JP2011502954A5 - - Google Patents

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JP2011502954A5
JP2011502954A5 JP2009544272A JP2009544272A JP2011502954A5 JP 2011502954 A5 JP2011502954 A5 JP 2011502954A5 JP 2009544272 A JP2009544272 A JP 2009544272A JP 2009544272 A JP2009544272 A JP 2009544272A JP 2011502954 A5 JP2011502954 A5 JP 2011502954A5
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JP2011502954A (ja
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Priority claimed from PCT/US2007/088979 external-priority patent/WO2008083239A2/en
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Publication of JP2011502954A5 publication Critical patent/JP2011502954A5/ja
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JP2009544272A 2006-12-27 2007-12-27 免疫応答を刺激する組成物および方法 Pending JP2011502954A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87731906P 2006-12-27 2006-12-27
US94974207P 2007-07-13 2007-07-13
PCT/US2007/088979 WO2008083239A2 (en) 2006-12-27 2007-12-27 Compositions and methods for stimulating an immune response

Publications (2)

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JP2011502954A JP2011502954A (ja) 2011-01-27
JP2011502954A5 true JP2011502954A5 (https=) 2011-03-10

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Family Applications (4)

Application Number Title Priority Date Filing Date
JP2009544272A Pending JP2011502954A (ja) 2006-12-27 2007-12-27 免疫応答を刺激する組成物および方法
JP2009544267A Expired - Fee Related JP5481199B2 (ja) 2006-12-27 2007-12-27 炎症および自己免疫疾患を治療するための組成物および方法
JP2013103888A Expired - Fee Related JP5926701B2 (ja) 2006-12-27 2013-05-16 炎症および自己免疫疾患を治療するための組成物および方法
JP2015229316A Withdrawn JP2016035474A (ja) 2006-12-27 2015-11-25 炎症および自己免疫疾患を治療するための組成物および方法

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2009544267A Expired - Fee Related JP5481199B2 (ja) 2006-12-27 2007-12-27 炎症および自己免疫疾患を治療するための組成物および方法
JP2013103888A Expired - Fee Related JP5926701B2 (ja) 2006-12-27 2013-05-16 炎症および自己免疫疾患を治療するための組成物および方法
JP2015229316A Withdrawn JP2016035474A (ja) 2006-12-27 2015-11-25 炎症および自己免疫疾患を治療するための組成物および方法

Country Status (6)

