|
JPS5238680B2
(https=)
|
1972-12-27 |
1977-09-30 |
|
|
|
US4732155A
(en)
|
1985-08-27 |
1988-03-22 |
The Children's Medical Center Corporation |
Implantable chemoattractant system
|
|
US5133755A
(en)
|
1986-01-28 |
1992-07-28 |
Thm Biomedical, Inc. |
Method and apparatus for diodegradable, osteogenic, bone graft substitute device
|
|
US5658894A
(en)
|
1989-04-23 |
1997-08-19 |
The Trustees Of The University Of Pennsylvania |
Compositions for inhibiting restenosis
|
|
US5760261A
(en)
|
1990-02-28 |
1998-06-02 |
Guttag; Alvin |
Higher fatty acid derivatives of salicylic acid and salts thereof
|
|
US5661127A
(en)
|
1995-05-01 |
1997-08-26 |
The Regents Of The University Of California |
Peptide compositions with growth factor-like activity
|
|
JP3018313B2
(ja)
|
1996-02-23 |
2000-03-13 |
雪印乳業株式会社 |
骨形成促進及び骨吸収防止剤
|
|
US6875753B1
(en)
|
1996-03-14 |
2005-04-05 |
The Governors Of The University Of Alberta |
Methods for cell mobilization using in vivo treatment with hyaluronan (HA)
|
|
US20050101564A1
(en)
|
1996-04-02 |
2005-05-12 |
Pilarski Linda M. |
Methods for cell mobilization using in vivo treatment with hyaluronan (HA)
|
|
CN100374159C
(zh)
|
1998-03-17 |
2008-03-12 |
中外制药株式会社 |
一种包含il-6拮抗剂活性成分的炎性肠道疾病的预防或治疗剂
|
|
US20040031072A1
(en)
|
1999-05-06 |
2004-02-12 |
La Rosa Thomas J. |
Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement
|
|
ATE440602T1
(de)
|
1999-07-28 |
2009-09-15 |
Univ Leland Stanford Junior |
Nicotinrezeptoragonisten in stammzellen und vorlaüferzellinduktion
|
|
JP2003517858A
(ja)
|
1999-11-05 |
2003-06-03 |
ジェリジーン メディカル コーポレーション |
老齢関連の軟組織の欠陥の増強と修復
|
|
EP1114862A3
(de)
|
1999-11-17 |
2003-08-06 |
Switch Biotech Aktiengesellschaft |
Verwendung von Polypeptiden oder diese kodierende Nukleinsäuren zur Diagnose oder Behandlung von Hauterkrankungen sowie ihre Verwendung zur Identifizierung von pharmakologisch aktiven Substanzen
|
|
KR20030032922A
(ko)
|
2000-02-24 |
2003-04-26 |
싸이트 테라피스 인코포레이티드 |
세포의 동시 자극 및 농축
|
|
JP3421741B2
(ja)
|
2000-05-18 |
2003-06-30 |
筑波大学長 |
人工骨髄、血球細胞の増殖方法
|
|
CN1259973C
(zh)
|
2000-10-25 |
2006-06-21 |
中外制药株式会社 |
含有il-6拮抗剂作为有效成分的牛皮癣的预防或治疗剂
|
|
US7754217B2
(en)
|
2001-03-16 |
2010-07-13 |
Bio3 Research Srl |
HMGB1 protein inhibitors and/or antagonists for the treatment of vascular diseases
|
|
DE10121254A1
(de)
|
2001-04-30 |
2002-11-07 |
Switch Biotech Ag |
MRP8/MRP14 Heterodimers oder seiner Einzelkomponenten alleine oder in Kombination zur Behandlung und/oder Prävention von Hauterkrankungen, Wunden und/oder Wundheilungsstörungen, die durch eine verringerte Menge an MRP8/MRP14 Heterodimeren gekennzeichnet sind
|
|
EP1390058A2
(en)
|
2001-04-30 |
2004-02-25 |
Switch Biotech Aktiengesellschaft |
Mrp8/mrp14 heterodimer, or its individual components in combination, for treating and/or preventing skin diseases, wounds and/or wound-healing disturbances
|
|
US7304034B2
(en)
|
2001-05-15 |
2007-12-04 |
The Feinstein Institute For Medical Research |
Use of HMGB fragments as anti-inflammatory agents
|
|
US7220723B2
(en)
|
2001-05-15 |
2007-05-22 |
The Feinstein Institute For Medical Research |
Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents
|
|
CN100447154C
(zh)
|
2001-05-15 |
