JP2024010112A5 - - Google Patents
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- JP2024010112A5 JP2024010112A5 JP2023183886A JP2023183886A JP2024010112A5 JP 2024010112 A5 JP2024010112 A5 JP 2024010112A5 JP 2023183886 A JP2023183886 A JP 2023183886A JP 2023183886 A JP2023183886 A JP 2023183886A JP 2024010112 A5 JP2024010112 A5 JP 2024010112A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acids
- ppr
- combination
- constituting
- asparagine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024194918A JP7789426B2 (ja) | 2011-10-21 | 2024-11-07 | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の設計方法及びその利用 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011231346 | 2011-10-21 | ||
| JP2011231346 | 2011-10-21 | ||
| JP2021086108A JP7157483B2 (ja) | 2011-10-21 | 2021-05-21 | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の設計方法及びその利用 |
| JP2022158241A JP7381133B2 (ja) | 2011-10-21 | 2022-09-30 | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の設計方法及びその利用 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022158241A Division JP7381133B2 (ja) | 2011-10-21 | 2022-09-30 | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の設計方法及びその利用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024194918A Division JP7789426B2 (ja) | 2011-10-21 | 2024-11-07 | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の設計方法及びその利用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024010112A JP2024010112A (ja) | 2024-01-23 |
| JP2024010112A5 true JP2024010112A5 (https=) | 2024-07-23 |
| JP7590019B2 JP7590019B2 (ja) | 2024-11-26 |
Family
ID=48141047
Family Applications (9)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013539727A Active JP6164488B2 (ja) | 2011-10-21 | 2012-10-22 | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の設計方法及びその利用 |
| JP2017112765A Active JP6267388B2 (ja) | 2011-10-21 | 2017-06-07 | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の設計方法及びその利用 |
| JP2017112764A Active JP6270192B2 (ja) | 2011-10-21 | 2017-06-07 | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の設計方法及びその利用 |
| JP2017244765A Active JP6454398B2 (ja) | 2011-10-21 | 2017-12-21 | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の設計方法及びその利用 |
| JP2017244766A Active JP6934644B2 (ja) | 2011-10-21 | 2017-12-21 | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の設計方法及びその利用 |
| JP2021086108A Active JP7157483B2 (ja) | 2011-10-21 | 2021-05-21 | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の設計方法及びその利用 |
| JP2022158241A Active JP7381133B2 (ja) | 2011-10-21 | 2022-09-30 | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の設計方法及びその利用 |
| JP2023183886A Active JP7590019B2 (ja) | 2011-10-21 | 2023-10-26 | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の設計方法及びその利用 |
| JP2024194918A Active JP7789426B2 (ja) | 2011-10-21 | 2024-11-07 | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の設計方法及びその利用 |
Family Applications Before (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013539727A Active JP6164488B2 (ja) | 2011-10-21 | 2012-10-22 | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の設計方法及びその利用 |
| JP2017112765A Active JP6267388B2 (ja) | 2011-10-21 | 2017-06-07 | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の設計方法及びその利用 |
| JP2017112764A Active JP6270192B2 (ja) | 2011-10-21 | 2017-06-07 | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の設計方法及びその利用 |
| JP2017244765A Active JP6454398B2 (ja) | 2011-10-21 | 2017-12-21 | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の設計方法及びその利用 |
| JP2017244766A Active JP6934644B2 (ja) | 2011-10-21 | 2017-12-21 | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の設計方法及びその利用 |
| JP2021086108A Active JP7157483B2 (ja) | 2011-10-21 | 2021-05-21 | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の設計方法及びその利用 |
| JP2022158241A Active JP7381133B2 (ja) | 2011-10-21 | 2022-09-30 | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の設計方法及びその利用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024194918A Active JP7789426B2 (ja) | 2011-10-21 | 2024-11-07 | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の設計方法及びその利用 |
Country Status (8)
| Country | Link |
|---|---|
| US (7) | US9513283B2 (https=) |
