JP2016528195A5 - - Google Patents
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- JP2016528195A5 JP2016528195A5 JP2016523819A JP2016523819A JP2016528195A5 JP 2016528195 A5 JP2016528195 A5 JP 2016528195A5 JP 2016523819 A JP2016523819 A JP 2016523819A JP 2016523819 A JP2016523819 A JP 2016523819A JP 2016528195 A5 JP2016528195 A5 JP 2016528195A5
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- Japan
- Prior art keywords
- cancer
- pharmaceutical composition
- antibody
- cells
- antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361839170P | 2013-06-25 | 2013-06-25 | |
| US61/839,170 | 2013-06-25 | ||
| US201361874241P | 2013-09-05 | 2013-09-05 | |
| US61/874,241 | 2013-09-05 | ||
| US201361884771P | 2013-09-30 | 2013-09-30 | |
| US61/884,771 | 2013-09-30 | ||
| US201361907845P | 2013-11-22 | 2013-11-22 | |
| US61/907,845 | 2013-11-22 | ||
| PCT/US2014/043466 WO2014209802A1 (en) | 2013-06-25 | 2014-06-20 | Use of semaphorin-4d inhibitory molecules in combination with an immune modulating therapy to inhibit tumor growth and metastases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019129005A Division JP7021153B2 (ja) | 2013-06-25 | 2019-07-11 | 腫瘍成長および転移を阻害するための免疫調節療法との組み合わせでのセマフォリン－４ｄ阻害分子の使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016528195A JP2016528195A (ja) | 2016-09-15 |
| JP2016528195A5 true JP2016528195A5 (enExample) | 2017-07-27 |
| JP6611709B2 JP6611709B2 (ja) | 2019-11-27 |
Family
ID=52142579
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016523819A Active JP6611709B2 (ja) | 2013-06-25 | 2014-06-20 | 腫瘍成長および転移を阻害するための免疫調節療法との組み合わせでのセマフォリン−４ｄ阻害分子の使用 |
| JP2019129005A Active JP7021153B2 (ja) | 2013-06-25 | 2019-07-11 | 腫瘍成長および転移を阻害するための免疫調節療法との組み合わせでのセマフォリン－４ｄ阻害分子の使用 |
| JP2022015562A Active JP7356531B2 (ja) | 2013-06-25 | 2022-02-03 | 腫瘍成長および転移を阻害するための免疫調節療法との組み合わせでのセマフォリン－４ｄ阻害分子の使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019129005A Active JP7021153B2 (ja) | 2013-06-25 | 2019-07-11 | 腫瘍成長および転移を阻害するための免疫調節療法との組み合わせでのセマフォリン－４ｄ阻害分子の使用 |
| JP2022015562A Active JP7356531B2 (ja) | 2013-06-25 | 2022-02-03 | 腫瘍成長および転移を阻害するための免疫調節療法との組み合わせでのセマフォリン－４ｄ阻害分子の使用 |
Country Status (18)
| Country | Link |
|---|---|
| US (6) | US9243068B2 (enExample) |
| EP (2) | EP3656392A1 (enExample) |
| JP (3) | JP6611709B2 (enExample) |
| KR (2) | KR102291971B1 (enExample) |
| CN (1) | CN105492016B (enExample) |
| AU (2) | AU2014302812B2 (enExample) |
| BR (1) | BR112015032690B1 (enExample) |
| CA (2) | CA3098741C (enExample) |
| DK (1) | DK3013350T3 (enExample) |
| EA (1) | EA036591B1 (enExample) |
| ES (1) | ES2782834T3 (enExample) |
| IL (1) | IL243301B (enExample) |
| MX (1) | MX377858B (enExample) |
| NZ (1) | NZ631015A (enExample) |
| PL (1) | PL3013350T3 (enExample) |
| PT (1) | PT3013350T (enExample) |
| SG (2) | SG10201902380SA (enExample) |
| WO (1) | WO2014209802A1 (enExample) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2427212B1 (en) | 2009-05-08 | 2017-08-23 | Vaccinex, Inc. | Anti-cd100 antibodies and methods for using the same |
| EA029023B1 (ru) | 2011-10-11 | 2018-01-31 | Вэксинекс, Инк. | Применение молекул, связывающих семафорин-4d, для модуляции проницаемости гематоэнцефалического барьера |
