JP2023538422A5 - - Google Patents
Info
- Publication number
- JP2023538422A5 JP2023538422A5 JP2023512669A JP2023512669A JP2023538422A5 JP 2023538422 A5 JP2023538422 A5 JP 2023538422A5 JP 2023512669 A JP2023512669 A JP 2023512669A JP 2023512669 A JP2023512669 A JP 2023512669A JP 2023538422 A5 JP2023538422 A5 JP 2023538422A5
- Authority
- JP
- Japan
- Prior art keywords
- modified
- polypeptide
- polypeptide according
- sequence
- less
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063067658P | 2020-08-19 | 2020-08-19 | |
| US63/067,658 | 2020-08-19 | ||
| PCT/IB2021/000574 WO2022038417A2 (en) | 2020-08-19 | 2021-08-19 | Modified il-18 polypeptides and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023538422A JP2023538422A (ja) | 2023-09-07 |
| JP2023538422A5 true JP2023538422A5 (https=) | 2024-08-20 |
Family
ID=78032459
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023512669A Pending JP2023538422A (ja) | 2020-08-19 | 2021-08-19 | 修飾ｉｌ－１８ポリペプチドおよびその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20220056091A1 (https=) |
| EP (1) | EP4200323A2 (https=) |
| JP (1) | JP2023538422A (https=) |
| KR (1) | KR20230052956A (https=) |
| CN (1) | CN116368148A (https=) |
| AU (1) | AU2021327861A1 (https=) |
| CA (1) | CA3189327A1 (https=) |
| IL (1) | IL300638A (https=) |
| WO (1) | WO2022038417A2 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL272635B2 (en) | 2017-09-06 | 2024-02-01 | Univ Yale | Variants of interleukin-18 and methods of use |
| JP2023550545A (ja) * | 2020-11-02 | 2023-12-01 | シムハ・アイエル－１８・インコーポレイテッド | インターロイキン－１８バリアントおよび使用の方法 |
| AU2023226512A1 (en) | 2022-02-23 | 2024-08-29 | Bright Peak Therapeutics Ag | Immune antigen specific il-18 immunocytokines and uses thereof |
| WO2024044780A1 (en) * | 2022-08-26 | 2024-02-29 | Sutro Biopharma, Inc. | Interleukin-18 variants and uses thereof |
| WO2024102587A2 (en) * | 2022-11-11 | 2024-05-16 | Mural Oncology, Inc. | Interleukin 18 variants |
| US20250186594A1 (en) * | 2023-08-23 | 2025-06-12 | Bright Peak Therapeutics Ag | Il-18 polypeptides modified with polymers |
| US12134635B1 (en) | 2023-12-29 | 2024-11-05 | Sonnet BioTherapeutics, Inc. | Interleukin 18 (IL-18) variants and fusion proteins comprising same |
| WO2025151273A1 (en) * | 2024-01-08 | 2025-07-17 | Adimab, Llc | Il-18 polypeptides and uses thereof |
| WO2025242835A1 (en) | 2024-05-22 | 2025-11-27 | Ose Immunotherapeutics | Molecules comprising masking linkers and uses thereof for the treatment of cancer |
| WO2026083296A1 (en) | 2024-10-16 | 2026-04-23 | Bright Peak Therapeutics Ag | Trispecific compositions comprising il-18, vegf binding domains, and pd-1 binding domains |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002101049A2 (en) * | 2001-03-08 | 2002-12-19 | Ares Trading S.A. | Interleukin-18 mutants, their production and use |
| EP2261244A3 (en) * | 2003-04-15 | 2011-02-23 | Glaxosmithkline LLC | Human il-18 substitution mutants and their conjugates |
| US20160107999A1 (en) | 2013-05-24 | 2016-04-21 | Synaffix B.V. | Substituted azadibenzocyclooctyne compounds and their use in metal-free click reactions |
| US10266502B2 (en) | 2014-01-24 | 2019-04-23 | Synaffix B.V. | Process for the cycloaddition of a halogenated 1,3-dipole compound with a (hetero)cycloalkyne |
| JP7128121B2 (ja) | 2016-06-28 | 2022-08-30 | ヴェンタナ メディカル システムズ， インク． | Ｉｈｃ及びｉｓｈアッセイにおけるシグナル増幅のためのクリックケミストリーの応用 |
| IL272635B2 (en) * | 2017-09-06 | 2024-02-01 | Univ Yale | Variants of interleukin-18 and methods of use |
-
2021
- 2021-08-19 CA CA3189327A patent/CA3189327A1/en active Pending
- 2021-08-19 CN CN202180071568.0A patent/CN116368148A/zh active Pending
- 2021-08-19 AU AU2021327861A patent/AU2021327861A1/en active Pending
- 2021-08-19 JP JP2023512669A patent/JP2023538422A/ja active Pending
- 2021-08-19 WO PCT/IB2021/000574 patent/WO2022038417A2/en not_active Ceased
- 2021-08-19 KR KR1020237009427A patent/KR20230052956A/ko active Pending
- 2021-08-19 US US17/406,847 patent/US20220056091A1/en active Pending
- 2021-08-19 EP EP21783575.0A patent/EP4200323A2/en active Pending
- 2021-08-19 IL IL300638A patent/IL300638A/en unknown
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