|
US6566118B1
(en)
|
1997-09-05 |
2003-05-20 |
Targeted Genetics Corporation |
Methods for generating high titer helper-free preparations of released recombinant AAV vectors
|
|
US6995006B2
(en)
|
1997-09-05 |
2006-02-07 |
Targeted Genetics Corporation |
Methods for generating high titer helper-free preparations of released recombinant AAV vectors
|
|
US6596535B1
(en)
|
1999-08-09 |
2003-07-22 |
Targeted Genetics Corporation |
Metabolically activated recombinant viral vectors and methods for the preparation and use
|
|
US7465583B2
(en)
|
2000-06-01 |
2008-12-16 |
The University Of North Carolina At Chapel Hill |
Duplexed parvovirus vectors
|
|
US6723551B2
(en)
|
2001-11-09 |
2004-04-20 |
The United States Of America As Represented By The Department Of Health And Human Services |
Production of adeno-associated virus in insect cells
|
|
CN103589692B
(zh)
|
2001-11-13 |
2018-07-24 |
宾夕法尼亚大学托管会 |
检测和/或鉴定腺伴随病毒(aav)序列以及分离所鉴定的新型序列的方法
|
|
US7510872B2
(en)
|
2003-02-26 |
2009-03-31 |
Nationwide Children's Hospital |
Recombinant adeno-associated virus production
|
|
JP4559429B2
(ja)
|
2003-05-21 |
2010-10-06 |
ジェンザイム・コーポレーション |
空キャプシドを実質的に含まない組換えaavビリオン調製物を生成するための方法
|
|
US7765583B2
(en)
|
2005-02-28 |
2010-07-27 |
France Telecom |
System and method for managing virtual user domains
|
|
US8283151B2
(en)
|
2005-04-29 |
2012-10-09 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Isolation, cloning and characterization of new adeno-associated virus (AAV) serotypes
|
|
US7588772B2
(en)
|
2006-03-30 |
2009-09-15 |
Board Of Trustees Of The Leland Stamford Junior University |
AAV capsid library and AAV capsid proteins
|
|
CA2660286A1
(en)
*
|
2006-08-09 |
2008-02-21 |
Homestead Clinical Corporation |
Organ-specific proteins and methods of their use
|
|
JP5956331B2
(ja)
|
2009-06-16 |
2016-07-27 |
ジェンザイム・コーポレーション |
組換えaavベクターの改良された精製方法
|
|
CN103502458B
(zh)
|
2011-02-17 |
2016-11-16 |
宾夕法尼亚大学托管会 |
用于改变组织特异性和改善aav9-介导的基因转移的组合物和方法
|
|
EP3795581A3
(en)
|
2011-08-24 |
2021-06-09 |
The Board of Trustees of the Leland Stanford Junior University |
New avv capsid proteins for nucleic acid transfer
|
|
EP3574923A1
(en)
|
2013-10-22 |
2019-12-04 |
Translate Bio, Inc. |
Mrna therapy for phenylketonuria
|
|
EP3221456B1
(en)
*
|
2014-11-21 |
2021-09-22 |
University of Florida Research Foundation, Inc. |
Genome-modified recombinant adeno-associated virus vectors
|
|
EP3562494A4
(en)
*
|
2016-12-30 |
2020-08-19 |
The Trustees Of The University Of Pennsylvania |
GENE THERAPY FOR THE TREATMENT OF PHENYLKETONURIS
|
|
KR20200057766A
(ko)
|
2017-10-02 |
2020-05-26 |
아메리칸 진 테크놀로지스 인터내셔널 인코포레이티드 |
페닐케톤뇨증을 치료하기 위한 프로모터 및 인핸서 조합을 포함하는 벡터
|
|
US11939601B2
(en)
|
2017-11-22 |
2024-03-26 |
Modernatx, Inc. |
Polynucleotides encoding phenylalanine hydroxylase for the treatment of phenylketonuria
|
|
WO2019152841A1
(en)
|
2018-02-01 |
2019-08-08 |
Homology Medicines, Inc. |
Adeno-associated virus compositions for pah gene transfer and methods of use thereof
|
|
AU2019215152A1
(en)
|
2018-02-01 |
2020-08-20 |
Homology Medicines, Inc. |
Adeno-associated virus compositions for restoring PAH gene function and methods of use thereof
|
|
KR20210008501A
(ko)
|
2018-05-09 |
2021-01-22 |
바이오마린 파머수티컬 인크. |
페닐케톤뇨증을 치료하는 방법
|
|
JP7428664B2
(ja)
*
|
2018-06-12 |
2024-02-06 |
ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル |
合成肝臓指向性アデノ随伴ウイルスカプシドおよびその使用
|
|
CN120349985A
(zh)
|
2018-10-12 |
2025-07-22 |
建新公司 |
通过肝导向基因替代疗法治疗严重pku的改良的人pah的产生
|
|
US12415002B2
(en)
|
2019-03-13 |
2025-09-16 |
Generation Bio Co. |
Non-viral DNA vectors and uses thereof for expressing phenylalanine hydroxylase (PAH) therapeutics
|
|
TW202140791A
(zh)
|
2020-01-13 |
2021-11-01 |
美商霍蒙拉奇醫藥公司 |
治療苯酮尿症之方法
|
|
WO2021144649A2
(en)
|
2020-01-16 |
2021-07-22 |
Takeda Pharmaceutical Company Limited |
Adeno associated virus based gene therapy for phenylketonuria
|
|
TW202144575A
(zh)
|
2020-04-03 |
2021-12-01 |
美商拜奧馬林製藥公司 |
使用aav及治療調配物之苯酮尿症治療
|
|
TW202208632A
(zh)
|
2020-05-27 |
2022-03-01 |
美商同源醫藥公司 |
用於恢復pah基因功能的腺相關病毒組成物及其使用方法
|
|
AU2021285812A1
(en)
|
2020-06-01 |
2023-01-05 |
Modernatx, Inc. |
Phenylalanine hydroxylase variants and uses thereof
|
|
WO2021252952A1
(en)
|
2020-06-11 |
2021-12-16 |
Sangamo Therapeutics, Inc. |
Methods and compositions for expressing phenylalanine hydroxylase
|
|
MX2023003019A
(es)
|
2020-09-16 |
2023-05-08 |
Generation Bio Co |
Vectores de adn de extremo cerrado y usos de estos para expresar fenilalanina hidroxilasa (pah).
|