ATE153856T1 - Zusammensetzung zur stimulierung des immunsystems - Google Patents

Zusammensetzung zur stimulierung des immunsystems

Info

Publication number
ATE153856T1
ATE153856T1 AT90914341T AT90914341T ATE153856T1 AT E153856 T1 ATE153856 T1 AT E153856T1 AT 90914341 T AT90914341 T AT 90914341T AT 90914341 T AT90914341 T AT 90914341T AT E153856 T1 ATE153856 T1 AT E153856T1
Authority
AT
Austria
Prior art keywords
immune system
stimulating
composition
chemotherapy
treatment
Prior art date
Application number
AT90914341T
Other languages
English (en)
Inventor
Spiros Jamas
D Davidson Easson Jr
Gary R Ostroff
Original Assignee
Alpha Beta Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alpha Beta Technology filed Critical Alpha Beta Technology
Application granted granted Critical
Publication of ATE153856T1 publication Critical patent/ATE153856T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
AT90914341T 1989-09-08 1990-09-05 Zusammensetzung zur stimulierung des immunsystems ATE153856T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40476589A 1989-09-08 1989-09-08

Publications (1)

Publication Number Publication Date
ATE153856T1 true ATE153856T1 (de) 1997-06-15

Family

ID=23600941

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90914341T ATE153856T1 (de) 1989-09-08 1990-09-05 Zusammensetzung zur stimulierung des immunsystems

Country Status (9)

Country Link
US (1) US5504079A (de)
EP (1) EP0491829B1 (de)
JP (1) JPH05502018A (de)
AT (1) ATE153856T1 (de)
AU (1) AU647751B2 (de)
CA (1) CA2067159A1 (de)
DE (1) DE69030880T2 (de)
ES (1) ES2103276T3 (de)
WO (1) WO1991003248A2 (de)

