|
AU742999B2
(en)
|
1997-08-20 |
2002-01-17 |
Warner-Lambert Company |
Naphthyridinones for inhibiting protein tyrosine kinase and cell cycle kinase mediated cellular proliferation
|
|
US6253076B1
(en)
|
1999-02-25 |
2001-06-26 |
Ericsson Inc. |
Manufacturing method for wireless communications devices employing potentially different versions of integrated circuits
|
|
EP1161431A4
(en)
|
1999-03-10 |
2002-04-24 |
Merck & Co Inc |
6-AZAINDOL COMPOUNDS AS AN ANTAGONISTS OF THE GONADOTROPIN RELEASE HORMONES
|
|
AU3396000A
(en)
|
1999-03-10 |
2000-09-28 |
Merck & Co., Inc. |
6-azaindole compounds as antagonists of gonadotropin releasing hormone
|
|
AU1053501A
(en)
|
1999-11-02 |
2001-05-14 |
Ajinomoto Co., Inc. |
Polyazanaphthalene compound and medicinal use thereof
|
|
US20030187261A1
(en)
|
2000-01-07 |
2003-10-02 |
Libor Havlicek |
Purine derivatives, process for their preparation and use thereof
|
|
US20020061892A1
(en)
|
2000-02-22 |
2002-05-23 |
Tao Wang |
Antiviral azaindole derivatives
|
|
US6469026B2
(en)
|
2000-03-24 |
2002-10-22 |
Millennium Pharmaceuticals, Inc. |
Isoquinolone inhibitors of factor Xa
|
|
US6548517B2
(en)
|
2000-03-24 |
2003-04-15 |
Millennium Pharmaceuticals, Inc. |
Oxindole inhibitors of factor Xa
|
|
US20030186972A1
(en)
|
2001-03-26 |
2003-10-02 |
Millennium Pharmaceuticals, Inc. |
Isoquinolone inhibitors of factor Xa
|
|
JP4451136B2
(ja)
|
2002-04-08 |
2010-04-14 |
メルク エンド カムパニー インコーポレーテッド |
Akt活性阻害薬
|
|
CA2485641C
(en)
|
2002-06-06 |
2010-12-14 |
Eisai Co., Ltd. |
Novel condensed imidazole derivatives
|
|
CA2492607A1
(en)
|
2002-07-25 |
2004-02-05 |
Micrologix Biotech Inc. |
Anti-viral 7-deaza d-nucleosides and uses thereof
|
|
EP2573079A3
(en)
*
|
2002-08-23 |
2015-03-11 |
Novartis AG |
Benzimidazole quinolinones and uses thereof
|
|
TWI276631B
(en)
|
2002-09-12 |
2007-03-21 |
Avanir Pharmaceuticals |
Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
|
|
NZ538936A
(en)
|
2002-09-26 |
2006-12-22 |
Eisai Co Ltd |
Combination drug comprising a combination of a dipeptidyl peptidase IV (DPPIV) inhibitor with biguanide
|
|
WO2005013950A2
(en)
|
2003-08-08 |
2005-02-17 |
Avanir Pharmaceuticals |
Selective pharmacologic inhibition of protein trafficking and related methods of treating human diseases
|
|
JP2007503388A
(ja)
|
2003-08-22 |
2007-02-22 |
アバニール・ファーマシューティカルズ |
マクロファージ遊走阻止因子の阻害剤としての置換ナフチリジン誘導体、およびヒト疾患の治療におけるそれらの使用
|
|
WO2005053695A1
(ja)
|
2003-12-04 |
2005-06-16 |
Eisai Co., Ltd. |
多発性硬化症予防剤または治療剤
|
|
JP2007513955A
(ja)
|
2003-12-09 |
2007-05-31 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
ナフチリジン誘導体およびそれらのムスカリン受容体の調節剤としての使用
|
|
GB0330043D0
(en)
*
|
2003-12-24 |
2004-01-28 |
Pharmacia Italia Spa |
Pyrrolo [2,3-b] pyridine derivatives active as kinase inhibitors process for their preparation and pharmaceutical compositions comprising them
|
|
WO2005063720A1
(ja)
*
|
2003-12-25 |
2005-07-14 |
