JP2024028879A5 - - Google Patents
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- JP2024028879A5 JP2024028879A5 JP2023206434A JP2023206434A JP2024028879A5 JP 2024028879 A5 JP2024028879 A5 JP 2024028879A5 JP 2023206434 A JP2023206434 A JP 2023206434A JP 2023206434 A JP2023206434 A JP 2023206434A JP 2024028879 A5 JP2024028879 A5 JP 2024028879A5
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- JP
- Japan
- Prior art keywords
- nucleic acid
- compartments
- acid molecules
- signal
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662423601P | 2016-11-17 | 2016-11-17 | |
| US62/423,601 | 2016-11-17 | ||
| JP2019521723A JP6872182B2 (ja) | 2016-11-17 | 2017-11-16 | 核酸分析および定量化のための方法ならびにシステム |
| JP2021061372A JP7490610B2 (ja) | 2016-11-17 | 2021-03-31 | 核酸分析および定量化のための方法ならびにシステム |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021061372A Division JP7490610B2 (ja) | 2016-11-17 | 2021-03-31 | 核酸分析および定量化のための方法ならびにシステム |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024028879A JP2024028879A (ja) | 2024-03-05 |
| JP2024028879A5 true JP2024028879A5 (https=) | 2024-08-19 |
| JP7709505B2 JP7709505B2 (ja) | 2025-07-16 |
Family
ID=62145777
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019521723A Active JP6872182B2 (ja) | 2016-11-17 | 2017-11-16 | 核酸分析および定量化のための方法ならびにシステム |
| JP2021061372A Active JP7490610B2 (ja) | 2016-11-17 | 2021-03-31 | 核酸分析および定量化のための方法ならびにシステム |
| JP2023206434A Active JP7709505B2 (ja) | 2016-11-17 | 2023-12-06 | 核酸分析および定量化のための方法ならびにシステム |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019521723A Active JP6872182B2 (ja) | 2016-11-17 | 2017-11-16 | 核酸分析および定量化のための方法ならびにシステム |
| JP2021061372A Active JP7490610B2 (ja) | 2016-11-17 | 2021-03-31 | 核酸分析および定量化のための方法ならびにシステム |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US10519494B2 (https=) |
| EP (4) | EP4617381A3 (https=) |
| JP (3) | JP6872182B2 (https=) |
| KR (3) | KR102422907B1 (https=) |
| CN (2) | CN115044655A (https=) |
| AU (3) | AU2017363076B2 (https=) |
| CA (1) | CA3042724A1 (https=) |
| ES (2) | ES2909055T3 (https=) |
| WO (1) | WO2018094091A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11285478B2 (en) | 2016-04-04 | 2022-03-29 | Combinati Incorporated | Microfluidic siphoning array for nucleic acid quantification |
| ES2909055T3 (es) | 2016-11-17 | 2022-05-05 | Combinati Incorporated | Métodos y sistemas para el análisis y la cuantificación de ácidos nucleicos |
| KR20200115552A (ko) | 2018-01-22 | 2020-10-07 | 루미넥스 코포레이션 | 별개의 용융 분석을 위한 방법 및 조성물 |
| CN110835645B (zh) * | 2018-08-16 | 2022-10-21 | 思纳福(北京)医疗科技有限公司 | 数字pcr检测方法 |
| GB201812192D0 (en) | 2018-07-26 | 2018-09-12 | Ttp Plc | Variable temperature reactor, heater and control circuit for the same |
| EP3610947B1 (en) | 2018-08-17 | 2021-04-21 | F. Hoffmann-La Roche AG | Microfluidic system for digital polymerase chain reaction of a biological sample, and respective method |
| AU2019397371B2 (en) | 2018-12-10 | 2025-09-18 | Combinati Incorporated | Microfluidic array for sample digitization |
| CN109920474B (zh) * | 2019-03-14 | 2021-03-02 | 深圳市检验检疫科学研究院 | 绝对定量方法、装置、计算机设备和存储介质 |
| US11408032B2 (en) | 2020-01-17 | 2022-08-09 | Element Biosciences, Inc. | Tube lens design for improved depth-of-field |
| CA3187564A1 (en) * | 2020-06-22 | 2021-12-30 | Combinati Incorporated | Systems and methods for analyzing a biological sample |
| CA3195362A1 (en) | 2020-09-28 | 2022-03-31 | Combinati Incorporated | Devices and methods for sample processing |
| KR20240063107A (ko) | 2021-07-21 | 2024-05-10 | 엘리먼트 바이오사이언스, 인크. | 핵산 시퀀싱을 위한 광학 시스템 및 이의 방법 |