2008-12-31 |
费因斯坦医学研究学院 |
利用hmg片段作为抗炎症试剂
|
|
ITMI20011986A1
(it)
|
2001-09-25 |
2003-03-25 |
San Raffaele Centro Fond |
Metodo e composizione per l'attivazione di cellule presentanti l'antigene
|
|
CA2467557A1
(en)
|
2001-11-19 |
2003-05-30 |
Kyowa Hakko Kogyo Co., Ltd. |
Agent which mobilizes multipotential stem cells from tissues to peripheral blood
|
|
KR100930139B1
(ko)
|
2001-12-07 |
2009-12-07 |
사이토리 테라퓨틱스, 인크. |
처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한시스템 및 방법
|
|
FR2833609B1
(fr)
|
2001-12-19 |
2004-12-03 |
Natural Implant |
Dispositif de prelevement cellulaire ou tissulaire en phase active et utilisations
|
|
AU2003228099A1
(en)
|
2002-07-03 |
2004-01-23 |
Centro Cardiologico Monzino S.P.A.-Irccs |
Use of hmgb1 in the treatment of tissue damage and/or to promote tissue repair
|
|
US7553488B2
(en)
|
2002-07-05 |
2009-06-30 |
UNIVERSITé LAVAL |
Antibodies against S100A8 and S100A9 proteins for modulating inflammatory reactions
|
|
WO2004042033A2
(en)
|
2002-11-01 |
2004-05-21 |
The Board Of Trustees Of The Leland Stanford Junior University |
Circulating stem cells and uses related thereto
|
|
GB0226251D0
(en)
|
2002-11-11 |
2002-12-18 |
San Raffaele Centro Fond |
Acetylated protein
|
|
JP2006510619A
(ja)
|
2002-11-20 |
2006-03-30 |
クリティカル セラピューティクス,インコーポレイテッド |
抗炎症剤としてのhmgb断片の使用
|
|
US20040156851A1
(en)
|
2002-11-20 |
2004-08-12 |
Critical Therapeutics, Inc. |
HMGB1 combination therapies
|
|
US7470538B2
(en)
|
2002-12-05 |
2008-12-30 |
Case Western Reserve University |
Cell-based therapies for ischemia
|
|
WO2004061456A2
(de)
|
2003-01-03 |
2004-07-22 |
Alcedo Biotech Gmbh |
Verwendungen von hmgb, hmgn, hmga proteinen
|
|
US7772188B2
(en)
|
2003-01-28 |
2010-08-10 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
|
WO2004075855A2
(en)
|
2003-02-26 |
2004-09-10 |
Biomed Solutions, Llc |
Process for in vivo treatment of specific biological targets in bodily fluid
|
|
EP1608397B1
(en)
|
2003-03-28 |
2008-10-15 |
Universite Laval |
S100 protein as neutrophil activator for alleviating neutropenia in cancer treatment
|
|
CN1193092C
(zh)
|
2003-03-28 |
2005-03-16 |
浙江大学 |
骨髓间充质干细胞分离和体外扩增培养方法
|
|
US20090069227A9
(en)
|
2003-04-29 |
2009-03-12 |
Capogrossi Maurizio C |
Use of HMGB1 to promote stem cell migration and/or proliferation
|
|
AU2004242091C1
(en)
|
2003-05-07 |
2009-12-24 |
La Jolla Institute For Molecular Medicine |
Administration of hyaluronic acid to enhance the function of transplanted stem cells
|
|
US20050014255A1
(en)
|
2003-05-29 |
2005-01-20 |
Board Of Regents, The University Of Texas System |
Stem cells for clinical and commercial uses
|
|
US20060183667A1
(en)
|
2003-07-11 |
2006-08-17 |
Novo Nordisk A/S |
Stabilised insulin compositions
|
|
WO2005025604A2
(en)
|
2003-09-10 |
2005-03-24 |
The General Hospital Corporation |
Use of hmgb and hmgb fragments to decrease specific immune response
|
|
AU2004272607B2
(en)
|
2003-09-11 |
2008-11-06 |
Cornerstone Therapeutics Inc. |
Monoclonal antibodies against HMGB1
|
|
ITRM20040058A1
(it)
|
2004-02-03 |
2004-05-03 |
Marco E Bianchi |
Inibitori ed antagonisti di hmgb1 in grado di regolare la proliferazione delle cellule muscolari lisce ed endoteliali.