Families Citing this family (106)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05503952A (ja) * 1989-09-08 1993-06-24 アルファ　ベータ　テクノロジー，インコーポレイティッド 可溶性グルカン類の製造方法
US5811542A (en) * 1989-09-08 1998-09-22 Alpha-Beta Technology, Inc. Method for producing soluble glucans
US5622939A (en) * 1992-08-21 1997-04-22 Alpha-Beta Technology, Inc. Glucan preparation
US5488040A (en) * 1989-09-08 1996-01-30 Alpha-Beta Technology, Inc. Use of neutral soluble glucan preparations to stimulate platelet production
EP0640348A1 (de) * 1993-07-26 1995-03-01 Akzo Nobel N.V. Adjuvansmischung auf Ölbasis und auf Wasserbasis
ZA945587B (en) * 1993-07-28 1995-05-15 Diatech Inc Radiolabeled glucans.
NO300692B1 (no) * 1994-04-29 1997-07-07 Biotec Mackzymal As Solubilisert forgrenet ß-1,3-glukan og anvendelse derav samt anvendelse av usolubilisert forgrenet ß-1,3-glukan
US5622940A (en) * 1994-07-14 1997-04-22 Alpha-Beta Technology Inhibition of infection-stimulated oral tissue destruction by β(1,3)-glucan
US6117850A (en) * 1995-08-28 2000-09-12 The Collaborative Group, Ltd. Mobilization of peripheral blood precursor cells by β(1,3)-glucan
US5786343A (en) * 1997-03-05 1998-07-28 Immudyne, Inc. Phagocytosis activator compositions and their use
GB2325233B (en) * 1997-05-16 2001-07-18 Norsk Hydro As Substrates having bound polysaccharides and bacterial nucleic acids
US6046323A (en) * 1997-07-29 2000-04-04 The Collaborative Group, Ltd. Conformations of PPG-glucan
AU6261999A (en) 1998-09-25 2000-04-17 Collaborative Group, Ltd., The Very high molecular weight beta-glucans
US6369216B1 (en) 1998-09-25 2002-04-09 Biopolymer Engineering Pharmaceutical, Inc. Very high molecular weight β-glucans
US6713459B1 (en) * 2000-04-28 2004-03-30 East Tennessee State University Methods for the prophylactic and therapeutic treatment of cardiac tissue damage
US7011845B2 (en) * 2000-05-09 2006-03-14 Mcp Hahnemann University β-glucans encapsulated in liposomes
US7906492B2 (en) 2001-01-16 2011-03-15 Sloan-Kettering Institute For Cancer Research Therapy-enhancing glucan
US7507724B2 (en) 2001-01-16 2009-03-24 Sloan-Kettering Institute For Cancer Research Therapy-enhancing glucan
US20020123127A1 (en) * 2001-03-01 2002-09-05 Cheung Ling Y. Methods and compositions for reducing odor
US20020123129A1 (en) * 2001-03-01 2002-09-05 Cheung Ling Y. Methods and compositions for degrading nitrogen-containing compounds
US20020123130A1 (en) * 2001-03-01 2002-09-05 Cheung Ling Y. Methods and compositions for degrading polymeric compounds
US6939864B1 (en) 2001-07-09 2005-09-06 Purdue Research Foundation Animal feed compositions and methods of using the same
NO20014256D0 (no) * 2001-09-03 2001-09-03 Bjoern Kristiansen Fremstilling av immunstimulerende forbindelse
US7786094B2 (en) * 2001-10-09 2010-08-31 Biopolymer Engineering, Inc. Use of beta-glucans against biological warfare weapons and pathogens including anthrax
JPWO2003039567A1 (ja) * 2001-11-06 2005-02-24 株式会社オリエントキャンサーセラピー 抗癌組成物
US20040001859A1 (en) * 2002-06-28 2004-01-01 Cheung Ling Yuk Anti-aging dietary supplements
US20040005336A1 (en) * 2002-06-28 2004-01-08 Cheung Ling Yuk Dietary supplements for regulating the central nervous system
US20040001857A1 (en) * 2002-06-28 2004-01-01 Cheung Ling Yuk Dietary supplements for treating hypertension
