JP2024153803A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2024153803A5 JP2024153803A5 JP2024123110A JP2024123110A JP2024153803A5 JP 2024153803 A5 JP2024153803 A5 JP 2024153803A5 JP 2024123110 A JP2024123110 A JP 2024123110A JP 2024123110 A JP2024123110 A JP 2024123110A JP 2024153803 A5 JP2024153803 A5 JP 2024153803A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- seq
- antibody
- cancer
- killing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562184018P | 2015-06-24 | 2015-06-24 | |
| US62/184,018 | 2015-06-24 | ||
| US201562249546P | 2015-11-02 | 2015-11-02 | |
| US62/249,546 | 2015-11-02 | ||
| US201562250566P | 2015-11-04 | 2015-11-04 | |
| US62/250,566 | 2015-11-04 | ||
| US201562263307P | 2015-12-04 | 2015-12-04 | |
| US62/263,307 | 2015-12-04 | ||
| US201662331489P | 2016-05-04 | 2016-05-04 | |
| US62/331,489 | 2016-05-04 | ||
| PCT/US2016/039165 WO2016210223A1 (en) | 2015-06-24 | 2016-06-24 | Immune modulation and treatment of solid tumors with antibodies that specifically bind cd38 |
| JP2017566768A JP7041519B2 (ja) | 2015-06-24 | 2016-06-24 | Ｃｄ３８を特異的に結合する抗体による免疫調節及び固形腫瘍の治療 |
| JP2022015442A JP7532428B2 (ja) | 2015-06-24 | 2022-02-03 | Ｃｄ３８を特異的に結合する抗体による免疫調節及び固形腫瘍の治療 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022015442A Division JP7532428B2 (ja) | 2015-06-24 | 2022-02-03 | Ｃｄ３８を特異的に結合する抗体による免疫調節及び固形腫瘍の治療 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024153803A JP2024153803A (ja) | 2024-10-29 |
| JP2024153803A5 true JP2024153803A5 (enExample) | 2025-03-18 |
Family
ID=57586547
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017566768A Active JP7041519B2 (ja) | 2015-06-24 | 2016-06-24 | Ｃｄ３８を特異的に結合する抗体による免疫調節及び固形腫瘍の治療 |
| JP2022015442A Active JP7532428B2 (ja) | 2015-06-24 | 2022-02-03 | Ｃｄ３８を特異的に結合する抗体による免疫調節及び固形腫瘍の治療 |
| JP2024123110A Pending JP2024153803A (ja) | 2015-06-24 | 2024-07-30 | Ｃｄ３８を特異的に結合する抗体による免疫調節及び固形腫瘍の治療 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017566768A Active JP7041519B2 (ja) | 2015-06-24 | 2016-06-24 | Ｃｄ３８を特異的に結合する抗体による免疫調節及び固形腫瘍の治療 |
| JP2022015442A Active JP7532428B2 (ja) | 2015-06-24 | 2022-02-03 | Ｃｄ３８を特異的に結合する抗体による免疫調節及び固形腫瘍の治療 |
Country Status (37)
Families Citing this family (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3312196B1 (en) * | 2005-03-23 | 2019-07-17 | Genmab A/S | Antibodies against cd38 for treatment of multiple myeloma |
| EP3613774A1 (en) | 2010-06-09 | 2020-02-26 | Genmab A/S | Antibodies against human cd38 |
| US12466897B2 (en) | 2011-10-10 | 2025-11-11 | Xencor, Inc. | Heterodimeric human IgG1 polypeptides with isoelectric point modifications |
| CN105051069B (zh) | 2013-01-14 | 2019-12-10 | Xencor股份有限公司 | 新型异二聚体蛋白 |
| US11053316B2 (en) | 2013-01-14 | 2021-07-06 | Xencor, Inc. | Optimized antibody variable regions |
| US10858417B2 (en) | 2013-03-15 | 2020-12-08 | Xencor, Inc. | Heterodimeric proteins |
| US9603927B2 (en) | 2014-02-28 | 2017-03-28 | Janssen Biotech, Inc. | Combination therapies with anti-CD38 antibodies |
