JP2016528195A5 - - Google Patents
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- JP2016528195A5 JP2016528195A5 JP2016523819A JP2016523819A JP2016528195A5 JP 2016528195 A5 JP2016528195 A5 JP 2016528195A5 JP 2016523819 A JP2016523819 A JP 2016523819A JP 2016523819 A JP2016523819 A JP 2016523819A JP 2016528195 A5 JP2016528195 A5 JP 2016528195A5
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- Japan
- Prior art keywords
- cancer
- pharmaceutical composition
- antibody
- cells
- antigen
- Prior art date
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Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361839170P | 2013-06-25 | 2013-06-25 | |
| US61/839,170 | 2013-06-25 | ||
| US201361874241P | 2013-09-05 | 2013-09-05 | |
| US61/874,241 | 2013-09-05 | ||
| US201361884771P | 2013-09-30 | 2013-09-30 | |
| US61/884,771 | 2013-09-30 | ||
| US201361907845P | 2013-11-22 | 2013-11-22 | |
| US61/907,845 | 2013-11-22 | ||
| PCT/US2014/043466 WO2014209802A1 (en) | 2013-06-25 | 2014-06-20 | Use of semaphorin-4d inhibitory molecules in combination with an immune modulating therapy to inhibit tumor growth and metastases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019129005A Division JP7021153B2 (ja) | 2013-06-25 | 2019-07-11 | 腫瘍成長および転移を阻害するための免疫調節療法との組み合わせでのセマフォリン－４ｄ阻害分子の使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016528195A JP2016528195A (ja) | 2016-09-15 |
| JP2016528195A5 true JP2016528195A5 (enExample) | 2017-07-27 |
| JP6611709B2 JP6611709B2 (ja) | 2019-11-27 |
Family
ID=52142579
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016523819A Active JP6611709B2 (ja) | 2013-06-25 | 2014-06-20 | 腫瘍成長および転移を阻害するための免疫調節療法との組み合わせでのセマフォリン−４ｄ阻害分子の使用 |
| JP2019129005A Active JP7021153B2 (ja) | 2013-06-25 | 2019-07-11 | 腫瘍成長および転移を阻害するための免疫調節療法との組み合わせでのセマフォリン－４ｄ阻害分子の使用 |
| JP2022015562A Active JP7356531B2 (ja) | 2013-06-25 | 2022-02-03 | 腫瘍成長および転移を阻害するための免疫調節療法との組み合わせでのセマフォリン－４ｄ阻害分子の使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019129005A Active JP7021153B2 (ja) | 2013-06-25 | 2019-07-11 | 腫瘍成長および転移を阻害するための免疫調節療法との組み合わせでのセマフォリン－４ｄ阻害分子の使用 |
| JP2022015562A Active JP7356531B2 (ja) | 2013-06-25 | 2022-02-03 | 腫瘍成長および転移を阻害するための免疫調節療法との組み合わせでのセマフォリン－４ｄ阻害分子の使用 |
Country Status (18)
| Country | Link |
|---|---|
| US (6) | US9828435B2 (enExample) |
| EP (2) | EP3656392A1 (enExample) |
| JP (3) | JP6611709B2 (enExample) |
| KR (2) | KR102291971B1 (enExample) |
| CN (1) | CN105492016B (enExample) |
| AU (2) | AU2014302812B2 (enExample) |
| BR (1) | BR112015032690B1 (enExample) |
| CA (2) | CA3098741A1 (enExample) |
| DK (1) | DK3013350T3 (enExample) |
| EA (1) | EA036591B1 (enExample) |
| ES (1) | ES2782834T3 (enExample) |
| IL (1) | IL243301B (enExample) |
| MX (1) | MX377858B (enExample) |
| NZ (1) | NZ631015A (enExample) |
| PL (1) | PL3013350T3 (enExample) |
| PT (1) | PT3013350T (enExample) |
| SG (2) | SG10201902380SA (enExample) |
| WO (1) | WO2014209802A1 (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3320920A1 (en) | 2009-05-08 | 2018-05-16 | Vaccinex, Inc. | Anti-cd100 antibodies and methods for using the same |
| EP2766093B1 (en) | 2011-10-11 | 2018-02-21 | Vaccinex, Inc. | Use of semaphorin-4d binding molecules for modulation of blood brain barrier permeability |