US20040005335A1 (en) * 2002-06-28 2004-01-08 Cheung Ling Yuk Oral compositions for HIV-infected subjects
US7256026B2 (en) * 2002-06-28 2007-08-14 Ultra Biotech Limited Oral compositions for white blood cell activation and proliferation
AU2003258181A1 (en) 2002-08-13 2004-02-25 University Of Louisville Research Foundation Inc. Methods of using beta glucan as a radioprotective agent
US20070042930A1 (en) * 2002-08-13 2007-02-22 Ross Gordon D Effect of beta-glucan on stem cell recruitment and tissue repair
JP2006502167A (ja) 2002-09-04 2006-01-19 バイオポリマー エンジニアリング，インコーポレイテッド 全グルカン粒子および抗体を用いた癌治療
US20060165700A1 (en) * 2002-09-04 2006-07-27 Ostroff Gary R Cancer therapy using whole glucan particles and antibodies
JP2007524354A (ja) * 2003-01-29 2007-08-30 イミュダイン インコーポレーティッド 動物用の免疫増強剤
US7223400B2 (en) * 2003-06-11 2007-05-29 Ultra Biotech Limited Method to prepare compositions comprising yeast treated with electromagnetic energy
US7226600B2 (en) * 2003-06-11 2007-06-05 Ultra Biotech Limited Method to prepare compositions comprising yeast treated with electromagnetic energy
US7223401B2 (en) * 2003-06-11 2007-05-29 Ultra Biotech Limited Method to prepare compositions comprising yeast treated with electromagnetic energy
US6989253B2 (en) * 2003-06-11 2006-01-24 Ultra Biotech Limited Biological compositions and methods for treatment of testicular cancer
US7223402B2 (en) * 2003-06-11 2007-05-29 Ultra Biotech Limited Method to prepare compositions comprising yeast treated with electromagnetic energy
US6984507B2 (en) * 2003-06-11 2006-01-10 Ultra Biotech Limited Biological compositions and methods for treatment of lung cancer
US7223405B2 (en) * 2003-06-11 2007-05-29 Ultra Biotech Limited Method to prepareompositions comprising yeast treated with electromagnetic energy
US7204987B2 (en) * 2003-06-11 2007-04-17 Ultra Biotech Limited Biological compositions and methods for treatment of prostate cancer
US7214377B2 (en) * 2003-06-11 2007-05-08 Ultra Biotech Limited Method to prepare compositions comprising yeast treated with electromagnetic energy
US7201906B2 (en) * 2003-06-11 2007-04-10 Ultra Biotech Limited Method to prepare compositions comprising yeast treated with electromagnetic energy
US6984508B2 (en) 2003-06-11 2006-01-10 Ultra Biotech Limited Biological compositions and methods for treatment of cervical cancer
US7223403B2 (en) * 2003-06-11 2007-05-29 Ultra Biotech Limited Method to prepare compositions comprising yeast treated with electromagnetic energy
US7204986B2 (en) * 2003-06-11 2007-04-17 Ultra Biotech Limited Method to prepare compositions comprising yeast treated with electromagnetic energy
US7220416B2 (en) * 2003-06-11 2007-05-22 Ultra Biotech Limited Method to prepare compositions comprising yeast treated with electromagnetic energy
US6987012B2 (en) * 2003-06-11 2006-01-17 Ultra Biotech Limited Biological compositions and methods for treatment of colorectal cancer
US7208158B2 (en) 2003-06-11 2007-04-24 Ultra Biotech Limited Method to prepare compositions comprising yeast treated with electromagnetic energy
US7204988B2 (en) * 2003-06-11 2007-04-17 Ultra Biotech Limited Method to prepare compositions comprising yeast treated with electromagnetic energy
