JP2023528204A5 - - Google Patents

Info

Publication number
JP2023528204A5
JP2023528204A5 JP2022568689A JP2022568689A JP2023528204A5 JP 2023528204 A5 JP2023528204 A5 JP 2023528204A5 JP 2022568689 A JP2022568689 A JP 2022568689A JP 2022568689 A JP2022568689 A JP 2022568689A JP 2023528204 A5 JP2023528204 A5 JP 2023528204A5
Authority
JP
Japan
Application number
JP2022568689A
Other languages
Japanese (ja)
Other versions
JP2023528204A (ja
JP7843711B2 (ja
JPWO2021229067A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2021/062860 external-priority patent/WO2021229067A1/en
Publication of JP2023528204A publication Critical patent/JP2023528204A/ja
Publication of JP2023528204A5 publication Critical patent/JP2023528204A5/ja
Publication of JPWO2021229067A5 publication Critical patent/JPWO2021229067A5/ja
Application granted granted Critical
Publication of JP7843711B2 publication Critical patent/JP7843711B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022568689A 2020-05-14 2021-05-14 多選択性タンパク質 Active JP7843711B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP20174847 2020-05-14
EP20174847.2 2020-05-14
EP20181498 2020-06-22
EP20181498.5 2020-06-22
PCT/EP2021/062860 WO2021229067A1 (en) 2020-05-14 2021-05-14 Multispecific proteins

Publications (4)

Publication Number Publication Date
JP2023528204A JP2023528204A (ja) 2023-07-04
JP2023528204A5 true JP2023528204A5 (https=) 2024-05-09
JPWO2021229067A5 JPWO2021229067A5 (https=) 2024-05-09
JP7843711B2 JP7843711B2 (ja) 2026-04-10

Family

ID=75904957

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022568689A Active JP7843711B2 (ja) 2020-05-14 2021-05-14 多選択性タンパク質

Country Status (13)

Country Link
US (2) US20240279290A1 (https=)
EP (1) EP4149959A1 (https=)
JP (1) JP7843711B2 (https=)
KR (1) KR20230022176A (https=)
CN (1) CN115768786A (https=)
AU (1) AU2021271129A1 (https=)
BR (1) BR112022023049A2 (https=)
CA (1) CA3178785A1 (https=)
CO (1) CO2022017445A2 (https=)
IL (1) IL298168A (https=)
MX (1) MX2022014326A (https=)
TW (1) TW202208408A (https=)
WO (1) WO2021229067A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220113492A (ko) 2019-12-11 2022-08-12 몰리큘라 파트너스 아게 변경된 표면 잔기를 갖는 설계된 안키린 반복 도메인
IL298168A (en) 2020-05-14 2023-01-01 Molecular Partners Ag Multispecific proteins
US11981710B2 (en) 2020-08-18 2024-05-14 Athebio Ag N-terminal capping modules of ankyrin repeat domains
EP3957649A1 (en) 2020-08-18 2022-02-23 Athebio AG Improved n-terminal capping modules of ankyrin repeat domains
IL305677A (en) 2021-03-09 2023-11-01 Molecular Partners Ag Novel darpin based multi-specific t-cell engagers
IL313411A (en) * 2021-12-14 2024-08-01 Molecular Partners Ag Designed repeat domains with dual binding specificity and their use
WO2025163082A1 (en) * 2024-01-31 2025-08-07 Molecular Partners Ag Dll3-specific binding constructs and their use in radiotherapy

