JP2024516613A5 - - Google Patents

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Publication number
JP2024516613A5
JP2024516613A5 JP2023564508A JP2023564508A JP2024516613A5 JP 2024516613 A5 JP2024516613 A5 JP 2024516613A5 JP 2023564508 A JP2023564508 A JP 2023564508A JP 2023564508 A JP2023564508 A JP 2023564508A JP 2024516613 A5 JP2024516613 A5 JP 2024516613A5
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JP
Japan
Prior art keywords
linker
cpmb
conjugate according
gal
fam
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023564508A
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English (en)
Japanese (ja)
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JP2024516613A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/CN2022/088117 external-priority patent/WO2022222986A1/en
Publication of JP2024516613A publication Critical patent/JP2024516613A/ja
Publication of JP2024516613A5 publication Critical patent/JP2024516613A5/ja
Pending legal-status Critical Current

Links

JP2023564508A 2021-04-23 2022-04-21 肝臓細胞への薬物送達のための環状ペプチド-N-アセチルガラクトサミン(GalNAc)コンジュゲート Pending JP2024516613A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNPCT/CN2021/089305 2021-04-23
CN2021089305 2021-04-23
PCT/CN2022/088117 WO2022222986A1 (en) 2021-04-23 2022-04-21 Cyclic peptide-n-acetylgalactosamine (galnac) conjugates for drug delivery to liver cells

Publications (2)

Publication Number Publication Date
JP2024516613A JP2024516613A (ja) 2024-04-16
JP2024516613A5 true JP2024516613A5 (https=) 2025-04-25

Family

ID=83723528

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023564508A Pending JP2024516613A (ja) 2021-04-23 2022-04-21 肝臓細胞への薬物送達のための環状ペプチド-N-アセチルガラクトサミン(GalNAc)コンジュゲート

Country Status (9)

Country Link
US (1) US20240218023A1 (https=)
EP (1) EP4326744A1 (https=)
JP (1) JP2024516613A (https=)
KR (1) KR20240044385A (https=)
CN (1) CN117529490A (https=)
AU (1) AU2022261265A1 (https=)
IL (1) IL307882A (https=)
WO (1) WO2022222986A1 (https=)
ZA (1) ZA202309922B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024117938A1 (ru) * 2022-11-30 2024-06-06 Общество с ограниченной ответственностью "СИСТЕМА-БИОТЕХ" Способы получения биоконъюгатов для печень-специфической направленной модуляции протеома
WO2024152775A1 (zh) * 2023-01-17 2024-07-25 云合智药(苏州)生物科技有限公司 缀合物、配体单元及其用途
TW202517784A (zh) * 2023-07-14 2025-05-01 大陸商云合智藥(蘇州)生物科技有限公司 用於抑制己酮糖激酶表達的RNAi劑及其應用
CN120040554B (zh) * 2025-04-25 2025-07-18 云合智药(苏州)生物科技有限公司 环肽类肝靶向化合物、药物组合物及其用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8501930B2 (en) * 2010-12-17 2013-08-06 Arrowhead Madison Inc. Peptide-based in vivo siRNA delivery system
US11987647B2 (en) * 2018-05-09 2024-05-21 Ohio State Innovation Foundation Cyclic cell-penetrating peptides with one or more hydrophobic residues

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