| US9090709B2 (en) | 2012-03-28 | 2015-07-28 | Vaccinex, Inc. | Anti-SEMA4D antibodies and epitopes |
| US9708601B2 (en) | 2012-04-26 | 2017-07-18 | Vaccinex, Inc. | Fusion proteins to facilitate selection of cells infected with specific immunoglobulin gene recombinant vaccinia virus |
| US10494440B2 (en) | 2012-05-11 | 2019-12-03 | Vaccinex, Inc. | Use of semaphorin-4D binding molecules to promote neurogenesis following stroke |
| EP2934532B1 (en) | 2012-12-20 | 2019-10-23 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| US9243068B2 (en) | 2013-06-25 | 2016-01-26 | Vaccinex, Inc. | Combination of SEMA-4D inhibitors and immunomodulators to inhibit tumors and metastases |
| NZ630881A (en) | 2013-10-10 | 2016-03-31 | Vaccinex Inc | Use of semaphorin-4d binding molecules for treatment of atherosclerosis |
| NZ630892A (en) | 2013-10-21 | 2016-03-31 | Vaccinex Inc | Use of semaphorin-4d binding molecules for treating neurodegenerative disorders |
| US10278984B2 (en) * | 2014-05-02 | 2019-05-07 | Nitor Therapeutics | Guanosine as an immune potentiator mediated through toll receptors |
| WO2017132541A1 (en) * | 2016-01-27 | 2017-08-03 | University Of Maryland, Baltimore | A method for monitoring cancer and for regulation of semaphorin 4d to improve cancer immunotherapy regimens |
| EP3213768A1 (en) | 2016-03-01 | 2017-09-06 | LODOCO CLINICAL Kft | Combination of low dose immune checkpoint blockade with high dose il-2 for treating metastatic cancer |
| CA3019835A1 (en) | 2016-04-08 | 2017-10-12 | Purdue Research Foundation | Methods and compositions for car t cell therapy |
| WO2017182706A1 (en) * | 2016-04-18 | 2017-10-26 | Faron Pharmaceuticals Oy | Diagnosis of immune_activation using clever-1, tnf-alpha and hla-dr binding agents |
| PT3445397T (pt) | 2016-04-22 | 2023-01-13 | Vaccinex Inc | Exibição de proteína integral de membrana sobre viriões envelopados extracelulares de poxvírus |
| US11975040B2 (en) | 2016-06-16 | 2024-05-07 | The University Of Tokyo | Plexin binding regulator |
| SG11201900595YA (en) | 2016-08-02 | 2019-02-27 | Vaccinex Inc | Improved methods for producing polynucleotide libraries in vaccinia virus/eukaryotic cells |
| USD889258S1 (en) * | 2016-08-04 | 2020-07-07 | Carolin McKie | Beverage container identification marker kit |
| AU2017326003A1 (en) * | 2016-09-16 | 2019-04-11 | Children's Medical Center Corporation | KLRG1 depletion therapy |
| WO2018071668A1 (en) | 2016-10-12 | 2018-04-19 | Board Of Regents, The University Of Texas System | Methods and compositions for tusc2 immunotherapy |
| AU2018219226B2 (en) | 2017-02-07 | 2024-12-19 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents |
| CN110582288B (zh) | 2017-02-28 | 2024-09-20 | 恩多塞特公司 | 用于car t细胞疗法的组合物和方法 |
| SG11201906404RA (en) * | 2017-03-20 | 2019-08-27 | Vaccinex Inc | Treatment of cancer with a semaphorin-4d antibody in combination with an epigenetic modulating agent |
| JP2020517259A (ja) | 2017-04-19 | 2020-06-18 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | 操作された抗原受容体を発現する免疫細胞 |
| JP7246320B2 (ja) | 2017-05-05 | 2023-03-27 | バクシネックス インコーポレーティッド | ヒト抗セマフォリン４ｄ抗体 |
