JP2024509241A5 - - Google Patents

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Publication number
JP2024509241A5
JP2024509241A5 JP2023554813A JP2023554813A JP2024509241A5 JP 2024509241 A5 JP2024509241 A5 JP 2024509241A5 JP 2023554813 A JP2023554813 A JP 2023554813A JP 2023554813 A JP2023554813 A JP 2023554813A JP 2024509241 A5 JP2024509241 A5 JP 2024509241A5
Authority
JP
Japan
Application number
JP2023554813A
Other languages
Japanese (ja)
Other versions
JPWO2022190018A5 (https=
JP2024509241A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2022/052128 external-priority patent/WO2022190018A1/en
Publication of JP2024509241A publication Critical patent/JP2024509241A/ja
Publication of JPWO2022190018A5 publication Critical patent/JPWO2022190018A5/ja
Publication of JP2024509241A5 publication Critical patent/JP2024509241A5/ja
Pending legal-status Critical Current

Links

JP2023554813A 2021-03-09 2022-03-09 新規のDARPinに基づくCD123エンゲージャ Pending JP2024509241A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163158539P 2021-03-09 2021-03-09
US63/158,539 2021-03-09
US202163173227P 2021-04-09 2021-04-09
US63/173,227 2021-04-09
US202163265187P 2021-12-09 2021-12-09
US63/265,187 2021-12-09
PCT/IB2022/052128 WO2022190018A1 (en) 2021-03-09 2022-03-09 Novel darpin based cd123 engagers

Publications (3)

Publication Number Publication Date
JP2024509241A JP2024509241A (ja) 2024-02-29
JPWO2022190018A5 JPWO2022190018A5 (https=) 2025-03-18
JP2024509241A5 true JP2024509241A5 (https=) 2025-03-18

Family

ID=80820043

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023554813A Pending JP2024509241A (ja) 2021-03-09 2022-03-09 新規のDARPinに基づくCD123エンゲージャ

Country Status (6)

Country Link
US (1) US20240150475A1 (https=)
EP (1) EP4304729A1 (https=)
JP (1) JP2024509241A (https=)
AU (1) AU2022233791A1 (https=)
CA (1) CA3211368A1 (https=)
WO (1) WO2022190018A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL298168A (en) 2020-05-14 2023-01-01 Molecular Partners Ag Multispecific proteins
IL305677A (en) 2021-03-09 2023-11-01 Molecular Partners Ag Novel darpin based multi-specific t-cell engagers
EP4673159A1 (en) * 2023-02-27 2026-01-07 Molecular Partners AG Darpins for use in reducing renal accumulation of drugs
WO2024251628A1 (en) * 2023-06-06 2024-12-12 Molecular Partners Ag Recombinant cd16a binding proteins and their use
WO2025163082A1 (en) * 2024-01-31 2025-08-07 Molecular Partners Ag Dll3-specific binding constructs and their use in radiotherapy
WO2025181039A1 (en) 2024-03-01 2025-09-04 Molecular Partners Ag Therapeutic combinations comprising a multi-specific t cell engager

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SE9400088D0 (sv) 1994-01-14 1994-01-14 Kabi Pharmacia Ab Bacterial receptor structures
US6818418B1 (en) 1998-12-10 2004-11-16 Compound Therapeutics, Inc. Protein scaffolds for antibody mimics and other binding proteins
DE60140474D1 (de) 2000-09-08 2009-12-24 Univ Zuerich Sammlung von proteinen mit sich wiederholenden sequenzen (repeat proteins), die repetitive sequenzmodule enthalten
US20050053973A1 (en) 2001-04-26 2005-03-10 Avidia Research Institute Novel proteins with targeted binding
US20050048512A1 (en) 2001-04-26 2005-03-03 Avidia Research Institute Combinatorial libraries of monomer domains
US20040175756A1 (en) 2001-04-26 2004-09-09 Avidia Research Institute Methods for using combinatorial libraries of monomer domains
WO2005063815A2 (en) 2003-11-12 2005-07-14 Biogen Idec Ma Inc. Fcϝ receptor-binding polypeptide variants and methods related thereto
US20060008844A1 (en) 2004-06-17 2006-01-12 Avidia Research Institute c-Met kinase binding proteins
CA2700391A1 (en) 2007-09-24 2009-04-02 University Of Zuerich Designed armadillo repeat proteins
EP3785735A1 (en) 2008-11-03 2021-03-03 Molecular Partners AG Binding proteins inhibiting the vegf-a receptor interaction
TWI510246B (zh) 2010-04-30 2015-12-01 Molecular Partners Ag 抑制vegf-a受體交互作用的經修飾結合性蛋白質
DK2643349T3 (da) 2010-11-26 2019-11-25 Molecular Partners Ag Designede repeat-proteiner, der binder til serumalbumin
CA2877584A1 (en) 2012-06-28 2014-01-03 Molecular Partners Ag Designed ankyrin repeat proteins binding to platelet-derived growth factor
EP2738180A1 (en) 2012-11-30 2014-06-04 Molecular Partners AG Binding proteins comprising at least two binding domains against HER2.
EP2789630A1 (en) 2013-04-09 2014-10-15 EngMab AG Bispecific antibodies against CD3e and ROR1
US11453708B2 (en) 2013-05-31 2022-09-27 Molecular Partners Ag Designed ankyrin repeat proteins binding to hepatocyte growth factor
EP2839842A1 (en) 2013-08-23 2015-02-25 MacroGenics, Inc. Bi-specific monovalent diabodies that are capable of binding CD123 and CD3 and uses thereof
AU2016240220B2 (en) 2015-04-02 2019-11-21 Molecular Partners Ag Designed ankyrin repeat domains with binding specificity for serum albumin
US10717772B2 (en) 2016-09-22 2020-07-21 Molecular Partners Ag Recombinant binding proteins targeting HER2 and serum albumin, and their uses
CN121499810A (zh) * 2018-09-28 2026-02-10 剑桥企业有限公司 疫苗和方法
EP3980452A1 (en) * 2019-06-04 2022-04-13 Molecular Partners AG Recombinant 4-1bb binding proteins and their use
SG11202112925PA (en) * 2019-06-04 2021-12-30 Molecular Partners Ag Recombinant fap binding proteins and their use
US12441772B2 (en) * 2019-06-04 2025-10-14 Molecular Partners Ag Designed ankyrin repeat domain with improved stability

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