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8601597D0 (en) 1986-01-23 1986-02-26 Wilson R H Nucleotide sequences
DE60140474D1 (de) 2000-09-08 2009-12-24 Univ Zuerich Sammlung von proteinen mit sich wiederholenden sequenzen (repeat proteins), die repetitive sequenzmodule enthalten
AR039067A1 (es) 2001-11-09 2005-02-09 Pfizer Prod Inc Anticuerpos para cd40
WO2005063815A2 (en) 2003-11-12 2005-07-14 Biogen Idec Ma Inc. Fcϝ receptor-binding polypeptide variants and methods related thereto
BRPI0517834A (pt) 2004-11-12 2008-10-21 Bayer Schering Pharma Ag vìrus da doença de newcastle recombinante
BRPI0613593A2 (pt) 2005-07-08 2011-01-18 Univ Zuerich método de teste "phage display" filamentoso, vetor de fago ou de fagomìdeo e biblioteca de vetores de fago ou fagomìdeo
CA2700391A1 (en) 2007-09-24 2009-04-02 University Of Zuerich Designed armadillo repeat proteins
EP3785735A1 (en) 2008-11-03 2021-03-03 Molecular Partners AG Binding proteins inhibiting the vegf-a receptor interaction
EP2483316A1 (en) 2009-10-02 2012-08-08 Ludwig Institute for Cancer Research Ltd. Anti-fibroblast activation protein antibodies and methods and uses thereof
TWI510246B (zh) 2010-04-30 2015-12-01 Molecular Partners Ag 抑制vegf-a受體交互作用的經修飾結合性蛋白質
DK2643349T3 (da) 2010-11-26 2019-11-25 Molecular Partners Ag Designede repeat-proteiner, der binder til serumalbumin
EP2702069A4 (en) 2011-04-29 2015-04-29 Janssen Biotech Inc IL4 / IL13 BINDING REPEAT PROTEINS AND USES THEREOF
CA2877584A1 (en) 2012-06-28 2014-01-03 Molecular Partners Ag Designed ankyrin repeat proteins binding to platelet-derived growth factor
CA2883264A1 (en) 2012-10-15 2014-04-24 Universitat Zurich Prorektorat Mnw Bispecific her2 ligands for cancer therapy
EP2738180A1 (en) 2012-11-30 2014-06-04 Molecular Partners AG Binding proteins comprising at least two binding domains against HER2.
US11453708B2 (en) 2013-05-31 2022-09-27 Molecular Partners Ag Designed ankyrin repeat proteins binding to hepatocyte growth factor
AU2016240220B2 (en) 2015-04-02 2019-11-21 Molecular Partners Ag Designed ankyrin repeat domains with binding specificity for serum albumin
US10717772B2 (en) 2016-09-22 2020-07-21 Molecular Partners Ag Recombinant binding proteins targeting HER2 and serum albumin, and their uses
AU2018247796A1 (en) * 2017-04-04 2019-08-29 F. Hoffmann-La Roche Ag Novel bispecific antigen binding molecules capable of specific binding to CD40 and to FAP
KR102782136B1 (ko) 2017-11-08 2025-03-18 쿄와 기린 가부시키가이샤 CD40과 EpCAM에 결합하는 이중특이적 항체
NZ773887A (en) 2018-10-01 2024-11-29 Hoffmann La Roche Bispecific antigen binding molecules comprising anti-fap clone 212
US12441772B2 (en) 2019-06-04 2025-10-14 Molecular Partners Ag Designed ankyrin repeat domain with improved stability
SG11202112925PA (en) 2019-06-04 2021-12-30 Molecular Partners Ag Recombinant fap binding proteins and their use
EP3980452A1 (en) 2019-06-04 2022-04-13 Molecular Partners AG Recombinant 4-1bb binding proteins and their use
CN114206943A (zh) 2019-06-04 2022-03-18 分子伴侣公司 多特异性蛋白质
KR20220113492A (ko) 2019-12-11 2022-08-12 몰리큘라 파트너스 아게 변경된 표면 잔기를 갖는 설계된 안키린 반복 도메인
CA3161319A1 (en) 2019-12-11 2021-06-17 Victor LEVITSKY Recombinant peptide-mhc complex binding proteins and their generation and use
KR20230006558A (ko) 2020-05-06 2023-01-10 몰리큘라 파트너스 아게 신규한 안키린 반복 결합 단백질 및 그의 용도
IL298168A (en) 2020-05-14 2023-01-01 Molecular Partners Ag Multispecific proteins
US20240279309A1 (en) 2020-05-14 2024-08-22 Molecular Partners Ag Recombinant cd40 binding proteins and their use
JP2023549316A (ja) 2020-11-16 2023-11-24 エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト Fapを標的としたcd40アゴニストとの併用療法
CA3202358A1 (en) 2020-12-16 2022-06-23 Andreas BOSSHART Novel slow-release prodrugs
US20240052033A1 (en) 2020-12-16 2024-02-15 Molecular Partners Ag Recombinant cd3 binding proteins and their use
TW202300644A (zh) 2021-02-24 2023-01-01 中國大陸商杭州啟函生物科技有限公司 免疫細胞中的嵌合抗原受體
AU2022233791A1 (en) 2021-03-09 2023-09-28 Molecular Partners Ag Novel darpin based cd123 engagers
JP2024509890A (ja) 2021-03-09 2024-03-05 モレキュラー パートナーズ アクチェンゲゼルシャフト プロテアーゼ切断可能なプロドラッグ
WO2022190010A1 (en) 2021-03-09 2022-09-15 Molecular Partners Ag Novel darpin based cd33 engagers
EP4319883A1 (en) 2021-04-09 2024-02-14 Molecular Partners AG Novel darpin based cd70 engagers
IL313411A (en) 2021-12-14 2024-08-01 Molecular Partners Ag Designed repeat domains with dual binding specificity and their use

Similar Documents

Publication Publication Date Title
CN305529462S (https=)
CN306600242S (https=)
CN305724683S (https=)
CN305725722S (https=)
CN306276874S (https=)
CN306279469S (https=)
CN306280936S (https=)
CN306280959S (https=)
CN306284563S (https=)
CN305529922S (https=)
CN306285242S (https=)
CN306286787S (https=)
CN306306424S (https=)
CN306563034S (https=)
CN306565483S (https=)
CN306567760S (https=)
CN305529606S (https=)
CN306675294S (https=)
CN306683279S (https=)
CN306683343S (https=)
CN306690486S (https=)
CN306731964S (https=)
CN306734272S (https=)
CN306736895S (https=)
CN306737506S (https=)