| US9732154B2 (en) | 2014-02-28 | 2017-08-15 | Janssen Biotech, Inc. | Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia |
| PL3122173T5 (pl) | 2014-03-26 | 2024-08-05 | Scr Engineers Ltd | System lokalizacji żywego inwentarza |
| KR102497443B1 (ko) | 2014-03-28 | 2023-02-08 | 젠코어 인코포레이티드 | Cd38 및 cd3에 결합하는 이중특이적 항체 |
| US10986817B2 (en) | 2014-09-05 | 2021-04-27 | Intervet Inc. | Method and system for tracking health in animal populations |
| US11071279B2 (en) | 2014-09-05 | 2021-07-27 | Intervet Inc. | Method and system for tracking health in animal populations |
| EP3191187B1 (en) | 2014-09-09 | 2021-07-28 | Janssen Biotech, Inc. | Combination therapies with anti-cd38 antibodies |
| US10259887B2 (en) | 2014-11-26 | 2019-04-16 | Xencor, Inc. | Heterodimeric antibodies that bind CD3 and tumor antigens |
| CA2967426A1 (en) | 2014-11-26 | 2016-06-02 | Xencor, Inc. | Heterodimeric antibodies that bind cd3 and tumor antigens |
| BR112017011166A2 (pt) | 2014-11-26 | 2018-02-27 | Xencor, Inc. | anticorpos heterodiméricos que se ligam a cd3 e cd38 |
| JP6802791B2 (ja) | 2014-12-04 | 2020-12-23 | ヤンセン バイオテツク，インコーポレーテツド | 急性骨髄性白血病の治療のための抗ｃｄ３８抗体 |
| BR112017024877A2 (pt) | 2015-05-20 | 2019-09-17 | Janssen Biotech, Inc. | anticorpo anti-cd38 e seu uso no tratamento de amiloidose de cadeia leve e outras malignidades hematológicas positivas para cd38 |
| NZ777133A (en) | 2015-06-22 | 2025-05-02 | Janssen Biotech Inc | Combination therapies for heme malignancies with anti-cd38 antibodies and survivin inhibitors |
| US20170044265A1 (en) | 2015-06-24 | 2017-02-16 | Janssen Biotech, Inc. | Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38 |
| MD3827845T2 (ro) | 2015-11-03 | 2022-09-30 | Janssen Biotech Inc | Formulări subcutanate de anticorpi anti-CD38 și utilizări ale acestora |
| US10781261B2 (en) | 2015-11-03 | 2020-09-22 | Janssen Biotech, Inc. | Subcutaneous formulations of anti-CD38 antibodies and their uses |
| SMT202200118T1 (it) * | 2015-11-03 | 2022-05-12 | Janssen Biotech Inc | Anticorpi che legano specificamente pd-1 e loro usi |
| CN108699136B (zh) | 2015-12-07 | 2022-03-18 | Xencor股份有限公司 | 结合cd3和psma的异二聚抗体 |
| TWI781934B (zh) | 2016-05-27 | 2022-11-01 | 美商艾吉納斯公司 | 抗-tim-3抗體及其使用方法 |
| CA3026151A1 (en) | 2016-06-14 | 2017-12-21 | Xencor, Inc. | Bispecific checkpoint inhibitor antibodies |
| MX2018016265A (es) | 2016-06-28 | 2019-07-04 | Xencor Inc | Anticuerpos heterodimericos que se unen al receptor 2 de somatostatina. |
| US20190233533A1 (en) | 2016-06-28 | 2019-08-01 | Umc Utrecht Holding B.V. | Treatment Of IgE-Mediated Diseases With Antibodies That Specifically Bind CD38 |
| WO2018127608A1 (en) * | 2017-01-09 | 2018-07-12 | Biomunex Pharmaceuticals | A polypeptide linker for preparing multispecific antibodies |
| CN110536963A (zh) * | 2017-01-26 | 2019-12-03 | 桑格摩生物治疗股份有限公司 | B细胞工程改造 |