Nippon Shinyaku Co., Ltd. |
アミド誘導体及び医薬
|
|
EP2325184A1
(en)
|
2004-06-30 |
2011-05-25 |
Vertex Pharmceuticals Incorporated |
Azaindoles useful as inhibitors of protein kinases
|
|
GB0420719D0
(en)
|
2004-09-17 |
2004-10-20 |
Addex Pharmaceuticals Sa |
Novel allosteric modulators
|
|
US20070054916A1
(en)
|
2004-10-01 |
2007-03-08 |
Amgen Inc. |
Aryl nitrogen-containing bicyclic compounds and methods of use
|
|
US8604055B2
(en)
|
2004-12-31 |
2013-12-10 |
Dr. Reddy's Laboratories Ltd. |
Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors
|
|
WO2006128172A2
(en)
|
2005-05-26 |
2006-11-30 |
Synta Pharmaceuticals Corp. |
Method for treating b cell regulated autoimmune disorders
|
|
WO2006128129A2
(en)
|
2005-05-26 |
2006-11-30 |
Synta Pharmaceuticals Corp. |
Method for treating cancer
|
|
GB0520958D0
(en)
*
|
2005-10-14 |
2005-11-23 |
Cyclacel Ltd |
Compound
|
|
KR20080092412A
(ko)
|
2006-02-06 |
2008-10-15 |
아이알엠 엘엘씨 |
단백질 키나제 억제제로서의 화합물 및 조성물
|
|
EP2010530A2
(en)
|
2006-03-23 |
2009-01-07 |
Novartis AG |
Methods for the preparation of imidazole-containing compounds
|
|
WO2007125405A2
(en)
|
2006-05-01 |
2007-11-08 |
Pfizer Products Inc. |
Substituted 2-amino-fused heterocyclic compounds
|
|
JP2009537520A
(ja)
|
2006-05-15 |
2009-10-29 |
アイアールエム・リミテッド・ライアビリティ・カンパニー |
Fgf受容体キナーゼ阻害剤のための組成物および方法
|
|
DE602006004196D1
(de)
|
2006-06-01 |
2009-01-22 |
Cellzome Ag |
Verfahren zur Identifizierung von mit ZAP-70 wechselwirkenden Molekülen und zur ZAP-70-Reinigung
|
|
BRPI0713187A2
(pt)
|
2006-07-20 |
2012-10-16 |
Mehmet Kahraman |
método de inibir rho-quinase, método de tratamento de doença mediada por rho-quinase, composto e composição farmacêutica
|
|
US7897762B2
(en)
|
2006-09-14 |
2011-03-01 |
Deciphera Pharmaceuticals, Llc |
Kinase inhibitors useful for the treatment of proliferative diseases
|
|
US8188113B2
(en)
|
2006-09-14 |
2012-05-29 |
Deciphera Pharmaceuticals, Inc. |
Dihydropyridopyrimidinyl, dihydronaphthyidinyl and related compounds useful as kinase inhibitors for the treatment of proliferative diseases
|
|
AU2007305016B2
(en)
|
2006-10-02 |
2011-11-03 |
Novartis Ag |
Compounds and compositions as protein kinase inhibitors
|
|
EP1914234A1
(en)
|
2006-10-16 |
2008-04-23 |
GPC Biotech Inc. |
Pyrido[2,3-d]pyrimidines and their use as kinase inhibitors
|
|
US8563573B2
(en)
|
2007-11-02 |
2013-10-22 |
Vertex Pharmaceuticals Incorporated |
Azaindole derivatives as CFTR modulators
|
|
DK2094702T3
(en)
|
2006-12-14 |
2015-12-07 |
Gilead Sciences Inc |
viral inhibitors
|
|
CN101842098A
(zh)
|
2007-08-10 |
2010-09-22 |
基因实验室技术有限公司 |
用于治疗病毒感染的含氮的二环化学实体
|
|
US20110160232A1
(en)
|
2007-10-04 |
2011-06-30 |
Pingda Ren |
Certain chemical entities and therapeutic uses thereof
|
|
US20110098267A1
(en)
|
2008-02-07 |
2011-04-28 |
Synta Pharmaceuticals Corporation |
Topical formulations for the treatment of psoriasis
|
|
WO2009146034A2
(en)
|
2008-03-31 |
2009-12-03 |
