JP2019519528A5 - - Google Patents
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- JP2019519528A5 JP2019519528A5 JP2018561641A JP2018561641A JP2019519528A5 JP 2019519528 A5 JP2019519528 A5 JP 2019519528A5 JP 2018561641 A JP2018561641 A JP 2018561641A JP 2018561641 A JP2018561641 A JP 2018561641A JP 2019519528 A5 JP2019519528 A5 JP 2019519528A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- domain monomer
- domain
- sequence
- construct
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022044109A JP7295301B2 (ja) | 2016-05-23 | 2022-03-18 | 操作されたＦｃコンストラクトに関する組成物及び方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662340322P | 2016-05-23 | 2016-05-23 | |
| US62/340,322 | 2016-05-23 | ||
| US201762443451P | 2017-01-06 | 2017-01-06 | |
| US62/443,451 | 2017-01-06 | ||
| PCT/US2017/034084 WO2017205434A1 (en) | 2016-05-23 | 2017-05-23 | Compositions and methods related to engineered fc constructs |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022044109A Division JP7295301B2 (ja) | 2016-05-23 | 2022-03-18 | 操作されたＦｃコンストラクトに関する組成物及び方法 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2019519528A JP2019519528A (ja) | 2019-07-11 |
| JP2019519528A5 true JP2019519528A5 (https=) | 2020-07-02 |
| JP7045333B2 JP7045333B2 (ja) | 2022-03-31 |
| JP7045333B6 JP7045333B6 (ja) | 2022-05-06 |
Family
ID=60412547
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018561641A Active JP7045333B6 (ja) | 2016-05-23 | 2017-05-23 | 操作されたＦｃコンストラクトに関する組成物及び方法 |
| JP2018561639A Withdrawn JP2019519527A (ja) | 2016-05-23 | 2017-05-23 | 操作されたＦｃコンストラクトに関する組成物及び方法 |
| JP2022010912A Pending JP2022068176A (ja) | 2016-05-23 | 2022-01-27 | 操作されたＦｃコンストラクトに関する組成物及び方法 |
| JP2022044109A Active JP7295301B2 (ja) | 2016-05-23 | 2022-03-18 | 操作されたＦｃコンストラクトに関する組成物及び方法 |
| JP2024193057A Withdrawn JP2025026880A (ja) | 2016-05-23 | 2024-11-01 | 操作されたＦｃコンストラクトに関する組成物及び方法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018561639A Withdrawn JP2019519527A (ja) | 2016-05-23 | 2017-05-23 | 操作されたＦｃコンストラクトに関する組成物及び方法 |
| JP2022010912A Pending JP2022068176A (ja) | 2016-05-23 | 2022-01-27 | 操作されたＦｃコンストラクトに関する組成物及び方法 |
| JP2022044109A Active JP7295301B2 (ja) | 2016-05-23 | 2022-03-18 | 操作されたＦｃコンストラクトに関する組成物及び方法 |
| JP2024193057A Withdrawn JP2025026880A (ja) | 2016-05-23 | 2024-11-01 | 操作されたＦｃコンストラクトに関する組成物及び方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US11155640B2 (https=) |
| EP (2) | EP3484514B1 (https=) |
| JP (5) | JP7045333B6 (https=) |
| KR (3) | KR102590061B1 (https=) |
| CN (4) | CN118206639A (https=) |
| AU (2) | AU2017272109B2 (https=) |
| BR (2) | BR112018074056A2 (https=) |
| CA (2) | CA3025310A1 (https=) |
| DK (1) | DK3484514T3 (https=) |
| ES (1) | ES2973251T3 (https=) |
| IL (3) | IL263211B2 (https=) |
| PL (1) | PL3484514T3 (https=) |
| SG (3) | SG11201810465RA (https=) |
| WO (2) | WO2017205436A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4299595A3 (en) | 2014-05-02 | 2024-03-13 | Momenta Pharmaceuticals, Inc. | Compositions and methods related to engineered fc constructs |
| EP3423572B1 (en) | 2016-03-02 | 2023-11-29 | Momenta Pharmaceuticals, Inc. | Methods related to engineered fc constructs |
| DK3484514T3 (da) * | 2016-05-23 | 2024-01-29 | Momenta Pharmaceuticals Inc | Compositions and methods related to engineered fc constructs |
| JP7146771B2 (ja) * | 2017-01-06 | 2022-10-04 | モメンタ ファーマシューティカルズ インコーポレイテッド | 操作されたＦｃコンストラクトに関する組成物及び方法 |
| US20210284717A1 (en) * | 2018-07-11 | 2021-09-16 | Momenta Pharmaceuticals, Inc. | Compositions and methods related to engineered fc-antigen binding domain constructs |
| CN113382749A (zh) * | 2018-07-11 | 2021-09-10 | 动量制药公司 | 与工程化Fc-抗原结合结构域构建体有关的组合物和方法 |
| CA3106212A1 (en) * | 2018-07-11 | 2020-01-16 | Momenta Pharmaceuticals, Inc. | Compositions and methods related to engineered fc-antigen binding domain constructs |