|
|
JP2008507505A
(ja)
|
2004-07-20 |
2008-03-13 |
プロヴィンシア・イタリアーナ・デッラ・コングレガチォーネ・フィリ・デッリマコラータ・コンセチォーネ−イスティトゥト・デルモパティコ・デッリマコラータ−アイ・アール・シー・シー・エス |
創傷治癒のためのhmgb1の使用
|
|
MX2007001155A
(es)
|
2004-07-29 |
2007-08-14 |
Creabilis Therapeutics Spa |
Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1.
|
|
JP5622351B2
(ja)
|
2004-09-03 |
2014-11-12 |
クレアビリス・セラピューティクス・エスピーエー |
プロテアーゼ抵抗性ヒトおよび非ヒトHMGB1Box−A変異体、ならびにそれらの治療/診断への使用
|
|
WO2007001422A2
(en)
|
2004-10-22 |
2007-01-04 |
Medimmune, Inc. |
High affinity antibodies against hmgb1 and methods of use thereof
|
|
KR100593397B1
(ko)
|
2004-10-27 |
2006-06-28 |
한국원자력연구소 |
중배엽 줄기세포 및/또는 p 물질을 함유하는 상처 치유또는 상처 치유 촉진제, 또는 세포 치료제
|
|
WO2006047820A1
(en)
|
2004-11-01 |
2006-05-11 |
Newsouth Innovations Pty Limited |
Use of calgranulin a and b in the promotion and inhibition of mineralized tissue formation
|
|
ITRM20050032A1
(it)
|
2005-01-21 |
2006-07-22 |
Marco E Bianchi |
Inibitori ed antagonisti di hmgb1 in grado di inibire la patogenesi e la progressione della malattia aterosclerotica.
|
|
JP5103626B2
(ja)
|
2005-01-27 |
2012-12-19 |
財団法人ヒューマンサイエンス振興財団 |
間葉系幹細胞を含む細胞シート
|
|
ES2345837T3
(es)
|
2005-03-23 |
2010-10-04 |
Biosafe S.A. |
Sistema integrado para la recogida, el procesamiento y el trasplante de subgrupos de celulas, incluyendo celulas madre adultas, para medicina regenerativa.