Takeda Pharmaceutical Company Limited |
Mapk/erk kinase inhibitors and methods of use thereof
|
|
AU2009305669A1
(en)
|
2008-10-16 |
2010-04-22 |
The Regents Of The University Of California |
Fused ring heteroaryl kinase inhibitors
|
|
US20100204265A1
(en)
|
2009-02-09 |
2010-08-12 |
Genelabs Technologies, Inc. |
Certain Nitrogen Containing Bicyclic Chemical Entities for Treating Viral Infections
|
|
FR2941948B1
(fr)
*
|
2009-02-12 |
2013-04-05 |
Nova Decision |
Derives d'azaindoles en tant qu'inhibiteur des proteines kinases abl et src
|
|
US8993604B2
(en)
|
2009-06-30 |
2015-03-31 |
Siga Technologies, Inc. |
Treatment and prevention of dengue virus infections
|
|
KR20120049852A
(ko)
|
2009-06-30 |
2012-05-17 |
시가 테크놀로지스, 인크. |
뎅기 바이러스 감염의 치료 및 예방
|
|
DE102009033208A1
(de)
|
2009-07-15 |
2011-01-20 |
Merck Patent Gmbh |
Aminopyridinderivate
|
|
ES2749504T3
(es)
|
2009-10-13 |
2020-03-20 |
Ligand Pharm Inc |
Compuestos de moléculas pequeñas miméticos del factor de crecimiento hematopoyético y sus usos
|
|
SMT201700581T1
(it)
|
2009-12-21 |
2018-01-11 |
Samumed Llc |
1h-pirazolo[3,4-b]piridine e loro usi terapeutici
|
|
WO2011094890A1
(en)
|
2010-02-02 |
2011-08-11 |
Argusina Inc. |
Phenylalanine derivatives and their use as non-peptide glp-1 receptor modulators
|
|
WO2012068406A2
(en)
|
2010-11-18 |
2012-05-24 |
Ligand Pharmaceuticals Incorporated |
Use of hematopoietic growth factor mimetics
|
|
CA2817460A1
(en)
|
2010-12-17 |
2012-06-21 |
F. Hoffmann-La Roche Ag |
Substituted 6,6-fused nitrogenous heterocyclic compounds and uses thereof
|
|
JP5990106B2
(ja)
|
2011-01-28 |
2016-09-07 |
佐藤製薬株式会社 |
縮環化合物
|
|
WO2012154888A1
(en)
|
2011-05-09 |
2012-11-15 |
Proteostasis Therapeutics, Inc. |
Compounds for treating protein folding disorders
|
|
JP2014515368A
(ja)
*
|
2011-05-26 |
2014-06-30 |
第一三共株式会社 |
プロテインキナーゼ阻害剤としての複素環化合物
|
|
EP2570125A1
(en)
|
2011-09-16 |
2013-03-20 |
Almirall, S.A. |
Ep1 receptor ligands
|
|
WO2013078254A1
(en)
|
2011-11-22 |
2013-05-30 |
Array Biopharma Inc. |
Bicyclic heteroaryl derivatives as kinase inhibitors
|
|
DE102011121022A1
(de)
|
2011-12-13 |
2013-06-13 |
Merck Patent Gmbh |
Organische Sensibilisatoren für Up- Conversion
|
|
US8461179B1
(en)
|
2012-06-07 |
2013-06-11 |
Deciphera Pharmaceuticals, Llc |
Dihydronaphthyridines and related compounds useful as kinase inhibitors for the treatment of proliferative diseases
|
|
CA2883386A1
(en)
|
2012-09-14 |
2014-03-20 |
Eternity Bioscience Inc. |
Aminoisoquinoline derivatives as protein kinase inhibitors
|
|
FR3000492B1
(fr)
*
|
2012-12-28 |
2015-09-11 |
Oribase Pharma |
Nouveaux derives azaindole en tant qu'inhibiteurs multikinases
|
|
EP2818472A1
(en)
|
2013-06-27 |
2014-12-31 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Imidazo[4,5-c]pyridine and pyrrolo[3,2-c]pyridine compounds as G-protein-coupled receptor kinase 5 (GRK5) modulators
|
|
US10471139B2
(en)
|
