JP2024539596A5 - - Google Patents
Info
- Publication number
- JP2024539596A5 JP2024539596A5 JP2024520945A JP2024520945A JP2024539596A5 JP 2024539596 A5 JP2024539596 A5 JP 2024539596A5 JP 2024520945 A JP2024520945 A JP 2024520945A JP 2024520945 A JP2024520945 A JP 2024520945A JP 2024539596 A5 JP2024539596 A5 JP 2024539596A5
- Authority
- JP
- Japan
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163253516P | 2021-10-07 | 2021-10-07 | |
| US63/253,516 | 2021-10-07 | ||
| US202263317743P | 2022-03-08 | 2022-03-08 | |
| US63/317,743 | 2022-03-08 | ||
| PCT/US2022/077740 WO2023064707A1 (en) | 2021-10-07 | 2022-10-07 | Compounds and methods for reducing tau expression |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024539596A JP2024539596A (ja) | 2024-10-29 |
| JP2024539596A5 true JP2024539596A5 (https=) | 2025-10-14 |
| JPWO2023064707A5 JPWO2023064707A5 (https=) | 2025-10-14 |
Family
ID=85988949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024520945A Pending JP2024539596A (ja) | 2021-10-07 | 2022-10-07 | タウ発現を低減するための化合物及び方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20250340872A1 (https=) |
| EP (1) | EP4413138A4 (https=) |
| JP (1) | JP2024539596A (https=) |
| WO (1) | WO2023064707A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4448765A1 (en) | 2021-12-13 | 2024-10-23 | Eli Lilly and Company | Mapt rna interference agents |
| WO2025027577A1 (en) * | 2023-08-02 | 2025-02-06 | Consejo Nacional De Investigaciones Científicas Y Técnicas (Conicet) | Micrornas designed against the microtubule-associated protein tau for the treatment of tauopathies |
| KR20260051070A (ko) | 2023-08-10 | 2026-04-15 | 하네스 테라퓨틱스 리미티드 | 기능적 핵산 |
| GB202401412D0 (en) | 2024-02-02 | 2024-03-20 | Harness Therapeutics Ltd | Functional nucleic acid |
| US12551569B2 (en) | 2024-03-31 | 2026-02-17 | Arrowhead Pharmaceuticals, Inc. | RNAi agents for inhibiting expression of microtubule associated protein tau (MAPT), compositions thereof, and methods of use |
| WO2026002277A1 (zh) * | 2024-06-28 | 2026-01-02 | 艾码生物科技(南京)有限公司 | 靶向Tau的RNA干扰方法、核酸及其应用 |
| WO2026010722A1 (en) * | 2024-07-03 | 2026-01-08 | Voyager Therapeutics, Inc. | Compositions and methods for regulating mapt |
| WO2026021537A1 (en) * | 2024-07-26 | 2026-01-29 | Qilu Pharmaceutical Co., Ltd. | iRNA COMPOSITION AND METHOD OF USING SAME |
| CN118979036B (zh) * | 2024-08-01 | 2025-08-19 | 北京尧景基因技术有限公司 | 抑制APP基因表达的siRNA及其缀合物和应用 |
| CN121780524A (zh) * | 2024-08-02 | 2026-04-03 | 北京尧景基因技术有限公司 | 抑制MAPT基因表达的siRNA及其缀合物和应用 |
| WO2026067655A1 (zh) * | 2024-09-26 | 2026-04-02 | 大睿生物医药科技(上海)有限公司 | 调控TAU表达的dsRNA分子 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040241854A1 (en) * | 2002-08-05 | 2004-12-02 | Davidson Beverly L. | siRNA-mediated gene silencing |
| TWI772856B (zh) * | 2013-07-19 | 2022-08-01 | 美商百健Ｍａ公司 | 用於調節τ蛋白表現之組合物 |
| AU2016215155A1 (en) * | 2015-02-04 | 2017-08-17 | F. Hoffmann-La Roche Ag | Tau antisense oligomers and uses thereof |
| ES2963428T3 (es) * | 2016-09-29 | 2024-03-27 | Biogen Ma Inc | Compuestos y métodos para reducir la expresión de Tau |
| AU2021238319A1 (en) * | 2020-03-18 | 2022-10-06 | University Of Massachusetts | Oligonucleotides for MAPT modulation |
| AU2021246024A1 (en) * | 2020-03-30 | 2022-10-27 | Alnylam Pharmaceuticals, Inc. | Microtubule associated protein Tau (MAPT) iRNA agent compositions and methods of use thereof |
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2022
- 2022-10-07 US US18/699,132 patent/US20250340872A1/en active Pending
- 2022-10-07 EP EP22881922.3A patent/EP4413138A4/en active Pending
- 2022-10-07 WO PCT/US2022/077740 patent/WO2023064707A1/en not_active Ceased
- 2022-10-07 JP JP2024520945A patent/JP2024539596A/ja active Pending