US7223404B2 (en) 2003-06-11 2007-05-29 Ultra Biotech Limited Method to prepare compositions comprising yeast treated with electromagnetic energy
US20040265990A1 (en) * 2003-06-30 2004-12-30 Cheung Ling Yuk Biological compositions for reduction of E. coli infections
EP1684777A2 (de) * 2003-08-13 2006-08-02 University Of Louisville Research Foundation, Inc. Wirkung von beta-glucan auf die stammzellenrekrutierung und gewebereparatur
US7259001B2 (en) * 2003-11-18 2007-08-21 Ultra Biotech Limited Methods and compositions for treating male sexual dysfunction
US6913914B2 (en) 2003-11-18 2005-07-05 Ultra Biotech Limited Methods and compositions for treating hepatitis B
US7078202B2 (en) * 2003-11-18 2006-07-18 Ultra Biotech Limited Methods and compositions for treating vascular dementia
US20050106705A1 (en) * 2003-11-18 2005-05-19 Cheung Ling Y. Methods and compositions for treating hyperlipemia
US6913913B2 (en) 2003-11-18 2005-07-05 Ultra Biotech Limited Methods and compositions for treating renal failure
US7297522B2 (en) * 2003-11-18 2007-11-20 Ultra Biotech Limited Methods and compositions for treating epilepsy
US6979562B2 (en) * 2003-11-18 2005-12-27 Ultra Biotech Limited Methods and compositions for treating gastroparesis
US20050106166A1 (en) * 2003-11-18 2005-05-19 Cheung Ling Y. Methods and compositions for treating liver cirrhosis
US6964864B2 (en) * 2003-11-18 2005-11-15 Ultra Biotech Limited Methods and compositions for treating gastritis
US6977168B2 (en) 2003-11-18 2005-12-20 Ultra Biotech Limited Methods and compositions for treating nephrotic syndrome
US7197521B2 (en) * 2003-11-21 2007-03-27 Intel Corporation Method and system performing concurrently mark-sweep garbage collection invoking garbage collection thread to track and mark live objects in heap block using bit vector
US20050271613A1 (en) * 2004-03-29 2005-12-08 Toshio Suzuki Beta-1, 3-1, 6-D-glucan and its use
WO2006085895A2 (en) * 2004-05-10 2006-08-17 Biopolymer Engineering, Inc. Whole glucan particles in combination with antibiotics, vaccines and viral monoclonal antibodies
US7740861B2 (en) 2004-06-16 2010-06-22 University Of Massachusetts Drug delivery product and methods
US7514085B2 (en) * 2004-07-16 2009-04-07 Medimush A/S Immune modulating compounds from fungi
WO2006032039A2 (en) 2004-09-17 2006-03-23 University Of Massachusetts Compositions and their uses for lysosomal enzyme deficiencies
WO2006121803A1 (en) 2005-05-05 2006-11-16 Sensient Flavors Inc. Production of beta-glucans and mannans
EP1896600A2 (de) 2005-06-15 2008-03-12 Medimush A/S Gegen krebs gerichtete kombinationsbehandlung und kit
WO2006133708A1 (en) * 2005-06-15 2006-12-21 Medimush A/S Bioactive agents produced by submerged cultivation of a basidiomycete cell
AR056499A1 (es) * 2005-09-06 2007-10-10 Serapis Farmaceuticals Ltd Compuestos
EP1948245B1 (de) * 2005-10-24 2011-10-05 University of Massachusetts Zusammensetzungen und ihre verwendungen für die gentherapeutische behandlung von knochenerkrankungen
US8323644B2 (en) 2006-01-17 2012-12-04 Sloan-Kettering Institute For Cancer Research Therapy-enhancing glucan
US20080108114A1 (en) * 2006-06-15 2008-05-08 Cox Donald J Glucan preparations
US20080167268A1 (en) * 2006-09-01 2008-07-10 Jun Yan Particulate beta-glucan compositions for regulating dendritic cells