| EP (2) | EP2784157B1 (https=) |
| JP (9) | JP6164488B2 (https=) |
| AU (5) | AU2012326971C1 (https=) |
| DK (1) | DK2784157T3 (https=) |
| ES (1) | ES2751126T3 (https=) |
| PT (1) | PT2784157T (https=) |
| WO (1) | WO2013058404A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2784157T3 (da) | 2011-10-21 | 2019-10-21 | Univ Kyushu Nat Univ Corp | Designfremgangsmåde til et rna-bindende protein under anvendelse af ppr-motiv og anvendelse deraf |
| AU2013248928A1 (en) * | 2012-04-16 | 2014-12-04 | The State Board Of Higher Education On Behalf Of The University Of Oregon | Peptides for the binding of nucleotide targets |
| AU2014258386B2 (en) | 2013-04-22 | 2018-10-25 | Hiroshima University | DNA binding protein using PPR motif, and use thereof |
| EP3115457B1 (en) | 2014-03-05 | 2019-10-02 | National University Corporation Kobe University | Genomic sequence modification method for specifically converting nucleic acid bases of targeted dna sequence, and molecular complex for use in same |
| ES2938623T3 (es) | 2015-09-09 | 2023-04-13 | Univ Kobe Nat Univ Corp | Método para convertir una secuencia del genoma de una bacteria gram-positiva mediante una conversión específica de una base de ácido nucleico de una secuencia de ADN seleccionada como diana y el complejo molecular utilizado en el mismo |
| CA3005968A1 (en) | 2015-11-23 | 2017-06-01 | The Regents Of The University Of California | Tracking and manipulating cellular rna via nuclear delivery of crispr/cas9 |
| JP6923205B2 (ja) | 2015-11-27 | 2021-08-18 | 国立大学法人神戸大学 | 標的化したｄｎａ配列の核酸塩基を特異的に変換する、単子葉植物のゲノム配列の変換方法、及びそれに用いる分子複合体 |
| AU2017275184B2 (en) * | 2016-06-03 | 2021-05-06 | Kyushu University, National University Corporation | Fusion protein for improving protein expression from target mRNA |
| BR112018075010A2 (pt) * | 2016-06-03 | 2019-03-12 | Kyushu University, National University Corporation | proteína de fusão para melhorar o nível de expressão de proteína a partir de rnam alvo |
| EP3498726A4 (en) * | 2016-08-10 | 2020-03-25 | Fujifilm Wako Pure Chemical Corporation | DNA BINDING PROTEIN USING A PPR PATTERN AND USE OF SAID DNA BINDING PROTEIN |
| WO2018208998A1 (en) | 2017-05-10 | 2018-11-15 | The Regents Of The University Of California | Directed editing of cellular rna via nuclear delivery of crispr/cas9 |
| CN108932400B (zh) * | 2017-05-24 | 2021-07-23 | 北京工业大学 | 一种考虑界面信息的有效的蛋白质-rna复合物结构预测方法 |
| CN108959852B (zh) * | 2017-05-24 | 2021-12-24 | 北京工业大学 | 基于氨基酸-核苷酸成对偏好性信息的蛋白质上与rna结合模块的预测方法 |
| KR20210058806A (ko) | 2018-06-08 | 2021-05-24 | 로카나바이오 인크. | Rna 표적화 융합 단백질 조성물 및 사용 방법 |
| SG11202113057XA (en) * | 2019-05-29 | 2021-12-30 | Editforce Inc | Ppr protein causing less aggregation and use of the same |
| CN114729017A (zh) * | 2019-05-29 | 2022-07-08 | 日商基因编辑力股份有限公司 | Ppr蛋白的有效制作方法及其应用 |
| EP3997227A1 (en) | 2019-07-10 | 2022-05-18 | Locanabio, Inc. | Rna-targeting knockdown and replacement compositions and methods for use |
| WO2021201198A1 (ja) * | 2020-03-31 | 2021-10-07 | エディットフォース株式会社 | 標的ｒｎａを編集する方法 |
| WO2022119974A1 (en) | 2020-12-01 | 2022-06-09 | Locanabio, Inc. | Rna-targeting compositions and methods for treating cag repeat diseases |
| JP2023551874A (ja) | 2020-12-01 | 2023-12-13 | ロックアネイビオ， インコーポレイテッド | 筋強直性ジストロフィー１型を処置するためのｒｎａ標的化組成物および方法 |
| WO2022221278A1 (en) | 2021-04-12 | 2022-10-20 | Locanabio, Inc. | Compositions and methods comprising hybrid promoters |
| WO2022226375A1 (en) | 2021-04-23 | 2022-10-27 | Locanabio, Inc. | Tissue-targeted modified aav capsids and methods of use thereof |
| CA3216419A1 (en) | 2021-04-23 | 2022-10-27 | Greg NACHTRAB | Tissue-targeted modified aav capsids and methods of use thereof |
| CA3216313A1 (en) * | 2021-04-30 | 2022-11-03 | Masayuki NAKAMORI | Myotonic dystrophy type 1 therapeutic drug |
| JP7125727B1 (ja) * | 2021-09-07 | 2022-08-25 | 国立大学法人千葉大学 | 核酸配列改変用組成物および核酸配列の標的部位を改変する方法 |
| US20240296904A1 (en) * | 2021-09-29 | 2024-09-05 | Boe Technology Group Co., Ltd. | Method and apparatus for predicting rna-protein interaction, medium and electronic device |
| JPWO2023120658A1 (https=) * | 2021-12-24 | 2023-06-29 | ||
