JP2024520205A5 - - Google Patents
Info
- Publication number
- JP2024520205A5 JP2024520205A5 JP2023571857A JP2023571857A JP2024520205A5 JP 2024520205 A5 JP2024520205 A5 JP 2024520205A5 JP 2023571857 A JP2023571857 A JP 2023571857A JP 2023571857 A JP2023571857 A JP 2023571857A JP 2024520205 A5 JP2024520205 A5 JP 2024520205A5
- Authority
- JP
- Japan
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163191905P | 2021-05-21 | 2021-05-21 | |
| US63/191,905 | 2021-05-21 | ||
| PCT/US2022/030335 WO2022246251A2 (en) | 2021-05-21 | 2022-05-20 | Compounds for modulating unc13a expression |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024520205A JP2024520205A (ja) | 2024-05-22 |
| JP2024520205A5 true JP2024520205A5 (https=) | 2025-05-26 |
| JPWO2022246251A5 JPWO2022246251A5 (https=) | 2025-05-26 |
Family
ID=84140868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023571857A Pending JP2024520205A (ja) | 2021-05-21 | 2022-05-20 | Ｕｎｃ１３ａの発現を調節するための化合物 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20240301415A1 (https=) |
| EP (1) | EP4341406A4 (https=) |
| JP (1) | JP2024520205A (https=) |
| WO (1) | WO2022246251A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2603454A (en) | 2020-12-09 | 2022-08-10 | Ucl Business Ltd | Novel therapeutics for the treatment of neurodegenerative disorders |
| CA3227115A1 (en) * | 2021-07-21 | 2023-01-26 | Wen-Hsuan Chang | Unc13a antisense oligonucleotides |
| GB202117758D0 (en) * | 2021-12-09 | 2022-01-26 | Ucl Business Ltd | Therapeutics for the treatment of neurodegenerative disorders |
| CN118974254A (zh) * | 2021-12-21 | 2024-11-15 | 豪夫迈·罗氏有限公司 | 靶向unc13a的反义寡核苷酸 |
| AU2023356317A1 (en) * | 2022-10-05 | 2025-05-15 | Trace Neuroscience, Inc. | Unc13a antisense oligonucleotides and uses thereof |
| WO2024178223A1 (en) * | 2023-02-24 | 2024-08-29 | Northwestern University | Antisense oligonucleotides for preventing unc13a misplicing |
| WO2024220746A2 (en) | 2023-04-21 | 2024-10-24 | Flagship Pioneering Innovations Vii, Llc | Rnai agents targeting fatty acid synthase and related methods |
| AU2024299328A1 (en) | 2023-07-21 | 2026-01-22 | Marrow Therapeutics, Inc. | Hematopoietic cell targeting conjugates and related methods |
| US20250263702A1 (en) | 2024-02-19 | 2025-08-21 | Flagship Pioneering Innovations Vii, Llc | Rnai agents targeting cideb and related methods |
| WO2025217275A2 (en) | 2024-04-10 | 2025-10-16 | Flagship Pioneering Innovations Vii, Llc | Immune cell targeted compositions and related methods |
| WO2026080323A1 (en) * | 2024-10-09 | 2026-04-16 | Quralis Corporation | Treatment of neurological diseases using modulators of unc13a gene transcripts |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1123038A (zh) * | 1993-05-11 | 1996-05-22 | 北卡罗来纳大学查珀尔希尔分校 | 阻止异常剪接的反义寡核苷酸及其使用方法 |
| US20060008800A1 (en) * | 2001-11-05 | 2006-01-12 | Christian Rosenmund | Unc-13 in the modulation of neurotransmission and secretion events |
| EP2305812A3 (en) * | 2002-11-14 | 2012-06-06 | Dharmacon, Inc. | Fuctional and hyperfunctional sirna |
| EP1752536A4 (en) * | 2004-05-11 | 2008-04-16 | Alphagen Co Ltd | POLYNUCLEOTIDE CAUSING RNA INTERFERENCE AND METHOD OF REGULATING GENE EXPRESSION WITH THE USE OF THE SAME |
| US20110195848A1 (en) * | 2010-01-08 | 2011-08-11 | Roopra Avtar S | Gene expression and breast cancer |
| US10517889B2 (en) * | 2017-09-08 | 2019-12-31 | Ionis Pharmaceuticals, Inc. | Modulators of SMAD7 expression |
| GB2603454A (en) * | 2020-12-09 | 2022-08-10 | Ucl Business Ltd | Novel therapeutics for the treatment of neurodegenerative disorders |
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2022
- 2022-05-20 WO PCT/US2022/030335 patent/WO2022246251A2/en not_active Ceased
- 2022-05-20 JP JP2023571857A patent/JP2024520205A/ja active Pending
- 2022-05-20 US US18/562,543 patent/US20240301415A1/en active Pending
- 2022-05-20 EP EP22805616.4A patent/EP4341406A4/en active Pending