JP2025027013A5 - - Google Patents

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Publication number
JP2025027013A5
JP2025027013A5 JP2024205131A JP2024205131A JP2025027013A5 JP 2025027013 A5 JP2025027013 A5 JP 2025027013A5 JP 2024205131 A JP2024205131 A JP 2024205131A JP 2024205131 A JP2024205131 A JP 2024205131A JP 2025027013 A5 JP2025027013 A5 JP 2025027013A5
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JP2024205131A
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JP2025027013A (ja
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JP2024205131A 2014-09-28 2024-11-26 刺激性骨髄系細胞及び非刺激性骨髄系細胞の調節 Pending JP2025027013A (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201462056569P 2014-09-28 2014-09-28
US62/056,569 2014-09-28
US201562129883P 2015-03-08 2015-03-08
US62/129,883 2015-03-08
JP2020207244A JP7168641B2 (ja) 2014-09-28 2020-12-15 刺激性骨髄系細胞及び非刺激性骨髄系細胞の調節
JP2022172033A JP7668257B2 (ja) 2014-09-28 2022-10-27 刺激性骨髄系細胞及び非刺激性骨髄系細胞の調節

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JP2025027013A JP2025027013A (ja) 2025-02-26
JP2025027013A5 true JP2025027013A5 (enExample) 2025-09-30

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JP2017516664A Active JP6811711B2 (ja) 2014-09-28 2015-09-28 刺激性骨髄系細胞及び非刺激性骨髄系細胞の調節
JP2020207244A Active JP7168641B2 (ja) 2014-09-28 2020-12-15 刺激性骨髄系細胞及び非刺激性骨髄系細胞の調節
JP2022172033A Active JP7668257B2 (ja) 2014-09-28 2022-10-27 刺激性骨髄系細胞及び非刺激性骨髄系細胞の調節
JP2024205131A Pending JP2025027013A (ja) 2014-09-28 2024-11-26 刺激性骨髄系細胞及び非刺激性骨髄系細胞の調節

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JP2017516664A Active JP6811711B2 (ja) 2014-09-28 2015-09-28 刺激性骨髄系細胞及び非刺激性骨髄系細胞の調節
JP2020207244A Active JP7168641B2 (ja) 2014-09-28 2020-12-15 刺激性骨髄系細胞及び非刺激性骨髄系細胞の調節
JP2022172033A Active JP7668257B2 (ja) 2014-09-28 2022-10-27 刺激性骨髄系細胞及び非刺激性骨髄系細胞の調節

Country Status (12)

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US (3) US10428143B2 (enExample)
EP (1) EP3197495A4 (enExample)
JP (4) JP6811711B2 (enExample)
KR (3) KR102506663B1 (enExample)
CN (1) CN106999585A (enExample)
AU (3) AU2015319809B2 (enExample)
CA (1) CA2961950A1 (enExample)
EA (1) EA034921B1 (enExample)
IL (4) IL283834B (enExample)
MX (2) MX388410B (enExample)
WO (1) WO2016049641A1 (enExample)
ZA (1) ZA201701658B (enExample)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3081576T3 (pl) 2013-12-12 2020-03-31 Shanghai Hengrui Pharmaceutical Co., Ltd. Przeciwciało anty pd-1, jego fragment wiążący antygen i ich zastosowanie medyczne
US20170240631A1 (en) 2014-08-08 2017-08-24 Alector Llc Anti-trem2 antibodies and methods of use thereof
CA2961950A1 (en) * 2014-09-28 2016-03-31 The Regents Of The University Of California Modulation of stimulatory and non-stimulatory myeloid cells
US20170151281A1 (en) 2015-02-19 2017-06-01 Batu Biologics, Inc. Chimeric antigen receptor dendritic cell (car-dc) for treatment of cancer
CN109906381B (zh) * 2016-08-31 2023-03-31 新加坡科技研究局 鉴别、靶向以及分离人树突细胞(dc)前体“前dc”的方法及其用途
EP3516396B1 (en) 2016-09-26 2024-11-13 F. Hoffmann-La Roche AG Predicting response to pd-1 axis inhibitors
EP4039260B1 (en) 2017-02-07 2024-04-17 Saitama Medical University Cd62llow cd4+ t-cells for treating or preventing cancer