| EP3635002A1 (en) | 2017-06-08 | 2020-04-15 | Black Belt Therapeutics Limited | Cd38 modulating antibody |
| EP3635001A1 (en) * | 2017-06-08 | 2020-04-15 | Black Belt Therapeutics Limited | Cd38 modulating antibody |
| KR20250025513A (ko) * | 2017-06-08 | 2025-02-21 | 블랙 벨트 테라퓨틱스 리미티드 | Cd38 조정 항체 |
| EP3434692A1 (en) * | 2017-07-24 | 2019-01-30 | Encefa | Compounds which specifically binds to cd38 for use in the treatment of neurodegenerative diseases |
| KR102770110B1 (ko) | 2017-08-16 | 2025-02-20 | 블랙 벨트 테라퓨틱스 리미티드 | Cd38 항체 |
| US11542338B2 (en) | 2017-08-16 | 2023-01-03 | Black Belt Therapeutics Limited | CD38 modulating antibody |
| KR102770107B1 (ko) | 2017-08-16 | 2025-02-20 | 블랙 벨트 테라퓨틱스 리미티드 | Cd38 조정 항체 |
| MA50514A (fr) | 2017-10-31 | 2020-09-09 | Janssen Biotech Inc | Méthodes de traitement du myélome multiple à haut risque |
| KR20200085828A (ko) | 2017-11-08 | 2020-07-15 | 젠코어 인코포레이티드 | 신규의 항-pd-1 서열을 사용한 이중특이적 및 단일특이적 항체 |
| US12398209B2 (en) * | 2018-01-22 | 2025-08-26 | Janssen Biotech, Inc. | Methods of treating cancers with antagonistic anti-PD-1 antibodies |
| EP3773911A2 (en) | 2018-04-04 | 2021-02-17 | Xencor, Inc. | Heterodimeric antibodies that bind fibroblast activation protein |
| KR20210011919A (ko) | 2018-04-17 | 2021-02-02 | 셀덱스 쎄라퓨틱스, 인크. | 항-cd27 항체 및 항-pd-l1 항체 및 이중특이적 작제물 |
| US11832584B2 (en) | 2018-04-22 | 2023-12-05 | Vence, Corp. | Livestock management system and method |
| CN120865412A (zh) * | 2018-07-13 | 2025-10-31 | 根马布股份公司 | Cd38抗体变体及其用途 |
| WO2020012038A1 (en) | 2018-07-13 | 2020-01-16 | Genmab A/S | Trogocytosis-mediated therapy using cd38 antibodies |
| CN109265551B (zh) * | 2018-09-25 | 2020-09-15 | 华东师范大学 | Cd38抗体、嵌合抗原受体和药物 |
| EP3856784A4 (en) * | 2018-09-27 | 2022-10-19 | Musc Foundation for Research Development | PHARMACEUTICAL COMBINATIONS FOR THE TREATMENT OF CANCER |
| FR3086837B1 (fr) | 2018-10-03 | 2021-06-18 | Allflex Europe | Pince pour la manipulation d’un dispositif d’identification d’un animal et/ou de prelevement d’un tissu d’un animal comprenant des moyens de maintien a moyens d’actionnement deportes |
| WO2020075174A1 (en) | 2018-10-10 | 2020-04-16 | Scr Engineers Ltd | Livestock dry off method and device |
| WO2020160587A1 (en) | 2019-02-08 | 2020-08-13 | Allflex Australia Pty Ltd | Electronic animal tag reader |
| EP3921761B1 (en) | 2019-02-08 | 2024-09-18 | Allflex Australia Pty Ltd | Electronic animal identification tag reader synchronisation |
| AU2019428657B2 (en) | 2019-02-08 | 2025-10-23 | Allflex Australia Pty Ltd | Determining the location of an animal |
| US20200308297A1 (en) * | 2019-03-28 | 2020-10-01 | Janssen Biotech, Inc. | Clinically Proven Subcutaneous Pharmaceutical Compositions Comprising Anti-CD38 Antibodies and Their Uses |
| WO2021040540A1 (en) | 2019-08-28 | 2021-03-04 | Lic Automation Limited | Devices for analysis of a fluid |
| KR20220130724A (ko) | 2020-01-16 | 2022-09-27 | 젠맵 에이/에스 | Cd38 항체의 제제 및 그의 용도 |
