JP2024023268A5 - - Google Patents

Info

Publication number
JP2024023268A5
JP2024023268A5 JP2023191811A JP2023191811A JP2024023268A5 JP 2024023268 A5 JP2024023268 A5 JP 2024023268A5 JP 2023191811 A JP2023191811 A JP 2023191811A JP 2023191811 A JP2023191811 A JP 2023191811A JP 2024023268 A5 JP2024023268 A5 JP 2024023268A5
Authority
JP
Japan
Prior art keywords
sda
polypeptide construct
seq
amino acid
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023191811A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024023268A (ja
Filing date
Publication date
Priority claimed from PCT/EP2019/056299 external-priority patent/WO2019175250A1/en
Application filed filed Critical
Publication of JP2024023268A publication Critical patent/JP2024023268A/ja
Publication of JP2024023268A5 publication Critical patent/JP2024023268A5/ja
Pending legal-status Critical Current

Links

JP2023191811A 2018-03-13 2023-11-09 破傷風神経毒素に結合する単一ドメイン抗体 Pending JP2024023268A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP18161521 2018-03-13
EP18161521.2 2018-03-13
PCT/EP2019/056299 WO2019175250A1 (en) 2018-03-13 2019-03-13 Single domain antibodies binding to tetanus neurotoxin
JP2020545344A JP2021516682A (ja) 2018-03-13 2019-03-13 破傷風神経毒素に結合する単一ドメイン抗体

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2020545344A Division JP2021516682A (ja) 2018-03-13 2019-03-13 破傷風神経毒素に結合する単一ドメイン抗体

Publications (2)

Publication Number Publication Date
JP2024023268A JP2024023268A (ja) 2024-02-21
JP2024023268A5 true JP2024023268A5 (https=) 2026-04-22

Family

ID=61691657

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020545344A Pending JP2021516682A (ja) 2018-03-13 2019-03-13 破傷風神経毒素に結合する単一ドメイン抗体
JP2023191811A Pending JP2024023268A (ja) 2018-03-13 2023-11-09 破傷風神経毒素に結合する単一ドメイン抗体

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2020545344A Pending JP2021516682A (ja) 2018-03-13 2019-03-13 破傷風神経毒素に結合する単一ドメイン抗体

Country Status (10)

Country Link
US (2) US12054540B2 (https=)
EP (1) EP3765495A1 (https=)
JP (2) JP2021516682A (https=)
CN (2) CN117964751A (https=)
AU (2) AU2019233603B2 (https=)
BR (1) BR112020018563A2 (https=)
MA (1) MA51996A (https=)
MX (2) MX2020009507A (https=)
WO (1) WO2019175250A1 (https=)
ZA (1) ZA202403355B (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4352521A4 (en) * 2021-06-07 2025-04-02 Martino, Michael, L. DIAGNOSIS AND TREATMENT BASED ON RAPID RECOGNITION
CN117624360A (zh) * 2022-08-26 2024-03-01 南京融捷康生物科技有限公司 一种抗trem2的单域抗体及其用途