JOP20190248A1 (ar) 2017-04-21 2019-10-20 Amgen Inc بروتينات ربط مولد ضد trem2 واستخداماته
CN107267555B (zh) * 2017-05-27 2020-03-20 上海优卡迪生物医药科技有限公司 一种基于octs技术的恶性胶质瘤car-t治疗载体及其构建方法和应用
DK3601358T5 (da) * 2017-08-03 2024-09-02 Alector Llc Anti-trem2-antistoffer og fremgangsmåder til anvendelse deraf
WO2019032624A1 (en) * 2017-08-08 2019-02-14 Pionyr Immunotherapeutics, Inc. COMPOSITIONS AND METHODS FOR DEACTIVATING TREM1-EXPRESSING MESHLOID CELLS
CA3079999A1 (en) * 2017-11-07 2019-05-16 The Board Of Regents Of The University Of Texas System Targeting lilrb4 with car-t or car-nk cells in the treatment of cancer
CN111712518B (zh) 2017-11-17 2025-03-25 默沙东有限责任公司 对免疫球蛋白样转录物3(ilt3)具有特异性的抗体及其用途
KR102860409B1 (ko) * 2017-12-12 2025-09-16 파이오니어 임뮤노테라퓨틱스, 인코퍼레이티드 항-trem2 항체 및 관련 방법
CN108085393B (zh) * 2018-01-31 2020-06-02 青岛泱深生物医药有限公司 肾透明细胞癌相关生物标志物及其应用
SG11202007018QA (en) * 2018-02-02 2020-08-28 Oncoimmune Inc Methods of selecting and designing safer and more effective anti-ctla-4 antibodies for cancer therapy
US20210261657A1 (en) * 2018-06-21 2021-08-26 Faron Pharmaceuticals Oy Treatment of cancer with clever-1 inhibition in combination with pd-1/pd-l1 inhibitor
US12202855B2 (en) 2018-06-25 2025-01-21 Peter Maccallum Cancer Institute Modified T cells and uses thereof
UY38407A (es) * 2018-10-15 2020-05-29 Novartis Ag Anticuerpos estabilizadores de trem2
EP3876977A1 (en) 2018-11-06 2021-09-15 The Regents Of The University Of California Chimeric antigen receptors for phagocytosis
CA3120875A1 (en) * 2018-12-11 2020-06-18 Pionyr Immunotherapeutics, Inc. Methods of using anti-trem2 antibodies
CN109609463B (zh) * 2019-01-10 2022-07-01 中国医学科学院肿瘤医院 一种宫颈癌肿瘤原代细胞分离及培养方法
US10836828B2 (en) 2019-02-06 2020-11-17 Pionyr Immunotherapeutics, Inc. Anti-TREM1 antibodies and related methods
EP3927743A1 (en) 2019-02-20 2021-12-29 Denali Therapeutics Inc. Anti-trem2 antibodies and methods of use thereof
TW202035702A (zh) 2019-02-20 2020-10-01 學校法人埼玉醫科大學 評價藉由放射線治療之抗腫瘤免疫效果之末梢血液生物標記
TW202035701A (zh) * 2019-02-20 2020-10-01 學校法人埼玉醫科大學 用以預測於癌症免疫療法下之長期存活之方法及組合物
US11013764B2 (en) 2019-04-30 2021-05-25 Myeloid Therapeutics, Inc. Engineered phagocytic receptor compositions and methods of use thereof
WO2020247290A1 (en) * 2019-06-04 2020-12-10 Academia Sinica Ligands targed to epidermal growth factor receptors and compositions for use in treating tumors
CA3147182A1 (en) * 2019-08-13 2021-02-18 Tohoku University Novel immune checkpoint inhibitors and uses thereof
EP4025686A4 (en) 2019-09-03 2023-09-13 Myeloid Therapeutics, Inc. Methods and compositions for genomic integration
CN110836974B (zh) * 2019-11-07 2022-09-09 西安交通大学医学院第一附属医院 Flt3lg蛋白在制备肺腺癌术后预后评估试剂或者试剂盒中的应用
US10980836B1 (en) 2019-12-11 2021-04-20 Myeloid Therapeutics, Inc. Therapeutic cell compositions and methods of manufacturing and use thereof
JP2023507110A (ja) 2019-12-19 2023-02-21 エヌジーエム バイオファーマシューティカルス,インコーポレーテッド Ilt3結合剤及びその使用方法
KR20220131246A (ko) 2020-01-13 2022-09-27 데날리 테라퓨틱스 인크. 항-trem2 항체 및 이의 사용 방법
IL272390A (en) 2020-01-30 2021-08-31 Yeda Res & Dev Cancer treatment methods