WO2008027581A1 (en) * 2006-09-01 2008-03-06 University Of Louisville Mcrp antagonists and their uses
WO2008057501A2 (en) * 2006-11-06 2008-05-15 Whitehead Institute Immunomodulating compositions and methods of use thereof
US9457047B2 (en) 2006-11-06 2016-10-04 Whitehead Institute Immunomodulating compositions and methods of use thereof
KR20090009513A (ko) * 2007-07-20 2009-01-23 한국원자력연구원 방사선 조사에 의한 저 분자량의 베타글루칸의 제조 방법및 방사선 조사에 의하여 제조된 저 분자량의 베타글루칸
CN105326852B (zh) * 2007-09-27 2018-11-23 生物高聚物工程公司Dba生物治疗公司 β-葡聚糖用于上呼吸道感染症状和心理健康
EP2222283A2 (de) 2007-10-29 2010-09-01 University of Massachusetts Zur freisetzung von nukleinsäuren (sirna) mit hefe-zellwandproteinen verkapselte mehrlagige nanopatikel
US8815818B2 (en) 2008-07-18 2014-08-26 Rxi Pharmaceuticals Corporation Phagocytic cell delivery of RNAI
US9493774B2 (en) 2009-01-05 2016-11-15 Rxi Pharmaceuticals Corporation Inhibition of PCSK9 through RNAi
WO2011011617A1 (en) 2009-07-22 2011-01-27 Biothera, Inc. Therapeutic compositions and methods
WO2011119871A1 (en) 2010-03-24 2011-09-29 Rxi Phrmaceuticals Corporation Rna interference in ocular indications
EP2550002B1 (de) 2010-03-24 2019-05-08 Phio Pharmaceuticals Corp. Rna-interferenz bei dermalen und fibrotischen erkrankungen
US20110293784A1 (en) 2010-05-28 2011-12-01 Anja Wittke Milk-based nutritional compositions
WO2012024229A1 (en) 2010-08-14 2012-02-23 University Of Massachusetts Yeast cell wall particle for receptor-targeted nanoparticle delivery
KR20160110370A (ko) 2013-12-04 2016-09-21 알엑스아이 파마슈티칼스 코포레이션 화학적으로 변형된 올리고뉴클레오티드를 사용한 상처 치유의 치료 방법
US11279934B2 (en) 2014-04-28 2022-03-22 Phio Pharmaceuticals Corp. Methods for treating cancer using nucleic acids targeting MDM2 or MYCN
CA2947619A1 (en) 2014-05-01 2015-11-05 Rxi Pharmaceuticals Corporation Methods for treatment of disorders in the front of the eye utilizing nucleic acid molecules
ES2877099T3 (es) 2014-07-10 2021-11-16 Hibercell Inc Beta-glucano en combinación con agentes anticáncer que afectan al microambiente tumoral
CN107073294A (zh) 2014-09-05 2017-08-18 阿克赛医药公司 使用靶向tyr或mmp1的核酸治疗老化和皮肤病症的方法
EP3851124A1 (de) 2014-11-06 2021-07-21 Biothera, Inc. Die tumormikroumgebung beeinflussende verfahren und zusammensetzungen mit beta-glucan
CA2970795A1 (en) 2014-12-18 2016-06-23 Alnylam Pharmaceuticals, Inc. Reversir compounds
CA2991598A1 (en) 2015-07-06 2017-01-12 Rxi Pharmaceuticals Corporation Nucleic acid molecules targeting superoxide dismutase 1 (sod1)
US10808247B2 (en) 2015-07-06 2020-10-20 Phio Pharmaceuticals Corp. Methods for treating neurological disorders using a synergistic small molecule and nucleic acids therapeutic approach
US11021707B2 (en) 2015-10-19 2021-06-01 Phio Pharmaceuticals Corp. Reduced size self-delivering nucleic acid compounds targeting long non-coding RNA
WO2018156888A1 (en) 2017-02-24 2018-08-30 Biothera Pharmaceuticals, Inc. Beta glucan immunopharmacodynamics
KR20200072886A (ko) 2018-12-13 2020-06-23 주식회사 글루칸 흑효모 유래 바이오폴리머 생산을 위한 배지 조성물 및 그를 이용한 흑효모 유래 바이오폴리머의 제조방법
WO2021064088A1 (en) * 2019-10-04 2021-04-08 Universiteit Gent Beta-glucans having superior immuno-stimulating properties
US20230002766A1 (en) 2019-11-08 2023-01-05 Phio Pharmaceuticals Corp. Chemically modified oligonucleotides targeting bromodomain containing protein 4 (brd4) for immunotherapy