| WO2019144095A1 (en) | 2018-01-22 | 2019-07-25 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Methods of use for car t cells |
| AU2019218729B2 (en) | 2018-02-06 | 2025-12-04 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Fluorescein-specific CARs exhibiting optimal T cell function against FL-PLE labelled tumors |
| WO2019165121A1 (en) | 2018-02-21 | 2019-08-29 | Board Of Regents, The University Of Texas System | Methods for activation and expansion of natural killer cells and uses therof |
| JP7568224B2 (ja) | 2018-02-23 | 2024-10-16 | エンドサイト・インコーポレイテッド | Ｃａｒ ｔ細胞療法のための配列決定法 |
| EP3693380A1 (en) * | 2019-02-11 | 2020-08-12 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Dual inhibition of plexin-b1 and plexin-b2 |
| IL321254A (en) * | 2019-03-28 | 2025-08-01 | Vaccinex Inc | Semaphorin-4D antagonists for use in cancer treatment |
| KR20220044490A (ko) | 2019-06-21 | 2022-04-08 | 백시넥스 인코포레이티드 | 세마포린-4d 차단(sema4d) 및 dc1 요법을 사용한 조합 요법 |
| CA3152371A1 (en) | 2019-08-01 | 2021-02-04 | Vaccinex, Inc. | Combined inhibition of semaphorin-4d and tgf.beta. and compositions therefor |
| WO2021024020A1 (en) * | 2019-08-06 | 2021-02-11 | Astellas Pharma Inc. | Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer |
| CN111158663B (zh) * | 2019-12-26 | 2021-07-02 | 深圳逻辑汇科技有限公司 | 用于处理程序代码中的变量的引用的方法和系统 |
| IL295063A (en) | 2020-02-04 | 2022-09-01 | Seattle Childrens Hospital Dba Seattle Childrens Res Inst | Chimeric antigen receptors (car) against dinitrophenol |
| US11597765B2 (en) | 2020-06-25 | 2023-03-07 | Vaccinex, Inc. | Use of semaphorin-4D binding molecules for the treatment of Rett syndrome |
| US20240009232A1 (en) * | 2020-08-21 | 2024-01-11 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Combination therapy comprising her-2-dc1 vaccine and a probiotic |
| CN112233123B (zh) * | 2020-09-21 | 2024-05-14 | 广州金域医学检验中心有限公司 | 病理图片中肿瘤间质分类方法、装置、计算机设备及存储介质 |
| TW202241935A (zh) | 2020-12-18 | 2022-11-01 | 美商世紀治療股份有限公司 | 具有可調適受體專一性之嵌合抗原受體系統 |
| WO2023012314A1 (en) * | 2021-08-05 | 2023-02-09 | Lifearc | Anti-plexin-b1 antibodies |
| CN117802242A (zh) * | 2024-01-22 | 2024-04-02 | 深圳慕光生物科技有限公司 | 一种利用sema4d基因预测肿瘤免疫逃避风险的方法 |
| WO2026080818A1 (en) * | 2024-10-10 | 2026-04-16 | Vaccinex, Inc. | Use of anti-semaphorin-4d inhibitory molecules in combination with flt3 ligand to inhibit tumor growth and metastasis |
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| NZ201918A (en) | 1981-09-18 | 1987-04-30 | Genentech Inc | N-terminal methionyl analogues of bovine growth hormone |
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| US5892019A (en) | 1987-07-15 | 1999-04-06 | The United States Of America, As Represented By The Department Of Health And Human Services | Production of a single-gene-encoded immunoglobulin |
| US5070192A (en) | 1988-03-23 | 1991-12-03 | The Johns Hopkins University | Cloned human topoisomerase i: cdna expression, and use for autoantibody detection |
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| US9243068B2 (en) | 2013-06-25 | 2016-01-26 | Vaccinex, Inc. | Combination of SEMA-4D inhibitors and immunomodulators to inhibit tumors and metastases |