| US11919956B2 (en) | 2020-05-14 | 2024-03-05 | Xencor, Inc. | Heterodimeric antibodies that bind prostate specific membrane antigen (PSMA) and CD3 |
| IL275518B (en) | 2020-06-18 | 2021-10-31 | Scr Eng Ltd | Animal tag |
| USD990062S1 (en) | 2020-06-18 | 2023-06-20 | S.C.R. (Engineers) Limited | Animal ear tag |
| USD990063S1 (en) | 2020-06-18 | 2023-06-20 | S.C.R. (Engineers) Limited | Animal ear tag |
| IL275812B (en) | 2020-07-01 | 2022-01-01 | Scr Eng Ltd | System and method for placing devices |
| JP7773528B2 (ja) | 2020-08-19 | 2025-11-19 | ゼンコア インコーポレイテッド | 抗ｃｄ２８組成物 |
| US11960957B2 (en) | 2020-11-25 | 2024-04-16 | Identigen Limited | System and method for tracing members of an animal population |
| EP4255929A2 (en) | 2020-12-02 | 2023-10-11 | Vib Vzw | An ltbr agonist in combination therapy against cancer |
| TW202235435A (zh) | 2021-01-14 | 2022-09-16 | 德商莫菲西斯公司 | 抗cd38抗體及其用途 |
| IL280374B2 (en) | 2021-01-24 | 2023-11-01 | Scr Eng Ltd | System and method for controlling animal marking |
| IL280744A (en) | 2021-02-09 | 2022-09-01 | Scr Eng Ltd | A system and method for determining animal population welfare |
| TW202302642A (zh) | 2021-03-01 | 2023-01-16 | 德商莫菲西斯公司 | 用於治療抗體介導移植物排斥用途之抗ｃｄ３８抗體 |
| CA3212665A1 (en) | 2021-03-09 | 2022-09-15 | Xencor, Inc. | Heterodimeric antibodies that bind cd3 and cldn6 |
| KR20230154311A (ko) | 2021-03-10 | 2023-11-07 | 젠코어 인코포레이티드 | Cd3 및 gpc3에 결합하는 이종이량체 항체 |
| CA206812S (en) | 2021-04-08 | 2023-04-11 | Chevillot Sas | Tag applicator for animals |
| CA206747S (en) | 2021-04-08 | 2024-12-30 | Chevillot Sas | Tag applicator for animals |
| IL283741A (en) | 2021-06-03 | 2022-07-01 | Scr Eng Ltd | A system and method for estimating greenhouse gas emissions in an environment that houses animals |
| IL310941A (en) * | 2021-08-25 | 2024-04-01 | Biograph 55 Inc | Methods for the treatment of cancer associated with immunosuppressive B cells |
| US20230330138A1 (en) * | 2022-04-14 | 2023-10-19 | Creative Medical Technologies, Inc. | Treatment of cartilage degeneration using myeloid suppressor cells and exosomes derived thereof |
| US12402596B2 (en) | 2022-05-03 | 2025-09-02 | S.C.R. (Engineers) Limited | Milk channel and feed inlet coupled thereto, and system and method for conserving wash fluid in a washing process for cleaning a milkmeter system |
| CN114805582B (zh) * | 2022-06-29 | 2022-10-04 | 上海恒润达生生物科技股份有限公司 | 抗Trop2纳米抗体及其用途 |
| EP4612177A1 (en) | 2022-10-31 | 2025-09-10 | Genmab A/S | Cd38 antibodies and uses thereof |
| WO2024126750A1 (en) * | 2022-12-15 | 2024-06-20 | F. Hoffmann-La Roche Ag | Methods for treating cancer |
Family Cites Families (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| WO1988001649A1 (en) | 1986-09-02 | 1988-03-10 | Genex Corporation | Single polypeptide chain binding molecules |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| US6172197B1 (en) | 1991-07-10 | 2001-01-09 | Medical Research Council | Methods for producing members of specific binding pairs |
| US5932448A (en) | 1991-11-29 | 1999-08-03 | Protein Design Labs., Inc. | Bispecific antibody heterodimers |
| ATE463573T1 (de) | 1991-12-02 | 2010-04-15 | Medimmune Ltd | Herstellung von autoantikörpern auf phagenoberflächen ausgehend von antikörpersegmentbibliotheken |
| DK0672142T3 (da) | 1992-12-04 | 2001-06-18 | Medical Res Council | Multivalente og multispecifikke bindingsproteiner samt fremstilling og anvendelse af disse |
| US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
| AUPO591797A0 (en) | 1997-03-27 | 1997-04-24 | Commonwealth Scientific And Industrial Research Organisation | High avidity polyvalent and polyspecific reagents |
| US6737056B1 (en) | 1999-01-15 | 2004-05-18 | Genentech, Inc. | Polypeptide variants with altered effector function |
| US7829693B2 (en) | 1999-11-24 | 2010-11-09 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for inhibiting expression of a target gene |
| US6833441B2 (en) | 2001-08-01 | 2004-12-21 | Abmaxis, Inc. | Compositions and methods for generating chimeric heteromultimers |
| EP1283053A1 (en) | 2001-08-09 | 2003-02-12 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Inhibitors of HER3 activity |
| IL149820A0 (en) | 2002-05-23 | 2002-11-10 | Curetech Ltd | Humanized immunomodulatory monoclonal antibodies for the treatment of neoplastic disease or immunodeficiency |
| AU2004218354B2 (en) | 2003-03-05 | 2009-10-01 | Halozyme, Inc. | Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof |
| US8597911B2 (en) | 2003-06-11 | 2013-12-03 | Chugai Seiyaku Kabushiki Kaisha | Process for producing antibodies |
| NZ548990A (en) | 2004-02-06 | 2009-06-26 | Morphosys Ag | Anti-CD38 human antibodies and uses therefor |
| EP3312196B1 (en) * | 2005-03-23 | 2019-07-17 | Genmab A/S | Antibodies against cd38 for treatment of multiple myeloma |
| TWI671403B (zh) | 2005-03-31 | 2019-09-11 | 中外製藥股份有限公司 | 控制組裝之多肽的製造方法 |
| ES2720160T3 (es) | 2005-05-09 | 2019-07-18 | Ono Pharmaceutical Co | Anticuerpos monoclonales humanos contra muerte programada 1(PD-1) y métodos para tratar el cáncer usando anticuerpos dirigidos contra PD-1 solos o junto con otras sustancias inmunoterapéuticas |
| US20090123950A1 (en) | 2005-05-24 | 2009-05-14 | Morphosys Ag | Generation And Profiling Of Fully Human Hucal Gold®-Derived Therapeutic Antibodies Specific For Human CD38 |
| KR20150139636A (ko) | 2005-10-12 | 2015-12-11 | 모르포시스 아게 | 인간 ｃｄ38에 특이적인 완전 인간 ｈｕｃａｌ ｇｏｌｄ-유도 치료 항체들의 생성 및 프로파일링 |
| ES2395969T3 (es) | 2006-03-24 | 2013-02-18 | Merck Patent Gmbh | Dominios de proteínas heterodiméricas genéticamente modificados |
| EP2035456A1 (en) | 2006-06-22 | 2009-03-18 | Novo Nordisk A/S | Production of bispecific antibodies |
| WO2008073160A2 (en) * | 2006-08-17 | 2008-06-19 | The Trustees Of Columbia University In The City Of New York | Methods for converting or inducing protective immunity |
