JP2024523363A5 - - Google Patents

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Publication number
JP2024523363A5
JP2024523363A5 JP2023577658A JP2023577658A JP2024523363A5 JP 2024523363 A5 JP2024523363 A5 JP 2024523363A5 JP 2023577658 A JP2023577658 A JP 2023577658A JP 2023577658 A JP2023577658 A JP 2023577658A JP 2024523363 A5 JP2024523363 A5 JP 2024523363A5
Authority
JP
Japan
Prior art keywords
modified oligonucleotide
nucleoside
modified
nucleic acid
nucleosides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023577658A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024523363A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/033936 external-priority patent/WO2022266415A1/en
Publication of JP2024523363A publication Critical patent/JP2024523363A/ja
Publication of JP2024523363A5 publication Critical patent/JP2024523363A5/ja
Pending legal-status Critical Current

Links

JP2023577658A 2021-06-18 2022-06-17 Ｉｆｎａｒ１の発現を低減するための化合物及び方法 Pending JP2024523363A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163212476P 2021-06-18 2021-06-18
US63/212,476 2021-06-18
PCT/US2022/033936 WO2022266415A1 (en) 2021-06-18 2022-06-17 Compounds and methods for reducing ifnar1 expression

Publications (2)

Publication Number Publication Date
JP2024523363A JP2024523363A (ja) 2024-06-28
JP2024523363A5 true JP2024523363A5 (https=) 2025-06-25

Family

ID=84527458

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023577658A Pending JP2024523363A (ja) 2021-06-18 2022-06-17 Ｉｆｎａｒ１の発現を低減するための化合物及び方法

Country Status (4)

Country Link
US (1) US20250188476A1 (https=)
EP (1) EP4355338A4 (https=)
JP (1) JP2024523363A (https=)
WO (1) WO2022266415A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2022293556A1 (en) 2021-06-18 2024-01-18 Ionis Pharmaceuticals, Inc. Compounds and methods for reducing ifnar1 expression
CN121219414A (zh) * 2023-04-21 2025-12-26 瑟卡尔纳制药有限公司 Nrp1-特异性反义寡核苷酸及其在预防和/或治疗疾病中的用途
WO2024253741A1 (en) * 2023-06-07 2024-12-12 Massachusetts Institute Of Technology Rna-loaded lipid nanoparticles

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2211877A1 (en) * 1995-01-30 1996-08-08 Hybridon, Inc. Human immunodeficiency virus transcription inhibitors and methods of their use
WO2012068630A1 (en) * 2010-11-26 2012-05-31 The University Of Melbourne Methods and compositions comprising antagonists of type 1 interferon-mediated signalling for reducing a neuroinflammatory response in the central nervous system following a stroke
JP2016521556A (ja) * 2013-06-07 2016-07-25 ラナ セラピューティクス インコーポレイテッド Ｆｏｘｐ３発現を調節するための組成物及び方法
US20200345756A1 (en) * 2017-10-10 2020-11-05 University Of Virginia Patent Foundation Compositions and methods for treating age-related macular degeneration and geographic atrophy
JP7013632B2 (ja) * 2018-09-18 2022-02-01 アイ－エムエービー バイオファーマ （ハンジョウ） カンパニー リミテッド 自己免疫疾患を治療するための抗ｉｆｎａｒ１抗体
US20220064636A1 (en) * 2018-10-05 2022-03-03 Ionis Pharmaceuticals, Inc. Modified oligomeric compounds and uses thereof

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