Country Link
US (4) US7931896B2 (https=)
EP (3) EP2109455A2 (https=)
JP (4) JP2011502954A (https=)
AU (2) AU2007339773B2 (https=)
CA (2) CA2673752A1 (https=)
WO (2) WO2008083228A2 (https=)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4626420A (en) * 1984-06-22 1986-12-02 Mizusawa Industrial Chemicals, Ltd. Synthetic fraipontite and process for preparation thereof
US6891030B2 (en) 2000-07-27 2005-05-10 Mayo Foundation For Medical Education And Research T-cell immunoregulatory molecule
EP2109455A2 (en) * 2006-12-27 2009-10-21 The Johns Hopkins University Compositions and methods for stimulating an immune response
US20090142342A1 (en) * 2006-12-27 2009-06-04 Johns Hopkins University B7-h4 receptor agonist compositions and methods for treating inflammation and auto-immune diseases
US7989173B2 (en) 2006-12-27 2011-08-02 The Johns Hopkins University Detection and diagnosis of inflammatory disorders
KR101429013B1 (ko) * 2007-07-02 2014-08-11 삼성전자주식회사 도전성 전사 롤러의 제조방법, 이로부터 제조된 전사롤러및 이를 포함하는 화상형성장치
DK2257301T3 (da) 2008-03-03 2014-04-28 Univ Miami Immunterapi baseret på allogene cancerceller.
US20110200600A1 (en) * 2008-09-10 2011-08-18 Indiana University Research And Technology Corporation Diagnosis and prognosis of immune disorders using stat4 expression
ES2666152T3 (es) * 2009-08-13 2018-05-03 The Johns Hopkins University Métodos de modulación de la función inmunitaria con anticuerpos anti-B7-H7CR
WO2011026122A2 (en) 2009-08-31 2011-03-03 Amplimmune, Inc. B7-h4 fusion proteins and methods of use thereof
WO2012145568A1 (en) * 2011-04-21 2012-10-26 Albert Einstein College Of Medicine Of Yeshiva University Antibodies to human b7x for treatment of metastatic cancer
US20130068691A1 (en) * 2011-08-05 2013-03-21 Henry John Smith Targeted apheresis for the treatment of rheumatoid arthritis and immune disorders
JP6120848B2 (ja) 2011-08-15 2017-04-26 メディミューン,エルエルシー 抗b7−h4抗体およびその使用
AU2013361275B2 (en) * 2012-12-19 2016-11-24 Amplimmune, Inc. Anti-human B7-H4 antibodies and their uses
CA2912801A1 (en) 2013-05-17 2014-11-20 Medimmune, Llc Receptors for b7-h4
WO2014194293A1 (en) 2013-05-30 2014-12-04 Amplimmune, Inc. Improved methods for the selection of patients for pd-1 or b7-h4 targeted therapies, and combination therapies thereof
CN108112254B (zh) 2015-03-13 2022-01-28 西托姆克斯治疗公司 抗-pdl1抗体、可活化的抗-pdl1抗体、及其使用方法
EP3370768B9 (en) 2015-11-03 2022-03-16 Janssen Biotech, Inc. Antibodies specifically binding pd-1 and their uses
JP2020522486A (ja) 2017-06-01 2020-07-30 サイトメックス セラピューティクス インコーポレイテッド 活性化可能抗pdl1抗体、およびその使用方法
EP3672990A1 (en) 2017-08-25 2020-07-01 Five Prime Therapeutics, Inc. B7-h4 antibodies and methods of use thereof
US12398209B2 (en) 2018-01-22 2025-08-26 Janssen Biotech, Inc. Methods of treating cancers with antagonistic anti-PD-1 antibodies
CN112566934B (zh) 2018-01-23 2024-09-17 奈斯科尔公司 B7-h4抗体及其使用方法
JP2021514379A (ja) 2018-02-21 2021-06-10 ファイブ プライム セラピューティクス, インコーポレイテッド B7−h4抗体製剤
MA52416A (fr) 2018-03-02 2021-04-21 Five Prime Therapeutics Inc Anticorps b7-h4 et leurs procédés d'utilisation
US20190345246A1 (en) * 2018-05-10 2019-11-14 TympoBio, Inc. Compositions and Methods for Treating Autoimmune Inner Ear Disease
JP2024501894A (ja) 2021-01-04 2024-01-16 メルサナ セラピューティクス インコーポレイテッド B7h4ターゲティング抗体-薬物コンジュゲートおよびその使用方法