| US20230028814A1 (en) * | 2021-07-26 | 2023-01-26 | Mound Laser & Photonics Center, Inc. | Method for delivering a chemistry to microchambers via a channel |
| EP4388132A1 (en) | 2021-08-19 | 2024-06-26 | Luminex Corporation | Digital amplification assay analysis method |
| US20240375102A1 (en) | 2021-09-14 | 2024-11-14 | Combinati Incorporated | Microfluidic device and method for processing biological samples |
| KR20230067718A (ko) * | 2021-11-08 | 2023-05-17 | 삼성전자주식회사 | 유전자 증폭 장치 및 방법 |
| WO2023108014A1 (en) | 2021-12-07 | 2023-06-15 | Luminex Corporation | Methods and compositions for nucleic acid analysis |
Family Cites Families (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| EP0991777A1 (en) | 1997-06-18 | 2000-04-12 | Ulrich J. Krull | Nucleic acid biosensor diagnostics |
| US6977145B2 (en) | 1999-07-28 | 2005-12-20 | Serono Genetics Institute S.A. | Method for carrying out a biochemical protocol in continuous flow in a microreactor |
| US6569674B1 (en) | 1999-12-15 | 2003-05-27 | Amersham Biosciences Ab | Method and apparatus for performing biological reactions on a substrate surface |
| US6875619B2 (en) | 1999-11-12 | 2005-04-05 | Motorola, Inc. | Microfluidic devices comprising biochannels |
| US6361958B1 (en) | 1999-11-12 | 2002-03-26 | Motorola, Inc. | Biochannel assay for hybridization with biomaterial |
| AU2082701A (en) | 1999-12-09 | 2001-06-18 | Motorola, Inc. | Multilayered microfluidic devices for analyte reactions |
| US20050009101A1 (en) | 2001-05-17 | 2005-01-13 | Motorola, Inc. | Microfluidic devices comprising biochannels |
| US6848462B2 (en) | 2001-12-06 | 2005-02-01 | Nanostream, Inc. | Adhesiveless microfluidic device fabrication |
| AU2003299541A1 (en) | 2002-10-02 | 2004-05-25 | California Institute Of Technology | Microfluidic nucleic acid analysis |
| US7169602B2 (en) | 2002-12-04 | 2007-01-30 | Applera Corporation | Sample substrate for use in biological testing and method for filling a sample substrate |
| US20060094108A1 (en) * | 2002-12-20 | 2006-05-04 | Karl Yoder | Thermal cycler for microfluidic array assays |
| WO2005024436A1 (ja) | 2003-09-02 | 2005-03-17 | Nec Corporation | カスタマイズ可能なチップおよびその製造方法 |
| US20050226779A1 (en) * | 2003-09-19 | 2005-10-13 | Oldham Mark F | Vacuum assist for a microplate |
| JP2005329333A (ja) | 2004-05-20 | 2005-12-02 | Japan Science & Technology Agency | マイクロ脱気デバイス |
| US7608160B2 (en) | 2004-10-13 | 2009-10-27 | Rheonix, Inc. | Laminated microfluidic structures and method for making |
| US8715446B2 (en) | 2004-10-13 | 2014-05-06 | Rheonix, Inc. | Latent solvent-based microfluidic apparatus, methods, and applications |
| DE102004063438A1 (de) | 2004-12-23 | 2006-07-06 | Oktavia Backes | Neuartige mikrofluidische Probenträger |
| WO2006116616A2 (en) | 2005-04-26 | 2006-11-02 | Applera Corporation | Systems and methods for multiple analyte detection |
| EP1886145A2 (en) * | 2005-05-03 | 2008-02-13 | Applera Corporation | Fluorescent detection system and dye set for use therewith |
| WO2007011867A2 (en) | 2005-07-15 | 2007-01-25 | Applera Corporation | Fluid processing device and method |
| JP4943445B2 (ja) | 2005-10-26 | 2012-05-30 | ゼネラル・エレクトリック・カンパニイ | 流体試料をセンサーアレイにデリバリーするための方法及びシステム |
| GB2445738A (en) | 2007-01-16 | 2008-07-23 | Lab901 Ltd | Microfluidic device |
| US9550184B2 (en) | 2007-02-05 | 2017-01-24 | Shimadzu Corporation | Reactor plate and reaction processing method |
| EP2816122A1 (en) | 2008-02-15 | 2014-12-24 | Mayo Foundation For Medical Education And Research | Detecting neoplasm from a stool sample |