| NZ576122A (en) * | 2006-09-26 | 2012-09-28 | Genmab As | Anti-cd38 plus corticosteroids plus a non-corticosteroid chemotherapeutic for treating tumors |
| EP1914242A1 (en) | 2006-10-19 | 2008-04-23 | Sanofi-Aventis | Novel anti-CD38 antibodies for the treatment of cancer |
| US20080226635A1 (en) | 2006-12-22 | 2008-09-18 | Hans Koll | Antibodies against insulin-like growth factor I receptor and uses thereof |
| EP2139924B1 (en) | 2007-03-29 | 2016-07-06 | Genmab A/S | Bispecific antibodies and methods for production thereof |
| JP5191537B2 (ja) | 2007-06-18 | 2013-05-08 | エム・エス・ディー・オス・ベー・フェー | ヒトのプログラムされたデスレセプターｐｄ−１に対する抗体 |
| ES2564523T3 (es) | 2007-12-19 | 2016-03-23 | Janssen Biotech, Inc. | Diseño y generación de bibliotecas de presentación en fago por pIX de novo humanas mediante fusión con pIX o pVII, vectores, anticuerpos y métodos |
| SI2235064T1 (sl) | 2008-01-07 | 2016-04-29 | Amgen Inc. | Metoda za izdelavo heterodimernih molekul - protitelesa fc z uporabo elektrostatičnih usmerjevalnih učinkov |
| JP5646457B2 (ja) | 2008-04-29 | 2014-12-24 | アッヴィ・インコーポレイテッド | 二重可変ドメイン免疫グロブリン及びその使用 |
| AR072999A1 (es) | 2008-08-11 | 2010-10-06 | Medarex Inc | Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos |
| BRPI0919377A2 (pt) | 2008-09-26 | 2016-09-27 | Dana Farber Cancer Inst Inc | anticorpo isolado ou um fragmento ligante de antígeno do memso, ácido nucleico isolado, vetor, célula hospedeira, composição farmacêutica, método de produzir o referido anticorpo ou fragmento, uso dos mesmos, e composição compreendendo o referido anticorpo ou fragmento |
| HUE065752T2 (hu) | 2008-12-09 | 2024-06-28 | Hoffmann La Roche | Anti-PD-L1 antitestek és felhasználásuk T-sejt funkció elõsegítésére |
| CN102459346B (zh) | 2009-04-27 | 2016-10-26 | 昂考梅德药品有限公司 | 制造异源多聚体分子的方法 |
| PT2504364T (pt) | 2009-11-24 | 2017-11-14 | Medimmune Ltd | Agentes de ligação direcionados contra b7-h1 |
| PL2560993T3 (pl) | 2010-04-20 | 2024-11-04 | Genmab A/S | Heterodimeryczne białka zawierające region FC przeciwciała i sposoby ich wytwarzania |
| CA2797981C (en) | 2010-05-14 | 2019-04-23 | Rinat Neuroscience Corporation | Heterodimeric proteins and methods for producing and purifying them |
| EP3613774A1 (en) | 2010-06-09 | 2020-02-26 | Genmab A/S | Antibodies against human cd38 |
| EP2420253A1 (en) | 2010-08-20 | 2012-02-22 | Leadartis, S.L. | Engineering multifunctional and multivalent molecules with collagen XV trimerization domain |
| AU2011325833C1 (en) | 2010-11-05 | 2017-07-13 | Zymeworks Bc Inc. | Stable heterodimeric antibody design with mutations in the Fc domain |
| JOP20210044A1 (ar) * | 2010-12-30 | 2017-06-16 | Takeda Pharmaceuticals Co | الأجسام المضادة لـ cd38 |
| JP6072771B2 (ja) | 2011-04-20 | 2017-02-01 | メディミューン，エルエルシー | Ｂ７−ｈ１およびｐｄ−１に結合する抗体およびその他の分子 |
| US9212224B2 (en) * | 2012-05-15 | 2015-12-15 | Bristol-Myers Squibb Company | Antibodies that bind PD-L1 and uses thereof |
