|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
JPS61134325A
(ja)
|
1984-12-04 |
1986-06-21 |
Teijin Ltd |
ハイブリツド抗体遺伝子の発現方法
|
|
US5618920A
(en)
|
1985-11-01 |
1997-04-08 |
Xoma Corporation |
Modular assembly of antibody genes, antibodies prepared thereby and use
|
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
|
EP0531472B1
(en)
|
1991-03-06 |
2003-08-13 |
MERCK PATENT GmbH |
Humanized monoclonal antibodies
|
|
TW197439B
(https=)
|
1991-04-04 |
1993-01-01 |
Ueno Pharmaceutics Applic Res Co Ltd |
|
|
EP0519596B1
(en)
|
1991-05-17 |
2005-02-23 |
Merck & Co. Inc. |
A method for reducing the immunogenicity of antibody variable domains
|
|
AU669124B2
(en)
|
1991-09-18 |
1996-05-30 |
Kyowa Hakko Kirin Co., Ltd. |
Process for producing humanized chimera antibody
|
|
US5283253A
(en)
|
1991-09-23 |
1994-02-01 |
Florida State University |
Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them
|
|
ES2136092T3
(es)
|
1991-09-23 |
1999-11-16 |
Medical Res Council |
Procedimientos para la produccion de anticuerpos humanizados.
|
|
WO1993010076A1
(en)
|
1991-11-22 |
1993-05-27 |
The University Of Mississippi |
Synthesis and optical resolution of the taxol side chain and related compounds
|
|
GB9125979D0
(en)
|
1991-12-06 |
1992-02-05 |
Wellcome Found |
Antibody
|
|
ATE171472T1
(de)
|
1992-02-19 |
1998-10-15 |
Schering Corp |
Klonierung und expression von humanisierten monoklonalen antikörpern gegen menschliches interleukin-4
|
|
US5200534A
(en)
|
1992-03-13 |
1993-04-06 |
University Of Florida |
Process for the preparation of taxol and 10-deacetyltaxol
|
|
JPH08500973A
(ja)
|
1992-05-21 |
1996-02-06 |
ザ ペン ステイト リサーチ ファウンデーション |
タキソール、関連タキサン及び他の新規な抗癌／抗ウイルス性化合物原料としてのイチイ培養組織
|
|
US5274137A
(en)
|
1992-06-23 |
1993-12-28 |
Nicolaou K C |
Intermediates for preparation of taxols
|
|
US5294637A
(en)
|
1992-07-01 |
1994-03-15 |
Bristol-Myers Squibb Company |
Fluoro taxols
|
|
US5202448A
(en)
|
1992-08-14 |
1993-04-13 |
Napro Biotherapeutics, Inc. |
Processes of converting taxanes into baccatin III
|
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
|
CA2100808A1
(en)
|
1992-10-01 |
1994-04-02 |
Vittorio Farina |
Deoxy paclitaxels
|
|
FR2696462B1
(fr)
|
1992-10-05 |
1994-11-25 |
Rhone Poulenc Rorer Sa |
Procédé d'obtention de la désacétyl-10 baccatine III.
|
|
FR2696461B1
(fr)
|
1992-10-05 |
1994-11-10 |
Rhone Poulenc Rorer Sa |
Nouveaux dérivés d'analogues du taxol, leur préparation et les compositions qui les contiennent.
|
|
FR2696464B1
(fr)
|
1992-10-05 |
1994-11-10 |
Rhone Poulenc Rorer Sa |
Nouveau procédé d'estérification de la baccatine III et de la désacétyl-10 baccatine III.
|
|
FR2696458B1
(fr)
|
1992-10-05 |
1994-11-10 |
Rhone Poulenc Rorer Sa |
Procédé de préparation de dérivés du taxane.
|
|
FR2696463B1
(fr)
|
1992-10-05 |
1994-11-25 |
Rhone Poulenc Rorer Sa |
Procédé d'obtention de la désacétyl-10 baccatine III.
