JP2022505585A5 - - Google Patents

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Publication number
JP2022505585A5
JP2022505585A5 JP2021521976A JP2021521976A JP2022505585A5 JP 2022505585 A5 JP2022505585 A5 JP 2022505585A5 JP 2021521976 A JP2021521976 A JP 2021521976A JP 2021521976 A JP2021521976 A JP 2021521976A JP 2022505585 A5 JP2022505585 A5 JP 2022505585A5
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JP
Japan
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JP2021521976A
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Japanese (ja)
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JP7512272B2 (ja
JPWO2020086730A5 (https=
JP2022505585A (ja
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Priority claimed from PCT/US2019/057679 external-priority patent/WO2020086730A1/en
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Publication of JP2022505585A5 publication Critical patent/JP2022505585A5/ja
Priority to JP2024102779A priority Critical patent/JP2024114820A/ja
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JP2021521976A 2018-10-23 2019-10-23 Alk2抗体及びその使用方法 Active JP7512272B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024102779A JP2024114820A (ja) 2018-10-23 2024-06-26 Alk2抗体及びその使用方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862749463P 2018-10-23 2018-10-23
US62/749,463 2018-10-23
PCT/US2019/057679 WO2020086730A1 (en) 2018-10-23 2019-10-23 Alk2 antibodies and methods of use thereof

Related Child Applications (1)

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JP2024102779A Division JP2024114820A (ja) 2018-10-23 2024-06-26 Alk2抗体及びその使用方法

Publications (4)

Publication Number Publication Date
JP2022505585A JP2022505585A (ja) 2022-01-14
JPWO2020086730A5 JPWO2020086730A5 (https=) 2022-10-18
JP2022505585A5 true JP2022505585A5 (https=) 2022-10-18
JP7512272B2 JP7512272B2 (ja) 2024-07-08

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JP2021521976A Active JP7512272B2 (ja) 2018-10-23 2019-10-23 Alk2抗体及びその使用方法
JP2024102779A Pending JP2024114820A (ja) 2018-10-23 2024-06-26 Alk2抗体及びその使用方法

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JP2024102779A Pending JP2024114820A (ja) 2018-10-23 2024-06-26 Alk2抗体及びその使用方法

Country Status (10)

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US (2) US12331124B2 (https=)
EP (1) EP3870613A4 (https=)
JP (2) JP7512272B2 (https=)
KR (1) KR102919834B1 (https=)
CN (2) CN118955715A (https=)
AU (1) AU2019364415A1 (https=)
BR (1) BR112021007660A2 (https=)
CA (1) CA3116900A1 (https=)
IL (1) IL282424A (https=)
WO (1) WO2020086730A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7504880B2 (ja) 2018-10-26 2024-06-24 ケロス セラピューティクス インコーポレイテッド Alk2阻害剤の結晶形
CN114761013A (zh) 2019-09-27 2022-07-15 迪斯克医药公司 治疗骨髓纤维化和相关病症的方法
CN115362175A (zh) * 2020-02-11 2022-11-18 瑞泽恩制药公司 抗acvr1抗体及其用途
US12508262B2 (en) 2020-04-30 2025-12-30 Keros Therapeutics, Inc. Methods of using ALK2 inhibitors
WO2021231798A1 (en) 2020-05-13 2021-11-18 Disc Medicine, Inc. Anti-hemojuvelin (hjv) antibodies for treating myelofibrosis
WO2022098812A1 (en) 2020-11-04 2022-05-12 Keros Therapeutics, Inc. Methods of treating iron overload
WO2022240948A1 (en) * 2021-05-11 2022-11-17 Keros Therapeutics, Inc. Methods of using alk2 and alk3 antibodies
WO2023081212A1 (en) * 2021-11-02 2023-05-11 Keros Therapeutics, Inc. Methods of using alk2 inhibitors
US20240150474A1 (en) * 2022-10-27 2024-05-09 Regeneron Pharmaceuticals, Inc. Anti-acvri antibodies and their use in the treatment of trauma-induced heterotopic ossification

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JP2008501781A (ja) * 2004-06-09 2008-01-24 テクニオン リサーチ アンド ディベロップメント ファウンデーション リミテッド 細胞の選択的アポトーシスのための抗体
MX2009002418A (es) 2006-09-05 2009-04-23 Medarex Inc Anticuerpos para las proteinas morfogenicas oseas y receptores de estas y metodos para su uso.
CN102548617B (zh) 2009-03-30 2017-11-07 阿塞勒隆制药公司 Bmp‑alk3拮抗剂和促进骨生长的用途
US20130089560A1 (en) 2010-03-17 2013-04-11 Oncomed Pharmaceuticals Inc Bone morphogenetic protein receptor binding agents and methods of their use
WO2012065059A2 (en) 2010-11-12 2012-05-18 The General Hospital Corporation Treatment of atherosclerosis with bmp-alk3 antagonists
WO2015152183A1 (ja) 2014-03-31 2015-10-08 大日本住友製薬株式会社 進行性骨化性線維異形成症の予防剤及び治療剤
US20160075772A1 (en) 2014-09-12 2016-03-17 Regeneron Pharmaceuticals, Inc. Treatment of Fibrodysplasia Ossificans Progressiva
BR112017015661A2 (pt) * 2015-01-30 2018-03-20 Saitama Medical University anticorpo anti-alk2
US10620204B2 (en) * 2015-03-26 2020-04-14 Vanderbilt University Antibody-mediated neutralization of Ebola viruses
US12428484B2 (en) 2018-12-06 2025-09-30 Alexion Pharmaceuticals, Inc. Anti-ALK2 antibodies and uses thereof
CN115362175A (zh) 2020-02-11 2022-11-18 瑞泽恩制药公司 抗acvr1抗体及其用途
JP2023530316A (ja) 2020-06-16 2023-07-14 インサイト・コーポレイション 貧血の治療のためのalk2阻害剤
WO2022098812A1 (en) 2020-11-04 2022-05-12 Keros Therapeutics, Inc. Methods of treating iron overload
WO2022098821A1 (en) 2020-11-04 2022-05-12 Keros Therapeutics, Inc. Methods of treating lymphopenia
WO2022099166A1 (en) 2020-11-09 2022-05-12 Keros Therapeutics, Inc. Methods of treating cardiovascular-related disease
WO2022240948A1 (en) 2021-05-11 2022-11-17 Keros Therapeutics, Inc. Methods of using alk2 and alk3 antibodies

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