| WO2023154807A2 (en) | 2022-02-09 | 2023-08-17 | Locanabio, Inc. | Compositions and methods for modulating pre-mrna splicing |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4102099B2 (ja) | 2001-04-25 | 2008-06-18 | アンスティテュ ナシオナル ドゥ ラ ルシェルシュ アグロノミック | 細胞質雄性不稔から可稔への回復に関与するタンパク質及びそれをコードする遺伝子 |
| CA2445700C (en) * | 2001-04-25 | 2012-04-17 | Mitsubishi Chemical Corporation | Protein involved in restoration of cytoplasmic male sterility to fertility and gene encoding the protein and gene |
| JP2002355041A (ja) * | 2001-04-25 | 2002-12-10 | Mitsubishi Chemicals Corp | 細胞質雄性不稔から可稔への回復に関与する遺伝子 |
| US20040117868A1 (en) | 2002-01-29 | 2004-06-17 | Jun Imamura | Protein participating in restoration from cytoplasmic male sterility to fertility and gene encoding the same |
| US20060041961A1 (en) * | 2004-03-25 | 2006-02-23 | Abad Mark S | Genes and uses for pant improvement |
| US8344122B2 (en) | 2008-03-12 | 2013-01-01 | Tohoku University | Fertility restorer gene and fertility restoration method for CW-type male sterile cytoplasm of rice |
| WO2011072246A2 (en) | 2009-12-10 | 2011-06-16 | Regents Of The University Of Minnesota | Tal effector-mediated dna modification |
| JP2013128413A (ja) | 2010-03-11 | 2013-07-04 | Kyushu Univ | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の改変方法 |
| DK2784157T3 (da) * | 2011-10-21 | 2019-10-21 | Univ Kyushu Nat Univ Corp | Designfremgangsmåde til et rna-bindende protein under anvendelse af ppr-motiv og anvendelse deraf |
| AU2013248928A1 (en) * | 2012-04-16 | 2014-12-04 | The State Board Of Higher Education On Behalf Of The University Of Oregon | Peptides for the binding of nucleotide targets |
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2012
- 2012-10-22 DK DK12841435.6T patent/DK2784157T3/da active
- 2012-10-22 ES ES12841435T patent/ES2751126T3/es active Active
- 2012-10-22 WO PCT/JP2012/077274 patent/WO2013058404A1/ja not_active Ceased
- 2012-10-22 JP JP2013539727A patent/JP6164488B2/ja active Active
- 2012-10-22 PT PT128414356T patent/PT2784157T/pt unknown
- 2012-10-22 US US14/352,697 patent/US9513283B2/en active Active
- 2012-10-22 EP EP12841435.6A patent/EP2784157B1/en active Active
- 2012-10-22 EP EP19191694.9A patent/EP3611261A1/en active Pending
- 2012-10-22 AU AU2012326971A patent/AU2012326971C1/en active Active
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2016
- 2016-10-26 US US15/335,243 patent/US9984202B2/en active Active
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2017
- 2017-06-07 JP JP2017112765A patent/JP6267388B2/ja active Active
- 2017-06-07 JP JP2017112764A patent/JP6270192B2/ja active Active
- 2017-10-31 AU AU2017254874A patent/AU2017254874B2/en active Active
- 2017-12-21 JP JP2017244765A patent/JP6454398B2/ja active Active
- 2017-12-21 JP JP2017244766A patent/JP6934644B2/ja active Active
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2018
- 2018-04-25 US US15/962,127 patent/US10340028B2/en active Active
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2019
- 2019-06-04 US US16/431,429 patent/US10679731B2/en active Active
- 2019-12-11 AU AU2019280013A patent/AU2019280013B2/en active Active
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2020
- 2020-06-05 US US16/894,295 patent/US10943671B2/en active Active
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2021
- 2021-03-08 US US17/195,449 patent/US11742056B2/en active Active
- 2021-05-21 JP JP2021086108A patent/JP7157483B2/ja active Active
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2022
- 2022-06-29 AU AU2022204654A patent/AU2022204654B2/en active Active
- 2022-09-30 JP JP2022158241A patent/JP7381133B2/ja active Active
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2023
- 2023-07-13 US US18/221,440 patent/US20240047005A1/en active Pending
- 2023-10-26 JP JP2023183886A patent/JP7590019B2/ja active Active
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2024
- 2024-11-07 JP JP2024194918A patent/JP7789426B2/ja active Active
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2025
- 2025-06-30 AU AU2025204996A patent/AU2025204996A1/en active Pending
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