2013-08-15 |
2019-11-12 |
The University Of Kansas |
Toll-like receptor agonists
|
|
TWI652014B
(zh)
|
2013-09-13 |
2019-03-01 |
美商艾佛艾姆希公司 |
雜環取代之雙環唑殺蟲劑
|
|
ES2919024T3
(es)
|
2014-02-11 |
2022-07-21 |
Mitokinin Inc |
Composiciones y procedimientos que utilizan las mismas para el tratamiento de enfermedades neurodegenerativas y mitocondriales
|
|
EP3140274A1
(en)
|
2014-05-09 |
2017-03-15 |
Sloan-kettering Institute For Cancer Research |
Naphthaquinone methyltransferase inhibitors and uses thereof
|
|
GB201410815D0
(en)
|
2014-06-17 |
2014-07-30 |
Ucb Biopharma Sprl And Katholieke Universiteit Leuven |
Therapeutic agents
|
|
US20150376219A1
(en)
|
2014-06-30 |
2015-12-31 |
Minghong Zhong |
Selective Preparations of Purine Nucleosides and Nucleotides: Reagents and Methods
|
|
JP2017522324A
(ja)
|
2014-07-17 |
2017-08-10 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung |
新規ナフチリジン及びイソキノリンならびにcdk8/19阻害剤としてのその使用
|
|
WO2016014674A1
(en)
|
2014-07-22 |
2016-01-28 |
University Of Maryland, College Park |
Linked diaryl compounds with anticancer properties and methods of using the same
|
|
WO2016144706A2
(en)
|
2015-03-11 |
2016-09-15 |
Pharmakea, Inc. |
Autotaxin inhibitor compounds and uses thereof
|
|
CN107635984B
(zh)
|
2015-03-11 |
2021-04-13 |
Fmc公司 |
杂环取代的二环唑杀有害生物剂
|
|
CN107922389A
(zh)
|
2015-06-17 |
2018-04-17 |
拜耳制药股份公司 |
3‑氨基‑1,5,6,7‑四氢‑4h‑吲哚‑4‑酮
|
|
EP3322409A4
(en)
|
2015-07-15 |
2019-07-24 |
Aurigene Discovery Technologies Limited |
SUBSTITUTED AZA COMPOUNDS AS IRAQ-4 INHIBITORS
|
|
US10308629B2
(en)
|
2015-08-05 |
2019-06-04 |
Bayer Pharma Aktiengesellschaft |
1H-pyrrol-3-amines
|
|
WO2017031427A1
(en)
|
2015-08-19 |
2017-02-23 |
3-V Biosciences, Inc. |
COMPOUNDS AND METHODS FOR INHIBITING mTOR
|
|
US10696687B2
(en)
|
2015-08-20 |
2020-06-30 |
Changzhou Jiekai Pharmatech Co., Ltd. |
Pyrazolo fused heterocyclic compounds as ERK inhibitors
|
|
EP3350198A4
(en)
|
2015-09-18 |
2019-04-03 |
The Scripps Research Institute |
RNA-FOCUSED SMALL MOLECULES TO INHIBIT RNA TOXICITY IN MYOTONIC DYSTROPHY
|
|
MD3377488T2
(ro)
|
2015-11-19 |
2023-02-28 |
Incyte Corp |
Compuși heterociclici ca imunomodulatori
|
|
GB201521059D0
(en)
|
2015-11-30 |
2016-01-13 |
Isis Innovation |
Inhibitors of metallo-beta-lactamases
|
|
WO2017094750A1
(ja)
|
2015-12-01 |
2017-06-08 |
日本農薬株式会社 |
3h‐ピロロピリジン化合物若しくはそのn‐オキサイド、又はそれらの塩類及び該化合物を含有する農園芸用殺虫剤並びにその使用方法
|
|
HRP20221051T8
(hr)
|
2016-04-15 |
2023-07-21 |
Cancer Research Technology Limited |
Heterociklički spojevi kao inhibitori ret kinaze
|
|
KR102706837B1
(ko)
|
2016-04-15 |
2024-09-19 |
캔써 리서치 테크놀로지 리미티드 |
Ret 키나아제 억제제로서의 헤테로사이클릭 화합물
|
|
WO2019000683A1
(zh)
|
2017-06-30 |
2019-01-03 |
北京泰德制药股份有限公司 |
Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途
|
|
JP7311228B2
(ja)
|
2017-06-30 |
2023-07-19 |
ベイジン タイド ファーマシューティカル カンパニー リミテッド |
Rho-関連プロテインキナーゼ阻害剤、それを含む医薬組成物並びにその調製方法及び使用
|
|
US10329282B2
(en)
|
2017-06-30 |