| WO2009105499A1 (en) | 2008-02-20 | 2009-08-27 | Termaat Joel R | Thermocycler and sample vessel for rapid amplification of dna |
| US9487822B2 (en) * | 2008-03-19 | 2016-11-08 | Fluidigm Corporation | Method and apparatus for determining copy number variation using digital PCR |
| JP2009236555A (ja) | 2008-03-26 | 2009-10-15 | Shimadzu Corp | 流体デバイス及びその製造方法 |
| US20090250347A1 (en) | 2008-04-03 | 2009-10-08 | Protea Biosciences, Inc. | Microfluidic devices & processes for electrokinetic transport |
| KR101829182B1 (ko) * | 2009-04-02 | 2018-03-29 | 플루이다임 코포레이션 | 표적 핵산의 바코딩을 위한 멀티 프라이머 증폭 방법 |
| EP2248915B1 (en) * | 2009-05-05 | 2013-09-18 | Qiagen GmbH | Detection of multiple nucleic acid sequences in a reaction cartridge |
| US9238346B2 (en) | 2009-10-08 | 2016-01-19 | National Research Council Of Canada | Microfluidic device, composition and method of forming |
| ES2930133T3 (es) * | 2010-03-09 | 2022-12-07 | Ande Corp | Biochip con almacenamiento de reactivo |
| US8720036B2 (en) * | 2010-03-09 | 2014-05-13 | Netbio, Inc. | Unitary biochip providing sample-in to results-out processing and methods of manufacture |
| US8376317B2 (en) | 2010-03-29 | 2013-02-19 | Purdue Research Foundation | Microfluidic purge valve |
| EP3236260B1 (en) | 2011-04-13 | 2020-09-30 | Akonni Biosystems, Inc. | Method for making a microarray assembly |
| WO2012162779A1 (en) * | 2011-05-27 | 2012-12-06 | The University Of British Columbia | Microfluidic cell trap and assay apparatus for high-throughput analysis |
| WO2013130910A1 (en) | 2012-02-29 | 2013-09-06 | Integenx Inc. | Sample preparation, processing and analysis systems |
| US9050593B2 (en) * | 2011-11-23 | 2015-06-09 | Wisconsin Alumni Research Foundation | Self-loading microfluidic device and methods of use |
| ES2665252T3 (es) * | 2011-12-30 | 2018-04-25 | Abbott Molecular Inc. | Purificación de ácido nucleico de microorganismos a partir de muestras del hospedador |
| EP2852682B1 (en) | 2012-05-21 | 2017-10-04 | Fluidigm Corporation | Single-particle analysis of particle populations |
| SG10201804101XA (en) * | 2012-09-10 | 2018-07-30 | Biofire Diagnostics Llc | Multiple amplification cycle detection |
| CA2895638A1 (en) * | 2013-03-15 | 2014-09-18 | Fluidigm Corporation | Methods and devices for analysis of defined multicellular combinations |
| DE102013205412A1 (de) | 2013-03-27 | 2014-10-02 | Robert Bosch Gmbh | Normal-geschlossenes Ventil für mikrofluidische Bauteile aus einem polymeren Schichtsystem sowie Verfahren |
| CN105531591B (zh) * | 2013-08-09 | 2018-08-10 | 加利福尼亚大学董事会 | 数字流体样品分离设备和用于一步定量样品分析的方法 |
| WO2015023616A2 (en) * | 2013-08-12 | 2015-02-19 | The Johns Hopkins University | Method for comprehensive, quantitative, and highly sensitive discrimination of nucleic acid sequences in homogeneous and heterogeneous populations |
| JP6427753B2 (ja) * | 2013-09-11 | 2018-11-28 | 国立大学法人大阪大学 | 熱対流生成用チップ、熱対流生成装置、及び熱対流生成方法 |
| EP3077806B1 (en) | 2013-12-06 | 2019-09-11 | Ortho Clinical Diagnostics, Inc. | Assay device having a wash port |
| KR101562318B1 (ko) | 2014-02-10 | 2015-10-22 | 나노바이오시스 주식회사 | 미세유체 칩 및 이를 이용한 실시간 분석 장치 |
| CN106461697B (zh) * | 2014-03-13 | 2019-05-14 | 吉纳帕希斯股份有限公司 | 用于样品制备和分析的微流体装置、系统和方法 |
| CN104946510B (zh) | 2014-03-31 | 2017-06-06 | 博奥生物集团有限公司 | 集核酸扩增和微阵列检测于一体的微流控装置 |
| CN105358673A (zh) * | 2014-05-21 | 2016-02-24 | 卡尤迪生物科技（北京）有限公司 | 用于热循环的系统和方法 |
| WO2016170109A1 (en) * | 2015-04-24 | 2016-10-27 | Roche Diagnostics Gmbh | Digital pcr systems and methods using digital microfluidics |
