JP2024037841A5 - - Google Patents

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JP2024037841A5
JP2024037841A5 JP2023208705A JP2023208705A JP2024037841A5 JP 2024037841 A5 JP2024037841 A5 JP 2024037841A5 JP 2023208705 A JP2023208705 A JP 2023208705A JP 2023208705 A JP2023208705 A JP 2023208705A JP 2024037841 A5 JP2024037841 A5 JP 2024037841A5
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JP
Japan
Prior art keywords
modified oligonucleotide
antisense strand
sirna
nucleotides
counting
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Pending
Application number
JP2023208705A
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English (en)
Japanese (ja)
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JP2024037841A (ja
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Priority claimed from JP2020196720A external-priority patent/JP2021059542A/ja
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Publication of JP2024037841A publication Critical patent/JP2024037841A/ja
Publication of JP2024037841A5 publication Critical patent/JP2024037841A5/ja
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JP2023208705A 2014-12-18 2023-12-11 Ｒｅｖｅｒｓｉｒ（商標）化合物 Pending JP2024037841A (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201462093906P 2014-12-18 2014-12-18
US62/093,906 2014-12-18
US201562238467P 2015-10-07 2015-10-07
US62/238,467 2015-10-07
JP2020196720A JP2021059542A (ja) 2014-12-18 2020-11-27 Ｒｅｖｅｒｓｉｒ（商標）化合物
JP2022186454A JP2023018065A (ja) 2014-12-18 2022-11-22 Ｒｅｖｅｒｓｉｒ（商標）化合物

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2022186454A Division JP2023018065A (ja) 2014-12-18 2022-11-22 Ｒｅｖｅｒｓｉｒ（商標）化合物

Publications (2)

Publication Number Publication Date
JP2024037841A JP2024037841A (ja) 2024-03-19
JP2024037841A5 true JP2024037841A5 (enExample) 2024-10-11

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ID=56127628

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2017532689A Withdrawn JP2018504380A (ja) 2014-12-18 2015-12-17 Ｒｅｖｅｒｓｉｒ（商標）化合物
JP2020196720A Pending JP2021059542A (ja) 2014-12-18 2020-11-27 Ｒｅｖｅｒｓｉｒ（商標）化合物
JP2022186454A Pending JP2023018065A (ja) 2014-12-18 2022-11-22 Ｒｅｖｅｒｓｉｒ（商標）化合物
JP2023208705A Pending JP2024037841A (ja) 2014-12-18 2023-12-11 Ｒｅｖｅｒｓｉｒ（商標）化合物

Family Applications Before (3)

Application Number Title Priority Date Filing Date
JP2017532689A Withdrawn JP2018504380A (ja) 2014-12-18 2015-12-17 Ｒｅｖｅｒｓｉｒ（商標）化合物
JP2020196720A Pending JP2021059542A (ja) 2014-12-18 2020-11-27 Ｒｅｖｅｒｓｉｒ（商標）化合物
JP2022186454A Pending JP2023018065A (ja) 2014-12-18 2022-11-22 Ｒｅｖｅｒｓｉｒ（商標）化合物

Country Status (6)

Country Link
US (3) US20170369872A1 (enExample)
EP (1) EP3234141A4 (enExample)
JP (4) JP2018504380A (enExample)
AU (2) AU2015364508A1 (enExample)
CA (1) CA2970795A1 (enExample)
WO (1) WO2016100716A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016100716A1 (en) 2014-12-18 2016-06-23 Vasant Jadhav Reversirtm compounds
KR20240035907A (ko) * 2016-11-23 2024-03-18 알닐람 파마슈티칼스 인코포레이티드 표적외 효과가 감소된 변형 rna 작용제
WO2019036612A1 (en) * 2017-08-17 2019-02-21 Alnylam Pharmaceuticals, Inc. ADJUSTABLE REVERSIR TM COMPOUNDS
EP3790557A4 (en) 2018-05-07 2022-03-02 Alnylam Pharmaceuticals Inc. COMPOSITIONS AND METHODS FOR ENHANCING STRAND DISTORTION
SG11202010910QA (en) 2018-05-07 2020-12-30 Alnylam Pharmaceuticals Inc Extrahepatic delivery
AU2020415455A1 (en) * 2019-12-23 2022-07-14 University Of Massachusetts Oligonucleotides for tissue specific gene expression modulation
WO2024039776A2 (en) 2022-08-18 2024-02-22 Alnylam Pharmaceuticals, Inc. Universal non-targeting sirna compositions and methods of use thereof
KR20250144467A (ko) 2023-02-09 2025-10-10 알닐람 파마슈티칼스 인코포레이티드 Reversir 분자 및 이의 사용 방법

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