大学 |
吲哚啉类化合物及其制备方法和应用
|
|
CN109776445B
(zh)
|
2019-03-28 |
2022-12-06 |
中国药科大学 |
苯并噁二唑类化合物及其制备方法和医药用途
|
|
BR112021022659A2
(pt)
*
|
2019-05-15 |
2022-03-29 |
Chemocentryx Inc |
Compostos triarílicos para o tratamento de doenças pd-l1
|
|
CN110200959A
(zh)
|
2019-05-30 |
2019-09-06 |
天津科技大学 |
一种黄酮类化合物的应用
|
|
CN110128415B
(zh)
|
2019-05-31 |
2022-03-25 |
沈阳药科大学 |
用作免疫调节剂的吲哚啉类化合物及其制备方法
|
|
KR102841588B1
(ko)
*
|
2019-06-20 |
2025-08-01 |
케모센트릭스, 인크. |
Pd-l1 질환의 치료를 위한 화합물
|