JP2024521092A5 - - Google Patents

Info

Publication number
JP2024521092A5
JP2024521092A5 JP2023571661A JP2023571661A JP2024521092A5 JP 2024521092 A5 JP2024521092 A5 JP 2024521092A5 JP 2023571661 A JP2023571661 A JP 2023571661A JP 2023571661 A JP2023571661 A JP 2023571661A JP 2024521092 A5 JP2024521092 A5 JP 2024521092A5
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JP
Japan
Prior art keywords
target
salt
compound
moi
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023571661A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024521092A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/030070 external-priority patent/WO2022246086A1/en
Publication of JP2024521092A publication Critical patent/JP2024521092A/ja
Publication of JP2024521092A5 publication Critical patent/JP2024521092A5/ja
Pending legal-status Critical Current

Links

JP2023571661A 2021-05-19 2022-05-19 細胞傷害性薬剤を送達するためのmates技術を使用する抗体薬物コンジュゲート Pending JP2024521092A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163190703P 2021-05-19 2021-05-19
US63/190,703 2021-05-19
PCT/US2022/030070 WO2022246086A1 (en) 2021-05-19 2022-05-19 Antibody drug conjugates using mates technology for delivering cytotoxic agents

Publications (2)

Publication Number Publication Date
JP2024521092A JP2024521092A (ja) 2024-05-28
JP2024521092A5 true JP2024521092A5 (https=) 2025-05-26

Family

ID=84141792

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023571661A Pending JP2024521092A (ja) 2021-05-19 2022-05-19 細胞傷害性薬剤を送達するためのmates技術を使用する抗体薬物コンジュゲート

Country Status (12)

Country Link
US (1) US20250108124A1 (https=)
EP (1) EP4340859A4 (https=)
JP (1) JP2024521092A (https=)
KR (1) KR20240012381A (https=)
CN (1) CN117412761A (https=)
AU (1) AU2022277698A1 (https=)
BR (1) BR112023023525A2 (https=)
CA (1) CA3219550A1 (https=)
IL (1) IL307884A (https=)
MX (1) MX2023013270A (https=)
PH (1) PH12023553153A1 (https=)
WO (1) WO2022246086A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2023013274A (es) * 2021-05-17 2023-11-30 Biohaven Therapeutics Ltd Composiciones que incluyen potenciadores de tratamientos conjugados.
EP4704910A1 (en) * 2023-04-23 2026-03-11 Biohaven Therapeutics Ltd. Antibody-drug conjugates for delivering cytotoxic agents

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2478912B1 (en) * 2003-11-06 2016-08-31 Seattle Genetics, Inc. Auristatin conjugates with anti-HER2 or anti-CD22 antibodies and their use in therapy
JP2009541275A (ja) * 2006-06-22 2009-11-26 ノボ・ノルデイスク・エー/エス 二重特異性抗体の生産
EP2497775A1 (en) * 2011-03-11 2012-09-12 Ruprecht-Karls-Universität Heidelberg Ferrocene-based compounds and their use as ROS regulating prodrugs
CN102936281B (zh) * 2012-10-25 2013-12-25 浙江大学 一种rTRAIL突变体及其海兔毒素偶联物
EP3193940A1 (en) * 2014-09-10 2017-07-26 Medimmune Limited Pyrrolobenzodiazepines and conjugates thereof
AU2015339012B2 (en) * 2014-10-31 2020-11-05 Abbvie Biotherapeutics Inc. Anti-CS1 antibodies and antibody drug conjugates
SI3280441T1 (sl) * 2015-04-07 2022-01-31 Alector Llc Protitelesa anti-sortilin in metoda njihove uporabe
AU2018259856B2 (en) * 2017-04-28 2025-05-01 Ajinomoto Co., Inc. Compound having substance that has affinity for soluble protein, cleavable moiety, and reactive group, or salt thereof
US10953107B2 (en) * 2018-06-15 2021-03-23 Trustees Of Boston University Polypeptide compositions and methods for site-specific targeting of therapeutic agents
JP2022513198A (ja) * 2018-12-10 2022-02-07 ジェネンテック, インコーポレイテッド Fc含有タンパク質への部位特異的コンジュゲーションのための光架橋性ペプチド
US20230028880A1 (en) * 2019-07-03 2023-01-26 Biohaven Therapeutics Ltd. Cd38-binding agents and uses thereof
JP2023501720A (ja) * 2019-11-18 2023-01-18 クレオ ファーマシューティカルズ, インコーポレイテッド 指向性コンジュゲーション技術

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