|
|
US5279949A
(en)
|
1992-12-07 |
1994-01-18 |
Board Of Trustees Operating Michigan State University |
Process for the isolation and purification of taxol and taxanes from Taxus spp
|
|
US5824701A
(en)
|
1993-10-20 |
1998-10-20 |
Enzon, Inc. |
Taxane-based prodrugs
|
|
US5415869A
(en)
|
1993-11-12 |
1995-05-16 |
The Research Foundation Of State University Of New York |
Taxol formulation
|
|
US5599902A
(en)
|
1994-11-10 |
1997-02-04 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Cancer inhibitory peptides
|
|
US5705154A
(en)
|
1995-03-08 |
1998-01-06 |
Schering Corporation |
Humanized monoclonal antibodies against human interleukin-4
|
|
WO1996033212A1
(fr)
|
1995-04-21 |
1996-10-24 |
Teikoku Hormone Mfg. Co., Ltd. |
Nouveaux derives peptidiques
|
|
WO1998008833A1
(en)
|
1996-08-26 |
1998-03-05 |
Bristol-Myers Squibb Company |
Sulfenamide taxane derivatives
|
|
EP0961619A4
(en)
|
1996-09-27 |
2001-09-26 |
Bristol Myers Squibb Co |
HYDROLYSABLE DRUGS FOR THE RELEASE OF ANTI-CANCER DRUGS IN METASTATIC CELLS
|
|
AU4966597A
(en)
|
1996-11-19 |
1998-06-10 |
Daiichi Pharmaceutical Co., Ltd. |
Taxol derivatives
|
|
US5977386A
(en)
|
1996-12-24 |
1999-11-02 |
Bristol-Myers Squibb Company |
6-thio-substituted paclitaxels
|
|
EP2338915A3
(en)
|
1997-04-07 |
2011-10-12 |
Genentech, Inc. |
Anti-VEGF antibodies
|
|
JP3957765B2
(ja)
|
1997-04-07 |
2007-08-15 |
ジェネンテク・インコーポレイテッド |
抗ｖｅｇｆ抗体
|
|
IL133585A0
(en)
|
1997-06-20 |
2001-04-30 |
Baker Norton Pharma |
Soluble prodrugs of paclitaxel
|
|
US7288665B1
(en)
|
1997-08-18 |
2007-10-30 |
Florida State University |
Process for selective derivatization of taxanes
|
|
JPH1192468A
(ja)
|
1997-09-17 |
1999-04-06 |
Yakult Honsha Co Ltd |
新規なタキサン誘導体
|
|
WO1999018113A1
(fr)
|
1997-10-08 |
1999-04-15 |
Bio Research Corporation Of Yokohama |
Derives taxoides et leur procede de production
|
|
US6323315B1
(en)
|
1999-09-10 |
2001-11-27 |
Basf Aktiengesellschaft |
Dolastatin peptides
|
|
US6570040B2
(en)
|
2000-03-16 |
2003-05-27 |
The Regents Of The University Of California |
Chemoselective ligation
|
|
AU2003264009A1
(en)
|
2002-08-15 |
2004-03-03 |
Epitomics, Inc. |
Humanized rabbit antibodies
|
|
EP1391213A1
(en)
|
2002-08-21 |
2004-02-25 |
Boehringer Ingelheim International GmbH |
Compositions and methods for treating cancer using maytansinoid CD44 antibody immunoconjugates and chemotherapeutic agents
|
|
EP1651659A4
(en)
|
2003-08-07 |
2008-09-17 |
Epitomics Inc |
METHOD FOR HUMANIZATION OF MONOCLONAL RABBIT ANTIBODIES
|
|
US7985783B2
(en)
|
2006-09-21 |
2011-07-26 |
The Regents Of The University Of California |
Aldehyde tags, uses thereof in site-specific protein modification
|
|
US8729232B2
(en)
|
2008-03-27 |
2014-05-20 |
The Regents Of The University Of California |
Aldehyde tags, uses thereof in site-specific protein modification
|
|
US9310374B2
(en)
*
|
2012-11-16 |
2016-04-12 |
Redwood Bioscience, Inc. |
Hydrazinyl-indole compounds and methods for producing a conjugate
|
|
WO2015081282A1
(en)
|
2013-11-27 |
2015-06-04 |
Redwood Bioscience, Inc. |
Hydrazinyl-pyrrolo compounds and methods for producing a conjugate
|
|
EP3160513B1
(en)
|
2014-06-30 |
2020-02-12 |
Glykos Finland Oy |
Saccharide derivative of a toxic payload and antibody conjugates thereof
|
|
KR20170093943A
(ko)
*
|
2014-12-09 |
2017-08-16 |
애브비 인코포레이티드 |
낮은 세포 투과성을 갖는 bcl xl 억제 화합물 및 이를 포함하는 항체 약물 접합체
|
|
PT3316909T
(pt)
*
|
2015-06-30 |
2023-11-22 |
Seattle Genetics Inc |
Anticorpos anti-ntb-a e composições e métodos relacionados
|
|
CA3063325A1
(en)
|
2017-06-21 |
2018-12-27 |
Glykos Finland Oy |
Hydrophilic linkers and conjugates thereof
|
|
CN109275190B
(zh)
*
|
2017-07-17 |
2021-10-26 |
华为技术有限公司 |
一种通信方法及装置
|
|
CA3082912A1
(en)
*
|
2017-12-11 |
2019-06-20 |
Triphase Accelerator U.S. Corporation |
Anti-cd22 antibody-maytansine conjugates, combinations, and methods of use thereof
|
|
WO2020096775A1
(en)
*
|
2018-11-09 |
2020-05-14 |
R.P. Scherer Technologies, Llc |
Sulfatase-cleavable linkers for antibody-drug conjugates
|
|
CN113874046B
(zh)
*
|
2019-01-23 |
2025-02-28 |
R.P.谢勒技术有限责任公司 |
用于抗体-药物缀合物的含有糖苷的肽接头
|
|
KR20230145332A
(ko)
|
2021-02-16 |
2023-10-17 |
글리코스 핀란드 오이 |
링커-페이로드 및 이의 컨쥬게이트
|