JP2024512986A5 - - Google Patents
Info
- Publication number
- JP2024512986A5 JP2024512986A5 JP2023559766A JP2023559766A JP2024512986A5 JP 2024512986 A5 JP2024512986 A5 JP 2024512986A5 JP 2023559766 A JP2023559766 A JP 2023559766A JP 2023559766 A JP2023559766 A JP 2023559766A JP 2024512986 A5 JP2024512986 A5 JP 2024512986A5
- Authority
- JP
- Japan
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163167915P | 2021-03-30 | 2021-03-30 | |
| EP21305405.9 | 2021-03-30 | ||
| EP21305405 | 2021-03-30 | ||
| US63/167,915 | 2021-03-30 | ||
| PCT/EP2022/058402 WO2022207699A1 (en) | 2021-03-30 | 2022-03-30 | Enzyme-triggered self-reacting linker having improved physicochemical and pharmacological properties |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024512986A JP2024512986A (ja) | 2024-03-21 |
| JPWO2022207699A5 JPWO2022207699A5 (https=) | 2025-04-02 |
| JP2024512986A5 true JP2024512986A5 (https=) | 2025-04-02 |
Family
ID=81580241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023559766A Pending JP2024512986A (ja) | 2021-03-30 | 2022-03-30 | 改良された物理化学的特性および薬理学的特性を有する酵素トリガー自己反応性リンカー |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20240216525A1 (https=) |
| EP (1) | EP4313157A1 (https=) |
| JP (1) | JP2024512986A (https=) |
| KR (1) | KR20230165288A (https=) |
| AU (1) | AU2022248565A1 (https=) |
| BR (1) | BR112023019495A2 (https=) |
| CA (1) | CA3215279A1 (https=) |
| IL (1) | IL306050A (https=) |
| MX (1) | MX2023011630A (https=) |
| WO (1) | WO2022207699A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20240038138A (ko) | 2020-07-13 | 2024-03-22 | 리제너론 파마슈티칼스 인코포레이티드 | 단백질에서 글루타민 잔기에 접합된 캄토테신 유사체 및 그의 용도 |
| CA3241734A1 (en) * | 2022-01-12 | 2023-07-20 | Amy Han | Camptothecin analogs conjugated to a glutamine residue in a protein, and their use |
| CR20240375A (es) * | 2022-03-11 | 2025-01-06 | Mablink Bioscience | Conjugados anticuerpo-fármaco y sus usos |
| CN120882431A (zh) * | 2023-01-11 | 2025-10-31 | 金麦安博股份有限公司 | 接头、药物接头及其缀合物和使用它们的方法 |
| AU2024263367A1 (en) * | 2023-04-27 | 2025-11-13 | CSPC Megalith Biopharmaceutical Co., Ltd. | Antibody-drug conjugate |
| CN119212735A (zh) * | 2023-04-27 | 2024-12-27 | 石药集团巨石生物制药有限公司 | 一种抗体药物偶联物 |
| EP4512427A1 (en) | 2023-08-25 | 2025-02-26 | Mablink Bioscience | Antibody-drug conjugates based on molecular glue degraders and uses thereof |
| EP4534102A1 (en) | 2023-10-02 | 2025-04-09 | Eli Lilly and Company | Antibody drug conjugate (adc) targeting nectin 4 and comprising an exatecan payload |
| EP4534101A1 (en) | 2023-10-02 | 2025-04-09 | Eli Lilly and Company | Antibody drug conjugate (adc) targeting nectin 4 and comprising an exatecan payload |
| FR3155708A1 (fr) * | 2023-11-27 | 2025-05-30 | Skymab Biotherapeutics | Conjugue anticorps-medicament et ses utilisations |
| FR3155709A1 (fr) * | 2023-11-27 | 2025-05-30 | Skymab Biotherapeutics | Conjugue anticorps-medicament et ses utilisations |
| EP4566631A1 (en) | 2023-12-06 | 2025-06-11 | Heidelberg Pharma Research GmbH | New antibody drug conjugate as well as methods of production and uses thereof |
| WO2025230926A1 (en) * | 2024-04-29 | 2025-11-06 | Obi Pharma, Inc. | Improved linker-payloads for antibody conjugation, pharmaceutical compositions and applications thereof |
| WO2026076215A1 (en) * | 2024-10-03 | 2026-04-09 | Solve Therapeutics, Inc. | Conjugates and uses thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2960153B1 (fr) | 2010-05-20 | 2012-08-17 | Centre Nat Rech Scient | Nouveaux bras autoreactifs et prodrogues les comprenant |
| KR102847350B1 (ko) | 2015-11-25 | 2025-08-19 | 주식회사 리가켐바이오사이언스 | 분지된 링커를 포함하는 항체-약물 접합체 및 이의 제조방법 |
| JP7381478B2 (ja) | 2017-10-23 | 2023-11-15 | マブリンク ビオシオンス | 単一分子量ポリサルコシンを含むリガンド－薬物－複合体 |
-
2022
- 2022-03-30 US US18/285,175 patent/US20240216525A1/en active Pending
- 2022-03-30 EP EP22720929.3A patent/EP4313157A1/en active Pending
- 2022-03-30 BR BR112023019495A patent/BR112023019495A2/pt unknown
- 2022-03-30 JP JP2023559766A patent/JP2024512986A/ja active Pending
- 2022-03-30 WO PCT/EP2022/058402 patent/WO2022207699A1/en not_active Ceased
- 2022-03-30 AU AU2022248565A patent/AU2022248565A1/en active Pending
- 2022-03-30 IL IL306050A patent/IL306050A/en unknown
- 2022-03-30 MX MX2023011630A patent/MX2023011630A/es unknown
- 2022-03-30 KR KR1020237037385A patent/KR20230165288A/ko active Pending
- 2022-03-30 CA CA3215279A patent/CA3215279A1/en active Pending
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