WO2021209495A1 (en) * 2020-04-14 2021-10-21 Symphogen A/S Anti-flt3 antibodies and compositions
WO2022057910A1 (en) * 2020-09-17 2022-03-24 I-Mab Biopharma Co., Ltd Combination therapies targeting c5ar and pd-1/pd-l1 pathways
CA3197423A1 (en) 2020-11-04 2022-05-12 Daniel Getts Engineered chimeric fusion protein compositions and methods of use thereof
US11617767B2 (en) 2020-11-20 2023-04-04 Simcere Innovation, Inc. Armed dual CAR-T compositions and methods for cancer immunotherapy
GB2620502A (en) * 2021-03-09 2024-01-10 Mascarenhas Desmond Modulation of mammalian cell lineage by synthetic immodulins
AU2022237618A1 (en) 2021-03-17 2023-10-12 Myeloid Therapeutics, Inc. Engineered chimeric fusion protein compositions and methods of use thereof
JP2024518100A (ja) 2021-05-11 2024-04-24 マイエロイド・セラピューティクス,インコーポレーテッド ゲノム組込みのための方法および組成物
JP2024534976A (ja) * 2021-09-08 2024-09-26 ジョイント・ストック・カンパニー “バイオキャド” Mhcタンパク質に基づくヘテロ二量体を含む二重特異性抗体
WO2023076983A1 (en) 2021-10-28 2023-05-04 Gilead Sciences, Inc. Pyridizin-3(2h)-one derivatives
JP7787991B2 (ja) 2021-10-29 2025-12-17 ギリアード サイエンシーズ, インコーポレイテッド Cd73化合物
WO2023094436A1 (en) * 2021-11-26 2023-06-01 Technische Universität Dresden Placental macrophages for cell therapy
AU2022419982A1 (en) 2021-12-22 2024-06-06 Gilead Sciences, Inc. Ikaros zinc finger family degraders and uses thereof
WO2023122615A1 (en) 2021-12-22 2023-06-29 Gilead Sciences, Inc. Ikaros zinc finger family degraders and uses thereof
TW202340168A (zh) 2022-01-28 2023-10-16 美商基利科學股份有限公司 Parp7抑制劑
TW202346277A (zh) 2022-03-17 2023-12-01 美商基利科學股份有限公司 Ikaros鋅指家族降解劑及其用途
PE20250157A1 (es) 2022-04-21 2025-01-22 Gilead Sciences Inc Compuestos de modulacion de kras g12d
CN119384415A (zh) 2022-07-01 2025-01-28 吉利德科学公司 Cd73化合物
US20240254118A1 (en) 2022-12-22 2024-08-01 Gilead Sciences, Inc. Prmt5 inhibitors and uses thereof
KR20250167002A (ko) 2023-04-11 2025-11-28 길리애드 사이언시즈, 인코포레이티드 Kras 조절 화합물
CN121079300A (zh) 2023-04-21 2025-12-05 吉利德科学公司 Prmt5抑制剂及其用途
US20250042922A1 (en) 2023-06-30 2025-02-06 Gilead Sciences, Inc. Kras modulating compounds
WO2025024811A1 (en) 2023-07-26 2025-01-30 Gilead Sciences, Inc. Parp7 inhibitors
US20250066328A1 (en) 2023-07-26 2025-02-27 Gilead Sciences, Inc. Parp7 inhibitors
TW202515919A (zh) 2023-09-01 2025-04-16 比利時商艾托斯比利時公司 抗trem2抗體及使用方法
US20250101042A1 (en) 2023-09-08 2025-03-27 Gilead Sciences, Inc. Kras g12d modulating compounds
WO2025054530A1 (en) 2023-09-08 2025-03-13 Gilead Sciences, Inc. Pyrimidine-containing polycyclic derivatives as kras g12d modulating compounds
WO2025096589A1 (en) 2023-11-03 2025-05-08 Gilead Sciences, Inc. Prmt5 inhibitors and uses thereof
WO2025137640A1 (en) 2023-12-22 2025-06-26 Gilead Sciences, Inc. Azaspiro wrn inhibitors
WO2025245003A1 (en) 2024-05-21 2025-11-27 Gilead Sciences, Inc. Prmt5 inhibitors and uses thereof

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
US5208020A (en) 1989-10-25 1993-05-04 Immunogen Inc. Cytotoxic agents comprising maytansinoids and their therapeutic use
GB9014932D0 (en) 1990-07-05 1990-08-22 Celltech Ltd Recombinant dna product and method
US5571894A (en) 1991-02-05 1996-11-05 Ciba-Geigy Corporation Recombinant antibodies specific for a growth factor receptor
