CN114127049A - Acss2抑制剂和其使用方法 - Google Patents
Acss2抑制剂和其使用方法 Download PDFInfo
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- CN114127049A CN114127049A CN202080050593.6A CN202080050593A CN114127049A CN 114127049 A CN114127049 A CN 114127049A CN 202080050593 A CN202080050593 A CN 202080050593A CN 114127049 A CN114127049 A CN 114127049A
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| US12133852B2 (en) | 2017-11-15 | 2024-11-05 | Epivario, Inc. | ACSS2 inhibitors and methods of use thereof |
| US11739078B2 (en) | 2019-02-22 | 2023-08-29 | Insilico Medicine Ip Limited | Methods of inhibiting kinases |
| CA3164134A1 (en) | 2019-12-06 | 2021-06-10 | Vertex Pharmaceuticals Incorporated | Substituted tetrahydrofurans as modulators of sodium channels |
| CN112480085B (zh) * | 2020-12-17 | 2022-10-25 | 上海英诺富成生物科技有限公司 | 一种化合物或其药学上可接受的盐、异构体、前药、多晶型物或溶剂化物 |
| CA3208490A1 (en) | 2021-02-24 | 2022-09-01 | Aleksandrs Zavoronkovs | Analogs for the treatment of disease |
| SI4347031T1 (sl) | 2021-06-04 | 2026-01-30 | Vertex Pharmaceuticals Incorporated | N-(hidroksialkil (hetero)aril) tetrahidrofuran karboksamidi kot modulatorji natrijevih kanalčkov |
| CN114044754A (zh) * | 2021-11-23 | 2022-02-15 | 贵州大学 | 一类5-三氟甲基-4-吡唑衍生物的制备方法及其在抑制肿瘤细胞上的应用 |
| CN114716380B (zh) * | 2022-04-01 | 2024-06-21 | 新乡医学院 | 一种相转移催化的4-取代吡唑酮类化合物不对称氟化方法 |
| CN116808042A (zh) * | 2023-08-08 | 2023-09-29 | 江苏省人民医院(南京医科大学第一附属医院) | 乙酰辅酶a合成酶2抑制剂在治疗胰腺神经内分泌肿瘤中的应用 |
| CN118344267A (zh) * | 2024-04-17 | 2024-07-16 | 广东广康生化科技股份有限公司 | 一种联苯肼酯高效合成新方法 |
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| EP3687628A4 (en) * | 2017-09-26 | 2021-09-22 | The Trustees of The University of Pennsylvania | COMPOSITIONS AND METHODS TO INHIBIT ACSS2 |
| KR20200089291A (ko) * | 2017-11-15 | 2020-07-24 | 메타보메드 리미티드 | Acss2 저해제 및 이의 사용 방법 |
| US12441689B2 (en) * | 2019-05-14 | 2025-10-14 | Epivario, Inc. | ACSS2 inhibitors and methods of use thereof |
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| CN115697974A (zh) * | 2019-05-14 | 2023-02-03 | 美特波米德有限公司 | 基于咪唑3-氧化物衍生物的acss2抑制剂和其使用方法 |
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