| KR20210044783A (ko) * | 2018-07-11 | 2021-04-23 | 모멘타 파머슈티컬스 인코포레이티드 | CTLA-4 표적화 조작된 Fc-항원 결합 도메인 작제물에 관련된 조성물 및 방법 |
| US20210238310A1 (en) * | 2018-07-11 | 2021-08-05 | Momenta Pharmaceuticals, Inc. | COMPOSITIONS AND METHODS RELATED TO ENGINEERED Fc-ANTIGEN BINDING DOMAIN CONSTRUCTS |
| MX2021000307A (es) * | 2018-07-11 | 2021-09-08 | Momenta Pharmaceuticals Inc | Composiciones y métodos relacionados con constructos de dominio de unión a antígeno-fc dirigidos a cd38 diseñados por ingeniería genética. |
| CA3105985A1 (en) * | 2018-07-11 | 2020-01-16 | Momenta Pharmaceuticals, Inc. | Compositions and methods related to engineered fc-antigen binding domain constructs targeted to ccr4 |
| JP2021530989A (ja) * | 2018-07-11 | 2021-11-18 | モメンタ ファーマシューティカルズ インコーポレイテッド | ＰＤ−Ｌ１を標的とした改変されたＦｃ抗原結合ドメイン構築体に関する組成物および方法 |
| KR102661494B1 (ko) | 2019-03-08 | 2024-04-29 | 에이치엘만도 주식회사 | 랙구동형 동력 보조 조향장치 |
| AU2020344164A1 (en) | 2019-09-13 | 2022-04-14 | CSL Behring Lengnau AG | Recombinant IgG Fc multimers for the treatment of immune complex-mediated kidney disorders |
| BR112022010096A2 (pt) * | 2019-12-06 | 2022-09-06 | CSL Behring Lengnau AG | Composições estáveis de multímeros fc |
| CN111808170A (zh) * | 2020-06-29 | 2020-10-23 | 江苏为真生物医药技术股份有限公司 | 多肽、hla-dr蛋白及其制备方法和应用 |
| EP4255933A4 (en) * | 2020-12-07 | 2025-07-23 | Invetx Inc | COMPOSITIONS FOR INCREASING THE HALF-LIFE OF A THERAPEUTIC AGENT IN LIVESTOCK ANIMALS AND METHODS OF USE |
| WO2024206820A1 (en) * | 2023-03-30 | 2024-10-03 | Dna Twopointo, Inc. | Fc engineering for heterodimeric antibody format |
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| FR2556219B1 (fr) | 1983-12-07 | 1987-06-26 | Merieux Inst | Nouveau medicament immunomodulateur, a base de fragments fc d'igg humaines |
| US5426641A (en) | 1994-01-28 | 1995-06-20 | Bell Communications Research, Inc. | Adaptive class AB amplifier for TDMA wireless communications systems |
| US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
| CA2257861A1 (en) | 1996-06-14 | 1997-12-18 | Smithkline Beecham Corporation | Hexameric fusion proteins and uses therefor |
| US20090074839A1 (en) | 1997-01-22 | 2009-03-19 | Marton Milankovits | Pharmaceutical Compositions Primarily for the Treatment and Prevention of Genitourinary Infections and their Extragenital Complications |
| US20020062010A1 (en) * | 1997-05-02 | 2002-05-23 | Genentech, Inc. | Method for making multispecific antibodies having heteromultimeric and common components |
| US7951917B1 (en) * | 1997-05-02 | 2011-05-31 | Genentech, Inc. | Method for making multispecific antibodies having heteromultimeric and common components |
| US6737056B1 (en) * | 1999-01-15 | 2004-05-18 | Genentech, Inc. | Polypeptide variants with altered effector function |
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| EP1697520A2 (en) | 2003-12-22 | 2006-09-06 | Xencor, Inc. | Fc polypeptides with novel fc ligand binding sites |
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| EP2158318A2 (en) | 2007-05-14 | 2010-03-03 | Biogen Idec MA, Inc. | Single-chain fc (scfc) regions, binding polypeptides comprising same, and methods related thereto |
| PL2185589T3 (pl) | 2007-06-01 | 2016-09-30 | Środki wiążące receptor regionu stałego Fc immunoglobuliny | |
| JP6157046B2 (ja) | 2008-01-07 | 2017-07-05 | アムジェン インコーポレイテッド | 静電的ステアリング（ｅｌｅｃｔｒｏｓｔａｔｉｃｓｔｅｅｒｉｎｇ）効果を用いた抗体Ｆｃヘテロ二量体分子を作製するための方法 |
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| BR112014010580B1 (pt) * | 2011-11-04 | 2021-01-12 | Zymeworks, Inc. | constructo de fc heteromultimérico isolado, composição, uso de um constructo de fc heteromultimérico isolado, composição de ácido nucléico e método para expressar o constructo de fc heteromultimérico isolado |