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5571701A (en) * 1978-11-24 1980-05-30 Sankyo Co Ltd Hydrolyzate polysaccharide, its preparation, and immunoregulator containing hydrolyzate polysaccharide as active ingredient
JPS5676401A (en) * 1979-11-27 1981-06-24 Hitoshi Ito Simple glucan separated from cultured choray, preparation thereof and antitumor agent containing its polysaccharide as effective component
FR2477416A1 (fr) * 1980-03-10 1981-09-11 Unicler Utilisation de hansenula ou d'extraits de hansenula, comme medicament
JPS5945301A (ja) * 1982-09-09 1984-03-14 Toyo Soda Mfg Co Ltd 多糖類及びその製造法
JPS59210901A (ja) * 1983-05-17 1984-11-29 Nippon Kinoko Kenkyusho プロテオグルカン及びそれからなる抗ガン剤
US4810646A (en) * 1984-11-28 1989-03-07 Massachusetts Institute Of Technology Glucan compositions and process for preparation thereof
US4739046A (en) * 1985-08-19 1988-04-19 Luzio Nicholas R Di Soluble phosphorylated glucan

Also Published As

Publication number Publication date
ES2103276T3 (es) 1997-09-16
CA2067159A1 (en) 1991-03-09
DE69030880T2 (de) 1997-09-18
AU6429290A (en) 1991-04-08
EP0491829B1 (de) 1997-06-04
AU647751B2 (en) 1994-03-31
WO1991003248A3 (en) 1991-06-13
DE69030880D1 (de) 1997-07-10
WO1991003248A2 (en) 1991-03-21
US5504079A (en) 1996-04-02
EP0491829A1 (de) 1992-07-01
JPH05502018A (ja) 1993-04-15

Similar Documents

Publication Publication Date Title
ATE153856T1 (de) Zusammensetzung zur stimulierung des immunsystems
KR950701350A (ko) 부작용 감소와 동시에 인터페론을 이용한 질환의 치료방법 및 조성물(methods and compositions for the treatment of diseases with interferon while reducing side effects)
DK0502092T3 (da) Oralt præparat til behandling af inflammatoriske tarmsygdomme
EA200600076A1 (ru) Композиции и способы увеличения активности теломеразы
BR0317064A (pt) Administração de células dentrìticas parcialmente amadurecidas in vitro para o tratamento de tumores
Foldi et al. Effect of complex decongestive physiotherapy on gene expression for the inflammatory response in peripheral lymphedema
HU213677B (en) Pharmaceutical compositions for preventing and treating tumor diseases, and process for producing them
DK0484340T3 (da) Behandling til nedsættelse af ødem ved hjerne- og muskelbeskadigelser
BRPI0409699A (pt) métodos de indução do efeito diurético, de indução, manutenção ou restauração do efeito diurético de diurético não modificador de adenosina, de manutenção, restauração ou melhoria da função renal em paciente, de indução de diurese, de prevenção do inìcio de deficiência renal em paciente com sobrecarga de fluidos ou chf, de tratamento de paciente que sofre de chf e de melhoria dos resultados globais da saúde, composição farmacêutica e seus usos
DE3650505T2 (de) AICA riboside zur prophylaktischen Behandlung von Krankheiten mit einer verminderten Durchblutung.
AP9801286A0 (en) Therapeutic compounds.
MXPA00010254A (es) Tratamiento de disfuncion sexual en ciertos grupos de pacientes.
AU5643299A (en) Humic acid and its use in the treatment of various conditions
HUP9903679A2 (hu) Olanzapin alkalmazása bipoláris zavar kezelésére szolgáló gyógyszerkészítmények előállítására
DK0859630T3 (da) Kombination af termozolomid og alfa-IFN til behandling af fremskreden cancer
PT1150981E (pt) Composto nucleosidico terapeutico
RU2068266C1 (ru) Способ повышения остроты слуха
GR950100316A (el) Φαρμακευτικο παρασκευασμα βασιζομενο σε αιωρημα εμβρυικων κυτταρων με δραση ανοσοποιητικης υποκαταστασης και μεθοδος θεραπειας του συνδρομου της επικτητης μολυνσης ανοσοποιητικης ανεπαρκειας (hiv) με τη χρηση αυτου του παρασκευασματος.
RU94013606A (ru) Гемостимулятор
DK0788355T3 (da) Anvendelse af intravenøst indgiveligt jern til behandling af tumorsygdomme og/eller infektionssygdomme
MD1135F1 (en) Paradontium treatment method
SE9704451D0 (sv) New method and compositions for the treatment of autoimmune diseases
RU94022334A (ru) Способ лечения и профилактики инвазионных заболеваний
TR200000540T2 (tr) Virütik ve mikrobiyal enfeksiyonları ve aşırı zayıflama sendromlarını tedavi etmek için ilaç ulaştırma araçları ve yöntemleri.
MD2164G2 (ro) Metodă de tratament al contuziilor oculare

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties