JP2025163128A5 - - Google Patents

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Publication number
JP2025163128A5
JP2025163128A5 JP2025128256A JP2025128256A JP2025163128A5 JP 2025163128 A5 JP2025163128 A5 JP 2025163128A5 JP 2025128256 A JP2025128256 A JP 2025128256A JP 2025128256 A JP2025128256 A JP 2025128256A JP 2025163128 A5 JP2025163128 A5 JP 2025163128A5
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JP
Japan
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substituted
unsubstituted
straight
reducing
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JP2025128256A
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English (en)
Japanese (ja)
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JP2025163128A (ja
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Priority claimed from PCT/IL2020/050524 external-priority patent/WO2020230134A1/en
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Publication of JP2025163128A publication Critical patent/JP2025163128A/ja
Publication of JP2025163128A5 publication Critical patent/JP2025163128A5/ja
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JP2025128256A 2019-05-14 2025-07-31 イミダゾール３－オキシド誘導体系ａｃｓｓ２阻害剤及びその使用方法 Pending JP2025163128A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962847348P 2019-05-14 2019-05-14
PCT/IL2020/050524 WO2020230134A1 (en) 2019-05-14 2020-05-14 Acss2 inhibitors and methods of use thereof
ILPCT/IL2020/050524 2020-05-14
PCT/IL2021/050541 WO2021229571A1 (en) 2019-05-14 2021-05-12 Imidazole 3-oxide derivative based acss2 inhibitors and methods of use thereof
JP2022568774A JP7723011B2 (ja) 2019-05-14 2021-05-12 イミダゾール３－オキシド誘導体系ａｃｓｓ２阻害剤及びその使用方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2022568774A Division JP7723011B2 (ja) 2019-05-14 2021-05-12 イミダゾール３－オキシド誘導体系ａｃｓｓ２阻害剤及びその使用方法

Publications (2)

Publication Number Publication Date
JP2025163128A JP2025163128A (ja) 2025-10-28
JP2025163128A5 true JP2025163128A5 (https=) 2025-11-06

Family

ID=73288933

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2021567836A Pending JP2022532718A (ja) 2019-05-14 2020-05-14 Ａｃｓｓ２阻害剤およびその使用方法
JP2021567839A Pending JP2022532719A (ja) 2019-05-14 2020-05-14 Ａｃｓｓ２阻害剤およびその使用方法
JP2022568774A Active JP7723011B2 (ja) 2019-05-14 2021-05-12 イミダゾール３－オキシド誘導体系ａｃｓｓ２阻害剤及びその使用方法
JP2025128256A Pending JP2025163128A (ja) 2019-05-14 2025-07-31 イミダゾール３－オキシド誘導体系ａｃｓｓ２阻害剤及びその使用方法

Family Applications Before (3)

Application Number Title Priority Date Filing Date
JP2021567836A Pending JP2022532718A (ja) 2019-05-14 2020-05-14 Ａｃｓｓ２阻害剤およびその使用方法
JP2021567839A Pending JP2022532719A (ja) 2019-05-14 2020-05-14 Ａｃｓｓ２阻害剤およびその使用方法
JP2022568774A Active JP7723011B2 (ja) 2019-05-14 2021-05-12 イミダゾール３－オキシド誘導体系ａｃｓｓ２阻害剤及びその使用方法

Country Status (12)

Country Link
US (3) US12441689B2 (https=)
EP (3) EP3969439A4 (https=)
JP (4) JP2022532718A (https=)
KR (3) KR20220024014A (https=)
CN (3) CN114127049A (https=)
AU (3) AU2020273727A1 (https=)
BR (2) BR112021022977A2 (https=)
CA (3) CA3136083A1 (https=)
IL (3) IL297883A (https=)
MX (3) MX2021013786A (https=)
SG (2) SG11202112277PA (https=)
WO (3) WO2020230136A1 (https=)