|
|
KR100775958B1
(ko)
|
2005-03-30 |
2007-11-13 |
김정문 |
조직재생 기능을 가지는 비활성 폴리펩티드 및 그 제조방법
|
|
WO2006114805A2
(en)
|
2005-04-28 |
2006-11-02 |
Fondazione Centro San Raffaele Del Monte Tabor |
Use of hmgb2 and hmgb3 proteins for medical applications
|
|
US20100280493A1
(en)
|
2005-06-23 |
2010-11-04 |
Asha Nayak |
Methods and Systems for Treating Injured Cardiac Tissue
|
|
WO2007011606A2
(en)
*
|
2005-07-18 |
2007-01-25 |
Critical Therapeutics, Inc. |
USE OF HMGBl ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY SKIN CONDITIONS
|
|
WO2007015546A1
(ja)
|
2005-08-04 |
2007-02-08 |
Genomix Co., Ltd |
間葉系幹細胞誘導剤及び組織再生促進剤並びに間葉系幹細胞の調製方法
|
|
WO2007031100A1
(en)
|
2005-09-14 |
2007-03-22 |
Ostini, Marco |
Active immunotherapy of life-threatening systemic inflammation
|
|
US20090155853A1
(en)
|
2005-11-18 |
2009-06-18 |
Gary Nabel |
Non-viral gene delivery complex
|
|
WO2007076200A2
(en)
|
2005-11-28 |
2007-07-05 |
Medimmune, Inc. |
Antagonists of hmgb1 and/or rage and methods of use thereof
|
|
CA2640087A1
(en)
|
2006-01-25 |
2007-08-02 |
Mount Sinai School Of Medicine |
Methods and compositions for modulating the mobilization of stem cells
|
|
US7829097B2
(en)
|
2006-02-06 |
2010-11-09 |
University Of Pittsburgh - Of The Commonwealth System Of Higher Education |
Use of HMGB1 for protection against ischemia reperfusion injury
|
|
JP4982739B2
(ja)
|
2006-06-01 |
2012-07-25 |
国立大学法人 東京医科歯科大学 |
ポリグルタミン病の予防・治療剤
|
|
JP5244785B2
(ja)
|
2006-08-11 |
2013-07-24 |
小野薬品工業株式会社 |
ストローマ由来因子−1(sdf−1)に対するモノクローナル抗体
|
|
CA2663300C
(en)
|
2006-09-15 |
2014-10-07 |
Creabilis Therapeutics S.P.A. |
Polymer conjugates of box-a of hmgb1 and box-a variants of hmgb1
|
|
BRPI0718491A2
(pt)
|
2006-09-15 |
2013-12-03 |
Creabilis Therapeutics Spa |
Conjugados poliméricos do box-a da hmgb1 e variantes do box-a da hmbg1
|
|
ES2629086T3
(es)
|
2006-10-30 |
2017-08-07 |
Genomix Co., Ltd. |
Sustancia farmacéutica para promover la regeneración funcional de tejido dañado
|
|
PL2132221T3
(pl)
|
2007-02-28 |
2011-04-29 |
Polyphor Ltd |
Przyłączone do matrycy peptydomimetyki
|
|
CA2629652A1
(en)
|
2007-04-24 |
2008-10-24 |
Yaojiong Wu |
Compositions for preventing or treating skin defects and methods of use thereof
|
|
US8114668B2
(en)
|
2007-05-14 |
2012-02-14 |
Cardiac Pacemakers, Inc. |
Composition for cold storage of stem cells
|
|
JP5814549B2
(ja)
|
2008-04-30 |
2015-11-17 |
株式会社ジェノミックス |
損傷組織の機能的再生促進医薬
|
|
US8673580B2
(en)
|
2008-04-30 |
2014-03-18 |
Genomix Co., Ltd. |
Agent for recruitment of bone-marrow-derived pluripotent stem cell into peripheral circulation
|
|
JP5676253B2
(ja)
|
2008-04-30 |
2015-02-25 |
株式会社ジェノミックス |
生体内機能的細胞の高効率採取法
|
|
ES2609006T3
(es)
|
2009-10-16 |
2017-04-18 |
Rutgers, The State University Of New Jersey |
Procedimeinto de tratamiento de lesión crónica de tejido nervioso usando una estrategia de terapia celular
|
|
CA2773356A1
(en)
|
2009-10-20 |
2011-04-28 |
Maine Medical Center |
Compositions and methods for treating inflammation and fibrosis
