JP2024535925A5 - - Google Patents

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Publication number
JP2024535925A5
JP2024535925A5 JP2024519345A JP2024519345A JP2024535925A5 JP 2024535925 A5 JP2024535925 A5 JP 2024535925A5 JP 2024519345 A JP2024519345 A JP 2024519345A JP 2024519345 A JP2024519345 A JP 2024519345A JP 2024535925 A5 JP2024535925 A5 JP 2024535925A5
Authority
JP
Japan
Prior art keywords
amino acid
domain
modified
polypeptide
acid substitutions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024519345A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024535925A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CA2022/051445 external-priority patent/WO2023050006A1/en
Publication of JP2024535925A publication Critical patent/JP2024535925A/ja
Publication of JP2024535925A5 publication Critical patent/JP2024535925A5/ja
Pending legal-status Critical Current

Links

JP2024519345A 2021-09-29 2022-09-29 修飾されたインターロイキンp40サブユニットタンパク質及びその使用方法 Pending JP2024535925A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163249685P 2021-09-29 2021-09-29
US63/249,685 2021-09-29
PCT/CA2022/051445 WO2023050006A1 (en) 2021-09-29 2022-09-29 Modified interleukin p40 subunit proteins and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2024535925A JP2024535925A (ja) 2024-10-02
JP2024535925A5 true JP2024535925A5 (https=) 2025-09-24

Family

ID=85780291

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024519345A Pending JP2024535925A (ja) 2021-09-29 2022-09-29 修飾されたインターロイキンp40サブユニットタンパク質及びその使用方法

Country Status (9)

Country Link
US (1) US20240228567A1 (https=)
EP (1) EP4408870A4 (https=)
JP (1) JP2024535925A (https=)
KR (1) KR20240068070A (https=)
CN (1) CN118043343A (https=)
AU (1) AU2022355496A1 (https=)
CA (1) CA3232071A1 (https=)
MX (1) MX2024003940A (https=)
WO (1) WO2023050006A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI880235B (zh) 2017-11-28 2025-04-11 日商中外製藥股份有限公司 可調整配體結合活性的配體結合分子
WO2025136986A2 (en) 2023-12-18 2025-06-26 Genzyme Corporation Il-12 loss of potency muteins
WO2026020161A1 (en) 2024-07-19 2026-01-22 Cytomx Therapeutics, Inc. Activatable il-12 constructs and related compositions and methods

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019355971B2 (en) * 2018-10-03 2025-05-08 Xencor, Inc. IL-12 heterodimeric Fc-fusion proteins
JP7773991B2 (ja) * 2020-03-23 2025-11-20 ザイムワークス ビーシー インコーポレイテッド マスクされたil12融合タンパク質及びその使用方法

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