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1621554T4 (da) 1992-08-21 2012-12-17 Univ Bruxelles Immunoglobuliner blottet for lette kæder
EP0698097B1 (en) 1993-04-29 2001-08-16 Unilever N.V. Production of antibodies or (functionalized) fragments thereof derived from heavy chain immunoglobulins of camelidae
EP0739981A1 (en) * 1995-04-25 1996-10-30 Vrije Universiteit Brussel Variable fragments of immunoglobulins - use for therapeutic or veterinary purposes
GB9914861D0 (en) * 1999-06-25 1999-08-25 Imperial College Tetanus toxin polypeptides
AUPS022802A0 (en) * 2002-01-31 2002-02-21 Macfarlane Burnet Institute For Medical Research And Public Health Limited, The Anti-viral compounds
AU2004245429A1 (en) 2003-06-10 2004-12-16 Farallone Holding Bv Binding peptides: methods for their generation and use
CN104072614B (zh) * 2005-07-08 2017-04-26 生物基因Ma公司 抗-αvβ6 抗体及其用途
AU2007219159B8 (en) * 2006-01-25 2012-06-28 Roger Kingdon Craig Generation of heavy-chain only antibodies in transgenic animals
EP2650311A3 (en) 2007-11-27 2014-06-04 Ablynx N.V. Amino acid sequences directed against heterodimeric cytokines and/or their receptors and polypeptides comprising the same
CN101386648B (zh) * 2008-09-25 2012-05-30 中国人民解放军军事医学科学院微生物流行病研究所 抗b型肉毒神经毒素中和性单克隆抗体、其制备方法及用途
BRPI1014253A2 (pt) * 2009-07-02 2016-04-12 Merz Pharma Gmbh & Co Kgaa polinucleotídeo codificado um polipeptídeo de neurotoxina, vetor, célula hospedeira, anticorpo, uso de um polinucleotídeo, método para a fabricação de um polipeptídeo de neurotoxina e método para a fabricação de um medicamento
WO2011064382A1 (en) 2009-11-30 2011-06-03 Ablynx N.V. Improved amino acid sequences directed against human respiratory syncytial virus (hrsv) and polypeptides comprising the same for the prevention and/or treatment of respiratory tract infections
PL3042917T3 (pl) * 2010-08-12 2018-07-31 Eli Lilly And Company Przeciwciała przeciwko peptydowi beta amyloidu N3pGlu i ich zastosowanie
EP2655624B1 (en) 2010-12-23 2017-11-29 Biogen MA Inc. Linker peptides and polypeptides comprising same
BR112014011137A2 (pt) * 2011-11-09 2018-06-12 Merz Pharma Gmbh & Co Kgaa polinucleotídeo, vetor, célula hospedeira, polipeptídeo, anticorpo, método para a produção de um polipeptídeo, método para a produção de um medicamento
US9670275B2 (en) * 2012-01-23 2017-06-06 Ablynx N.V. Sequences directed against hepatocyte growth factor (HGF) and polypeptides comprising the same for the treatment of cancers and/or tumors
WO2013157105A1 (ja) * 2012-04-18 2013-10-24 公立大学法人大阪市立大学 ムチンサブタイプ5ac特異的ヒト化抗体およびその利用
AU2014301116B2 (en) * 2013-06-28 2019-11-14 Merz Pharma Gmbh & Co. Kgaa Means and methods for the determination of the biological activity of Neurotoxin polypeptides in cells
US11897921B2 (en) 2014-12-09 2024-02-13 New York University Propeptide fusion comprising a mutated clostridium botulinum neurotoxin and a VHH domain
CN107428840A (zh) * 2015-03-25 2017-12-01 弗劳恩霍夫应用研究促进协会 抗cd89细胞毒素的复合物
US9708412B2 (en) * 2015-05-21 2017-07-18 Harpoon Therapeutics, Inc. Trispecific binding proteins and methods of use

Similar Documents

Publication Publication Date Title
JP7046804B2 (ja) 改良された血清アルブミン結合剤
JP2024023268A5 (https=)
JP2020500510A5 (https=)
JP2011523550A5 (https=)
JP2021524275A5 (https=)
JP2012518425A5 (https=)
JP2023553697A5 (https=)
JP2008515446A5 (https=)
CN104086652B (zh) 抗o型口蹄疫病毒特异性单域抗体及其重组表达载体
CN106749667B (zh) 一种抗癌胚抗原的纳米抗体及其应用
CN111704666A (zh) 新型冠状病毒n蛋白的配对单克隆抗体及其应用
JP2023553694A5 (https=)
JP2004512824A5 (https=)
RU99101121A (ru) Полипептиды, способные к образованию антигенсвязывающих структур со специфичностью к резус-d-антигенам, днк, кодирующая их, способы их получения и применение
CN106928363B (zh) 一种FAP纳米抗体Nb12
CN117069842B (zh) 具有特定等电点的抗人bcma纳米抗体及car-t和应用
CN106928364B (zh) 一种FAP纳米抗体Nb26
CN113667011B (zh) 制备抗原结合单元的方法
JP2005518344A5 (https=)
CN106928365B (zh) 一种FAP纳米抗体Nb36
CN106928358B (zh) 一种CD105纳米抗体Nb168
CN119613551A (zh) 一种抗pd-1单域抗体及其应用
CN118667000A (zh) 抗hsa单克隆抗体及其应用
CN106928368B (zh) 一种FAP纳米抗体Nb57
JP2024546916A5 (https=)