2019-06-25 |
Beijing Tide Pharmaceutical Co., Ltd. |
Rho-associated protein kinase inhibitor, pharmaceutical composition comprising the same, as well as preparation method and use thereof
|
|
CN109721620B
(zh)
|
2017-10-27 |
2022-05-13 |
药捷安康(南京)科技股份有限公司 |
Hpk1抑制剂及其用途
|
|
WO2019113523A1
(en)
|
2017-12-08 |
2019-06-13 |
Ashok Bajji |
Compounds and therapeutic uses thereof
|
|
EP3728253B1
(en)
|
2017-12-19 |
2024-03-27 |
Bristol-Myers Squibb Company |
6-azaindole compounds
|
|
CN112105610B
(zh)
|
2018-03-13 |
2024-01-26 |
朱比连特普罗德尔有限责任公司 |
作为pd1/pd-l1相互作用/活化的抑制剂的双环化合物
|
|
TW202003430A
(zh)
|
2018-03-28 |
2020-01-16 |
美商佩樂敦治療公司 |
以HIF-2-α之抑制劑降低消化系統發炎之方法
|
|
CN112154626B
(zh)
|
2018-05-14 |
2024-08-23 |
区块链控股有限公司 |
使用区块链执行原子交换的计算机实现的系统和方法
|
|
WO2020021024A1
(en)
|
2018-07-26 |
2020-01-30 |
Phenex Pharmaceuticals Ag |
Substituted bicyclic compounds as modulators of the aryl hydrocarbon receptor (ahr)
|
|
CN117186092A
(zh)
|
2018-11-07 |
2023-12-08 |
四川科伦博泰生物医药股份有限公司 |
并环化合物、其制备方法及用途
|
|
TW202039483A
(zh)
|
2018-11-22 |
2020-11-01 |
英屬開曼群島商百濟神州有限公司 |
作為HPK1抑制劑的吡咯並[2,3-b]吡啶以及它們的用途
|
|
WO2020181050A1
(en)
|
2019-03-05 |
2020-09-10 |
Sperovie Biosciences, Inc. |
Compounds, compositions, and methods for the treatment of disease
|
|
KR20220050126A
(ko)
|
2019-06-12 |
2022-04-22 |
티엠이엠16에이 리미티드 |
호흡기 질환을 치료하기 위한 화합물
|
|
US12703697B2
(en)
|
2019-07-09 |
2026-08-11 |
Icagen, Llc |
BCAT modulation
|
|
US12459958B2
(en)
|
2019-07-17 |
2025-11-04 |
Beone Medicines I Gmbh |
Tricyclic compounds as HPK1 inhibitor and the use thereof
|
|
CN116789681B
(zh)
|
2019-08-09 |
2025-09-12 |
四川科伦博泰生物医药股份有限公司 |
含有并环基团的咪唑并嘧啶类化合物、其制备方法及用途
|
|
CR20220178A
(es)
|
2019-10-25 |
2022-06-15 |
Gilead Sciences Inc |
Compuestos moduladores de glp-1r
|
|
CA3196620A1
(en)
|
2020-10-05 |
2022-04-14 |
Enliven Therapeutics, Inc. |
5- and 6-azaindole compounds for inhibition of bcr-abl tyrosine kinases
|
|
WO2022076973A1
(en)
|
2020-10-05 |
2022-04-14 |
Enliven Therapeutics, Inc. |
7-azaindole compounds for inhibition of bcr-abl tyrosine kinases
|
|
EP4256751A1
(en)
|
2020-12-02 |
2023-10-11 |
Trock, Stanislav |
Blockchain
|
|
WO2022146920A1
(en)
*
|
2020-12-28 |
2022-07-07 |
Celgene Corporation |
Heterocyclic compounds and their use for parasitic diseases
|
|
US20240287062A1
(en)
|
2021-05-07 |
2024-08-29 |
Enliven Inc. |
Naphthyridone compounds for inhibition of raf kinases and/or bcr-abl tyrosine kinases
|
|
GB2611325A
(en)
|
2021-09-30 |
2023-04-05 |
Nchain Licensing Ag |
Propagating locking scripts
|
|
WO2024098001A1
(en)
|
2022-11-04 |
2024-05-10 |
Enliven Inc. |
Naphthyridone compounds for inhibition of raf kinases
|
|
WO2024097953A1
(en)
|
2022-11-04 |
2024-05-10 |
Enliven Inc. |
Naphthyridine compounds for inhibition of raf kinases
|
|
WO2024159094A1
(en)
|
2023-01-27 |
2024-08-02 |
Enliven Inc. |
Pyrimidinyl (hetero)aromatic aminopyridine compounds for inhibition of raf kinases
|