WO1994004679A1 (en) 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
EP0940468A1 (en) 1991-06-14 1999-09-08 Genentech, Inc. Humanized antibody variable domain
FI941572A7 (fi) 1991-10-07 1994-05-27 Oncologix Inc Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenete lmä
JPH05244982A (ja) 1991-12-06 1993-09-24 Sumitomo Chem Co Ltd 擬人化b−b10
DE69334255D1 (de) 1992-02-06 2009-02-12 Novartis Vaccines & Diagnostic Marker für Krebs und biosynthetisches Bindeprotein dafür
US7294331B2 (en) * 1994-03-07 2007-11-13 Immunex Corporation Methods of using flt3-ligand in hematopoietic cell transplantation
DE19638745C2 (de) * 1996-09-11 2001-05-10 Schering Ag Monoklonale Antikörper gegen die extrazelluläre Domäne des menschlichen VEGF - Rezeptorproteins (KDR)
FR2807767B1 (fr) 2000-04-12 2005-01-14 Lab Francais Du Fractionnement Anticorps monoclonaux anti-d
US7442777B2 (en) * 2000-11-29 2008-10-28 Arius Research Inc. Cytotoxicity mediation of cells evidencing surface expression of CD63
US8231878B2 (en) * 2001-03-20 2012-07-31 Cosmo Research & Development S.P.A. Receptor trem (triggering receptor expressed on myeloid cells) and uses thereof
US8981061B2 (en) 2001-03-20 2015-03-17 Novo Nordisk A/S Receptor TREM (triggering receptor expressed on myeloid cells) and uses thereof
US8088387B2 (en) 2003-10-10 2012-01-03 Immunogen Inc. Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
US8399618B2 (en) 2004-10-21 2013-03-19 Xencor, Inc. Immunoglobulin insertions, deletions, and substitutions
US20070213660A1 (en) 2004-10-29 2007-09-13 Mark Richards Fibrin sealant delivery device including pressure monitoring, and method and kits thereof
AU2006230413B8 (en) 2005-03-31 2011-01-20 Xencor, Inc Fc variants with optimized properties
WO2006138005A2 (en) 2005-05-10 2006-12-28 Monsanto Technology, Llc Genes and uses for plant improvement
ES2547463T3 (es) 2005-06-17 2015-10-06 Merck Sharp & Dohme Corp. Moléculas de unión a ILT3 y usos de las mismas
US20090202544A1 (en) * 2006-02-02 2009-08-13 The Trustees Of Columbia University In The City Of New York Methods of Treating Diseases by Targeting Silt3
WO2008094176A2 (en) 2006-06-19 2008-08-07 Tolerx, Inc. Ilt3 binding molecules and uses therefor
EP2535354B1 (en) * 2007-06-18 2017-01-11 Merck Sharp & Dohme B.V. Antibodies to human programmed death receptor pd-1
WO2011116299A2 (en) 2010-03-18 2011-09-22 Colorado State University Research Foundation Myeloid derived suppressor cell inhibiting agents
RS58810B1 (sr) 2009-06-03 2019-07-31 Immunogen Inc Metodi konjugacije
SI2506871T1 (sl) 2009-11-30 2016-12-30 Janssen Biotech, Inc. Mutanti Fc protitelesa z odstranjenimi efektorskimi funkcijami
AU2010339359A1 (en) 2009-12-29 2012-07-26 Kyowa Hakko Kirin Co., Ltd. Anti-CD27 antibody
US20110262348A1 (en) 2010-03-29 2011-10-27 Vrije Universiteit Brussel Selective targeting of intratumoral cells
JP2013523098A (ja) 2010-03-29 2013-06-17 ザイムワークス,インコーポレイテッド 強化又は抑制されたエフェクター機能を有する抗体
WO2012031008A2 (en) * 2010-08-31 2012-03-08 The General Hospital Corporation Cancer-related biological materials in microvesicles