Family Cites Families (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US202587A (en) * 1878-04-16 Improvement in door-hangers
US36107A (en) * 1862-08-05 Improvement in
US12758A (en) * 1855-04-24 chane
GB1268212A (en) * 1968-04-19 1972-03-22 Zaidan Hojin Biseibutsu Tripeptide derivatives
JPS6050743B2 (ja) * 1976-06-02 1985-11-09 旭光学工業株式会社 アパタイト焼結体及びその製造方法
US4272398A (en) * 1978-08-17 1981-06-09 The United States Of America As Represented By The Secretary Of Agriculture Microencapsulation process
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US5155020A (en) * 1989-03-08 1992-10-13 Health Research Inc. Recombinant poxvirus host range selection system
US4769330A (en) * 1981-12-24 1988-09-06 Health Research, Incorporated Modified vaccinia virus and methods for making and using the same
CH652145A5 (de) * 1982-01-22 1985-10-31 Sandoz Ag Verfahren zur in vitro-herstellung von hybridomen welche humane monoklonale antikoerper erzeugen.
US4650764A (en) * 1983-04-12 1987-03-17 Wisconsin Alumni Research Foundation Helper cell
US4634666A (en) * 1984-01-06 1987-01-06 The Board Of Trustees Of The Leland Stanford Junior University Human-murine hybridoma fusion partner
US5225539A (en) * 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US4861719A (en) * 1986-04-25 1989-08-29 Fred Hutchinson Cancer Research Center DNA constructs for retrovirus packaging cell lines
EP0545913B1 (en) 1986-08-18 1999-02-24 Emisphere Technologies, Inc. Delivery systems for pharmacological agents
US5260203A (en) * 1986-09-02 1993-11-09 Enzon, Inc. Single polypeptide chain binding molecules
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US4704692A (en) * 1986-09-02 1987-11-03 Ladner Robert C Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides
EP0279582A3 (en) * 1987-02-17 1989-10-18 Pharming B.V. Dna sequences to target proteins to the mammary gland for efficient secretion
US4853871A (en) * 1987-04-06 1989-08-01 Genex Corporation Computer-based method for designing stablized proteins
US4980289A (en) * 1987-04-27 1990-12-25 Wisconsin Alumni Research Foundation Promoter deficient retroviral vector
US4861627A (en) * 1987-05-01 1989-08-29 Massachusetts Institute Of Technology Preparation of multiwall polymeric microcapsules
US5278056A (en) * 1988-02-05 1994-01-11 The Trustees Of Columbia University In The City Of New York Retroviral packaging cell lines and process of using same
US4891719A (en) * 1988-10-03 1990-01-02 Datatape Incorporated Fast closure method for a data signal channel
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5124263A (en) * 1989-01-12 1992-06-23 Wisconsin Alumni Research Foundation Recombination resistant retroviral helper cell and products produced thereby
US5225336A (en) * 1989-03-08 1993-07-06 Health Research Incorporated Recombinant poxvirus host range selection system
US5175099A (en) * 1989-05-17 1992-12-29 Research Corporation Technologies, Inc. Retrovirus-mediated secretion of recombinant products
US5240846A (en) * 1989-08-22 1993-08-31 The Regents Of The University Of Michigan Gene therapy vector for cystic fibrosis
US5013556A (en) * 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5633076A (en) * 1989-12-01 1997-05-27 Pharming Bv Method of producing a transgenic bovine or transgenic bovine embryo
EP1690934A3 (en) 1990-01-12 2008-07-30 Abgenix, Inc. Generation of xenogeneic antibodies
US5283173A (en) * 1990-01-24 1994-02-01 The Research Foundation Of State University Of New York System to detect protein-protein interactions
US5204243A (en) * 1990-02-14 1993-04-20 Health Research Incorporated Recombinant poxvirus internal cores
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
EP0585287B1 (en) 1990-07-10 1999-10-13 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
US5814318A (en) * 1990-08-29 1998-09-29 Genpharm International Inc. Transgenic non-human animals for producing heterologous antibodies
US5874299A (en) * 1990-08-29 1999-02-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5625126A (en) * 1990-08-29 1997-04-29 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5545806A (en) * 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