| US9179480B2 (en) | 2012-07-24 | 2015-11-03 | Telefonaktiebolaget L M Ericsson (Publ) | Apparatus and method for dynamically selecting a random access response window value for use with random access procedures in a network |
| US9682143B2 (en) * | 2012-08-14 | 2017-06-20 | Ibc Pharmaceuticals, Inc. | Combination therapy for inducing immune response to disease |
| EP2914302B1 (en) * | 2012-11-05 | 2017-01-04 | MorphoSys AG | Radiolabelled antibody and uses thereof |
| FI3677591T3 (fi) | 2013-04-29 | 2023-04-03 | Teva Pharmaceuticals Australia Pty Ltd | Anti-cd38-vasta-aineet ja fuusiot heikennetylle interferonille alfa-2b |
| US20140356318A1 (en) * | 2013-05-28 | 2014-12-04 | Israel Barken | Adoptive cell therapy with specific regulatory lymphocytes |
| US9676853B2 (en) | 2013-05-31 | 2017-06-13 | Sorrento Therapeutics, Inc. | Antigen binding proteins that bind PD-1 |
| CA2919513A1 (en) * | 2013-07-15 | 2015-01-22 | Matthew J. Goldstein | Medical uses of cd38 agonists |
| EP3066125A2 (en) * | 2013-11-06 | 2016-09-14 | Boehringer Ingelheim International GmbH | Pharmaceutical combinations comprising cd33 antibodies and de-methylating agents |
| US9603927B2 (en) * | 2014-02-28 | 2017-03-28 | Janssen Biotech, Inc. | Combination therapies with anti-CD38 antibodies |
| JP7382695B2 (ja) * | 2020-07-09 | 2023-11-17 | パーカーエンジニアリング株式会社 | 塗料ミスト捕集装置 |
-
2016
- 2016-06-24 PE PE2017002833A patent/PE20181090A1/es unknown
- 2016-06-24 LT LTEPPCT/US2016/039165T patent/LT3313441T/lt unknown
- 2016-06-24 KR KR1020247032639A patent/KR20240150522A/ko active Pending
- 2016-06-24 EA EA201890131A patent/EA037548B1/ru unknown
- 2016-06-24 CN CN201680048975.9A patent/CN107921120A/zh active Pending
- 2016-06-24 EP EP16815351.8A patent/EP3313441B1/en active Active
- 2016-06-24 MA MA71262A patent/MA71262A/fr unknown
- 2016-06-24 KR KR1020187001612A patent/KR102713847B1/ko active Active
- 2016-06-24 WO PCT/US2016/039165 patent/WO2016210223A1/en not_active Ceased
- 2016-06-24 FI FIEP16815351.8T patent/FI3313441T3/fi active
- 2016-06-24 BR BR112017027990-8A patent/BR112017027990A2/pt not_active Application Discontinuation
- 2016-06-24 UA UAA201800631A patent/UA124799C2/uk unknown
- 2016-06-24 DK DK16815351.8T patent/DK3313441T5/da active
- 2016-06-24 AU AU2016281717A patent/AU2016281717B2/en active Active
- 2016-06-24 MX MX2018000261A patent/MX2018000261A/es unknown
- 2016-06-24 HR HRP20240338TT patent/HRP20240338T1/hr unknown
- 2016-06-24 MY MYPI2017704935A patent/MY193727A/en unknown
- 2016-06-24 MD MDE20180463T patent/MD3313441T2/ro unknown
- 2016-06-24 HU HUE16815351A patent/HUE066300T2/hu unknown
- 2016-06-24 US US15/191,808 patent/US20160376373A1/en not_active Abandoned
- 2016-06-24 PT PT168153518T patent/PT3313441T/pt unknown
- 2016-06-24 PL PL16815351.8T patent/PL3313441T3/pl unknown
- 2016-06-24 ES ES16815351T patent/ES2982292T3/es active Active
- 2016-06-24 SI SI201631806T patent/SI3313441T1/sl unknown
- 2016-06-24 SM SM20240127T patent/SMT202400127T1/it unknown