| NZ630881A (en) | 2013-10-10 | 2016-03-31 | Vaccinex Inc | Use of semaphorin-4d binding molecules for treatment of atherosclerosis |
| NZ630892A (en) | 2013-10-21 | 2016-03-31 | Vaccinex Inc | Use of semaphorin-4d binding molecules for treating neurodegenerative disorders |
| PT3445397T (pt) | 2016-04-22 | 2023-01-13 | Vaccinex Inc | Exibição de proteína integral de membrana sobre viriões envelopados extracelulares de poxvírus |
| SG11201900595YA (en) | 2016-08-02 | 2019-02-27 | Vaccinex Inc | Improved methods for producing polynucleotide libraries in vaccinia virus/eukaryotic cells |
| KR102533921B1 (ko) | 2017-02-22 | 2023-05-17 | 백시넥스 인코포레이티드 | 신경변성 또는 신경염증성 질환에서의 신경교세포 활성화의 조기 검출 |
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2014
- 2014-06-20 US US14/310,848 patent/US9243068B2/en active Active
- 2014-06-20 WO PCT/US2014/043466 patent/WO2014209802A1/en not_active Ceased
- 2014-06-20 AU AU2014302812A patent/AU2014302812B2/en active Active
- 2014-06-20 SG SG10201902380SA patent/SG10201902380SA/en unknown
- 2014-06-20 SG SG11201510505VA patent/SG11201510505VA/en unknown
- 2014-06-20 CA CA3098741A patent/CA3098741C/en active Active
- 2014-06-20 JP JP2016523819A patent/JP6611709B2/ja active Active
- 2014-06-20 ES ES14818498T patent/ES2782834T3/es active Active
- 2014-06-20 CA CA2916245A patent/CA2916245C/en active Active
- 2014-06-20 EP EP19209162.7A patent/EP3656392A1/en active Pending
- 2014-06-20 KR KR1020167001991A patent/KR102291971B1/ko active Active
- 2014-06-20 PL PL14818498T patent/PL3013350T3/pl unknown
- 2014-06-20 EA EA201690080A patent/EA036591B1/ru unknown
- 2014-06-20 BR BR112015032690-0A patent/BR112015032690B1/pt active IP Right Grant
- 2014-06-20 US US14/892,099 patent/US9828435B2/en active Active
- 2014-06-20 CN CN201480047166.7A patent/CN105492016B/zh active Active
- 2014-06-20 PT PT148184989T patent/PT3013350T/pt unknown
- 2014-06-20 DK DK14818498.9T patent/DK3013350T3/da active
- 2014-06-20 NZ NZ631015A patent/NZ631015A/en unknown
- 2014-06-20 MX MX2015017485A patent/MX377858B/es unknown
- 2014-06-20 EP EP14818498.9A patent/EP3013350B1/en active Active
- 2014-06-20 KR KR1020217025537A patent/KR20210104166A/ko not_active Ceased
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2015
- 2015-12-23 IL IL243301A patent/IL243301B/en active IP Right Grant
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2017
- 2017-08-01 US US15/666,133 patent/US10526414B2/en active Active
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2019
- 2019-04-23 US US16/392,451 patent/US11078295B2/en active Active
- 2019-07-11 JP JP2019129005A patent/JP7021153B2/ja active Active
- 2019-07-26 AU AU2019208274A patent/AU2019208274A1/en not_active Abandoned
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2021
- 2021-06-29 US US17/362,020 patent/US12070500B2/en active Active
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2022
- 2022-02-03 JP JP2022015562A patent/JP7356531B2/ja active Active
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2024
- 2024-07-18 US US18/777,075 patent/US20250032609A1/en active Pending
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