ATE300615T1 (de) * 1990-08-29 2005-08-15 Genpharm Int Transgene mäuse fähig zur produktion heterologer antikörper
US5770429A (en) * 1990-08-29 1998-06-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5877397A (en) * 1990-08-29 1999-03-02 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5633425A (en) * 1990-08-29 1997-05-27 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5661016A (en) * 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5789650A (en) * 1990-08-29 1998-08-04 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
AU643141B2 (en) * 1991-03-15 1993-11-04 Amgen, Inc. Pulmonary administration of granulocyte colony stimulating factor
US5871907A (en) * 1991-05-15 1999-02-16 Medical Research Council Methods for producing members of specific binding pairs
US5858657A (en) * 1992-05-15 1999-01-12 Medical Research Council Methods for producing members of specific binding pairs
US5120727A (en) * 1991-05-29 1992-06-09 American Home Products Corporation Rapamycin dimers
KR0163798B1 (ko) 1991-07-03 1999-01-15 나가따 마사오 열가성 폴리우레탄 탄성체, 그의 제조 방법, 그의 제조 장치 및 그로부터 제조한 탄성 섬유
US5202332A (en) * 1991-08-07 1993-04-13 American Home Products Corporation Rapamycin analog as immunosuppressant
US5162333A (en) * 1991-09-11 1992-11-10 American Home Products Corporation Aminodiesters of rapamycin
ES2136092T3 (es) * 1991-09-23 1999-11-16 Medical Res Council Procedimientos para la produccion de anticuerpos humanizados.
US5932448A (en) * 1991-11-29 1999-08-03 Protein Design Labs., Inc. Bispecific antibody heterodimers
US5733743A (en) * 1992-03-24 1998-03-31 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
SG49652A1 (en) 1992-03-30 1998-06-15 American Home Prod Rapamycin formulation for iv injection
US5489680A (en) * 1992-10-13 1996-02-06 American Home Products Corporation Carbamates of rapamycin
US5434260A (en) * 1992-10-13 1995-07-18 American Home Products Corporation Carbamates of rapamycin
ATE199392T1 (de) * 1992-12-04 2001-03-15 Medical Res Council Multivalente und multispezifische bindungsproteine, deren herstellung und verwendung
DE4301681C1 (de) * 1993-01-22 1994-10-20 Deutsche Aerospace Airbus Rohrverzweigung zwischen einer Luftleitung und einer Luftdusche
US5387680A (en) 1993-08-10 1995-02-07 American Home Products Corporation C-22 ring stabilized rapamycin derivatives
AU698962B2 (en) * 1993-09-14 1998-11-12 Epimmune, Inc. Alteration of immune response using pan DR-binding peptides
AU689153B2 (en) 1993-11-08 1998-03-26 Cressy, Wayne Malcolm Head restraining device
US5385908A (en) 1993-11-22 1995-01-31 American Home Products Corporation Hindered esters of rapamycin
US5912253A (en) 1993-12-17 1999-06-15 Novartis Ag Rapamycin derivatives
US5827690A (en) * 1993-12-20 1998-10-27 Genzyme Transgenics Corporatiion Transgenic production of antibodies in milk
US5877218A (en) * 1994-01-10 1999-03-02 Teva Pharmaceutical Industries, Ltd. Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives
US5362735A (en) 1994-02-23 1994-11-08 Smithkline Beecham Corporation Rapamycin derivatives
US5451569A (en) * 1994-04-19 1995-09-19 Hong Kong University Of Science And Technology R & D Corporation Limited Pulmonary drug delivery system
US5731168A (en) * 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
NZ322175A (en) 1995-11-10 1999-02-25 Elan Corp Plc Peptides which enhance transport across tissues and methods of identifying the same
US5780462A (en) * 1995-12-27 1998-07-14 American Home Products Corporation Water soluble rapamycin esters
EP0793995B1 (en) * 1996-03-05 2001-10-04 Hitachi, Ltd. Method of treating gases containing organohalogen compounds
AUPO390396A0 (en) 1996-11-29 1996-12-19 Csl Limited Novel promiscuous T helper cell epitopes
US5989591A (en) * 1997-03-14 1999-11-23 American Home Products Corporation Rapamycin formulations for oral administration
US6982323B1 (en) * 1997-12-23 2006-01-03 Alexion Pharmaceuticals, Inc. Chimeric proteins for diagnosis and treatment of diabetes
CA2328895A1 (en) 1998-06-02 1999-12-09 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
GB9814640D0 (en) 1998-07-06 1998-09-02 Fujisawa Pharmaceutical Co New use
