JP2024504377A5 - - Google Patents

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Publication number
JP2024504377A5
JP2024504377A5 JP2023544331A JP2023544331A JP2024504377A5 JP 2024504377 A5 JP2024504377 A5 JP 2024504377A5 JP 2023544331 A JP2023544331 A JP 2023544331A JP 2023544331 A JP2023544331 A JP 2023544331A JP 2024504377 A5 JP2024504377 A5 JP 2024504377A5
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JP
Japan
Application number
JP2023544331A
Other languages
Japanese (ja)
Other versions
JPWO2022159712A5 (https=
JP2024504377A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/013323 external-priority patent/WO2022159712A1/en
Publication of JP2024504377A publication Critical patent/JP2024504377A/ja
Publication of JPWO2022159712A5 publication Critical patent/JPWO2022159712A5/ja
Publication of JP2024504377A5 publication Critical patent/JP2024504377A5/ja
Pending legal-status Critical Current

Links

JP2023544331A 2021-01-22 2022-01-21 Dux4の発現を低減するための化合物及び方法 Pending JP2024504377A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163140674P 2021-01-22 2021-01-22
US63/140,674 2021-01-22
US202163217624P 2021-07-01 2021-07-01
US63/217,624 2021-07-01
US202163231559P 2021-08-10 2021-08-10
US63/231,559 2021-08-10
PCT/US2022/013323 WO2022159712A1 (en) 2021-01-22 2022-01-21 Compounds and methods for reducing dux4 expression

Publications (3)

Publication Number Publication Date
JP2024504377A JP2024504377A (ja) 2024-01-31
JPWO2022159712A5 JPWO2022159712A5 (https=) 2025-01-24
JP2024504377A5 true JP2024504377A5 (https=) 2025-01-24

Family

ID=82549881

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023544331A Pending JP2024504377A (ja) 2021-01-22 2022-01-21 Dux4の発現を低減するための化合物及び方法

Country Status (4)

Country Link
US (1) US20240336915A1 (https=)
EP (1) EP4281084A4 (https=)
JP (1) JP2024504377A (https=)
WO (1) WO2022159712A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12018087B2 (en) 2018-08-02 2024-06-25 Dyne Therapeutics, Inc. Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject
US20220193250A1 (en) 2018-08-02 2022-06-23 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US11638761B2 (en) 2021-07-09 2023-05-02 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy
US11969475B2 (en) 2021-07-09 2024-04-30 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
EP4370678A2 (en) * 2021-07-14 2024-05-22 Mirecule, Inc. Oligonucleotides and compositions thereof for neuromuscular disorders
EP4590308A2 (en) * 2022-09-23 2025-07-30 Ionis Pharmaceuticals, Inc. Compounds and methods for reducing mecp2 expression
JP2025532127A (ja) 2022-09-23 2025-09-29 アイオーニス ファーマシューティカルズ, インコーポレーテッド Mecp2発現を低減する化合物及び方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120225034A1 (en) * 2010-09-02 2012-09-06 Universite De Mons Agents useful in treating facioscapulohumeral muscular dystrophy
AU2012286994B2 (en) * 2011-07-25 2017-08-10 Nationwide Children's Hospital, Inc. Recombinant virus products and methods for inhibition of expression of DUX4
US10538763B2 (en) * 2015-01-16 2020-01-21 Ionis Pharmaceuticals, Inc. Compounds and methods for modulation of DUX4
EP3353301A1 (en) * 2015-09-21 2018-08-01 Association Institut de Myologie Antisense oligonucleotides and uses thereof
CA3099522C (en) * 2017-09-19 2024-10-08 The Governors Of The University Of Alberta GAPMERES AND METHODS OF USING THESE FOR THE TREATMENT OF MUSCULAR DYSTROPHY
AU2019218987B2 (en) * 2018-02-12 2025-04-24 Ionis Pharmaceuticals, Inc. Modified compounds and uses thereof
US20220195431A1 (en) * 2019-02-22 2022-06-23 Ionis Pharmaceuticals, Inc. Compounds and methods for reducing atxn3 expression
TW202104595A (zh) * 2019-03-29 2021-02-01 日商田邊三菱製藥股份有限公司 用來調節dux4的表現之化合物、方法及醫藥組成物

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