JP2024505595A5 - - Google Patents

Info

Publication number
JP2024505595A5
JP2024505595A5 JP2023547811A JP2023547811A JP2024505595A5 JP 2024505595 A5 JP2024505595 A5 JP 2024505595A5 JP 2023547811 A JP2023547811 A JP 2023547811A JP 2023547811 A JP2023547811 A JP 2023547811A JP 2024505595 A5 JP2024505595 A5 JP 2024505595A5
Authority
JP
Japan
Prior art keywords
alkyl
hydrogen
alkyl groups
tolyl
piperidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023547811A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024505595A (ja
Filing date
Publication date
Priority claimed from PCT/CN2021/076366 external-priority patent/WO2022170519A1/en
Application filed filed Critical
Publication of JP2024505595A publication Critical patent/JP2024505595A/ja
Publication of JP2024505595A5 publication Critical patent/JP2024505595A5/ja
Pending legal-status Critical Current

Links

JP2023547811A 2021-02-09 2022-02-09 Trpm8アクチベーターとしての有機化合物 Pending JP2024505595A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/CN2021/076366 WO2022170519A1 (en) 2021-02-09 2021-02-09 Organic compounds
CNPCT/CN2021/076366 2021-02-09
PCT/EP2022/053085 WO2022171653A1 (en) 2021-02-09 2022-02-09 Organic compounds as trpm8 activators

Publications (2)

Publication Number Publication Date
JP2024505595A JP2024505595A (ja) 2024-02-06
JP2024505595A5 true JP2024505595A5 (https=) 2025-02-06

Family

ID=80447119

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023547811A Pending JP2024505595A (ja) 2021-02-09 2022-02-09 Trpm8アクチベーターとしての有機化合物

Country Status (6)

Country Link
US (1) US20240139087A1 (https=)
EP (1) EP4291553A1 (https=)
JP (1) JP2024505595A (https=)
CN (1) CN116867775A (https=)
MX (1) MX2023008005A (https=)
WO (2) WO2022170519A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120129464A (zh) 2022-10-27 2025-06-10 弗门尼舍有限公司 黄酮类化合物及其用途
EP4608172A1 (en) 2022-12-22 2025-09-03 Firmenich SA Natural sweetener compositions and uses thereof
CN120417784A (zh) 2022-12-22 2025-08-01 弗门尼舍有限公司 含烷基乳酸酯的天然甜味剂组合物及其用途
JP2026511252A (ja) 2023-03-28 2026-04-10 フイルメニツヒ ソシエテ アノニム 味改変組成物およびその使用
WO2025202256A1 (en) * 2024-03-28 2025-10-02 Firmenich Sa Cooling composition

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3988433A (en) 1973-08-10 1976-10-26 The Procter & Gamble Company Oral compositions for preventing or removing stains from teeth
US4083955A (en) 1975-04-02 1978-04-11 The Procter & Gamble Company Processes and compositions for remineralization of dental enamel
US4528180A (en) 1983-03-01 1985-07-09 Schaeffer Hans A Dental preparation, article and method for storage and delivery thereof
US4849213A (en) 1983-03-01 1989-07-18 Schaeffer Hans A Dental preparation, article and method for storage and delivery therof
US5198220A (en) 1989-11-17 1993-03-30 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
US5213790A (en) 1991-10-23 1993-05-25 The Procter & Gamble Co. Methods of reducing plaque and gingivitis with reduced staining
US5145666A (en) 1991-10-23 1992-09-08 The Proctor & Gamble Co. Methods of reducing plaque and gingivitis with reduced staining
US5281410A (en) 1991-10-23 1994-01-25 The Proctor & Gamble Company Methods of reducing plaque and gingivitis with reduced staining
US5242910A (en) 1992-10-13 1993-09-07 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
GB0704163D0 (en) 2007-03-02 2007-04-11 Quest Int Serv Bv Compositions comprising a physiological coolant
EP2346475B2 (en) 2008-11-20 2023-04-19 The Procter & Gamble Company Personal care compositions providing enhanced cooling sensation
CN103201279A (zh) * 2010-11-05 2013-07-10 赛诺米克斯公司 作为trpm8的调节剂有用的化合物
CN108473484B (zh) * 2015-10-01 2021-06-29 弗门尼舍公司 可用作trpm8调节剂的化合物
US20160339026A1 (en) * 2015-10-02 2016-11-24 Senomyx, Inc. Topical compositions comprising modulators of trpm8
ES2898259T3 (es) * 2017-07-14 2022-03-04 Firmenich & Cie Composiciones refrigerantes que contienen una amida y un alquil-lactato
ES2967435T3 (es) * 2017-08-31 2024-04-30 Basf Se Uso de principios activos refrescantes fisiológicos y productos que contienen dichos principios activos
JP7487100B2 (ja) 2017-12-21 2024-05-20 フイルメニツヒ ソシエテ アノニム 清涼および風味増強組成物
EP4045491A1 (en) 2019-10-17 2022-08-24 Givaudan SA Substituted azacyles as trmp8 modulators

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