JP2023506181A5 - - Google Patents

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Publication number
JP2023506181A5
JP2023506181A5 JP2022535508A JP2022535508A JP2023506181A5 JP 2023506181 A5 JP2023506181 A5 JP 2023506181A5 JP 2022535508 A JP2022535508 A JP 2022535508A JP 2022535508 A JP2022535508 A JP 2022535508A JP 2023506181 A5 JP2023506181 A5 JP 2023506181A5
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JP
Japan
Prior art keywords
nucleotides
dsrna agent
agent according
modification
nucleotide
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Pending
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JP2022535508A
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English (en)
Japanese (ja)
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JP2023506181A (ja
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Priority claimed from PCT/US2020/064159 external-priority patent/WO2021119226A1/en
Publication of JP2023506181A publication Critical patent/JP2023506181A/ja
Publication of JP2023506181A5 publication Critical patent/JP2023506181A5/ja
Priority to JP2025093193A priority Critical patent/JP2025174957A/ja
Pending legal-status Critical Current

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JP2022535508A 2019-12-13 2020-12-10 ヒト第9染色体オープンリーディングフレーム72(C9ORF72)iRNA剤組成物およびその使用方法 Pending JP2023506181A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025093193A JP2025174957A (ja) 2019-12-13 2025-06-04 ヒト第9染色体オープンリーディングフレーム72(C9ORF72)iRNA剤組成物およびその使用方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962947768P 2019-12-13 2019-12-13
US201962947605P 2019-12-13 2019-12-13
US62/947,605 2019-12-13
US62/947,768 2019-12-13
PCT/US2020/064159 WO2021119226A1 (en) 2019-12-13 2020-12-10 Human chromosome 9 open reading frame 72 (c9orf72) irna agent compositions and methods of use thereof

Related Child Applications (1)

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JP2025093193A Division JP2025174957A (ja) 2019-12-13 2025-06-04 ヒト第9染色体オープンリーディングフレーム72(C9ORF72)iRNA剤組成物およびその使用方法

Publications (2)

Publication Number Publication Date
JP2023506181A JP2023506181A (ja) 2023-02-15
JP2023506181A5 true JP2023506181A5 (https=) 2023-12-15

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ID=74004172

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Application Number Title Priority Date Filing Date
JP2022535508A Pending JP2023506181A (ja) 2019-12-13 2020-12-10 ヒト第9染色体オープンリーディングフレーム72(C9ORF72)iRNA剤組成物およびその使用方法
JP2025093193A Pending JP2025174957A (ja) 2019-12-13 2025-06-04 ヒト第9染色体オープンリーディングフレーム72(C9ORF72)iRNA剤組成物およびその使用方法

Family Applications After (1)

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JP2025093193A Pending JP2025174957A (ja) 2019-12-13 2025-06-04 ヒト第9染色体オープンリーディングフレーム72(C9ORF72)iRNA剤組成物およびその使用方法

Country Status (15)

Country Link
US (1) US20230114649A1 (https=)
EP (1) EP4073251A1 (https=)
JP (2) JP2023506181A (https=)
KR (1) KR20220115995A (https=)
CN (1) CN115151641A (https=)
AU (1) AU2020402885A1 (https=)
BR (1) BR112022011417A2 (https=)
CA (1) CA3164599A1 (https=)
CL (2) CL2022001503A1 (https=)
CO (1) CO2022009787A2 (https=)
IL (1) IL293824A (https=)
MX (1) MX2022006433A (https=)
PH (1) PH12022551394A1 (https=)
TW (2) TW202548016A (https=)
WO (1) WO2021119226A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022528487A (ja) * 2019-03-29 2022-06-13 ユニバーシティ・オブ・マサチューセッツ C9orf72のオリゴヌクレオチドベースの調節
US11629347B2 (en) 2019-05-06 2023-04-18 University Of Massachusetts Anti-C9ORF72 oligonucleotides and related methods
WO2021195510A1 (en) 2020-03-27 2021-09-30 University Of Massachusetts Dual-acting sirna based modulation of c9orf72
EP4347822A2 (en) 2021-06-04 2024-04-10 Alnylam Pharmaceuticals, Inc. Human chromosome 9 open reading frame 72 (c9orf72) irna agent compositions and methods of use thereof
WO2022271972A1 (en) * 2021-06-23 2022-12-29 Alnylam Pharmaceuticals, Inc. Irna compositions and methods for silencing filamin a (flna)
TW202328449A (zh) 2021-09-24 2023-07-16 美商艾拉倫製藥公司 微管相關蛋白TAU(MAPT)iRNA試劑組合物及其使用方法
WO2024036343A2 (en) * 2022-08-12 2024-02-15 University Of Miami Synergistic nucleic acid based therapeutics and methods of use for treating genetic disorders
CN120035669A (zh) * 2022-09-28 2025-05-23 阿塔兰塔治疗公司 用于治疗神经系统病症的组合物和方法
KR20250116795A (ko) 2022-11-14 2025-08-01 리제너론 파마슈티칼스 인코포레이티드 별아교세포로의 섬유아세포 성장 인자 수용체 3-매개된 전달을 위한 조성물 및 방법

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