| US9090709B2 (en) | 2012-03-28 | 2015-07-28 | Vaccinex, Inc. | Anti-SEMA4D antibodies and epitopes |
| US9708601B2 (en) | 2012-04-26 | 2017-07-18 | Vaccinex, Inc. | Fusion proteins to facilitate selection of cells infected with specific immunoglobulin gene recombinant vaccinia virus |
| US10494440B2 (en) | 2012-05-11 | 2019-12-03 | Vaccinex, Inc. | Use of semaphorin-4D binding molecules to promote neurogenesis following stroke |
| EP3653212B1 (en) | 2012-12-20 | 2023-04-26 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| SG10201902380SA (en) | 2013-06-25 | 2019-04-29 | Vaccinex Inc | Use of semaphorin-4d inhibitory molecules in combination with an immune modulating therapy to inhibit tumor growth and metastases |
| NZ630881A (en) | 2013-10-10 | 2016-03-31 | Vaccinex Inc | Use of semaphorin-4d binding molecules for treatment of atherosclerosis |
| NZ630892A (en) | 2013-10-21 | 2016-03-31 | Vaccinex Inc | Use of semaphorin-4d binding molecules for treating neurodegenerative disorders |
| EP3136858A4 (en) * | 2014-05-02 | 2018-01-03 | Nitor Therapeutics | Guanosine as an immunepotentiator mediated through toll receptors |
| WO2017132541A1 (en) * | 2016-01-27 | 2017-08-03 | University Of Maryland, Baltimore | A method for monitoring cancer and for regulation of semaphorin 4d to improve cancer immunotherapy regimens |
| EP3213768A1 (en) | 2016-03-01 | 2017-09-06 | LODOCO CLINICAL Kft | Combination of low dose immune checkpoint blockade with high dose il-2 for treating metastatic cancer |
| EP3439675A4 (en) | 2016-04-08 | 2019-12-18 | Purdue Research Foundation | METHOD AND COMPOSITIONS FOR CAR-T CELL THERAPY |
| WO2017182706A1 (en) * | 2016-04-18 | 2017-10-26 | Faron Pharmaceuticals Oy | Diagnosis of immune_activation using clever-1, tnf-alpha and hla-dr binding agents |
| EP3445397B1 (en) | 2016-04-22 | 2022-11-09 | Vaccinex, Inc. | Integral membrane protein display on poxvirus extracellular enveloped virions |
| EP3473262A4 (en) * | 2016-06-16 | 2020-03-18 | The University Of Tokyo | PLEXIN BINDING REGULATOR |
| CA3032512C (en) | 2016-08-02 | 2025-05-06 | Vaccinex, Inc. | IMPROVED PROCESSES FOR PRODUCING POLYNUCLEOTIDE LIBRARIES IN VACCINE VIRUS/EUKARYOTIC CELLS |
| USD889258S1 (en) * | 2016-08-04 | 2020-07-07 | Carolin McKie | Beverage container identification marker kit |
| CA3036835A1 (en) * | 2016-09-16 | 2018-03-22 | The Brigham And Women's Hospital, Inc. | Klrg1 depletion therapy |
| WO2018071668A1 (en) * | 2016-10-12 | 2018-04-19 | Board Of Regents, The University Of Texas System | Methods and compositions for tusc2 immunotherapy |
| US11649288B2 (en) | 2017-02-07 | 2023-05-16 | Seattle Children's Hospital | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents |
| ES3010559T3 (en) | 2017-02-28 | 2025-04-03 | Endocyte Inc | Compositions and methods for car t cell therapy |
| PT3600419T (pt) | 2017-03-20 | 2023-11-16 | Vaccinex Inc | Tratamento do cancro com um anticorpo semaforina-4d em combinação com um agente modulador epigenético |
| JP2020517259A (ja) | 2017-04-19 | 2020-06-18 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | 操作された抗原受容体を発現する免疫細胞 |
| US11427634B2 (en) | 2017-05-05 | 2022-08-30 | Vaccinex, Inc. | Human anti-semaphorin 4D antibody |
