JP2024510927A5 - - Google Patents
Info
- Publication number
- JP2024510927A5 JP2024510927A5 JP2023553029A JP2023553029A JP2024510927A5 JP 2024510927 A5 JP2024510927 A5 JP 2024510927A5 JP 2023553029 A JP2023553029 A JP 2023553029A JP 2023553029 A JP2023553029 A JP 2023553029A JP 2024510927 A5 JP2024510927 A5 JP 2024510927A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- exist
- substituted
- pabc
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163156156P | 2021-03-03 | 2021-03-03 | |
| US63/156,156 | 2021-03-03 | ||
| US202163186581P | 2021-05-10 | 2021-05-10 | |
| US63/186,581 | 2021-05-10 | ||
| US202163214540P | 2021-06-24 | 2021-06-24 | |
| US63/214,540 | 2021-06-24 | ||
| US202163237450P | 2021-08-26 | 2021-08-26 | |
| US63/237,450 | 2021-08-26 | ||
| PCT/US2022/018534 WO2022187370A1 (en) | 2021-03-03 | 2022-03-02 | Branched linkers for antibody-drug conjugates and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024510927A JP2024510927A (ja) | 2024-03-12 |
| JP2024510927A5 true JP2024510927A5 (https=) | 2025-03-06 |
Family
ID=83155529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023553029A Pending JP2024510927A (ja) | 2021-03-03 | 2022-03-02 | 抗体－薬物コンジュゲートのための分岐リンカー及びその使用方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20240148883A1 (https=) |
| EP (1) | EP4301415A4 (https=) |
| JP (1) | JP2024510927A (https=) |
| KR (1) | KR20230165207A (https=) |
| AU (1) | AU2022230398A1 (https=) |
| BR (1) | BR112023017670A2 (https=) |
| CA (1) | CA3210473A1 (https=) |
| MX (1) | MX2023010099A (https=) |
| WO (1) | WO2022187370A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN121793989A (zh) * | 2023-07-07 | 2026-04-03 | 索尔夫治疗公司 | 药物单元和靶向单元的缀合物及其前体化合物 |
| WO2025080711A1 (en) * | 2023-10-13 | 2025-04-17 | Sutro Biopharma, Inc. | Dual payload antibody drug conjugates |
| WO2025083071A2 (en) * | 2023-10-16 | 2025-04-24 | Hummingbird Bioscience Pte. Ltd. | Antibody-drug conjugates |
| WO2025083069A1 (en) * | 2023-10-16 | 2025-04-24 | Hummingbird Bioscience Pte. Ltd. | Her2-binding molecules |
| WO2026080692A1 (en) * | 2024-10-09 | 2026-04-16 | Sutro Biopharma, Inc. | Branched beta-glucuronide linker-payloads, protein conjugates thereof, and methods thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9310374B2 (en) * | 2012-11-16 | 2016-04-12 | Redwood Bioscience, Inc. | Hydrazinyl-indole compounds and methods for producing a conjugate |
| EP3373937B1 (en) * | 2015-11-09 | 2021-12-22 | R.P. Scherer Technologies, LLC | Anti-cd22 antibody-maytansine conjugates and methods of use thereof |
| AU2016359230B2 (en) * | 2015-11-25 | 2020-04-23 | Ligachem Biosciences Inc. | Conjugates comprising self-immolative groups and methods related thereto |
| JP7381478B2 (ja) * | 2017-10-23 | 2023-11-15 | マブリンク ビオシオンス | 単一分子量ポリサルコシンを含むリガンド－薬物－複合体 |
| WO2019113248A1 (en) * | 2017-12-07 | 2019-06-13 | The Regents Of The University Of California | Anti-upar antibody-drug conjugates and methods of use thereof |
| KR20200117992A (ko) * | 2017-12-11 | 2020-10-14 | 트리페이스 리서치 앤드 디벨로프먼트 쓰리 코포레이션 | 항-cd22 항체-메이탄신 컨쥬게이트, 그것의 조합, 및 사용 방법 |
| CN119896746A (zh) * | 2019-01-23 | 2025-04-29 | R.P.谢勒技术有限责任公司 | 用于抗体-药物缀合物的含有糖苷的肽接头 |
| WO2022082397A1 (zh) * | 2020-10-19 | 2022-04-28 | 江苏时代新能源科技有限公司 | 一种电池、用电装置及制备电池的方法、设备 |
-
2022
- 2022-03-02 AU AU2022230398A patent/AU2022230398A1/en active Pending
- 2022-03-02 WO PCT/US2022/018534 patent/WO2022187370A1/en not_active Ceased
- 2022-03-02 CA CA3210473A patent/CA3210473A1/en active Pending
- 2022-03-02 BR BR112023017670A patent/BR112023017670A2/pt unknown
- 2022-03-02 US US18/276,432 patent/US20240148883A1/en active Pending
- 2022-03-02 MX MX2023010099A patent/MX2023010099A/es unknown
- 2022-03-02 JP JP2023553029A patent/JP2024510927A/ja active Pending
- 2022-03-02 KR KR1020237030693A patent/KR20230165207A/ko active Pending
- 2022-03-02 EP EP22763981.2A patent/EP4301415A4/en active Pending
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