| CN104877905A (zh) | 2015-05-04 | 2015-09-02 | 清华大学深圳研究生院 | 细胞体外共培养微流控芯片、系统及方法 |
| CN104894106A (zh) | 2015-05-23 | 2015-09-09 | 浙江大学 | 高集成度等距等分核酸扩增微流控芯片及应用 |
| US11285478B2 (en) | 2016-04-04 | 2022-03-29 | Combinati Incorporated | Microfluidic siphoning array for nucleic acid quantification |
| US9845499B2 (en) * | 2016-04-04 | 2017-12-19 | Combinati Incorporated | Microfluidic siphoning array for nucleic acid quantification |
| US11141727B2 (en) * | 2016-07-12 | 2021-10-12 | EMULATE, Inc. | Removing bubbles in a microfluidic device |
| ES2909055T3 (es) | 2016-11-17 | 2022-05-05 | Combinati Incorporated | Métodos y sistemas para el análisis y la cuantificación de ácidos nucleicos |
| EP3346262A1 (en) | 2017-01-10 | 2018-07-11 | Universite d'Aix-Marseille (AMU) | Optical thermal method and system for diagnosing pathologies |
| WO2019108851A1 (en) | 2017-11-30 | 2019-06-06 | 10X Genomics, Inc. | Systems and methods for nucleic acid preparation and analysis |
| PL425106A1 (pl) | 2018-03-30 | 2019-10-07 | Bacteromic Spółka Z Ograniczoną Odpowiedzialnością | Chip mikroprzepływowy |
| EP3774052A4 (en) | 2018-04-04 | 2022-01-05 | Combinati Incorporated | MICROFLUIDIC SUCTION ARRANGEMENT FOR NUCLEIC ACID QUANTIFICATION |
| AU2019397371B2 (en) | 2018-12-10 | 2025-09-18 | Combinati Incorporated | Microfluidic array for sample digitization |
| JP7467061B2 (ja) * | 2019-10-09 | 2024-04-15 | 株式会社ジャパンディスプレイ | 検出装置 |
| KR20230015878A (ko) | 2020-01-24 | 2023-01-31 | 콤비네티 인코포레이티드 | 미세유체 디바이스 제조를 위한 방법 및 시스템 |
| CA3187564A1 (en) | 2020-06-22 | 2021-12-30 | Combinati Incorporated | Systems and methods for analyzing a biological sample |
| WO2022067184A1 (en) | 2020-09-28 | 2022-03-31 | Combinati Incorporated | Devices and methods for sample processing |
| CA3195362A1 (en) | 2020-09-28 | 2022-03-31 | Combinati Incorporated | Devices and methods for sample processing |
-
2017
- 2017-11-16 ES ES17871760T patent/ES2909055T3/es active Active
- 2017-11-16 EP EP25170780.8A patent/EP4617381A3/en active Pending
- 2017-11-16 CN CN202210685818.6A patent/CN115044655A/zh active Pending
- 2017-11-16 ES ES21211332T patent/ES2967462T3/es active Active
- 2017-11-16 EP EP21211332.8A patent/EP3984642B1/en active Active
- 2017-11-16 CA CA3042724A patent/CA3042724A1/en active Pending
- 2017-11-16 KR KR1020217028206A patent/KR102422907B1/ko active Active
- 2017-11-16 EP EP23190271.9A patent/EP4282981A3/en not_active Withdrawn
- 2017-11-16 KR KR1020197015614A patent/KR102300480B1/ko active Active
- 2017-11-16 WO PCT/US2017/062078 patent/WO2018094091A1/en not_active Ceased
- 2017-11-16 AU AU2017363076A patent/AU2017363076B2/en active Active
- 2017-11-16 JP JP2019521723A patent/JP6872182B2/ja active Active
- 2017-11-16 EP EP17871760.9A patent/EP3541519B1/en active Active
- 2017-11-16 CN CN201780083776.6A patent/CN110177621B/zh active Active
- 2017-11-16 KR KR1020227024271A patent/KR102769397B1/ko active Active
-
2019
- 2019-05-09 US US16/408,041 patent/US10519494B2/en active Active
- 2019-10-30 US US16/669,205 patent/US11697844B2/en active Active
-
2021
- 2021-03-31 JP JP2021061372A patent/JP7490610B2/ja active Active
- 2021-07-23 AU AU2021206903A patent/AU2021206903C1/en active Active
-
2022
- 2022-01-19 US US17/578,942 patent/US12091711B2/en active Active
-
2023
- 2023-12-06 JP JP2023206434A patent/JP7709505B2/ja active Active
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2024
- 2024-01-17 AU AU2024200310A patent/AU2024200310B2/en active Active
- 2024-09-06 US US18/827,365 patent/US20250109431A1/en active Pending
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