| AU2019209428B2 (en) | 2018-01-22 | 2025-06-26 | Endocyte, Inc. | Methods of use for CAR T cells |
| CA3090089A1 (en) | 2018-02-06 | 2019-08-15 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Fluorescein-specific cars exhibiting optimal t cell function against fl-ple labelled tumors |
| JP7273421B2 (ja) | 2018-02-21 | 2023-05-15 | ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム | ナチュラルキラー細胞の活性化および拡大のための方法ならびにその使用 |
| TW202000229A (zh) | 2018-02-23 | 2020-01-01 | 美商安德賽特公司 | Car t細胞療法之順序方法 |
| EP3693380A1 (en) * | 2019-02-11 | 2020-08-12 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Dual inhibition of plexin-b1 and plexin-b2 |
| MX2021011799A (es) * | 2019-03-28 | 2021-10-26 | Vaccinex Inc | Antagonistas de semaforina 4d para usarlos en la terapia contra el cancer. |
| BR112021025795A2 (pt) * | 2019-06-21 | 2022-02-01 | H Lee Moffitt Cancer Center And Res Institute Inc A Florida Non Profit Corporation | Terapia de combinação com bloqueio da semaforina-4d (sema4d) e terapia com dc1 |
| CA3152371A1 (en) | 2019-08-01 | 2021-02-04 | Vaccinex, Inc. | Combined inhibition of semaphorin-4d and tgf.beta. and compositions therefor |
| WO2021024020A1 (en) * | 2019-08-06 | 2021-02-11 | Astellas Pharma Inc. | Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer |
| CN111158663B (zh) * | 2019-12-26 | 2021-07-02 | 深圳逻辑汇科技有限公司 | 用于处理程序代码中的变量的引用的方法和系统 |
| EP4100428A4 (en) | 2020-02-04 | 2024-03-06 | Seattle Children's Hospital (DBA Seattle Children's Research Institute) | CHIMERIC ANTI-DINITROPHENOL ANTIGEN RECEPTORS |
| CA3181833A1 (en) * | 2020-06-25 | 2021-12-30 | Vaccinex, Inc. | Use of semaphorin-4d binding molecules for the treatment of rett syndrome |
| WO2022040626A1 (en) * | 2020-08-21 | 2022-02-24 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Combination therapy comprising her-2-dc1 vaccine and a probiotic |
| CN112233123B (zh) * | 2020-09-21 | 2024-05-14 | 广州金域医学检验中心有限公司 | 病理图片中肿瘤间质分类方法、装置、计算机设备及存储介质 |
| CN116635064A (zh) | 2020-12-18 | 2023-08-22 | 世纪治疗股份有限公司 | 具有适应性受体特异性的嵌合抗原受体系统 |
| WO2023012314A1 (en) * | 2021-08-05 | 2023-02-09 | Lifearc | Anti-plexin-b1 antibodies |
| CN117802242A (zh) * | 2024-01-22 | 2024-04-02 | 深圳慕光生物科技有限公司 | 一种利用sema4d基因预测肿瘤免疫逃避风险的方法 |
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| NZ201918A (en) | 1981-09-18 | 1987-04-30 | Genentech Inc | N-terminal methionyl analogues of bovine growth hormone |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US4873192A (en) | 1987-02-17 | 1989-10-10 | The United States Of America As Represented By The Department Of Health And Human Services | Process for site specific mutagenesis without phenotypic selection |
| US5892019A (en) | 1987-07-15 | 1999-04-06 | The United States Of America, As Represented By The Department Of Health And Human Services | Production of a single-gene-encoded immunoglobulin |
| US5070192A (en) | 1988-03-23 | 1991-12-03 | The Johns Hopkins University | Cloned human topoisomerase i: cdna expression, and use for autoantibody detection |
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| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