|
|
JP5865703B2
(ja)
|
2009-10-28 |
2016-02-17 |
株式会社ジェノミックス |
骨髄間葉系および/または多能性幹細胞の血中動員による組織再生促進剤
|
|
EP2529235B1
(en)
|
2010-01-29 |
2019-03-06 |
Metanomics GmbH |
Means and methods for diagnosing heart failure in a subject
|
|
CN102247392A
(zh)
|
2010-05-21 |
2011-11-23 |
中国医学科学院药物研究所 |
甘草酸治疗扩张型心肌病心脏重构和心功能障碍的用途
|
|
JP5950428B2
(ja)
|
2010-08-05 |
2016-07-13 |
日東電工株式会社 |
線維化組織から正常組織を再生するための組成物
|
|
EP2613797B1
(en)
|
2010-09-09 |
2015-11-04 |
University Of Southern California |
Compositions and methods for the removal of biofilms
|
|
PT3358011T
(pt)
|
2011-04-26 |
2020-04-23 |
Univ Osaka |
Péptido para induzir a regeneração de um tecido e a sua utilização
|
|
CN102443064A
(zh)
|
2011-11-03 |
2012-05-09 |
刘誉 |
一种基于凝血酶活性的双靶向作用的嵌合多肽及其应用
|
|
ES2661500T3
(es)
|
2012-07-26 |
2018-04-02 |
Ospedale San Raffaele S.R.L. |
Variantes de HMGB1 y sus usos
|
|
KR101448800B1
(ko)
|
2012-10-24 |
2014-10-13 |
한양대학교 산학협력단 |
핵산 전달 복합체
|
|
US9688733B2
(en)
|
2012-10-25 |
2017-06-27 |
Genomix Co., Ltd. |
Method for treating spinal cord injury using HMGB1 fragment
|
|
ES2660420T3
(es)
|
2012-10-25 |
2018-03-22 |
Genomix Co., Ltd. |
Método novedoso para tratar infarto cardiaco utilizando fragmento de HMGB1
|
|
AU2014231709A1
(en)
|
2013-03-15 |
2015-10-15 |
Stemcell Technologies Inc. |
Compositions and methods for obtaining enriched mesenchymal stem cell cultures
|
|
GB2514424A
(en)
|
2013-05-25 |
2014-11-26 |
Univ Dublin |
Therapies for Cardiomyopathy
|
|
KR101636139B1
(ko)
|
2013-08-28 |
2016-07-06 |
가톨릭대학교 산학협력단 |
면역조절능이 우수한 sRAGE 과발현 간엽줄기세포 및 이를 포함하는 면역질환의 예방 또는 치료용 세포치료제 조성물
|
|
GB201508337D0
(en)
|
2015-05-15 |
2015-06-24 |
Hmgbiotech S R L |
Novel peptides
|
|
US20180161366A1
(en)
|
2015-05-20 |
2018-06-14 |
Biokine Therapeutics Ltd. |
Methods of obtaining mononuclear blood cells and uses thereof
|
|
EP3556378B1
(en)
|
2017-01-27 |
2025-03-12 |
StemRIM Inc. |
Therapeutic agent for cardiomyopathy, old myocardial infarction and chronic heart failure
|
|
US20200038486A1
(en)
|
2017-04-07 |
2020-02-06 |
StemRIM Inc. |
Therapeutic medicine for fibrous disease
|
|
CA3059544A1
(en)
|
2017-04-25 |
2018-11-01 |
Shionogi & Co., Ltd. |
Peptide for inducing regeneration of tissue, and use thereof
|
|
CN111542335A
(zh)
|
2017-12-01 |
2020-08-14 |
斯特姆里姆有限公司 |
炎症性肠病的治疗药
|
|
CN111868231B
(zh)
|
2017-12-01 |
2024-05-31 |
斯特姆里姆有限公司 |
外胚层间充质干细胞及其产生方法
|
|
US20210024594A1
(en)
|
2018-02-08 |
2021-01-28 |
StemRIM Inc. |
Therapeutic Agent for Psoriasis
|
|
WO2020071520A1
(ja)
|
2018-10-05 |
2020-04-09 |
株式会社ステムリム |
間葉系幹細胞の動員活性を有するペプチド
|
|
US12304933B2
(en)
|
2018-10-05 |
2025-05-20 |
StemRIM Inc. |
Disease treatment drug based on mesenchymal-stem-cell mobilization
|
|
WO2020158924A1
(ja)
|
2019-01-31 |
2020-08-06 |
国立大学法人大阪大学 |
母児間免疫寛容を誘導する方法
|
|
JP7561348B2
(ja)
|
2019-07-31 |
2024-10-04 |
株式会社ステムリム |
間葉系幹細胞の増殖促進または減少抑制のための組成物
|
|
IL296982B2
(en)
|
2020-04-03 |
2026-04-01 |
Stemrim Inc |
Peptide with mesenchymal stem cell migration activity
|