US8427899B2 (en) * 2010-10-29 2013-04-23 Taiwan Semiconductor Manufacturing Company, Ltd. Self-adaptive sensing design
HUE041335T2 (hu) 2011-03-29 2019-05-28 Roche Glycart Ag Antitest FC-variánsok
CN109517897A (zh) * 2011-04-28 2019-03-26 南加利福尼亚大学 人类髓源抑制性细胞癌症标记
US9696312B2 (en) 2011-09-02 2017-07-04 The Trustees Of Columbia University In The City Of New York Diagnosis and treatment of cancer expressing ILT3 or ILT3 ligand
CA2877081C (en) 2011-09-27 2020-09-22 The Governing Council Of The University Of Toronto Molecular display method
EP2855526B1 (en) * 2012-05-24 2018-11-07 VIB vzw Anti-macrophage mannose receptor immunoglobulin single variable domains for targeting and in vivo imaging of tumor-associated macrophages
WO2014025828A1 (en) 2012-08-06 2014-02-13 The Regents Of The University Of California Engineered antibody fragments for targeting and imaging cd8 expression in vivo
TWI589590B (zh) 2012-11-07 2017-07-01 輝瑞股份有限公司 抗切口3(anti-notch3)抗體及抗體-藥物共軛體
WO2014074942A1 (en) 2012-11-08 2014-05-15 Illumina, Inc. Risk variants of alzheimer's disease
CA2894879A1 (en) * 2012-12-19 2014-06-26 Amplimmune, Inc. B7-h4 specific antibodies, and compositions and methods of use thereof
US9617266B2 (en) * 2013-03-05 2017-04-11 Merck Patent Gmbh Imidazopyrimidine derivatives
GB201311487D0 (en) 2013-06-27 2013-08-14 Alligator Bioscience Ab Bispecific molecules
WO2015035365A1 (en) * 2013-09-09 2015-03-12 The Nohns Hopkins University Targeting the m2-tumor associated macrophage for cancer therapy
RU2016129959A (ru) * 2013-12-30 2018-02-02 Эпимаб Биотерепьютикс Инк. Иммуноглобулин с тандемным расположением fab-фрагментов и его применение
US20170240631A1 (en) * 2014-08-08 2017-08-24 Alector Llc Anti-trem2 antibodies and methods of use thereof
CA2961950A1 (en) 2014-09-28 2016-03-31 The Regents Of The University Of California Modulation of stimulatory and non-stimulatory myeloid cells
WO2016064895A1 (en) 2014-10-20 2016-04-28 The Brigham And Women's Hospital, Inc. Targeting apolipoprotein e (apoe) in neurologic disease
EP3237450B1 (en) * 2014-12-22 2021-03-03 The Rockefeller University Anti-mertk agonistic antibodies and uses thereof
WO2017058866A1 (en) 2015-09-28 2017-04-06 Precision Immune, Inc. Anti-trem2 antibodies and uses thereof
US20190330335A1 (en) 2015-10-06 2019-10-31 Alector Llc Anti-trem2 antibodies and methods of use thereof
AU2017300040A1 (en) 2016-07-22 2019-01-24 Deutsches Zentrum Für Neurodegenerative Erkrankungen E.V. (Dzne) TREM2 cleavage modulators and uses thereof
US10167796B2 (en) 2017-05-17 2019-01-01 GM Global Technology Operations LLC Gasoline particulate filter regeneration strategy
JP2020530986A (ja) 2017-07-27 2020-11-05 ノバルティス アーゲー シェダーゼ耐性trem2変異体
DK3601358T5 (da) 2017-08-03 2024-09-02 Alector Llc Anti-trem2-antistoffer og fremgangsmåder til anvendelse deraf
WO2019055841A1 (en) 2017-09-14 2019-03-21 Denali Therapeutics Inc. ANTI-TREM2 ANTIBODIES AND METHODS OF USE
KR102860409B1 (ko) 2017-12-12 2025-09-16 파이오니어 임뮤노테라퓨틱스, 인코퍼레이티드 항-trem2 항체 및 관련 방법
CA3120875A1 (en) 2018-12-11 2020-06-18 Pionyr Immunotherapeutics, Inc. Methods of using anti-trem2 antibodies

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