- 2016-06-24 CA CA2990620A patent/CA2990620A1/en active Pending
- 2016-06-24 RS RS20240308A patent/RS65347B1/sr unknown
- 2016-06-24 JP JP2017566768A patent/JP7041519B2/ja active Active
- 2016-06-24 EP EP24158614.8A patent/EP4385569A3/en active Pending
-
2017
- 2017-12-11 IL IL256248A patent/IL256248A/en unknown
- 2017-12-14 PH PH12017502311A patent/PH12017502311A1/en unknown
- 2017-12-19 CL CL2017003275A patent/CL2017003275A1/es unknown
- 2017-12-20 NI NI201700170A patent/NI201700170A/es unknown
- 2017-12-21 DO DO2017000305A patent/DOP2017000305A/es unknown
- 2017-12-22 CO CONC2017/0013332A patent/CO2017013332A2/es unknown
- 2017-12-22 SV SV2017005607A patent/SV2017005607A/es unknown
- 2017-12-26 GT GT201700286A patent/GT201700286A/es unknown
- 2017-12-26 EC ECIEPI201784878A patent/ECSP17084878A/es unknown
-
2018
- 2018-01-08 MX MX2021012133A patent/MX2021012133A/es unknown
- 2018-01-08 MX MX2021012134A patent/MX2021012134A/es unknown
- 2018-01-23 ZA ZA2018/00476A patent/ZA201800476B/en unknown
-
2019
- 2019-12-13 CL CL2019003657A patent/CL2019003657A1/es unknown
-
2022
- 2022-02-03 JP JP2022015442A patent/JP7532428B2/ja active Active
-
2024
- 2024-07-30 JP JP2024123110A patent/JP2024153803A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2024153803A5 (enExample) | ||
| FI3313441T3 (fi) | Kiinteiden kasvainten immunomodulaatio ja hoito spesifisesti cd38:aa sitovilla vasta-aineilla | |
| Chang et al. | Combination therapy with bispecific antibodies and PD-1 blockade enhances the antitumor potency of T cells | |
| JP2021155431A5 (enExample) | ||
| Xu et al. | Retargeting T cells to GD2 pentasaccharide on human tumors using bispecific humanized antibody | |
| JP7717686B2 (ja) | キメラｃｄ３融合タンパク質と抗ｃｄ３ベースの二重特異性ｔ細胞活性化エレメントの複合発現 | |
| Spear et al. | Strategies to genetically engineer T cells for cancer immunotherapy | |
| JP2020103301A5 (enExample) | ||
| FI3455259T3 (fi) | Anti-PD-1-vasta-aineiden ja sädehoidon yhdistelmä syövän hoitoon | |
| JP2019536430A5 (enExample) | ||
| JP2016528195A5 (enExample) | ||
| JP2019519499A5 (enExample) | ||
| JP2018531939A (ja) | 治療用化合物及び方法 | |
| JP6578604B2 (ja) | 固形がんの治療剤 | |
| JP2023071889A (ja) | Ｔｉｇｉｔおよびｐｄ－１／ｔｉｇｉｔ結合分子 | |
| CN110511278A (zh) | 抗b7-h6抗体、融合蛋白及其使用方法 | |
| RU2014101669A (ru) | Агенты, связывающие белки r-спондины (rspo), и способы их применения | |
| KR20200092302A (ko) | 다중-특이적 항체 및 이들의 제조 및 사용 방법 | |
| JP7689200B2 (ja) | 抗ｃｎｔｎ４特異的抗体及びその使用 | |
| Zhu et al. | Natural killer cell engagers: from bi‐specific to tri‐specific and tetra‐specific engagers for enhanced cancer immunotherapy | |
| JP2024016024A5 (enExample) | ||
| KR20190140756A (ko) | 자연 살상 세포에 결합하는 이중특이적 항체 및 이의 용도 | |
| JP2021530506A (ja) | 免疫チェックポイントを標的とする二重特異性抗体 | |
| Valent et al. | Cell-based and antibody-mediated immunotherapies directed against leukemic stem cells in acute myeloid leukemia: perspectives and open issues | |
| KR20210145179A (ko) | 스위치 가능한 키메라 항원 수용체-조작된 인간 자연 살해 세포 |