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| RU2727639C2 (ru) | 2014-01-15 | 2020-07-22 | Ф.Хоффманн-Ля Рош Аг | Варианты fc-области с модифицированной способностью связываться с fcrn и с сохраненной способностью связываться с белком а |
| CN113248613B (zh) | 2014-01-15 | 2024-08-23 | 豪夫迈·罗氏有限公司 | 具有修饰的FCRN结合性质的Fc区变体 |
| CA2939201A1 (en) | 2014-03-05 | 2015-09-11 | Ucb Biopharma Sprl | Multimeric fc proteins |
| MX2016010951A (es) | 2014-03-05 | 2016-11-29 | Ucb Biopharma Sprl | Proteinas de fc multimericas. |
| CA2945882A1 (en) | 2014-04-16 | 2015-10-22 | Ucb Biopharma Sprl | Multimeric fc proteins |
| EP4299595A3 (en) | 2014-05-02 | 2024-03-13 | Momenta Pharmaceuticals, Inc. | Compositions and methods related to engineered fc constructs |
| EA035419B9 (ru) * | 2014-05-29 | 2020-08-07 | Мэкроудженикс, Инк. | Триспецифичные связывающие молекулы и способы их применения |
| EP3423572B1 (en) | 2016-03-02 | 2023-11-29 | Momenta Pharmaceuticals, Inc. | Methods related to engineered fc constructs |
| DK3484514T3 (da) | 2016-05-23 | 2024-01-29 | Momenta Pharmaceuticals Inc | Compositions and methods related to engineered fc constructs |
| JP7146771B2 (ja) * | 2017-01-06 | 2022-10-04 | モメンタ ファーマシューティカルズ インコーポレイテッド | 操作されたＦｃコンストラクトに関する組成物及び方法 |
-
2017
- 2017-05-23 DK DK17803463.3T patent/DK3484514T3/da active
- 2017-05-23 KR KR1020187037345A patent/KR102590061B1/ko active Active
- 2017-05-23 IL IL263211A patent/IL263211B2/en unknown
- 2017-05-23 CN CN202410270902.0A patent/CN118206639A/zh active Pending
- 2017-05-23 BR BR112018074056-0A patent/BR112018074056A2/pt not_active Application Discontinuation
- 2017-05-23 JP JP2018561641A patent/JP7045333B6/ja active Active
- 2017-05-23 KR KR1020187037334A patent/KR102462084B1/ko active Active
- 2017-05-23 JP JP2018561639A patent/JP2019519527A/ja not_active Withdrawn
- 2017-05-23 SG SG11201810465RA patent/SG11201810465RA/en unknown
- 2017-05-23 IL IL309293A patent/IL309293A/en unknown
- 2017-05-23 PL PL17803463.3T patent/PL3484514T3/pl unknown
- 2017-05-23 WO PCT/US2017/034087 patent/WO2017205436A1/en not_active Ceased
- 2017-05-23 SG SG11201810466PA patent/SG11201810466PA/en unknown
- 2017-05-23 US US16/303,793 patent/US11155640B2/en active Active
- 2017-05-23 US US16/303,831 patent/US11623964B2/en active Active
- 2017-05-23 CN CN202210924611.XA patent/CN116063540A/zh active Pending
- 2017-05-23 BR BR112018074032-2A patent/BR112018074032A2/pt not_active Application Discontinuation
- 2017-05-23 SG SG10202011624SA patent/SG10202011624SA/en unknown
- 2017-05-23 EP EP17803463.3A patent/EP3484514B1/en active Active
- 2017-05-23 KR KR1020227037780A patent/KR102635635B1/ko active Active
- 2017-05-23 EP EP17803465.8A patent/EP3464376A4/en active Pending
- 2017-05-23 ES ES17803463T patent/ES2973251T3/es active Active
- 2017-05-23 WO PCT/US2017/034084 patent/WO2017205434A1/en not_active Ceased
- 2017-05-23 CN CN201780045688.7A patent/CN109963869A/zh active Pending
- 2017-05-23 IL IL263213A patent/IL263213B2/en unknown
- 2017-05-23 CA CA3025310A patent/CA3025310A1/en active Pending
- 2017-05-23 AU AU2017272109A patent/AU2017272109B2/en active Active
- 2017-05-23 CA CA3025306A patent/CA3025306A1/en active Pending
- 2017-05-23 AU AU2017272111A patent/AU2017272111B2/en active Active
- 2017-05-23 CN CN201780045710.8A patent/CN109789203B/zh active Active
-
2021
- 2021-10-01 US US17/491,677 patent/US12297291B2/en active Active
-
2022
- 2022-01-27 JP JP2022010912A patent/JP2022068176A/ja active Pending
- 2022-03-18 JP JP2022044109A patent/JP7295301B2/ja active Active
-
2023
- 2023-04-10 US US18/298,131 patent/US20240067757A1/en active Pending
-
2024
- 2024-11-01 JP JP2024193057A patent/JP2025026880A/ja not_active Withdrawn
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