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US12133852B2 (en) 2017-11-15 2024-11-05 Epivario, Inc. ACSS2 inhibitors and methods of use thereof
US11795160B2 (en) 2019-02-22 2023-10-24 Insilico Medicine Ip Limited Kinase inhibitors
JP2022532718A (ja) * 2019-05-14 2022-07-19 メタボメッド リミテッド Ａｃｓｓ２阻害剤およびその使用方法
BR112022010924A2 (pt) 2019-12-06 2022-09-06 Vertex Pharma Tetra-hidrofuranos substituídos como moduladores de canais de sódio
CN112480085B (zh) * 2020-12-17 2022-10-25 上海英诺富成生物科技有限公司 一种化合物或其药学上可接受的盐、异构体、前药、多晶型物或溶剂化物
CA3208490A1 (en) 2021-02-24 2022-09-01 Aleksandrs Zavoronkovs Analogs for the treatment of disease
SMT202500481T1 (it) 2021-06-04 2026-01-12 Vertex Pharma N-(idrossialchil(etero)aril)tetraidrofuran carbossammidi come modulatori di canali del sodio
CN114044754A (zh) * 2021-11-23 2022-02-15 贵州大学 一类5-三氟甲基-4-吡唑衍生物的制备方法及其在抑制肿瘤细胞上的应用
CN114716380B (zh) * 2022-04-01 2024-06-21 新乡医学院 一种相转移催化的4-取代吡唑酮类化合物不对称氟化方法
CN116808042A (zh) * 2023-08-08 2023-09-29 江苏省人民医院（南京医科大学第一附属医院） 乙酰辅酶a合成酶2抑制剂在治疗胰腺神经内分泌肿瘤中的应用
CN118344267A (zh) * 2024-04-17 2024-07-16 广东广康生化科技股份有限公司 一种联苯肼酯高效合成新方法

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DE2324893A1 (de) 1973-05-17 1974-12-12 Hoechst Ag 1-hydroxy-imidazole und verfahren zu ihrer herstellung
US3905997A (en) 1974-06-21 1975-09-16 Warner Lambert Co 3-Aryl-5-oxo-2-pyrazoline-4-carboxanilides and process therefor
US4207317A (en) * 1978-03-13 1980-06-10 Ciba-Geigy Corporation 1-Aryl-4-carbamoyl-pyrazolin-5-ones
DD140966A1 (de) * 1978-12-28 1980-04-09 Doerthe Creuzburg Mittel zur regulierung des pflanzenwachstums
JPH11291635A (ja) * 1998-04-06 1999-10-26 Mitsubishi Paper Mills Ltd 感熱記録材料
ATE299499T1 (de) * 1998-11-09 2005-07-15 Black James Foundation Gastrin und cholecystokinin rezeptor ligande
AR034897A1 (es) 2001-08-07 2004-03-24 Hoffmann La Roche Derivados n-monoacilados de o-fenilendiaminas, sus analogos heterociclicos de seis miembros y su uso como agentes farmaceuticos
CN101851173A (zh) * 2001-09-14 2010-10-06 梅特希尔基因公司 组蛋白脱乙酰化酶抑制剂
DE602005009021D1 (de) * 2004-12-17 2008-09-25 Lilly Co Eli Neue mch-rezeptorantagonisten
WO2007026215A1 (en) * 2005-08-29 2007-03-08 Glenmark Pharmaceuticals S.A. Pyrazole derivatives as cannabinoid receptor ligands, pharmaceutical compositions containing? them, and processes for their preparation
US9334244B2 (en) * 2010-05-12 2016-05-10 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of ATR kinase
US9073911B2 (en) * 2011-06-09 2015-07-07 Hoffmann-La Roche Inc. Pyrazole derivatives
EP2794592A1 (en) * 2011-12-23 2014-10-29 Novartis AG Compounds for inhibiting the interaction of bcl2 with binding partners
WO2013159224A1 (en) 2012-04-25 2013-10-31 University Of Manitoba 2-carbamo(thio)yl-1,3- dioxopropyl derivatives in cancer therapy
WO2015175845A1 (en) * 2014-05-15 2015-11-19 Peloton Therapeutics, Inc. Benzimidazole derivatives and uses thereof
US20170190689A1 (en) 2016-01-05 2017-07-06 Incyte Corporation Pyridine and pyridimine compounds as pi3k-gamma inhibitors
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IL274504B2 (en) * 2017-11-15 2024-12-01 Epivario Inc Acss2 inhibitors and methods of use thereof
JP2022532718A (ja) * 2019-05-14 2022-07-19 メタボメッド リミテッド Ａｃｓｓ２阻害剤およびその使用方法

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