US6015809A (en) * 1998-08-17 2000-01-18 American Home Products Corporation Photocyclized rapamycin
ATE413466T1 (de) 1998-09-02 2008-11-15 Diadexus Inc Verfahren zur diagnose, bewertung sowie bilddarstellung verschiedener krebserkrankungen
US6468546B1 (en) 1998-12-17 2002-10-22 Corixa Corporation Compositions and methods for therapy and diagnosis of ovarian cancer
US6962980B2 (en) * 1999-09-24 2005-11-08 Corixa Corporation Compositions and methods for the therapy and diagnosis of ovarian cancer
US7109292B2 (en) * 1999-03-08 2006-09-19 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
WO2001001137A1 (en) * 1999-06-30 2001-01-04 Children's Medical Center Corporation Fusion protein and uses thereof
DE19937656A1 (de) * 1999-08-13 2001-02-15 Aventis Behring Gmbh Verwendung von Antithrombin III zur Prophylaxe und Therapie von Erkrankungen
AU2001273194A1 (en) * 2000-06-30 2002-01-14 Amgen Inc. B7-Like Molecules and Uses Thereof
US6537968B1 (en) * 2000-07-24 2003-03-25 Alphamed Pharmaceuticals Corp Treatment of lupus erythematosus
US6891030B2 (en) * 2000-07-27 2005-05-10 Mayo Foundation For Medical Education And Research T-cell immunoregulatory molecule
US7975021B2 (en) * 2000-10-23 2011-07-05 Clearplay, Inc. Method and user interface for downloading audio and video content filters to a media player
WO2002064834A1 (en) * 2001-01-04 2002-08-22 Myriad Genetics, Inc. Novel two-hybrid system and use thereof
ES2398099T3 (es) * 2001-02-19 2013-03-13 Merck Patent Gmbh Anticuerpos anti-EGFR modificados con inmunogenicidad reducida
US20050215727A1 (en) * 2001-05-01 2005-09-29 Corium Water-absorbent adhesive compositions and associated methods of manufacture and use
IL150013A (en) * 2002-06-04 2007-06-17 Gil Hecht Rotary cutting tool
US7304149B2 (en) * 2002-06-20 2007-12-04 Washington University In St. Louis BTLA nucleic acids
WO2004022594A2 (en) * 2002-09-06 2004-03-18 Cytos Biotechnology Ag Immune modulatory compounds and methods
US7449300B2 (en) * 2002-11-21 2008-11-11 Mayo Foundation For Medical Education And Research Detection of antibodies specific for B7-H1 in subjects with diseases or pathological conditions mediated by activated T cells
US20050163772A1 (en) * 2003-06-16 2005-07-28 University Of Washington B7S1: an immune modulator
US7334413B2 (en) * 2004-05-07 2008-02-26 Rosemount Aerospace Inc. Apparatus, system and method for observing combustion conditions in a gas turbine engine
DE102004060403A1 (de) * 2004-12-14 2006-07-06 Trützschler GmbH & Co KG Vorrichtung in der Spinnereivorbereitung zur Speisung einer Mehrzahl von Füllschächten, insbesondere Mischer, mit Fasermaterial
US7694100B2 (en) * 2004-12-20 2010-04-06 Intel Corporation Managing system memory resident device management queues
KR20070104673A (ko) * 2005-03-23 2007-10-26 화이자 프로덕츠 인코포레이티드 암의 치료를 위한 항-ctla4 항체와 인돌리논병용요법
CN101355965A (zh) * 2005-06-08 2009-01-28 达纳-法伯癌症研究院 通过抑制程序性细胞死亡1(pd-1)途经治疗持续性感染和癌症的方法及组合物
US20070039150A1 (en) * 2005-08-08 2007-02-22 Thomas David L Convertible furniture system comprised of modular convertible box frames and methods of forming various furniture configurations therefrom
KR100779170B1 (ko) * 2005-08-16 2007-11-23 학교법인 포항공과대학교 광양자테 홀 발광소자의 버트 커플링 방법
JP4730263B2 (ja) * 2005-09-21 2011-07-20 富士ゼロックス株式会社 画像処理装置の保守システム
US8241621B2 (en) * 2006-12-18 2012-08-14 Medistem Laboratories Stem cell mediated treg activation/expansion for therapeutic immune modulation
EP2109455A2 (en) * 2006-12-27 2009-10-21 The Johns Hopkins University Compositions and methods for stimulating an immune response
US7989173B2 (en) * 2006-12-27 2011-08-02 The Johns Hopkins University Detection and diagnosis of inflammatory disorders
US20090142342A1 (en) * 2006-12-27 2009-06-04 Johns Hopkins University B7-h4 receptor agonist compositions and methods for treating inflammation and auto-immune diseases
CN101399708B (zh) * 2007-09-28 2012-04-04 华为技术有限公司 一种建立网络性能模型的方法和设备
EP2217250A4 (en) * 2007-11-09 2011-01-05 California Inst Of Techn IMMUNOMODULATING COMPOUNDS AND RELEVANT COMPOSITIONS AND METHODS
WO2011026122A2 (en) * 2009-08-31 2011-03-03 Amplimmune, Inc. B7-h4 fusion proteins and methods of use thereof

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