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| US9708601B2 (en) | 2012-04-26 | 2017-07-18 | Vaccinex, Inc. | Fusion proteins to facilitate selection of cells infected with specific immunoglobulin gene recombinant vaccinia virus |
| US10494440B2 (en) | 2012-05-11 | 2019-12-03 | Vaccinex, Inc. | Use of semaphorin-4D binding molecules to promote neurogenesis following stroke |
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| NZ630881A (en) | 2013-10-10 | 2016-03-31 | Vaccinex Inc | Use of semaphorin-4d binding molecules for treatment of atherosclerosis |
| NZ630892A (en) | 2013-10-21 | 2016-03-31 | Vaccinex Inc | Use of semaphorin-4d binding molecules for treating neurodegenerative disorders |
| EP3445397B1 (en) | 2016-04-22 | 2022-11-09 | Vaccinex, Inc. | Integral membrane protein display on poxvirus extracellular enveloped virions |
| CA3032512C (en) | 2016-08-02 | 2025-05-06 | Vaccinex, Inc. | IMPROVED PROCESSES FOR PRODUCING POLYNUCLEOTIDE LIBRARIES IN VACCINE VIRUS/EUKARYOTIC CELLS |
| WO2018156509A1 (en) | 2017-02-22 | 2018-08-30 | Vaccinex, Inc. | Early detection of glial cell activation in neurodegenerative or neuroinflammatory diseases |
-
2014
- 2014-06-20 SG SG10201902380SA patent/SG10201902380SA/en unknown
- 2014-06-20 CN CN201480047166.7A patent/CN105492016B/zh active Active
- 2014-06-20 ES ES14818498T patent/ES2782834T3/es active Active
- 2014-06-20 NZ NZ631015A patent/NZ631015A/en unknown
- 2014-06-20 KR KR1020167001991A patent/KR102291971B1/ko active Active
- 2014-06-20 MX MX2015017485A patent/MX377858B/es unknown
- 2014-06-20 PT PT148184989T patent/PT3013350T/pt unknown
- 2014-06-20 KR KR1020217025537A patent/KR20210104166A/ko not_active Ceased
- 2014-06-20 US US14/892,099 patent/US9828435B2/en active Active
- 2014-06-20 DK DK14818498.9T patent/DK3013350T3/da active
- 2014-06-20 CA CA3098741A patent/CA3098741A1/en active Pending
- 2014-06-20 SG SG11201510505VA patent/SG11201510505VA/en unknown
- 2014-06-20 WO PCT/US2014/043466 patent/WO2014209802A1/en not_active Ceased
- 2014-06-20 EP EP19209162.7A patent/EP3656392A1/en active Pending
- 2014-06-20 US US14/310,848 patent/US9243068B2/en active Active
- 2014-06-20 EA EA201690080A patent/EA036591B1/ru unknown
- 2014-06-20 PL PL14818498T patent/PL3013350T3/pl unknown
- 2014-06-20 CA CA2916245A patent/CA2916245C/en active Active
- 2014-06-20 EP EP14818498.9A patent/EP3013350B1/en active Active
- 2014-06-20 BR BR112015032690-0A patent/BR112015032690B1/pt active IP Right Grant
- 2014-06-20 AU AU2014302812A patent/AU2014302812B2/en active Active
- 2014-06-20 JP JP2016523819A patent/JP6611709B2/ja active Active
-
2015
- 2015-12-23 IL IL243301A patent/IL243301B/en active IP Right Grant
-
2017
- 2017-08-01 US US15/666,133 patent/US10526414B2/en active Active
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2019
- 2019-04-23 US US16/392,451 patent/US11078295B2/en active Active
- 2019-07-11 JP JP2019129005A patent/JP7021153B2/ja active Active
- 2019-07-26 AU AU2019208274A patent/AU2019208274A1/en not_active Abandoned
-
2021
- 2021-06-29 US US17/362,020 patent/US12070500B2/en active Active
-
2022
- 2022-02-03 JP JP2022015562A patent/JP7356531B2/ja active Active
-
2024
- 2024-07-18 US US18/777,075 patent/US20250032609A1/en active Pending
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